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List of works by Yijuang Chern

A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease

scientific article published on 30 January 2013

A new drug design targeting the adenosinergic system for Huntington's disease

scientific article (publication date: 2011)

A novel Gαs-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor

scientific article published on 27 August 2013

AMPK-mediated regulation of neuronal metabolism and function in brain diseases

scientific article published on 29 June 2015

AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease

scientific article

Aberrant activation of AMP-activated protein kinase contributes to the abnormal distribution of HuR in amyotrophic lateral sclerosis

scientific article

Aberrant astrocytes impair vascular reactivity in Huntington disease

scientific article

Activation of AMP-activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis.

scientific article published on 25 September 2014

Adenosine A(2A) receptor up-regulates retinal wave frequency via starburst amacrine cells in the developing rat retina

scientific article

Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease

article

Adenosine receptor neurobiology: overview.

scientific article published on January 2014

Adenosine receptors activate adenylate cyclase and enhance secretion from bovine adrenal chromaffin cells in the presence of forskolin

scientific article published on May 1988

Adenosine receptors and Huntington's disease.

scientific article

An important functional role of the N terminus domain of type VI adenylyl cyclase in Galphai-mediated inhibition

scientific article published on 10 June 2004

Aspects of the general biology of adenosine A2A signaling.

scientific article published on August 2007

CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.

scientific article

Characterization of the rat A2A adenosine receptor gene: a 4.8-kb promoter-proximal DNA fragment confers selective expression in the central nervous system

scientific article published in October 2003

Circadian rhythm in the Ca(2+)-inhibitable adenylyl activity of the rat striatum

scientific article published on 01 May 1996

Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect

scientific article

Dendritic trafficking of brain‐derived neurotrophic factor mRNA: regulation by translin‐dependent and ‐independent mechanisms ⬇️

scientific article published on January 20, 2011

Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease.

scientific article

Distribution and regulation of rab3C, a small molecular weight GTP-binding protein

scientific article published in May 1994

Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease

scientific article

Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease

scientific journal article

Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown

scientific article

Elucidating the role of the A2A adenosine receptor in neurodegeneration using neurons derived from Huntington's disease iPSCs

scientific article published on 11 August 2015

Energy dysfunction in Huntington's disease: insights from PGC-1α, AMPK, and CKB.

scientific article published on 25 May 2012

Enhancement of brain-type creatine kinase activity ameliorates neuronal deficits in Huntington's disease

scientific article published on 15 February 2013

Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy

scientific article published on 22 June 2021

Equilibrative nucleoside transporter ENT1 as a biomarker of Huntington disease

scientific article

Essential role of cAMP-response element-binding protein activation by A2A adenosine receptors in rescuing the nerve growth factor-induced neurite outgrowth impaired by blockage of the MAPK cascade

scientific article

Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes

scientific article published in March 2008

Expression of type VI adenylyl cyclase in the central nervous system: implication for a potential regulator of multiple signals in different neurotransmitter systems

scientific article published in September 1998

Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington's disease

scientific article published on 02 August 2019

High Protein Diet and Huntington's Disease

scientific article published on 19 May 2015

Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models.

scientific article

Identification of nuclear factor 1 (NF1) as a transcriptional modulator of rat A(2A) adenosine receptor

scientific article published on March 2003

Impacts of methylxanthines and adenosine receptors on neurodegeneration: human and experimental studies.

scientific article published on January 2011

Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6)

scientific journal article

Inhibition of catecholamine secretion from bovine chromaffin cells by adenine nucleotides and adenosine

scientific article published on 01 May 1987

Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease

scientific article published on 3 April 2014

Insulin-dependent translocation of the small GTP-binding protein rab3C in cardiac muscle: studies on insulin-resistant Zucker rats

scientific article

Lack of type VI adenylyl cyclase (AC6) leads to abnormal sympathetic tone in neonatal mice

scientific article published on 28 May 2013

Longitudinal evaluation of an N-ethyl-N-nitrosourea-created murine model with normal pressure hydrocephalus

scientific article (publication date: 2009)

Modulation of dopamine transporter activity by nicotinic acetylcholine receptors and membrane depolarization in rat pheochromocytoma PC12 cells

scientific article published on 01 June 1999

Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma

scientific article published on 28 July 2010

N-glycosylation and residues Asn805 and Asn890 are involved in the functional properties of type VI adenylyl cyclase

scientific article published on 18 July 2001

Neuroprotective Principles from Gastrodia elata

scientific article published on 24 March 2007

Neurovascular abnormalities in brain disorders: highlights with angiogenesis and magnetic resonance imaging studies

scientific article

Neurovascular abnormalities in humans and mice with Huntington's disease

scientific article published on 10 September 2013

Novel regulation of adenylyl cyclases by direct protein-protein interactions: insights from snapin and ric8a

scientific article published on 07 February 2009

Nuclear translocation of AMPK-alpha1 potentiates striatal neurodegeneration in Huntington's disease

scientific article

PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease.

scientific article published on 25 August 2011

Presence of Na+/Ca2+ exchange activity and its role in regulation of intracellular calcium concentration in bovine adrenal chromaffin cells

scientific article published on 01 February 1992

Protein kinase C inhibits adenylyl cyclase type VI activity during desensitization of the A2a-adenosine receptor-mediated cAMP response

scientific article published in February 1997

Protein kinase C inhibits type VI adenylyl cyclase by phosphorylating the regulatory N domain and two catalytic C1 and C2 domains.

scientific article

Regulation of P-glycoprotein expression in brain capillaries in Huntington's disease and its impact on brain availability of antipsychotic agents risperidone and paliperidone

scientific article published on 13 October 2015

Regulation of adenylyl cyclase in the central nervous system.

scientific article

Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease

scientific article published on 28 December 2012

Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor

scientific article

Regulation of type VI adenylyl cyclase by Snapin, a SNAP25-binding protein

scientific article

Spt4 is selectively required for transcription of extended trinucleotide repeats

scientific article

Structural role of amino acids 99-110 in recombinant human erythropoietin

scientific article published on December 1991

Supraspinal contribution to splanchnic sympathetic activity in neonatal mouse and rat brainstem-spinal cord in vitro

scientific article

Systematic uncovering of multiple pathways underlying the pathology of Huntington disease by an acid-cleavable isotope-coded affinity tag approach

scientific article published on 31 January 2007

Targeting glial cells to elucidate the pathogenesis of Huntington's disease.

scientific article published on 28 January 2010

The 5' untranslated regions of the rat A2A adenosine receptor gene function as negative translational regulators.

scientific article published on November 1999

The A2A adenosine receptor is a dual coding gene: a novel mechanism of gene usage and signal transduction.

scientific article

The A2A adenosine receptor rescues neuritogenesis impaired by p53 blockage via KIF2A, a kinesin family member

scientific article

The A2A adenosine receptor rescues the urea cycle deficiency of Huntington's disease by enhancing the activity of the ubiquitin-proteasome system

scientific article

The adenosine analogue N6-L-phenylisopropyladenosine inhibits catecholamine secretion from bovine adrenal medulla cells by inhibiting calcium influx

scientific article published on 01 October 1992

The dysfunction of hepatic transcriptional factors in mice with Huntington's Disease

scientific article published on 30 May 2011

The influence of pathological mutations and proline substitutions in TDP-43 glycine-rich peptides on its amyloid properties and cellular toxicity.

scientific article

Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning

scientific article

Type VI adenylyl cyclase regulates neurite extension by binding to Snapin and Snap25

scientific journal article

cAMP-response element-binding protein contributes to suppression of the A2A adenosine receptor promoter by mutant Huntingtin with expanded polyglutamine residues

scientific article published on 2 February 2005

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