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List of works by Stephen L. Leib

0353. Do the noble gases helium and argon exert neuroprotective effects in a rodent cardiac arrest model?

scientific article published on 26 September 2014

0356. Effect of the neuroprotective p53-inhibitor pifithrin-µ in a rodent cardiac arrest model.

scientific article

A SAMPLE-TO-REPORT SOLUTION FOR TAXONOMIC IDENTIFICATION OF CULTURED BACTERIA IN THE CLINICAL SETTING BASED ON NANOPORE SEQUENCING

scientific article published on 30 March 2020

A case of maternal herpes simplex virus encephalitis during late pregnancy

scientific article published on January 2009

A model of cerebral aspergillosis in non-immunosuppressed nursing rats

scientific article published on 30 June 2007

A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model.

scientific article published on 4 April 2016

A tick-borne encephalitis model in infant rats infected with langat virus

scientific article published on December 2014

A transcribed enhancer dictates mesendoderm specification in pluripotency

scientific article

Adjunctive daptomycin attenuates brain damage and hearing loss more efficiently than rifampin in infant rat pneumococcal meningitis.

scientific article

Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitis

scientific article (publication date: 2011)

Adjuvant TACE inhibitor treatment improves the outcome of TLR2-/- mice with experimental pneumococcal meningitis

scientific article

Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis

scientific article

An improved simple rat model for global cerebral ischaemia by induced cardiac arrest.

scientific article published on 7 September 2015

An in vitro model of central nervous system infection and regeneration: neuronal stem cells as targets of brain damage and regenerative therapies in bacterial meningitis

scientific article published in January 2007

An infant mouse model of brain damage in pneumococcal meningitis

scientific article published on 16 October 2007

Anti-inflammatory and Oto-Protective Effect of the Small Heat Shock Protein Alpha B-Crystallin (HspB5) in Experimental Pneumococcal Meningitis.

scientific article published on 10 June 2019

Antimicrobial resistance classification using MALDI-TOF-MS is not that easy: lessons from vancomycin-resistant Enterococcus faecium

scientific article published on 01 November 2019

Apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited

scientific article

Application of Real-Time Fluorescent PCR for Quantitative Assessment of Neospora caninum Infections in Organotypic Slice Cultures of Rat Central Nervous System Tissue ⬇️

scientific article published on January 1, 2002

Atorvastatin does not alter interferon Beta-induced changes of serum matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 in patients with multiple sclerosis

scientific article published in May 2008

Atorvastatin does not alter serum levels of sCD95 and sCD95L in multiple sclerosis

scientific article

Attenuation of cerebrospinal fluid inflammation by the nonbacteriolytic antibiotic daptomycin versus that by ceftriaxone in experimental pneumococcal meningitis

scientific article

Bacterial meningitis causes two distinct forms of cellular damage in the hippocampal dentate gyrus in infant rats

scientific article published in January 2003

Bacterial meningitis impairs hippocampal neurogenesis

scientific article

Bacterial meningitis: insights into pathogenesis and evaluation of new treatment options: a perspective from experimental studies

scientific article published on 29 June 2015

Bacteriophages Improve Outcomes in Experimental Staphylococcus aureus Ventilator-associated Pneumonia

scientific article published on 01 November 2019

Brain-derived neurotrophic factor protects against multiple forms of brain injury in bacterial meningitis

scientific article published in December 2004

CHORIORETINAL NOCARDIOSIS

scientific article published on 01 January 2009

CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells

scientific article published on 08 June 2022

Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis.

scientific article published on 12 February 2003

Caspase-3 mediates in part hippocampal apoptosis in sepsis

scientific article published on 11 October 2012

Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis

scientific article

Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis.

scientific article

Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes.

scientific article

Combined effect of non-bacteriolytic antibiotic and inhibition of matrix metalloproteinases prevents brain injury and preserves learning, memory and hearing function in experimental paediatric pneumococcal meningitis

scientific article published on 21 August 2018

Combining Ceftriaxone with Doxycycline and Daptomycin Reduces Mortality, Neuroinflammation, Brain Damage, and Hearing Loss in Infant Rat Pneumococcal Meningitis

scientific article published on 24 June 2019

Comparison of Four Commercial IgG-Enzyme-Linked Immunosorbent Assays for the Detection of Tick-Borne Encephalitis Virus Antibodies

scientific article published on 04 December 2018

Correction for Liechti et al., Matrix Metalloproteinase Inhibition Lowers Mortality and Brain Injury in Experimental Pneumococcal Meningitis.

scientific article published in October 2014

Correlation of serum and urinary matrix metalloproteases/tissue inhibitors of metalloproteases with subclinical allograft fibrosis in renal transplantation

scientific article published on 27 November 2013

Current concepts in the pathogenesis of meningitis caused by Streptococcus pneumoniae.

scientific article

DNA repair protein APE1 is involved in host response during pneumococcal meningitis and its expression can be modulated by vitamin B6.

scientific article published on 12 December 2017

Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice

scientific article (publication date: May 2015)

Detrimental effect of nitric oxide inhibition in experimental bacterial meningitis

scientific article published on 01 April 1996

Dexamethasone aggravates hippocampal apoptosis and learning deficiency in pneumococcal meningitis in infant rats

scientific article published on 4 June 2003

Differential effect of p47phox and gp91phox deficiency on the course of Pneumococcal Meningitis

scientific article

Differential effects of interferon-gamma and tumor necrosis factor-alpha on Toxoplasma gondii proliferation in organotypic rat brain slice cultures

scientific article published in April 2005

Distribution of human immunodeficiency virus (HIV) in the CNS of children with severe HIV encephalomyelopathy

scientific article published in January 1992

Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model?

scientific article published on 15 January 2015

Doxycycline reduces mortality and injury to the brain and cochlea in experimental pneumococcal meningitis

scientific article

Dysphagia in elderly women: consider tetanus

scientific article published in February 2006

ESCMID guideline: diagnosis and treatment of acute bacterial meningitis.

scientific article published on 7 April 2016

Effect of interferon-beta and atorvastatin on Th1/Th2 cytokines in multiple sclerosis

scientific article published on 20 April 2008

Effect of the NMDA-receptor antagonist dextromethorphan in infant rat pneumococcal meningitis

scientific article published in January 2008

Effects of Clinically Used Antioxidants in Experimental Pneumococcal Meningitis

scientific article published on 06 July 2000

Effects of Toll-like receptor 2 agonist Pam(3)CysSK(4) on inflammation and brain damage in experimental pneumococcal meningitis

scientific article published on 13 November 2008

Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins

scientific article published on 23 February 2017

Endogenous and synthetic MMP inhibitors in CNS physiopathology

scientific article

Endothelin inhibition improves cerebral blood flow and is neuroprotective in pneumococcal meningitis

scientific article published on 01 March 2000

Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age

scientific article published on 06 July 2020

Epidemiology of Human Adenoviruses: A 20-Year Retrospective Observational Study in Hospitalized Patients in Bern, Switzerland

scientific article published on 05 April 2020

Essential role of choline for pneumococcal virulence in an experimental model of meningitis

scientific article published on 5 March 2008

Evaluation of antivirals against tick-borne encephalitis virus in organotypic brain slices of rat cerebellum

scientific article published in PLoS ONE

Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis

scientific article published on 07 October 2020

Expression and Function of Psoriasin (S100A7) and Koebnerisin (S100A15) in the Brain ⬇️

scientific article published on March 11, 2013

Fatal bronchopneumonia caused by skunk adenovirus 1 in an African pygmy hedgehog

scientific article published on 26 November 2018

Flu-related neurological complications: incidence and risk factors in children

scientific article published on 28 August 2007

Foreign peptide triggers boost in pneumococcal metabolism and growth.

scientific article published on 27 March 2018

Gelatinase B [matrix metalloproteinase (MMP)-9] and collagenases (MMP-8/-13) are upregulated in cerebrospinal fluid during aseptic and bacterial meningitis in children

scientific article published on 01 June 2006

Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis

article

Gene expression in cortex and hippocampus during acute pneumococcal meningitis

scientific article

Genetic polymorphisms associated with the inflammatory response in bacterial meningitis.

scientific article published on 28 August 2015

Grafted Neural Progenitor Cells Persist in the Injured Site and Differentiate Neuronally in a Rodent Model of Cardiac Arrest-Induced Global Brain Ischemia

scientific article published on 19 February 2020

Grafted neuronal precursor cells differentiate and integrate in injured hippocampus in experimental pneumococcal meningitis

scientific article

Herpes-simplex virus encephalitis is characterized by an early MMP-9 increase and collagen type IV degradation

scientific article published on 14 November 2006

Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis

scientific article published in June 2003

Improving the quality and workflow of bacterial genome sequencing and analysis: paving the way for a Switzerland-wide molecular epidemiological surveillance platform

scientific article published on 15 December 2018

In Vitro Activity of the Novel Antimicrobial Peptide Dendrimer G3KL against Multidrug-Resistant Acinetobacter baumannii and Pseudomonas aeruginosa

scientific article

In bacterial meningitis cortical brain damage is associated with changes in parenchymal MMP-9/TIMP-1 ratio and increased collagen type IV degradation

scientific article published on 27 October 2005

In pneumococcal meningitis a novel water-soluble inhibitor of matrix metalloproteinases and TNF-alpha converting enzyme attenuates seizures and injury of the cerebral cortex

scientific article

In search of strategies for preventing brain damage as a sequela of bacterial meningitis

scientific article published in June 2000

In vitro induction of lymph node cell proliferation by mouse bone marrow dendritic cells following stimulation with different Echinococcus multilocularis antigens

scientific article published on 01 June 2011

Increase in hippocampal water diffusion and volume during experimental pneumococcal meningitis is aggravated by bacteremia

scientific article

Inducible nitric oxide synthase and nitrotyrosine in listeric encephalitis: a cross-species study in ruminants

scientific article

Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis.

scientific article published in March 1998

Induction of haem oxygenase-1 causes cortical non-haem iron increase in experimental pneumococcal meningitis: evidence that concomitant ferritin up-regulation prevents iron-induced oxidative damage

scientific article published on 20 November 2006

Infection of organotypic slice cultures from rat central nervous tissue with Neospora caninum: an alternative approach to study host-parasite interactions

scientific article published on May 2002

Inflammasome-dependent IFN-γ drives pathogenesis in Streptococcus pneumoniae meningitis.

scientific article published on 15 October 2012

Inflammatory markers in pediatric stroke: An attempt to better understanding the pathophysiology.

scientific article

Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis.

scientific article published on 11 January 2016

Inhibition of matrix metalloproteinases and tumour necrosis factor alpha converting enzyme as adjuvant therapy in pneumococcal meningitis

scientific article published in September 2001

Inhibition of matrix metalloproteinases attenuates brain damage in experimental meningococcal meningitis

scientific article

Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis

scientific article published on November 2010

Intracisternal application of endotoxin enhances the susceptibility to subsequent hypoxic-ischemic brain damage in neonatal rats.

scientific article published on 5 March 2003

Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An in Vivo Study With an Experimental Model of Foreign-Body Infection.

scientific article published on 15 May 2018

JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis

scientific article published on 18 July 2008

Levels of matrix metalloproteinase-9 within cerebrospinal fluid in a rabbit model of coccidioidal meningitis and vasculitis

scientific article published on November 2002

Limited Correlation of Shotgun Metagenomics Following Host Depletion and Routine Diagnostics for Viruses and Bacteria in Low Concentrated Surrogate and Clinical Samples

scientific article published on 23 October 2018

Limited efficacy of adjuvant therapy with dexamethasone in preventing hearing loss due to experimental pneumococcal meningitis in the infant rat.

scientific article

MMPs and ADAMs in neurological infectious diseases and multiple sclerosis

scientific article published on 06 June 2019

Managing atypical and typical herpetic central nervous system infections: results of a multinational study.

scientific article published on 13 April 2016

Marked elevation in cortical urate and xanthine oxidoreductase activity in experimental bacterial meningitis

scientific article

Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood-brain barrier damage and neurological sequelae

scientific article published on 14 July 2000

Matrix metalloproteinase inhibition lowers mortality and brain injury in experimental pneumococcal meningitis

scientific article published on 03 February 2014

Matrix metalloproteinase-9 in pneumococcal meningitis: activation via an oxidative pathway

scientific article published on 15 April 2003

Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis.

scientific article

Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis

scientific article published on 01 October 2001

Meningitis (I)--differential diagnosis; aseptic and chronic meningitis

scientific article published on November 1999

Meningitis in Neonates: Bench to Bedside ⬇️

scientific article published on September 1, 2010

Meningokokkeninfektion: Zwei Fälle zur Breite des klinischen Spektrums

scientific article published on 01 October 2006

Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis

scientific article published on 27 July 2019

Microglial Cells Prevent Hemorrhage in Neonatal Focal Arterial Stroke.

scientific article

Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure.

scientific article

Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression.

scientific article published on 30 April 2015

Neospora caninumand bone marrow-derived dendritic cells: parasite survival, proliferation, and induction of cytokine expression

scientific article published on 01 July 2009

Neuropathology and pathogenesis of HIV encephalopathies

scientific article published on January 1, 1992

Neuroprotection with the P53-Inhibitor Pifithrin-μ After Cardiac Arrest in a Rodent Model.

scientific article published on 30 May 2017

Neuroprotective effect of excitatory amino acid antagonist kynurenic acid in experimental bacterial meningitis.

scientific article published in January 1996

Nitric oxide is protective in listeric meningoencephalitis of rats

scientific article

Nocardia cyriacigeorgici: First report of invasive human infection

scientific article

Nocardial Brain Abscess: Observation of Treatment Strategies and Outcome in Switzerland from 1992 to 1999

article

Novel and preclinical treatment strategies in pneumococcal meningitis.

scientific article published in November 2017

Organotypic slice cultures from rat brain tissue: a new approach for Naegleria fowleri CNS infection in vitro

article

Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment

scientific article

PCR identification of HIV-1 DNA sequences in brain tissue of patients with AIDS encephalopathy

scientific article

Performance of adjunctive therapy in bacterial meningitis depends on circumstances

scientific article published on December 2013

Phage lytic enzyme Cpl-1 for antibacterial therapy in experimental pneumococcal meningitis

scientific article published in June 2008

Pneumococcal meningitis induces apoptosis in recently postmitotic immature neurons in the dentate gyrus of neonatal rats

scientific article published in January 2007

Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia

scientific article published on 18 May 2019

Predictive Value of Cerebrospinal Fluid (CSF) Lactate Level Versus CSF/Blood Glucose Ratio for the Diagnosis of Bacterial Meningitis Following Neurosurgery

scientific article published on 01 July 1999

Prevalence of tick-borne pathogens in questing Ixodes ricinus ticks in urban and suburban areas of Switzerland

scientific article published on 9 November 2017

Pulmonary nocardiosis in Western Europe-Clinical evaluation of 43 patients and population-based estimates of hospitalization rates

scientific article published on 15 January 2019

Rapid and Cost-Efficient Enterovirus Genotyping from Clinical Samples Using Flongle Flow Cells

scientific article published on 29 August 2019

Rapid diagnosis of experimental meningitis by bacterial heat production in cerebrospinal fluid

scientific article

RecNcMIC3-1-R is a microneme- and rhoptry-based chimeric antigen that protects against acute neosporosis and limits cerebral parasite load in the mouse model for Neospora caninum infection

scientific article published on 23 July 2011

Repetitive transcranial magnetic stimulation activates glial cells and inhibits neurogenesis after pneumococcal meningitis

scientific article published on 11 September 2020

Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis.

scientific article

Role of glial cells in the functional expression of LL-37/rat cathelin-related antimicrobial peptide in meningitis

scientific article published in November 2008

Ruminant organotypic brain-slice cultures as a model for the investigation of CNS listeriosis

scientific article published in August 2012

SNPs in DNA repair genes associated to meningitis and host immune response

article

Severe hepatotoxicity following ingestion of Herbalife nutritional supplements contaminated with Bacillus subtilis.

scientific article

SiRNA inhibits replication of Langat virus, a member of the tick-borne encephalitis virus complex in organotypic rat brain slices.

scientific article

Strategies to prevent neuronal damage in paediatric bacterial meningitis.

scientific article

Streptococcus pneumoniae capsule determines disease severity in experimental pneumococcal meningitis.

scientific article published on March 2016

Streptococcus pneumoniae-induced ototoxicity in organ of Corti explant cultures.

scientific article

Temporal expression of inflammatory mediators in brain basilar artery vasculitis and cerebrospinal fluid of rabbits with coccidioidal meningitis

scientific article published in March 2006

Testing bioresorbable stent feasibility in a rat aneurysm model

scientific article published on 09 March 2019

The Impact of Pneumococcal Conjugate Vaccine (PCV) Coverage Heterogeneities on the Changing Epidemiology of Invasive Pneumococcal Disease in Switzerland, 2005–2019

scientific article published in 2021

The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis.

scientific article published on July 2016

The antidepressant fluoxetine protects the hippocampus from brain damage in experimental pneumococcal meningitis

scientific article published on April 2015

The causative pathogen determines the inflammatory profile in cerebrospinal fluid and outcome in patients with bacterial meningitis

scientific article published on 20 June 2013

The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis.

scientific article

The free radical scavenger alpha-phenyl-tert-butyl nitrone aggravates hippocampal apoptosis and learning deficits in experimental pneumococcal meningitis

scientific article published on 8 December 2000

The kynurenine pathway is involved in bacterial meningitis

scientific article

The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis.

scientific article

The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis

scientific article

Therapy of community-acquired acute bacterial meningitis: the clock is running.

scientific article

Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation.

scientific article published on 16 August 2002

Tumor necrosis factor-alpha contributes to apoptosis in hippocampal neurons during experimental group B streptococcal meningitis

scientific article published in September 1997

Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model

scientific article

Vaccination with recombinant NcROP2 combined with recombinant NcMIC1 and NcMIC3 reduces cerebral infection and vertical transmission in mice experimentally infected with Neospora caninum tachyzoites

scientific article published on 15 May 2009

Vaccination with the recombinant chimeric antigen recNcMIC3-1-R induces a non-protective Th2-type immune response in the pregnant mouse model for N. caninum infection

article

Virulence Traits of a Serogroup C Meningococcus and Isogenic cssA Mutant, Defective in Surface-Exposed Sialic Acid, in a Murine Model of Meningitis

scientific article published on 25 March 2019

Vitamin B6 reduces hippocampal apoptosis in experimental pneumococcal meningitis.

scientific article

Was durch einen Visusverlust ans Licht kommt

scientific article published on 01 March 2012

Whole-Genome Sequencing of Human Enteroviruses from Clinical Samples by Nanopore Direct RNA Sequencing

scientific article published on 31 July 2020

[A case from practice (305). Recurrent erysipelas--tinea pedis et unginum--chronic venous insufficiency]

scientific article published on 01 September 1994

[Drug-induced Stevens-Johnson syndrome in a patient with AIDS]

scientific article published on 01 August 1993

[The role of nitric oxide in Listeria encephalitis of ruminants and in rats intracisternally infected with Listeria monocytogenes]

article

[What is your diagnosis? Basal meningitis and rhombencephalitis. Blood culture positive for Listeria monocytogenes]

scientific article published on 01 May 2001

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