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List of works by Denis Grandgirard

0353. Do the noble gases helium and argon exert neuroprotective effects in a rodent cardiac arrest model?

scientific article published on 26 September 2014

0356. Effect of the neuroprotective p53-inhibitor pifithrin-µ in a rodent cardiac arrest model.

scientific article

A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model.

scientific article published on 4 April 2016

A tick-borne encephalitis model in infant rats infected with langat virus

scientific article published on December 2014

Adjunctive daptomycin attenuates brain damage and hearing loss more efficiently than rifampin in infant rat pneumococcal meningitis.

scientific article

Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitis

scientific article (publication date: 2011)

Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis

scientific article

Alphaviral cytotoxicity and its implication in vector development.

scientific article

Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2.

scientific article published on August 1998

An improved simple rat model for global cerebral ischaemia by induced cardiac arrest.

scientific article published on 7 September 2015

An infant mouse model of brain damage in pneumococcal meningitis

scientific article published on 16 October 2007

Apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited

scientific article

Atorvastatin does not alter serum levels of sCD95 and sCD95L in multiple sclerosis

scientific article

Attenuation of cerebrospinal fluid inflammation by the nonbacteriolytic antibiotic daptomycin versus that by ceftriaxone in experimental pneumococcal meningitis

scientific article

Bacterial meningitis impairs hippocampal neurogenesis

scientific article

Bacterial meningitis: insights into pathogenesis and evaluation of new treatment options: a perspective from experimental studies

scientific article published on 29 June 2015

CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells

scientific article published on 08 June 2022

Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis.

scientific article published on 12 February 2003

Caspase-3 mediates in part hippocampal apoptosis in sepsis

scientific article published on 11 October 2012

Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis.

scientific article

Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes.

scientific article

Combined effect of non-bacteriolytic antibiotic and inhibition of matrix metalloproteinases prevents brain injury and preserves learning, memory and hearing function in experimental paediatric pneumococcal meningitis

scientific article published on 21 August 2018

Combining Ceftriaxone with Doxycycline and Daptomycin Reduces Mortality, Neuroinflammation, Brain Damage, and Hearing Loss in Infant Rat Pneumococcal Meningitis

scientific article published on 24 June 2019

Correction for Liechti et al., Matrix Metalloproteinase Inhibition Lowers Mortality and Brain Injury in Experimental Pneumococcal Meningitis.

scientific article published in October 2014

Correlation of serum and urinary matrix metalloproteases/tissue inhibitors of metalloproteases with subclinical allograft fibrosis in renal transplantation

scientific article published on 27 November 2013

Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice

scientific article (publication date: May 2015)

Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model?

scientific article published on 15 January 2015

Effect of interferon-beta and atorvastatin on Th1/Th2 cytokines in multiple sclerosis

scientific article published on 20 April 2008

Effects of Toll-like receptor 2 agonist Pam(3)CysSK(4) on inflammation and brain damage in experimental pneumococcal meningitis

scientific article published on 13 November 2008

Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins

scientific article published on 23 February 2017

Endogenous and synthetic MMP inhibitors in CNS physiopathology

scientific article

Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age

scientific article published on 06 July 2020

Essential role of choline for pneumococcal virulence in an experimental model of meningitis

scientific article published on 5 March 2008

Fatal Outcome of European Tick-borne Encephalitis after Vaccine Failure

scientific article published on 03 April 2017

Foreign peptide triggers boost in pneumococcal metabolism and growth.

scientific article published on 27 March 2018

In vitro induction of lymph node cell proliferation by mouse bone marrow dendritic cells following stimulation with different Echinococcus multilocularis antigens

scientific article published on 01 June 2011

Inflammatory markers in pediatric stroke: An attempt to better understanding the pathophysiology.

scientific article

Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis.

scientific article published on 11 January 2016

Inhibition of matrix metalloproteinases attenuates brain damage in experimental meningococcal meningitis

scientific article

Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An in Vivo Study With an Experimental Model of Foreign-Body Infection.

scientific article published on 15 May 2018

Matrix metalloproteinase inhibition lowers mortality and brain injury in experimental pneumococcal meningitis

scientific article published on 03 February 2014

Meningitis in Neonates: Bench to Bedside ⬇️

scientific article published on September 1, 2010

Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure.

scientific article

Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression.

scientific article published on 30 April 2015

Neospora caninumand bone marrow-derived dendritic cells: parasite survival, proliferation, and induction of cytokine expression

scientific article published on 01 July 2009

Neuroprotection with the P53-Inhibitor Pifithrin-μ After Cardiac Arrest in a Rodent Model.

scientific article published on 30 May 2017

Novel and preclinical treatment strategies in pneumococcal meningitis.

scientific article published in November 2017

Phage lytic enzyme Cpl-1 for antibacterial therapy in experimental pneumococcal meningitis

scientific article published in June 2008

Pneumococcal meningitis induces apoptosis in recently postmitotic immature neurons in the dentate gyrus of neonatal rats

scientific article published in January 2007

Prevention of brain injury by the nonbacteriolytic antibiotic daptomycin in experimental pneumococcal meningitis

scientific article (publication date: June 2007)

RecNcMIC3-1-R is a microneme- and rhoptry-based chimeric antigen that protects against acute neosporosis and limits cerebral parasite load in the mouse model for Neospora caninum infection

scientific article published on 23 July 2011

Repetitive transcranial magnetic stimulation activates glial cells and inhibits neurogenesis after pneumococcal meningitis

scientific article published on 11 September 2020

Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis.

scientific article

SiRNA inhibits replication of Langat virus, a member of the tick-borne encephalitis virus complex in organotypic rat brain slices.

scientific article

Strategies to prevent neuronal damage in paediatric bacterial meningitis.

scientific article

Streptococcus pneumoniae capsule determines disease severity in experimental pneumococcal meningitis.

scientific article published on March 2016

Streptococcus pneumoniae-induced ototoxicity in organ of Corti explant cultures.

scientific article

The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis.

scientific article published on July 2016

The antidepressant fluoxetine protects the hippocampus from brain damage in experimental pneumococcal meningitis

scientific article published on April 2015

The causative pathogen determines the inflammatory profile in cerebrospinal fluid and outcome in patients with bacterial meningitis

scientific article published on 20 June 2013

The kynurenine pathway is involved in bacterial meningitis

scientific article

The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis.

scientific article

The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis

scientific article

Therapeutic effects of bacteriophage Cpl-1 lysin against Streptococcus pneumoniae endocarditis in rats

scientific article

Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model

scientific article

Vaccination with recombinant NcROP2 combined with recombinant NcMIC1 and NcMIC3 reduces cerebral infection and vertical transmission in mice experimentally infected with Neospora caninum tachyzoites

scientific article published on 15 May 2009

Vaccination with the recombinant chimeric antigen recNcMIC3-1-R induces a non-protective Th2-type immune response in the pregnant mouse model for N. caninum infection

article

Virulence Traits of a Serogroup C Meningococcus and Isogenic cssA Mutant, Defective in Surface-Exposed Sialic Acid, in a Murine Model of Meningitis

scientific article published on 25 March 2019

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