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List of works by Henrik Gréen

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The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c.

scientific article published in December 2011
Pharmacogenetic studies of Paclitaxel in the treatment of ovarian cancer

scientific article published on 16 December 2008
Impact of CYP2C8*3 on paclitaxel clearance: a population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer.

scientific article published on 6 April 2010
ABCB1 G1199A polymorphism and ovarian cancer response to paclitaxel

scientific article published in June 2008
Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy.

scientific article published on 20 June 2012
Retrospective study of the impact of pharmacogenetic variants on paclitaxel toxicity and survival in patients with ovarian cancer

scientific article published on 16 February 2011
Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy

scientific journal article
CYP3A activity influences imatinib response in patients with chronic myeloid leukemia: a pilot study on in vivo CYP3A activity

scientific article published in April 2010
Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5'-nucleotidase

scientific article published on 9 September 2013
Association of ABCB1 polymorphisms with survival and in vitro cytotoxicty in de novo acute myeloid leukemia with normal karyotype

scientific article published on 12 October 2010
Impact of ABCB1 variants on neutrophil depression: a pharmacogenomic study of paclitaxel in 92 women with ovarian cancer

scientific article
Identification of AB‐FUBINACA metabolites in authentic urine samples suitable as urinary markers of drug intake using liquid chromatography quadrupole tandem time of flight mass spectrometry

scientific article published on November 11, 2015
Influence of Cremophor EL and genetic polymorphisms on the pharmacokinetics of paclitaxel and its metabolites using a mechanism-based model

scientific article published on 5 November 2010
Pharmacogenetics, plasma concentrations, clinical signs and EEG during propofol treatment

scientific article published on 19 July 2014
GWAS-based association between RWDD3 and TECTA variants and paclitaxel induced neuropathy could not be confirmed in Scandinavian ovarian cancer patients

scientific article published on 9 August 2012
Identification of AKB-48 and 5F-AKB-48 Metabolites in Authentic Human Urine Samples Using Human Liver Microsomes and Time of Flight Mass Spectrometry

scientific article published on May 7, 2015
Measurement of paclitaxel and its metabolites in human plasma using liquid chromatography/ion trap mass spectrometry with a sonic spray ionization interface

scientific article published in January 2006
Effects of nicotine, its metabolites and tobacco extracts on human platelet function in vitro

scientific article published on 11 January 2013
Single-nucleotide polymorphisms of ABCG2 increase the efficacy of tyrosine kinase inhibitors in the K562 chronic myeloid leukemia cell line

scientific article published on January 2014
Melanin inhibits cytotoxic effects of doxorubicin and daunorubicin in MOLT 4 cells

scientific article published on August 2003
Impact of CYP3A5*3 and CYP2C8-HapC on paclitaxel/carboplatin-induced myelosuppression in patients with ovarian cancer.

scientific article published on 23 June 2011
The pan-ErbB receptor tyrosine kinase inhibitor canertinib promotes apoptosis of malignant melanoma in vitro and displays anti-tumor activity in vivo

scientific article published in October 2011
Correlations between metabolism and structural elements of the alicyclic fentanyl analogs cyclopropyl fentanyl, cyclobutyl fentanyl, cyclopentyl fentanyl, cyclohexyl fentanyl and 2,2,3,3-tetramethylcyclopropyl fentanyl studied by human hepatocytes an

scientific article published on 25 October 2018
Histone H1 interphase phosphorylation becomes largely established in G1 or early S phase and differs in G1 between T-lymphoblastoid cells and normal T cells

scientific article published on 05 August 2011
Irreversible pan-ERBB inhibitor canertinib elicits anti-leukaemic effects and induces the regression of FLT3-ITD transformed cells in mice

scientific article published on 16 August 2011
ABCB1 haplotypes do not influence transport or efficacy of tyrosine kinase inhibitors in vitro

scientific article published on 20 August 2013
Assessment of whole genome amplification for sequence capture and massively parallel sequencing

scientific article published on 07 January 2014
Spontaneous reversal of p-glycoprotein expression in multidrug resistant cell lines

scientific article published on December 2003
Pegylated liposomal doxorubicin as first-line monotherapy in elderly women with locally advanced or metastatic breast cancer: novel treatment predictive factors identified

scientific article published on 31 August 2011
A validated liquid chromatography tandem mass spectrometry method for quantification of erlotinib, OSI-420 and didesmethyl erlotinib and semi-quantification of erlotinib metabolites in human plasma

scientific article published on December 25, 2014
Identification of candidate SNPs for drug induced toxicity from differentially expressed genes in associated tissues

scientific article
Pharmacogenomics of importance for paclitaxel chemotherapy

scientific article published in June 2008
ABCB1 gene polymorphisms are associated with suicide in forensic autopsies

scientific article published in September 2013
beta-Tubulin mutations in ovarian cancer using single strand conformation analysis-risk of false positive results from paraffin embedded tissues

scientific article published on 5 July 2005
Comparison of two types of population pharmacokinetic model structures of paclitaxel

scientific article
The pan-ErbB tyrosine kinase inhibitor canertinib induces caspase-mediated cell death in human T-cell leukemia (Jurkat) cells

scientific article published on 6 June 2011
Semi-physiologically based pharmacokinetic modeling of paclitaxel metabolism and in silico-based study of the dynamic sensitivities in pathway kinetics

scientific article published on 15 August 2012
Novel rapid liquid chromatography tandem masspectrometry method for vemurafenib and metabolites in human plasma, including metabolite concentrations at steady state

scientific article published on 18 December 2015
Validation of whole genome amplification for analysis of the p53 tumor suppressor gene in limited amounts of tumor samples

scientific article published on 27 July 2012
Biotransformation of the New Synthetic Cannabinoid with an Alkene, MDMB-4en-PINACA, by Human Hepatocytes, Human Liver Microsomes, and Human Urine and Blood

scientific article published on 17 December 2019
ABCB1 Variation Affects Myelosuppression, Progression-free Survival and Overall Survival in Paclitaxel/Carboplatin-treated Ovarian Cancer Patients

scientific article published on 19 April 2018
Biomarkers and Proteomics in Sarcomeric Hypertrophic Cardiomyopathy in the Young—FGF-21 Highly Associated with Overt Disease

scientific article published in 2024
The influence of ABCG2 polymorphism on erlotinib efflux in the K562 cell line

scientific article published on 01 April 2020
Single-Cell RNA Sequencing of Hematopoietic Stem and Progenitor Cells Treated with Gemcitabine and Carboplatin

scientific article published on 14 May 2020
A validated and rapid high-performance liquid chromatography method for the quantification of conversion of radio-labelled sex steroids

scientific article published on December 1, 2010
Microtubule-Targeting Drugs and Personalization of Cancer Treatment

scientific article published on April 1, 2011
Whole-genome sequencing of human remains to enable genealogy DNA database searches - A case report

scientific article published on 17 January 2020
Hereditary Hypertrophic Cardiomyopathy in Children and Young Adults-The Value of Reevaluating and Expanding Gene Panel Analyses

scientific article published on 08 December 2020
Metabolism of MMB022 and identification of dihydrodiol formation in vitro using synthesised standards

scientific article published on 01 July 2020
Activation of the μ-opioid receptor by alicyclic fentanyls: changes from high potency full agonists to low potency partial agonists with increasing alicyclic substructure

scientific article published on 04 August 2020

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