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List of works by Maria Alexandra Brito

5-(Hydroxyphenyl)-γ-Valerolactone-Sulfate, a Key Microbial Metabolite of Flavan-3-ols, Is Able to Reach the Brain: Evidence from Different in Silico, In Vitro and In Vivo Experimental Models

scientific article published on 05 November 2019

A link between hyperbilirubinemia, oxidative stress and injury to neocortical synaptosomes

scientific article published in November 2004

A look at tricellulin and its role in tight junction formation and maintenance

scientific article published on 24 August 2011

Alterations of erythrocyte morphology and lipid composition by hyperbilirubinemia

article

Apoptosis and impairment of neurite network by short exposure of immature rat cortical neurons to unconjugated bilirubin increase with cell differentiation and are additionally enhanced by an inflammatory stimulus

scientific article published in May 2007

Aquaporin-5: from structure to function and dysfunction in cancer.

scientific article published on 2 February 2016

Assessment of bilirubin toxicity to erythrocytes. Implication in neonatal jaundice management

article

Astrocyte reactivity to unconjugated bilirubin requires TNF-α and IL-1β receptor signaling pathways

scientific journal article

Bilirubin directly disrupts membrane lipid polarity and fluidity, protein order, and redox status in rat mitochondria.

scientific article published in March 2002

Bilirubin induces loss of membrane lipids and exposure of phosphatidylserine in human erythrocytes

scientific article published in January 2002

Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid

scientific article published on 19 November 2007

Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid.

scientific article published on 10 October 2009

Bilirubin toxicity to human erythrocytes: a review

scientific article published on 17 June 2006

Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation state

scientific article

Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cells

scientific article published in November 2005

Biological risks for neurological abnormalities associated with hyperbilirubinemia.

scientific article published on February 2009

Blood-brain barrier and bilirubin: clinical aspects and experimental data

scientific article

Brain metastasization of breast cancer.

scientific article published on 21 March 2017

Cellular response of the blood-brain barrier to injury: Potential biomarkers and therapeutic targets for brain regeneration

scientific article published on 17 March 2016

Cerebellar axon/myelin loss, angiogenic sprouting, and neuronal increase of vascular endothelial growth factor in a preterm infant with kernicterus

scientific article published on 21 December 2011

Corrigendum

scholarly article published in Journal of Cerebral Blood Flow & Metabolism

Corrigendum to “A look at tricellulin and its role in tight junction formation and maintenance” [Eur. J. Cell Biol. 90 (2011) 787–796]

scholarly article published in European Journal of Cell Biology

Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS.

scientific article

Deconstructing breast cancer cell biology and the mechanisms of multidrug resistance.

scientific article

Differential expression of aquaporin-3 and aquaporin-5 in pancreatic ductal adenocarcinoma.

scientific article

Dissecting the Contribution of Vascular Alterations and Aging to Alzheimer's Disease

scientific article published on 05 July 2015

Downregulation of circulating miR 802-5p and miR 194-5p and upregulation of brain MEF2C along breast cancer brain metastasization

scientific article published on 05 February 2020

Effect of acidosis on bilirubin-induced toxicity to human erythrocytes

scientific article published on May 2003

Effect of bilirubin on toxicity induced by trifluoperazine, dibucaine and praziquantel to erythrocytes

scientific article published in July 2001

Effects of bilirubin molecular species on membrane dynamic properties of human erythrocyte membranes: a spin label electron paramagnetic resonance spectroscopy study

scientific article published in March 2001

Elevated levels of bilirubin and long-term exposure impair human brain microvascular endothelial cell integrity

scientific article published on May 2011

Endothelial progenitor cells in multiple myeloma neovascularization: a brick to the wall

scientific article published on 24 August 2017

Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier

scientific article

Evidence of tricellulin expression by immune cells, particularly microglia

article

Exposure to lipopolysaccharide and/or unconjugated bilirubin impair the integrity and function of brain microvascular endothelial cells

scientific article

Extracellular matrix markers for disease progression and follow-up of therapies in familial amyloid polyneuropathy V30M TTR-related

scientific article published on January 2008

Features of bilirubin-induced reactive microglia: from phagocytosis to inflammation

scientific article

Glio-vascular changes during ageing in wild-type and Alzheimer's disease-like APP/PS1 mice.

scientific article

Glycoursodeoxycholic Acid and Interleukin-10 Modulate the Reactivity of Rat Cortical Astrocytes to Unconjugated Bilirubin

scientific article published on 01 September 2007

Hydrophilic bile acids protect human blood-brain barrier endothelial cells from disruption by unconjugated bilirubin: an in vitro study

scientific article

Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubin

scientific article published on 10 February 2006

Influence of hypoxia and ischemia preconditioning on bilirubin damage to astrocytes

scientific article published on 24 February 2007

Inhibition of Glutamate Uptake by Unconjugated Bilirubin in Cultured Cortical Rat Astrocytes: Role of Concentration and pH

scientific article published on 01 November 1999

LDL-Cholesterol Increases the Transcytosis of Molecules through Endothelial Monolayers

scientific article

Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches ⬇️

scientific article published on May 26, 2010

MAPKs are key players in mediating cytokine release and cell death induced by unconjugated bilirubin in cultured rat cortical astrocytes

scientific article

Membrane effects of trifluoperazine, dibucaine and praziquantel on human erythrocytes

scientific article published in May 2000

Membrane structural changes support the involvement of mitochondria in the bile salt-induced apoptosis of rat hepatocytes.

scientific article published in November 2002

MicroRNAs and Extracellular Vesicles as Distinctive Biomarkers of Precocious and Advanced Stages of Breast Cancer Brain Metastases Development ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

N-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicity

scientific article

Neurovascular unit: a focus on pericytes

scientific article published on 28 February 2012

New autopsy findings in different brain regions of a preterm neonate with kernicterus: neurovascular alterations and up-regulation of efflux transporters

scientific article published on 15 October 2013

Polyphenols journey through blood-brain barrier towards neuronal protection.

scientific article published on 13 September 2017

Potential for brain accessibility and analysis of stability of selected flavonoids in relation to neuroprotection in vitro.

scientific article

Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin

scientific article published on 16 March 2011

Response to the Letter to the Editor by Mamdouha Ahdab-Barmada and Jon F. Watchko

scientific article published on 17 February 2014

Role of multidrug resistance-associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin

scientific journal article

Selective vulnerability of rat brain regions to unconjugated bilirubin

scientific article published on 25 June 2011

Synthesis and friedländer reactions of 5-amino-4-cyano-1,3-oxazoles

Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects

scientific article published on 29 April 2015

The TNF-α/NF-κB signaling pathway has a key role in methamphetamine-induced blood-brain barrier dysfunction

scientific article published on 22 April 2015

The choroid plexus in health and in disease: dialogues into and out of the brain

scientific article

Thioredoxin, glutathione and related molecules in tumors of the nervous system

scientific article published on 31 January 2019

Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining

scientific article

Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

article

Tricellulin expression in brain endothelial and neural cells

scientific article published on 19 December 2012

Unconjugated bilirubin activates and damages microglia

scientific article

Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells

scientific article published on 01 August 2007

miRNAs in Health and Disease: A Focus on the Breast Cancer Metastatic Cascade towards the Brain

scientific article published on 28 July 2020

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