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List of works by Irene Maeve Rea

A whole blood method for measurement of intracellular TNF-alpha, IFN-gamma and IL-2 expression in stimulated CD3+ lymphocytes: differences between young and elderly subjects

scientific article published in January 2002

ABCB1 (MDR1) rs1045642 is associated with increased overall survival in plasma cell myeloma.

scientific article published in April 2009

Age-related alterations in basal expression and in vitro, tumour necrosis factor alpha mediated, upregulation of CD11b

scientific article

Age-related changes in non-receptor dependent generation of reactive oxygen species from phagocytes of healthy adults

scientific article published on 01 March 1997

Age-related reference intervals for lymphocyte subsets in whole blood of healthy individuals

scientific article published on 01 April 1999

Ageing in the 21st Century. Where to and how will we get there? Report on the 10th congress of the international association of biomedical gerontology, the geriatrician's view

article

Altered methylation levels in elderly acute myeloid leukaemia patients compared to elderly well individuals.

scientific article

Apolipoprotein E alleles in nonagenarian subjects in the Belfast Elderly Longitudinal Free-living Ageing Study (BELFAST)

scientific article published on 01 September 2001

BELFAST centenarians: a case of optimised cardiovascular risk?

scientific article published in January 2010

BELFAST nonagenarians: nature or nurture? Immunological, cardiovascular and genetic factors

scientific article

Blood pressure and TNF-α act synergistically to increase leucocyte CD11b adhesion molecule expression in the BELFAST study: implications for better blood pressure control in ageing ⬇️

scientific article published on November 16, 2011

CD69, CD25, and HLA-DR activation antigen expression on CD3+ lymphocytes and relationship to serum TNF-α, IFN-γ, and sIL-2R levels in aging

scientific article published on 01 January 1999

Changes in natural killer cells, the CD57CD8 subset, and related cytokines in healthy aging

scientific article published on 01 January 1998

Community-living nonagenarians in Northern Ireland have lower plasma homocysteine but similar methylenetetrahydrofolate reductase thermolabile genotype prevalence compared to 70–89-year-old subjects

scientific article published on 01 March 2000

Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death.

scientific article

Flow cytometry analysis of platelet P-selectin expression in whole blood - methodological considerations

scientific article published on 01 December 2000

Functional promoter region polymorphism of the proinflammatory chemokine IL-8 gene associates with Parkinson's disease in the Irish

scientific article published in April 2004

Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).

scientific article published on April 2007

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

scientific article published on 06 February 2013

HLA haplotypes and TNF polymorphism do not associate with longevity in the Irish

scientific article published on 01 April 2003

Hypothetical soluble KIR2DS4 natural killer cell receptor molecule does not associate with successful ageing in the Irish

scientific article published in May 2004

Increased frequency of the 2437T allele of the heat shock protein 70-Hom gene in an aged Irish population.

scientific article

Interleukin-6-gene C/G 174 polymorphism in nonagenarian and octogenarian subjects in the BELFAST study. Reciprocal effects on IL-6, soluble IL-6 receptor and for IL-10 in serum and monocyte supernatants

article

Investigation of KIR diversity in immunosenecence and longevity within the Irish population

scientific article published on 01 August 2004

Living long and ageing well: is epigenomics the missing link between nature and nurture?

scientific article published on 02 July 2015

MTHFR thermolabile genotype frequencies and longevity in Northern Ireland

scientific article published on 01 May 1997

Malondialdehyde and measures of antioxidant activity in subjects from the Belfast Elderly Longitudinal Free-living Aging Study

scientific article published in June 2004

Mitochondrial DNA polymorphism: its role in longevity of the Irish population

scientific article published on 01 July 2001

Nature or nurture; BMI and blood pressure at 90. Findings from the Belfast Elderly Longitudinal Free-living Aging STudy (BELFAST).

scientific article

No or only population-specific effect of PON1 on human longevity: a comprehensive meta-analysis

scientific article published on April 2010

Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis

scientific article published in April 2004

Physical activity and cognitive function in individuals over 60 years of age: a systematic review

scientific article

Serum heat shock protein and anti-heat shock protein antibody levels in aging

scientific article published on 01 February 2001

Study of age-association with cytokine gene polymorphisms in an aged Irish population

article

TOTAL SERUM IL-12 AND IL-12p40, BUT NOT IL-12p70, ARE INCREASED IN THE SERUM OF OLDER SUBJECTS; RELATIONSHIP TO CD3+AND NK SUBSETS

scientific article published on 01 February 2000

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

scientific article

Towards ageing well: Use it or lose it: Exercise, epigenetics and cognition

scientific article published on 17 June 2017

mt4216C variant in linkage with the mtDNA TJ cluster may confer a susceptibility to mitochondrial dysfunction resulting in an increased risk of Parkinson's disease in the Irish

scientific article published on 01 April 2003

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