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List of works by Marc K. Halushka

2011 consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology.

scientific article published on 03 December 2011

A Comprehensive Evaluation of the Genetic Architecture of Sudden Cardiac Arrest

A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.

scientific article published on 26 September 2013

A benchmark for microRNA quantification algorithms using the OpenArray platform

scientific article

A central role of plasmin in cardiac injury initiated by fetal exposure to maternal anti-Ro autoantibodies

scientific article published on 18 April 2013

A comprehensive histopathological evaluation of vascular medial fibrosis: insights into the pathophysiology of arterial stiffening

scientific article

A critical evaluation of microRNA biomarkers in non-neoplastic disease

scientific article

A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension

scientific journal article

A draft map of the human proteome

scientific article (publication date: 29 May 2014)

A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy

scientific article published in March 2009

A novel method of measuring cardiac preservation injury demonstrates University of Wisconsin solution is associated with less ischemic necrosis than Celsior in early cardiac allograft biopsy specimens.

scientific article published on 30 December 2011

A novel role of endothelin-1 in linking Toll-like receptor 7-mediated inflammation to fibrosis in congenital heart block.

scientific article

A rasopathy phenotype with severe congenital hypertrophic obstructive cardiomyopathy associated with a PTPN11 mutation and a novel variant in SOS1.

scientific article

Ablation Lesion Characterization in Scarred Substrate Assessed Using Cardiac Magnetic Resonance

scientific article published on 26 December 2018

Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor

scientific article published on 18 September 2009

An Urgent Need for Studies of the Late Effects of SARS-CoV-2 on the Cardiovascular System

scientific article published on 24 September 2020

An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval

scientific article

An expanded proteome of cardiac t-tubules

scientific article published on 24 May 2019

Anaerobic vs aerobic pathways of carbonyl and oxidant stress in human lens and skin during aging and in diabetes: A comparative analysis

scientific article

Anatomical Structures, Cell Types, and Biomarkers Tables Plus 3D Reference Organs in Support of a Human Reference Atlas

scholarly article published 1 June 2021

Anatomical and pathological findings in hearts from fetuses and infants with cardiac manifestations of neonatal lupus

scientific article

Androgen receptor expression is usually maintained in initial surgically resected breast cancer metastases but is often lost in end-stage metastases found at autopsy.

scientific article published on 10 December 2011

Association of plasma levels of soluble receptor for advanced glycation end products and risk of kidney disease: the Atherosclerosis Risk in Communities study

scientific article

Autopsy findings of a 37-year-old man with a complex mosaic karyotype involving del(18p), monosomy 13, and trisomy 20.

scientific article published in June 2005

B cells and plasma cells in coronaries of chronically rejected cardiac transplants

scientific article published on 01 May 2010

B cells in cardiac transplants: from clinical questions to experimental models

scientific article published on 19 September 2011

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes.

scientific article published on 2 December 2011

Baseline Characteristics Predict the Presence of Amyloid on Endomyocardial Biopsy.

scientific article published on 20 December 2016

Beneficial cardiac effects of caloric restriction are lost with age in a murine model of obesity

scientific article

Benign cardiac tumors and tumorlike conditions.

scientific article published on 29 March 2010

Big Strides in Cellular MicroRNA Expression

scientific article published on 17 January 2018

Brief report: antisynthetase syndrome-associated myocarditis

scientific article published on 29 July 2014

Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPAR{alpha}/PGC1{alpha} and thermogenic glycerolipid/fatty acid cycling

scientific article

Cardiac pathology of systemic lupus erythematosus.

scientific article published on July 2009

Cardiac transplantation in arrhythmogenic right ventricular dysplasia/cardiomyopathy.

scientific article published on January 2012

Cardiomyocytes have mosaic patterns of protein expression

scientific article published on 24 March 2018

Cardiovascular pathologies in mucopolysaccharidosis type VII (Sly Syndrome).

scientific article published on 19 June 2015

Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis

scientific article

Causes and histopathology of ascending aortic disease in children and young adults.

scientific article

Cell atlas of the fetal human heart and implications for autoimmune-mediated congenital heart block

scientific article published on 07 October 2019

Cell type-specific DNA methylation patterns in the human breast

scholarly article

Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancer.

scientific article published on 8 May 2018

Characterization of human mesenchymal stem cell-engineered cartilage: analysis of its ultrastructure, cell density and chondrocyte phenotype compared to native adult and fetal cartilage

scientific article published on 18 June 2009

Citrullination of myofilament proteins in heart failure

scientific article

Clinical and Pathologic Characteristics and Predictors of Myocarditis and Recovery in Patients Undergoing Endomyocardial Biopsy for Acute Onset Heart Failure

Clinical and pathologic implications of extending the spectrum of maternal autoantibodies reactive with ribonucleoproteins associated with cutaneous and now cardiac neonatal lupus from SSA/Ro and SSB/La to U1RNP.

scientific article

Color deconvolution for the analysis of tissue microarrays

scientific article published on 01 October 2009

Complex Sources of Variation in Tissue Expression Data: Analysis of the GTEx Lung Transcriptome

scientific article

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria

scientific article

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases

scientific article

Consistent RNA sequencing contamination in GTEx and other data sets

scientific article published on 22 April 2020

Creation, validation, and quantitative analysis of protein expression in vascular tissue microarrays

scientific article

DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.

scientific article published on 10 April 2009

Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness.

scientific article published on 20 May 2010

Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini

scientific article

Endomyocardial Biopsy Characterization of Heart Failure With Preserved Ejection Fraction and Prevalence of Cardiac Amyloidosis

scientific article published on 05 July 2020

Enhanced proliferation of cultured human vascular smooth muscle cells linked to increased function of RNA-binding protein HuR

scientific article

Enrichment of Scleroderma Vascular Disease-Associated Autoantigens in Endothelial Lineage Cells

scientific article published on 9 May 2016

Enterohemorrhagic Escherichia coli reduce mucus and intermicrovillar bridges in human stem cell-derived colonoids

scientific article published on January 2016

Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases

scientific article

Evaluation of the role of endomyocardial biopsy in 851 patients with unexplained heart failure from 2000-2009.

scientific article

Exercise, vascular stiffness, and tissue transglutaminase.

scientific article

Exosomal MicroRNA-15a Transfer from the Pancreas Augments Diabetic Complications by Inducing Oxidative Stress

scientific article published on 17 March 2017

Expression of cathepsin K and tartrate-resistant acid phosphatase is not confined to osteoclasts but is a general feature of multinucleated giant cells: systematic analysis.

scientific article published on 14 May 2013

Expression of the Autoantigen Topoisomerase-1 is Enriched in the Lung Tissues of Patients With Autoimmune Interstitial Lung Disease: A Case Control Study

scientific article published on 29 October 2020

Extensive cardiac allograft vasculitis and concurrent fat necrosis 6 years after orthotopic heart transplantation

scientific article published on 27 September 2007

Extracellular vesicle microRNA transfer in cardiovascular disease.

scientific article published on 28 April 2015

Extranodal Rosai-Dorfman disease involving the heart: report of two cases

scientific article published on 12 October 2009

Fatal outcome of a calcified amorphous tumor of the heart (cardiac CAT).

scientific article published in September 2006

Fusion of aortic valve commissures in patients supported by a continuous axial flow left ventricular assist device

scientific article

GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas

scientific article published on 31 January 2013

Galectin-3 and Risk of Heart Failure and Death in Blacks and Whites

scientific article published on 13 May 2016

Gap junction remodeling in a case of arrhythmogenic right ventricular dysplasia due to plakophilin-2 mutation

scientific article published on 19 May 2008

Genetic aetiologies should be considered in paediatric cases of acute heart failure presumed to be myocarditis

scientific article published on 14 June 2019

Genetic testing improves identification of transthyretin amyloid (ATTR) subtype in cardiac amyloidosis

scientific article published on 11 May 2017

Genetic variation in cyclooxygenase 1: effects on response to aspirin

scientific article (publication date: 2003)

Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study

scientific article published on 17 June 2015

Giant Ring Mitochondria in a Patient With Heart Failure and Cerebral White Matter Disease Resulting From an MT-TL1 Mitochondrial Gene Mutation

scientific article published on 15 June 2017

Giant cell myocarditis depicted by cardiac magnetic resonance imaging

scientific article published in November 2005

Glomerular protein levels of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 are lower in diabetic subjects.

scientific article published on 08 June 2009

HPASubC: A suite of tools for user subclassification of human protein atlas tissue images

scientific article published on 23 June 2015

Haemophilus influenzae serotype f purulent pericarditis: a cause of death in a child with Down syndrome

scientific article published on 19 April 2006

Heart failure associated with sunitinib malate: a multitargeted receptor tyrosine kinase inhibitor

scientific article published in June 2008

Heart failure therapies: new strategies for old treatments and new treatments for old strategies

scientific article

Heterogeneity of Bcl-2 expression in metastatic breast carcinoma

scientific article published on 21 May 2010

Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases

scientific article

Histologic and electron microscopy findings in myocardium of treated Fabry disease

scientific article published on 01 June 2006

Histopathologic differences partially distinguish syndromic aortic diseases.

scientific article published on 15 June 2017

Histopathologic findings in ascending aortas from individuals with Loeys-Dietz syndrome (LDS).

scientific article

Human and Cow Have Identical miR-21-5p and miR-30a-5p Sequences, Which Are Likely Unsuited to Study Dietary Uptake from Cow Milk

scientific article published on 01 September 2018

Human cardiac -regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants

article published in 2018

Human cardiac myosin light chain 4 (MYL4) mosaic expression patterns vary by sex

scientific article published on 03 September 2019

HumanGFRA1: Cloning, Mapping, Genomic Structure, and Evaluation as a Candidate Gene for Hirschsprung Disease Susceptibility ⬇️

scientific article published on March 15, 1998

Identification of miR-145 targets through an integrated omics analysis.

scientific article

IgG4-related disease of the aortic valve: a report of two cases and review of the literature.

scientific article published on 28 September 2014

Increased generation of TRAP expressing multinucleated giant cells in patients with granulomatosis with polyangiitis.

scientific article

Increased lipofuscin on endomyocardial biopsy predicts greater cardiac improvement in adolescents and young adults.

scientific article published on 6 December 2011

Induction of macrophage chemotaxis by aortic extracts of the mgR Marfan mouse model and a GxxPG-containing fibrillin-1 fragment

scientific article published on 9 October 2006

Integrated Transcriptomic and Proteomic Analysis of Primary Human Umbilical Vein Endothelial Cells

scientific article published on 26 June 2019

Intracardiac giant cells after left ventricular assist device placement

scientific article published in April 2007

Intratumoral heterogeneity of HER-2 gene amplification and protein overexpression in breast cancer

scientific article

Lack of Relationship Between Serum Cardiac Troponin I Level and Giant Cell Myocarditis Diagnosis and Outcomes

scientific article published on 6 January 2016

Lessons from miR-143/145: the importance of cell-type localization of miRNAs

scientific article

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

scientific article

Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening

scientific article published on 19 April 2019

Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease

scientific article published on 09 August 2018

Melanopsin mediates light-dependent relaxation in blood vessels

scientific article

MicroRNA profiling of diverse endothelial cell types

scientific article

MicroRNA-144 is unlikely to play a role in bronchiolitis obliterans syndrome

scientific article published on 14 January 2016

Molecular definition of breast tumor heterogeneity

scientific article

Multidetector CT of the heart: spectrum of benign and malignant cardiac masses.

scientific article published on 06 June 2012

Mutations in Alström protein impair terminal differentiation of cardiomyocytes

scientific article published on 4 March 2014

Mycobacterium tuberculosis infection drives mitochondria-biased dysregulation of host tRNA-derived fragments

scientific article published on 22 September 2020

Myocardial T1 mapping: techniques and potential applications

scientific article

Myocardial calcifications: pathophysiology, etiologies, differential diagnoses, and imaging findings.

scientific article published on 22 October 2014

Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study.

scientific article

Nasopharyngeal hairy polyp with recurrence in the middle ear.

scientific article

Negative 34betaE12 staining in a small focus of atypical glands on prostate needle biopsy: a follow-up study of 332 cases

scientific article published on January 2004

New clinical and ultrastructural findings in hydroxychloroquine-induced cardiomyopathy--a report of 2 cases

scientific article published on December 2007

New concepts of complement in allorecognition and graft rejection

scientific article

No histologic evidence of foetal cardiotoxicity following exposure to maternal hydroxychloroquine

scientific article published on 06 June 2017

Novel cause of sudden cardiac death: IgG4-related disease.

scientific article

Opportunities for microRNAs in the Crowded Field of Cardiovascular Biomarkers

scientific article published on 17 October 2018

Optimization of Serum Immunoglobulin Free Light Chain Analysis for Subclassification of Cardiac Amyloidosis

scientific article published on 30 April 2015

Outcomes and predictors of recovery in acute-onset cardiomyopathy: A single-center experience of patients undergoing endomyocardial biopsy for new heart failure

scientific article published on 5 July 2016

Pathologic quiz case: a 34-year-old woman with an inguinal mass. Female adnexal tumor of probable wolffian origin

scientific article published on 01 November 2004

Pathology of the Aorta

scientific article published on 20 April 2012

Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

scientific article (publication date: July 1999)

Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity

scientific article

Polycystin signaling is required for directed endothelial cell migration and lymphatic development

scientific article

Postmortem cardiac tissue maintains gene expression profile even after late harvesting.

scientific article

Prognostic value of left ventricular apical tissue removed for HeartMate II left ventricular assist device placement.

scientific article published on 15 August 2008

Prolonged RV endocardial activation duration: a novel marker of arrhythmogenic right ventricular dysplasia/cardiomyopathy

scientific article published on 24 February 2009

RREB1 repressed miR-143/145 modulates KRAS signaling through downregulation of multiple targets

scientific article

Recommendations for processing cardiovascular surgical pathology specimens: a consensus statement from the Standards and Definitions Committee of the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology

scientific article published on 24 February 2011

Relationship between monoclonal gammopathy and cardiac amyloid type.

scientific article

Resolution of giant cell myocarditis after extended ventricular assistance

scientific article published in January 2009

Response to comments on: Maleszewski JJ et al. IgG4-related disease of the aortic valve: a report of two cases and review of the literature. Cardiovasc Pathol 2015;24(1)56-9.

scientific article published on 16 April 2015

Response to comments on: Selvin et al. sRAGE and risk of diabetes, cardiovascular disease, and death. Diabetes 2013;62:2116-2121.

scientific article published on October 2013

Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy

scientific article published on 12 May 2008

Reversible cardiomyopathy caused by administration of interferon alpha

scientific article published in January 2005

Ribonucleic artefacts: are some extracellular RNA discoveries driven by cell culture medium components?

scientific article published on 12 January 2017

Right Ventricular Myofilament Functional Differences in Humans with Systemic Sclerosis-associated versus Idiopathic Pulmonary Arterial Hypertension.

scientific article published on 19 January 2018

Right ventricle-dominant cardiac sarcoidosis with sparing of the left ventricle

scientific article published on 08 February 2006

Robust immunohistochemical staining of several classes of proteins in tissues subjected to autolysis

scientific article published on 20 February 2007

Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9.

scientific article published on 27 October 2008

Seven factors predict a delayed diagnosis of cardiac amyloidosis

scientific article published on 31 August 2018

Siglec-1 Macrophages and the Contribution of IFN to the Development of Autoimmune Congenital Heart Block

scientific article published on 05 December 2018

Sildenafil citrate protects skeletal muscle of ischemia-reperfusion injury: immunohistochemical study in rat model

scientific article published on 01 April 2013

Single cell RNA-seq analysis of the flexor digitorum brevis mouse myofibers

scientific article published on 17 May 2021

Single gene disorders of the aortic wall ⬇️

scientific article published on October 27, 2011

Soluble receptor for advanced glycation end products and the risk for incident heart failure: The Atherosclerosis Risk in Communities Study

scientific article

Spatial Proteomic Approach to Characterize Skeletal Muscle Myofibers

scientific article published on 30 November 2020

Structural and Functional Correlates of Myocardial T1 Mapping in 321 Patients With Hypertrophic Cardiomyopathy.

scientific article published on 15 December 2016

Surgical repair of aortic dissection 16 years post-Ross procedure

scientific article published on 2 May 2016

Survey of North American pathologist practices regarding antibody-mediated rejection in cardiac transplant biopsies

scientific article published on 24 April 2010

Survey of current practice related to grading of rejection in cardiac transplant recipients in North America

scientific article

T1 Mapping in cardiomyopathy at cardiac MR: comparison with endomyocardial biopsy.

scientific article

TGFβ receptor mutations impose a strong predisposition for human allergic disease

scientific article published on July 2013

Targeting downstream transcription factors and epigenetic modifications following Toll-like receptor 7/8 ligation to forestall tissue injury in anti-Ro60 associated heart block

scientific article published on 29 September 2015

The change in B-type natriuretic peptide levels over time predicts significant rejection in cardiac transplant recipients

scientific article published in July 2009

The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance

scientific article published on 20 February 2012

The effect of tissue composition on gene co-expression

scientific article published on 08 December 2019

Three-year variability in plasma concentrations of the soluble receptor for advanced glycation end products (sRAGE)

scientific article

Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking-Dependent and Crosslinking-Independent Functions.

scientific article published on 3 February 2017

Tissue inhibitor of matrix metalloproteinase-3 levels in the extracellular matrix of lung, kidney, and eye increase with age.

scientific article published on 27 October 2008

Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation

scientific article

Toward individualized analgesic therapy: functional cyclooxygenase 1 and 2 haplotypes

scientific article published on 01 May 2006

Toward the human cellular microRNAome.

scientific article published on 6 September 2017

Toward the promise of microRNAs - Enhancing reproducibility and rigor in microRNA research.

scientific article published on 19 September 2016

Tracking the clonal origin of lethal prostate cancer

scientific article published on 25 October 2013

Unexpected sclerosing mediastinitis involving the ascending aorta in the setting of a multifocal fibrosclerotic disorder

scientific article published in July 2010

Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API

scientific article published on 01 February 2020

Uptake of dietary milk miRNAs by adult humans: a validation study

scientific article

Use of a glycolipid inhibitor to ameliorate renal cancer in a mouse model

scientific article

Use of human vascular tissue microarrays for measurement of advanced glycation endproducts

scientific article published on 16 February 2009

Utilization of HPASubC for the Identification of Sinusoid-Specific Proteins in the Liver.

scientific article

Why are some individuals resistant to the cardioprotective effects of aspirin? Could it be thromboxane A2?

scientific article (publication date: 9 April 2002)

miRNA Regulation in Gliomas: Usual Suspects in Glial Tumorigenesis and Evolving Clinical Applications

scientific article

miRge - A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy

scientific article

miRge 2.0 for comprehensive analysis of microRNA sequencing data

scientific article published on 23 July 2018

miRge3.0: a comprehensive microRNA and tRF sequencing analysis pipeline

scientific article published on 21 July 2021

sRAGE and risk of diabetes, cardiovascular disease, and death

scientific article published on 8 February 2013

sRAGE, inflammation, and risk of atrial fibrillation: results from the Atherosclerosis Risk in Communities (ARIC) Study

scientific article published on 25 November 2014

xMD-miRNA-seq to generate near in vivo miRNA expression estimates in colon epithelial cells.

scientific article

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