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List of works by Kai Kisand

A dynamic COVID-19 immune signature includes associations with poor prognosis

scientific article published on 17 August 2020

A highly conserved NF-κB-responsive enhancer is critical for thymic expression of Aire in mice.

scientific article published on 14 September 2015

AIRE activated tissue specific genes have histone modifications associated with inactive chromatin

scientific article

AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies

scientific article published on 14 July 2016

AIRE-induced apoptosis is associated with nuclear translocation of stress sensor protein GAPDH.

scientific article published on 18 May 2012

Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes

scientific article published on 19 August 2015

Anti-cytokine autoantibodies preceding onset of autoimmune polyendocrine syndrome type I features in early childhood.

scientific article published on 26 October 2013

Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice

scientific article published in March 2013

Anticommensal Responses Are Associated with Regulatory T Cell Defect in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients.

scientific article

Aortic Calcification in a Patient with a Gain-of-Function STAT1 Mutation

scientific article published on 26 May 2018

Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study.

scientific article

Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis

scientific article published on 09 September 2020

Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis

scientific article published on 27 November 2020

Auto-antibodies against type I IFNs in patients with life-threatening COVID-19

scientific article published on 24 September 2020

Autoantibody Repertoire in APECED Patients Targets Two Distinct Subgroups of Proteins

scientific article published on 16 August 2017

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy

scientific article published on 05 July 2015

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy and other primary immunodeficiency diseases help to resolve the nature of protective immunity against chronic mucocutaneous candidiasis

scientific article published on December 2013

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy: known and novel aspects of the syndrome

scientific article published on December 1, 2011

Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes

scientific journal article

Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-like Autoimmune Disease

scientific article published on 29 June 2018

C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis

scientific article published on 18 September 2017

Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

scientific article

Clinical and serologic parallels to APS-I in patients with thymomas and autoantigen transcripts in their tumors

scientific article

Clinical, Genetic and Immunological Characteristics of Paediatric Autoimmune Polyglandular Syndrome Type 1 Patients in Slovenia

scientific article published on 13 March 2015

CpG sites associated with NRP1, NRXN2 and miR-29b-2 are hypomethylated in monocytes during ageing

scientific article published on 09 January 2014

DNA breaks and chromatin structural changes enhance the transcription of autoimmune regulator target genes

scientific article published on 27 February 2017

DNA methylation signatures of the AIRE promoter in thymic epithelial cells, thymomas and normal tissues.

scientific article published on 27 October 2011

DNA-PK contributes to the phosphorylation of AIRE: importance in transcriptional activity

scientific article published on 4 October 2007

Double Trouble? CMC with a Mutation in both AIRE and STAT1

scientific article published on 27 July 2018

Dysregulation of adaptive immune responses in complement C3-deficient patients

scientific article published on 19 January 2015

Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling

scientific article published on 09 October 2015

Flow cytometry study of blood cell subtypes reflects autoimmune and inflammatory processes in autoimmune polyendocrine syndrome type I.

scientific article

Genome-wide promoter analysis of histone modifications in human monocyte-derived antigen presenting cells

scientific article

Higher FoxP3 mRNA expression in peripheral blood mononuclear cells of GAD65 or IA-2 autoantibody-positive compared with autoantibody-negative persons.

scientific article published in October 2008

Human genetic and immunological determinants of critical COVID-19 pneumonia

scientific article published on 28 January 2022

Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells

scientific article

IL-22 neutralizing autoantibodies impair fungal clearance in murine oropharyngeal candidiasis model

scientific article published on 17 November 2017

IL-6-specific autoantibodies among APECED and thymoma patients

scientific article published on 25 May 2016

IgG from patients with liver diseases inhibit mitochondrial respiration in permeabilized oxidative muscle cells: impaired function of intracellular energetic units?

scientific article

Impaired salivary gland activity in patients with autoimmune polyendocrine syndrome type I.

scientific article

In vivo analysis of helper T cell responses in patients with autoimmune polyendocrinopathy - candidiasis - ectodermal dystrophy provides evidence in support of an IL-22 defect

scientific article

Incontinentia pigmenti in a female conceived by in vitro fertilization.

scientific article

Increased microRNA-323-3p in IL-22/IL-17-producing T cells and asthma: a role in the regulation of the TGF-β pathway and IL-22 production

scientific article published on 5 April 2016

Interferon and interferon-inducible gene activation in patients with type 1 diabetes

scientific article published on October 2014

Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes

scientific article published on 07 July 2008

Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined

scientific article published on 07 March 2019

Irf4 Expression in Thymic Epithelium Is Critical for Thymic Regulatory T Cell Homeostasis

scientific article published on 20 January 2017

LIPS method for the detection of SARS-CoV-2 antibodies to spike and nucleocapsid proteins

scientific article published on 25 June 2020

Longitudinal proteomic profiling reveals increased early inflammation and sustained apoptosis proteins in severe COVID-19

scientific article published on 25 November 2020

Lymphopenia-induced proliferation in aire-deficient mice helps to explain their autoimmunity and differences from human patients

scientific article

Metallophilic macrophages are fully developed in the thymus of autoimmune regulator (Aire)-deficient mice

scientific article published on 16 January 2009

MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal miR-511 as putative positive regulator of Toll-like receptor 4.

scientific article published on 6 June 2011

MicroRNA-155 is Dysregulated in the Skin of Patients with Vitiligo and Inhibits Melanogenesis-associated Genes in Melanocytes and Keratinocytes

scientific article published in August 2016

Modulation of Aire regulates the expression of tissue-restricted antigens

scientific journal article

Mucocutaneous candidiasis and autoimmunity against cytokines in APECED and thymoma patients: clinical and pathogenetic implications

scientific article published on 13 May 2011

Oxidative stress in leucocytospermic prostatitis patients: preliminary results

scientific article published in June 2008

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

scientific article

Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens

scientific article published in March 2012

Pregnancy-induced thymic involution is associated with suppression of chemokines essential for T-lymphoid progenitor homing

scientific article published on 09 June 2016

Primary biliary cirrhosis: a multi-faced interactive disease involving genetics, environment and the immune response

scientific article published on 15 May 2012

Propensity to excessive proinflammatory response in chronic Lyme borreliosis

article

Response to comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

scientific article published on 27 June 2019

SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis

scientific article published on 11 August 2015

Signs of innate immune activation and premature immunosenescence in psoriasis patients

scientific article published on 8 August 2017

TNF superfamily members play distinct roles in shaping the thymic stromal microenvironment

scientific article published on 21 March 2016

Ultrastructure of medullary thymic epithelial cells of autoimmune regulator (Aire)-deficient mice

scientific article published on 01 September 2009

Unexplained cyanosis caused by hepatopulmonary syndrome in a girl with APECED syndrome

scientific article published on 21 February 2017

Unstimulated Adult Human B Cells Include an IL-10+ Population with Suppressive Properties and an Activated Phenotype

article

miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis

scientific article published on 05 June 2017