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List of works by Noel Clarke

A contemporary standard for morbidity and outcome after radical cystectomy

scientific article published on 17 April 2009

A correlation of FTIR spectra derived from prostate cancer biopsies with gleason grade and tumour stage

scientific article

A potential role of heat shock proteins and nicotinamide N-methyl transferase in predicting response to radiation in bladder cancer.

scientific article

Abarelix and other gonadotrophin-releasing hormone antagonists in prostate cancer.

scientific article published on December 2009

Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.

scientific article published on 3 June 2017

Abiraterone in "High-" and "Low-risk" Metastatic Hormone-sensitive Prostate Cancer

scientific article published on 23 August 2019

Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial

scientific article published on 21 December 2015

Adjuvant and salvage treatment after radical prostatectomy: current practice in the UK

scientific article published on 01 January 2005

Aetiology, diagnosis and management of urothelial tumours of the renal pelvis and ureter

scientific article published on 01 November 2008

An evaluation of gemcitabines differential radiosensitising effect in related bladder cancer cell lines

scientific article published on January 2004

Applications of Fourier transform infrared microspectroscopy in studies of benign prostate and prostate cancer. A pilot study

scientific article published in September 2003

Arachidonic acid induction of Rho-mediated transendothelial migration in prostate cancer

scientific article published on 04 March 2014

Assessing the challenges of Fourier transform infrared spectroscopic analysis of blood serum.

scientific article published on 31 January 2014

Balancing toxicity and efficacy: learning from trials and treatment using antiresorptive therapy in prostate cancer

scientific article

Biomolecular profiling of metastatic prostate cancer cells in bone marrow tissue using FTIR microspectroscopy: a pilot study

scientific article published in February 2007

Bisphosphonates in hormone-refractory prostate cancer: do we have a toxicity problem?

scientific article published on 03 August 2008

CD133: A MARKER OF TRANSIT AMPLIFICATION RATHER THAN STEM CELL PHENOTYPE IN THE PROSTATE?

scientific article published in April 2009

Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09).

scientific article published on 4 March 2013

Cardiovascular risk with androgen deprivation therapy for prostate cancer: potential mechanisms

scientific article published on 30 June 2015

Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial

scientific article

Characterising cytotoxic agent action as a function of the cell cycle using Fourier transform infrared microspectroscopy

scientific article published on June 2015

Characterization of benign and malignant prostate epithelial Hoechst 33342 side populations

scientific article

Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cells

scientific article

Chemotherapy in hormone refractory prostate cancer: where do we stand?

scientific article published on 01 December 2004

Classification of fixed urological cells using Raman tweezers

scientific article

Clinical guidelines: should 5 alpha-reductase inhibitors be used for prostate disease?

scientific article published on 01 July 2009

Combining Enzalutamide with Abiraterone, Prednisone, and Androgen Deprivation Therapy in the STAMPEDE Trial

scientific article published on 27 June 2014

Coming Up for Air: Follow-up and Risk Stratification After Negative Prostate Cancer Screening

scientific article published on August 13, 2012

Comparison of complications after transrectal and transperineal prostate biopsy: a national population-based study

scientific article published on 02 March 2020

Comparison of the cellular molecular stress responses after treatments used in bladder cancer

scientific article published in December 2002

Complications arising in the final year of life in men dying from advanced prostate cancer

scientific article published in June 2007

Copper modulates zinc metalloproteinase-dependent ectodomain shedding of key signaling and adhesion proteins and promotes the invasion of prostate cancer epithelial cells

scientific article published on 30 August 2012

CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma.

scientific article published on 03 June 2009

Development of a novel rapid assay to assess the fidelity of DNA double-strand-break repair in human tumour cells.

scientific article published on January 2002

Differential complication rates following radical cystectomy in the irradiated and nonirradiated pelvis

scientific article published on 10 December 2009

Differential inhibition of invasion and proliferation by bisphosphonates: anti-metastatic potential of Zoledronic acid in prostate cancer

scientific article published on September 2004

Differential radiosensitisation by ZD1839 (Iressa), a highly selective epidermal growth factor receptor tyrosine kinase inhibitor in two related bladder cancer cell lines

scientific article published on January 2005

Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopy

article

Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

scientific article published on 30 November 2007

Discrimination of prostate cancer cells by reflection mode FTIR photoacoustic spectroscopy

scientific article published on 8 March 2007

Disodium pamidronate identifies differential osteoclastic bone resorption in metastatic prostate cancer

scientific article published in January 1992

Disturbance in sodium regulating hormones in chronic obstructive uropathy

scientific article published on August 1991

Dynamic sentinel lymph node biopsy for penile cancer: a comparison between 1- and 2-day protocols

scientific article published on 8 December 2015

E-cadherin and beta-catenin are down-regulated in prostatic bone metastases

scientific article

Early hormonal data from a multicentre phase II trial using transdermal oestrogen patches as first-line hormonal therapy in patients with locally advanced or metastatic prostate cancer.

scientific article

Early prostate cancer--which treatment do men prefer and why?

scientific article published on 17 November 2010

Editorial comment on: noninvasive detection of testicular carcinoma in situ in semen using OCT3/4

scientific article published on 01 November 2007

Enhanced FTIR bench-top imaging of single biological cells

scientific article

Event-Free Survival, a Prostate-Specific Antigen-Based Composite End Point, Is Not a Surrogate for Overall Survival in Men With Localized Prostate Cancer Treated With Radiation

scientific article published on 18 June 2020

Exploring the spectroscopic differences of Caki-2 cells progressing through the cell cycle while proliferating in vitro

scientific article published on 3 May 2013

External urethral sphincter electromyography in asymptomatic women and the influence of the menstrual cycle

scientific article published on 20 January 2015

FTIR microscopy of biological cells and tissue: data analysis using resonant Mie scattering (RMieS) EMSC algorithm

scientific article published on 9 February 2012

FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder

scientific article published on 2 November 2012

FTIR-based spectroscopic analysis in the identification of clinically aggressive prostate cancer.

scientific article

Factors influencing the discrimination and classification of prostate cancer cell lines by FTIR microspectroscopy

scientific article

Failure-Free Survival and Radiotherapy in Patients With Newly Diagnosed Nonmetastatic Prostate Cancer: Data From Patients in the Control Arm of the STAMPEDE Trial

scientific article

Fixation protocols for subcellular imaging by synchrotron-based Fourier transform infrared microspectroscopy

scientific article

Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial

scientific article

Flexible trial design in practice – dropping and adding arms in STAMPEDE: a multi-arm multi-stage randomised controlled trial

scientific article

Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival

scientific article published on 09 May 2007

Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma

scientific article published on 15 January 2008

Genome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma.

scientific article published in March 2012

Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma

article

Highlighting a need to distinguish cell cycle signatures from cellular responses to chemotherapeutics in SR-FTIR spectroscopy

scientific article

Histological outcome of delayed orchidectomy after primary chemotherapy for metastatic germ cell tumour of the testis

scientific article

Hoechst 33342 side population identification is a conserved and unified mechanism in urological cancers

scientific article

Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma

scientific article

Identifying skeletal-related events for prostate cancer patients in routinely collected hospital data

scientific article published on 09 November 2019

Imaging angiogenesis of genitourinary tumors.

scientific article published on 19 January 2010

Implementing newer agents for the management of castrate-resistant prostate cancer: what is known and what is needed?

scientific article published on 15 July 2014

Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer

scientific article

Integrating surgery with targeted therapies for renal cell carcinoma: maximizing benefits, minimizing risk

scientific article published on 26 September 2010

Interaction of prostate epithelial cells from benign and malignant tumor tissue with bone-marrow stroma

scientific article published on 01 February 1998

Interactions of human prostatic epithelial cells with bone marrow endothelium: binding and invasion

scientific article

Invasive phenotype of primary human prostatic epithelial cells.

scientific article

Investigating FTIR based histopathology for the diagnosis of prostate cancer

scientific article published in February 2009

Investigating cellular responses to novel chemotherapeutics in renal cell carcinoma using SR-FTIR spectroscopy

scientific article published on October 2012

Is Population Screening for Prostate Cancer Good or Bad?

scientific article published on 01 December 2010

Is it safe to insert a testicular prosthesis at the time of radical orchidectomy for testis cancer: an audit of 904 men undergoing radical orchidectomy.

scientific article

Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial

scientific article published on 11 June 2009

Ki-67 index in metastatic prostate cancer

scientific article

Labelling of tumour cells with a biotinylated inhibitor of a cell surface protease

scientific article published on 01 January 1991

Landmarks in non‐hormonal pharmacological therapies for castration‐resistant prostate cancer

scientific article published on October 1, 2012

Late tissue effects following radiotherapy and neoadjuvant hormone therapy of the prostate measured with quantitative magnetic resonance imaging

scientific article

Ligand-independent activation of EphA2 by arachidonic acid induces metastasis-like behaviour in prostate cancer cells.

scientific article

Light penetration in bladder tissue: implications for the intravesical photodynamic therapy of bladder tumours

scientific article published in October 2000

Maintaining success, reducing treatment burden, focusing on survivorship: highlights from the third European consensus conference on diagnosis and treatment of germ-cell cancer.

scientific article published on 14 November 2012

Male adnexal tumour of probable Wolffian duct origin

scientific article

Male adnexal tumour of wolffian origin: the first report of metastatic disease

scientific article published on 01 January 2009

Malignant nerve sheath tumour with epithelial elements

scientific article published on 01 May 1988

Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019

scientific article published on 27 January 2020

Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017.

scientific article

Management of the spectrum of hormone refractory prostate cancer.

scientific article published on 2 June 2006

Measurement of elastic properties of prostate cancer cells using AFM.

scientific article published on 25 July 2008

Metastasis-Free Survival Is a Strong Surrogate of Overall Survival in Localized Prostate Cancer

scientific article published on 10 August 2017

Methylation profiling and evaluation of demethylating therapy in renal cell carcinoma.

scientific article published on 13 September 2013

Morphometric evidence for bone resorption and replacement in prostate cancer

scientific article published on 01 July 1991

Nasty or Nice? Findings from a UK Survey to evaluate the impact of the National Institute for Health and Clinical Excellence (NICE) clinical guidelines on the management of prostate cancer.

scientific article published on 15 October 2012

Natural history and treatment of bone complications in prostate cancer

scientific article

Non-surgical interventions for late radiation cystitis in patients who have received radical radiotherapy to the pelvis.

scientific article

Open to debate. The Motion: all men over the age of 50 should be encouraged to take a 5alpha-reductase inhibitor to prevent prostate cancer

scientific article

Open to debate. The motion: GnRH antagonists are the new way forward in hormonal therapy

scientific article published on 2 December 2009

Optical artefacts in transflection mode FTIR microspectroscopic images of single cells on a biological support: the effect of back-scattering into collection optics

scientific article

Optimisation of an immunohistochemistry method for the determination of androgen receptor expression levels in circulating tumour cells

scientific article

Osteoblast function and osteomalacia in metastatic prostate cancer

scientific article published on 01 January 1993

Osteoclast inhibition by pamidronate in metastatic prostate cancer: a preliminary study

scientific article published on March 1991

Paradoxical expression of E-cadherin in prostatic bone metastases

scientific article published on 01 December 1999

Parathyroid hormone-related peptide: expression in prostate cancer bone metastases

scientific article published in January 2002

Phase I study of conformal radiotherapy with concurrent gemcitabine in locally advanced bladder cancer

scientific article published in February 2005

Phase II Study of Conformal Hypofractionated Radiotherapy With Concurrent Gemcitabine in Muscle-Invasive Bladder Cancer

scientific article published on 04 January 2011

Photodynamic therapy

scientific article published on 01 November 1999

Preferential preservation of bone mineralisation by LHRH agonists in the treatment of metastatic prostate cancer

scientific article published in January 1991

Primary lymphoma of the urinary bladder

scientific article published on 01 August 1991

Primary peripheral primitive neuroectodermal tumour of urinary bladder

scientific article published on 01 May 1997

Primary prostatic epithelial cell binding to human bone marrow stroma and the role of alpha2beta1 integrin

scientific article published on 01 May 1997

Prognostic relevance of micro-vessel density in cancer of the urinary bladder

scientific article published on 01 July 1999

Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs

scientific article published on March 2006

Prostate radiotherapy for men with metastatic disease: a new comparison in the STAMPEDE trial

scientific article published on 13 March 2013

Prostate radiotherapy for men with metastatic disease: a new comparison in the Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy (STAMPEDE) trial

scientific article

Quantification of skeletal metastases in castrate-resistant prostate cancer predicts progression-free and overall survival

scientific article published on 27 July 2014

RADICALS (Radiotherapy and Androgen Deprivation in Combination after Local Surgery)

scientific article published on 07 February 2007

RMieS-EMSC correction for infrared spectra of biological cells: extension using full Mie theory and GPU computing

scientific article published in August 2010

Radiotherapy and androgen deprivation in combination after local surgery (RADICALS): A new Medical Research Council/National Cancer Institute of Canada phase III trial of adjuvant treatment after radical prostatectomy

article

Re: Umberto Capitanio, Shahrokh F. Shariat, Hendrik Isbarn, et al. Comparison of oncologic outcomes for open and laparoscopic nephroureterectomy: a multi-institutional analysis of 1249 cases. Eur Urol 2009;56:1-9

scientific article published on 16 December 2009

Reflection contributions to the dispersion artefact in FTIR spectra of single biological cells

scientific article

Reflections on attempted Anglo-Japanese collaboration on STAMPEDE: A randomized controlled trial for men with prostate cancer

article

Release of macrophage migration inhibitory factor by neuroendocrine-differentiated LNCaP cells sustains the proliferation and survival of prostate cancer cells.

scientific article

Repurposing Metformin as Therapy for Prostate Cancer within the STAMPEDE Trial Platform

scientific article published on 19 July 2016

Resonant Mie scattering (RMieS) correction of infrared spectra from highly scattering biological samples

scientific article published on 15 December 2009

Role of proteolytic enzymes in human prostate bone metastasis formation: in vivo and in vitro studies.

scientific article published on April 2002

SMALLPOX VACCINATION: ABO AND RHESUS BLOOD GROUPS.

scientific article published on June 1965

SR-FTIR spectroscopy of renal epithelial carcinoma side population cells displaying stem cell-like characteristics.

scientific article published on 27 October 2010

STAMPEDE: Systemic Therapy for Advancing or Metastatic Prostate Cancer--a multi-arm multi-stage randomised controlled trial

scientific article published on 29 August 2008

Scatter factor influences the formation of prostate epithelial cell colonies on bone marrow stroma in vitro

scientific article published on 01 June 1999

Should All Patients Receive Statins to Reduce Cancer Risk After Heart Transplantation?

scientific article published on 24 July 2012

Smallpox Vaccination

Smallpox vaccination. Success rates of scratch and multiple pressure techniques

scientific article published on 01 August 1963

Spectral discrimination of live prostate and bladder cancer cell lines using Raman optical tweezers

scientific article

Survival from prostate cancer in England and Wales up to 2001.

scientific article

Survival with Newly Diagnosed Metastatic Prostate Cancer in the "Docetaxel Era": Data from 917 Patients in the Control Arm of the STAMPEDE Trial (MRC PR08, CRUK/06/019).

scientific article

Systemic therapy for advancing or metastatic prostate cancer (STAMPEDE): a multi-arm, multistage randomized controlled trial

scientific article

Targeted caval cytoreduction: solid foundations or shifting sands?

scientific article

The Influence of Lipid Metabolism on Prostate Cancer Development and Progression: Is it Time for a Closer Look?

scientific article published in July 2007

The Melbourne Consensus Statement on the early detection of prostate cancer

scientific article published on February 2014

The combined application of FTIR microspectroscopy and ToF-SIMS imaging in the study of prostate cancer

scientific article published on January 2004

The differential effects of statins on the metastatic behaviour of prostate cancer.

scientific article published on 24 April 2012

The effects of orchidectomy on skeletal metabolism in metastatic prostate cancer

scientific article published on 01 January 1993

The increased rate of prostate specific antigen testing has not affected prostate cancer presentation in an inner city population in the UK.

scientific article

The management of hormone-relapsed prostate cancer.

scientific article published on November 2003

The molecular staging of prostate cancer.

scientific article

The natural history of postoperative renal function in patients undergoing ileal conduit diversion for cancer measured using serial isotopic glomerular filtration rate and 99m technetium-mercaptoacetyltriglycine renography

scientific article published on 01 December 2006

The origin of the bone scan as a tumour marker in prostate cancer

scientific article published on 07 September 2006

The post-cystectomy pseudotumour sign: MRI appearances of a modified chronic pelvic haematoma due to retained haemostatic gauze

scientific article published on 01 December 2000

The staged management of complex entero-urinary fistulae

scientific article published in October 2000

This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols.

scientific article

UBE2QL1 is disrupted by a constitutional translocation associated with renal tumor predisposition and is a novel candidate renal tumor suppressor gene

scientific article

Underground drainage

scientific article published in January 1959

Urinary incontinence following urethral Wallstent insertion

scientific article published on 01 May 1994

Urinary tract obstruction and nephrostomy drainage in pelvic malignant disease

scientific article published on 01 November 1995

Whole organ cross-section chemical imaging using label-free mega-mosaic FTIR microscopy

scientific article published on 9 October 2013

[Testis cancer: the UK as a model]

scientific article published on 01 April 2009