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List of works by Andy C Rawstron

A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study.

scientific article published on 7 December 2015

A global expression-based analysis of the consequences of the t(4;14) translocation in myeloma

scientific article published in September 2004

A molecular study of the t(4;14) in multiple myeloma

scientific article published in August 2002

A phase 1 study to address the safety and efficacy of granulocyte colony-stimulating factor for the mobilization of hematopoietic progenitor cells in active rheumatoid arthritis

scientific article published on 01 October 1997

A randomized phase II trial of fludarabine, cyclophosphamide and mitoxantrone (FCM) with or without rituximab in previously treated chronic lymphocytic leukaemia

scientific article published on 14 January 2011

A single-tube six-colour flow cytometry screening assay for the detection of minimal residual disease in myeloma

scientific article published on 26 July 2007

Abatacept or tocilizumab after rituximab in rheumatoid arthritis? An exploratory study suggests non-response to rituximab is associated with persistently high IL-6 and better clinical response to IL-6 blocking therapy

scientific article published on 2 January 2014

Alemtuzumab in combination with methylprednisolone is a highly effective induction regimen for patients with chronic lymphocytic leukemia and deletion of TP53: final results of the national cancer research institute CLL206 trial

scientific article published on 09 April 2012

An extra dose of rituximab improves clinical response in rheumatoid arthritis patients with initial incomplete B cell depletion: a randomised controlled trial

scientific article published on 17 January 2014

Analysis of CD34+ cell subsets in stem cell harvests can more reliably predict rapidity and durability of engraftment than total CD34+ cell dose, but steady state levels do not correlate with bone marrow reserve

scientific article published in September 2001

Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma

scientific article published in July 2010

Assessing minimal residual disease in chronic lymphocytic leukemia

scientific article published on January 2008

Assessment of IgH PCR strategies in multiple myeloma.

scientific article published on August 1996

Assessment of bone marrow response in Waldenström's macroglobulinemia

scientific article

Assessment of minimal residual disease in myeloma and the need for a consensus approach

scientific article published on 22 July 2015

Association of Minimal Residual Disease With Superior Survival Outcomes in Patients With Multiple Myeloma: A Meta-analysis ⬇️

scientific article

Autologous stem cell transplantation in chronic myeloid leukaemia using Philadelphia chromosome negative blood progenitors mobilised with hydroxyurea and G-CSF.

scientific article published in March 1998

B cell biomarkers of rituximab responses in systemic lupus erythematosus

scientific article published in October 2011

B-cell chronic lymphocytic leukaemia cells show specific changes in membrane protein expression during different stages of cell cycle

scientific article published in November 2007

B-lymphocyte suppression in multiple myeloma is a reversible phenomenon specific to normal B-cell progenitors and plasma cell precursors

scientific article published on 01 January 1998

Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration

scientific article

CD4+CD25+FoxP3+regulatory T cells are increased whilst CD3+CD4−CD8−αβTCR+Double Negative T cells are decreased in the peripheral blood of patients with multiple myeloma which correlates with disease burden

CD52 expression in Waldenstrom's macroglobulinemia: implications for alemtuzumab therapy and response assessment

scientific article published in March 2005

CD52 expression patterns in myeloma and the applicability of alemtuzumab therapy

scientific article published on 17 October 2006

Campath-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia

scientific article published in March 2002

Chemotherapy plus Ofatumumab at Standard or Mega dose in relapsed CLL (COSMIC) trial: study protocol for a phase II randomised controlled trial ⬇️

scientific article published on 20 September 2016

Chronic lymphocytic leukaemia (CLL) and CLL-type monoclonal B-cell lymphocytosis (MBL) show differential expression of molecules involved in lymphoid tissue homing

scientific article published in January 2010

Circulating plasma cells in multiple myeloma: characterization and correlation with disease stage.

scientific article published in April 1997

Circulating primitive stem cells in paroxysmal nocturnal hemoglobinuria (PNH) are predominantly normal in phenotype but granulocyte colony-stimulating factor treatment mobilizes mainly PNH stem cells.

scientific article published in June 1998

Clinical and diagnostic implications of monoclonal B-cell lymphocytosis

scientific article published on March 2010

Clinical cytometry in Europe, 2012

scientific article published in October 2012

Clonal lymphocytes in persons without known chronic lymphocytic leukemia (CLL): implications of recent findings in family members of CLL patients

scientific article published in July 2004

Commentary: Comparison of current flow cytometry methods for monoclonal B cell lymphocytosis detection

scientific article

Consensus guidelines for myeloma minimal residual disease sample staining and data acquisition

scientific article

Consensus guidelines on plasma cell myeloma minimal residual disease analysis and reporting

scientific article published on 23 January 2015

Controversies surrounding the clonogenic origin of multiple myeloma

scientific article published on 01 July 2000

Cyclooxygenase-2 (COX-2) in multiple myeloma: prognostic factor or therapeutic target?

scientific article published on 01 January 2007

DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma

scientific article published on 18 April 2013

Defining IgM multiple myeloma

scholarly article by Roger G Owen et al published 14 July 2011 in American Journal of Hematology

Demonstration of a germinal center immunophenotype in lymphomas by immunocytochemistry and flow cytometry

scientific article published in January 2005

Detection of clonal immunoglobulin gene rearrangements in the peripheral blood progenitor cells of patients with multiple myeloma: the potential role of purging with CD34 positive selection.

scientific article

Diagnostic criteria for monoclonal B-cell lymphocytosis

scientific article

Different biology and clinical outcome according to the absolute numbers of clonal B-cells in monoclonal B-cell lymphocytosis (MBL).

scientific article published on January 2010

Distribution of myeloma plasma cells in peripheral blood and bone marrow correlates with CD56 expression

scientific article published on 01 January 1999

Early prediction of outcome and response to alemtuzumab therapy in chronic lymphocytic leukemia

scientific article published on 20 November 2003

Eradicating minimal residual disease in chronic lymphocytic leukemia: should this be the goal of treatment?

scientific article published on January 2010

Eradication of minimal residual disease improves overall and progression-free survival in patients with chronic lymphocytic leukaemia, evidence from NCRN CLL207: a phase II trial assessing alemtuzumab consolidation ⬇️

scientific article published on 29 December 2016

Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival

scientific article published on 28 February 2005

EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes

scientific article

Evaluation of ZAP-70 expression by flow cytometry in chronic lymphocytic leukemia: A multicentric international harmonization process

scientific article published on 01 July 2006

Extramedullary plasmacytoma are characterized by a ‘myeloma-like’ immunophenotype and genotype and occult bone marrow involvement

scientific article published on 29 September 2010

Extramedullary plasmacytoma with a t(11;14)(q13;q32) and aggressive clinical course

scientific article published on 01 July 2010

FICTION-TSA analysis of the B-cell compartment in myeloma shows no significant expansion of myeloma precursor cells.

scientific article published in July 1999

FcRL5 as a target of antibody-drug conjugates for the treatment of multiple myeloma

scientific article

Flow cytometric disease monitoring in multiple myeloma: the relationship between normal and neoplastic plasma cells predicts outcome after transplantation

scientific article published in November 2002

Flow cytometric protein expression profiling as a systematic approach for developing disease-specific assays: identification of a chronic lymphocytic leukaemia-specific assay for use in rituximab-containing regimens

scientific article published on 19 October 2006

Flow cytometry detection of minimal residual disease in multiple myeloma: Lessons learned at FDA-NCI roundtable symposium

scholarly article by Ola Landgren et al published 19 November 2014 in American Journal of Hematology

Genomic characterization of the chromosomal breakpoints of t(4;14) of multiple myeloma suggests more than one possible aetiological mechanism

scientific article published in February 2003

Heterogeneity of Histological Transformation Events in Waldenström's Macroglobulinemia (WM) and Related Disorders

scientific article published on 01 February 2011

High-producer haplotypes of tumor necrosis factor alpha and lymphotoxin alpha are associated with an increased risk of myeloma and have an improved progression-free survival after treatment.

scientific article published in August 2000

Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis

scientific article published in October 2008

Human peripheral blood B-cell compartments: a crossroad in B-cell traffic.

scientific article published on January 2010

Ibrutinib induces chromatin reorganisation of chronic lymphocytic leukaemia cells

scientific article published on 10 May 2019

IgM myeloma with t(4;14)(p16;q32)

article

IgM myeloma: a rare entity characterized by a CD20-CD56-CD117- immunophenotype and the t(11;14).

scientific article published in March 2008

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL.

scientific article published on 17 April 2013

Immunoglobulin M concentration in Waldenström macroglobulinemia: correlation with bone marrow B cells and plasma cells

scientific article

Immunoglobulin heavy chain sequence analysis in Waldenstrom's macroglobulinemia and immunoglobulin M monoclonal gammopathy of undetermined significance

scientific article published in July 2006

Immunophenotypic and DNA genotypic analysis of T-cell and NK-cell subpopulations in patients with B-cell chronic lymphocytic leukaemia (B-CLL).

scientific article published in January 1995

Immunophenotyping of plasma cells

scientific article

Improving efficiency and sensitivity: European Research Initiative in CLL (ERIC) update on the international harmonised approach for flow cytometric residual disease monitoring in CLL.

scientific article published on 31 July 2012

In multiple myeloma, only a single stage of neoplastic plasma cell differentiation can be identified by VLA-5 and CD45 expression.

scientific article published in June 2001

In vitro generation of long-lived human plasma cells.

scientific article published on 16 November 2012

Inherited genetic susceptibility to monoclonal B-cell lymphocytosis

scientific article

Inherited genetic susceptibility to monoclonal gammopathy of unknown significance

scientific article published on 21 January 2014

Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion

scientific article published in October 2002

Insertional events as well as translocations may arise during aberrant immunoglobulin switch recombination in a patient with multiple myeloma

scientific article published in February 2001

Interleukin 6, tumour necrosis factor alpha and lymphotoxin alpha polymorphisms in monoclonal gammopathy of uncertain significance and multiple myeloma

scientific article published on 01 January 2001

International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia

scientific article published on 15 March 2007

Is MRD eradication a desirable goal in CLL?

scientific article published on March 2010

Isotype class switching and the pathogenesis of multiple myeloma.

scientific article

Liposomal daunorubicin:in vitro andin vivo efficacy in multiple myeloma

scientific article published in June 1998

Management of nonresponse to rituximab in rheumatoid arthritis: predictors and outcome of re-treatment

scientific article

Measuring disease levels in myeloma using flow cytometry in combination with other laboratory techniques: Lessons from the past 20 years at the Leeds Haematological Malignancy Diagnostic Service

scientific article published on 03 July 2015

Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: impact on outcome in the Medical Research Council Myeloma IX Study

scientific article published on 3 June 2013

Minimal residual disease assessment in chronic lymphocytic leukaemia

scientific article published on September 2007

Minimal residual disease detection in myeloma: no more molecular remissions?

scientific article published in October 2005

Minimal residual disease following autologous stem cell transplant in myeloma: impact on outcome is independent of induction regimen

scientific article published on 15 October 2015

Minimal residual disease in myeloma by flow cytometry: independent prediction of survival benefit per log reduction

scientific article

Minimal residual disease is an independent predictor for 10-year survival in CLL. ⬇️

scientific article published on 3 October 2016

Minimal residual disease monitoring in multiple myeloma.

scientific article

Minimal residual disease monitoring in multiple myeloma: flow cytometry is the method of choice

scientific article published on 01 March 2005

Mobilization of Philadelphia-negative peripheral blood mononuclear cells in chronic myeloid leukaemia using hydroxyurea and G-CSF (filgrastim).

scientific article published on June 1996

Molecular characteristics and gene segment usage in IGH gene rearrangements in multiple myeloma.

scientific article published in July 2005

Monoclonal B Cell Lymphocytosis—What Does It Really Mean? ⬇️

scientific article published on March 1, 2013

Monoclonal B lymphocytes with the characteristics of "indolent" chronic lymphocytic leukemia are present in 3.5% of adults with normal blood counts

scientific article

Monoclonal B-cell lymphocytosis

scientific article published on 01 January 2009

Monoclonal B-cell lymphocytosis (MBL) in CLL families: substantial increase in relative risk for young adults

scientific article published on 01 April 2006

Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia

scientific article

Monoclonal B-cell lymphocytosis: good news for patients and CLL investigators

scientific article published in June 2007

Occult B-cell lymphoproliferative disorders

scientific article published on January 2011

Outcome prediction in plasmacytoma of bone: a risk model utilizing bone marrow flow cytometry and light-chain analysis

scientific article published on 17 June 2014

Outreach monitoring service for patients with indolent B-cell and plasma cell disorders: a UK experience

scientific article published on 25 October 2007

Overview of monoclonal B-cell lymphocytosis

scientific article

Peripheral blood stem cell transplantation in myeloma using CD34 selected cells.

scientific article published in May 1996

Positive and negative selection to reduce tumour contamination in peripheral blood stem cell harvests

scientific article published in September 2000

Prevalence and characteristics of monoclonal B-cell lymphocytosis (MBL) in healthy individuals and the relationship with clinical disease.

scientific article published in April 2004

Prevalence of monoclonal B-cell lymphocytosis: a systematic review

scientific article

Quantitation of minimal disease levels in chronic lymphocytic leukemia using a sensitive flow cytometric assay improves the prediction of outcome and can be used to optimize therapy

scientific article published on July 2001

Re-treatment of rheumatoid arthritis patients who were initial nonresponders to rituximab: comment on the article by Thurlings et al.

scientific article published in June 2009

Reduced-dose rituximab in rheumatoid arthritis: efficacy depends on degree of B cell depletion.

scientific article published in March 2011

Repeat cycles of rituximab on clinical relapse in ANCA-associated vasculitis: identifying B cell biomarkers for relapse to guide retreatment decisions ⬇️

scientific article published on 8 April 2015

Reply to M. Roschewski et al.

scientific article published on 13 January 2014

Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders

scientific article published on 11 February 2008

Reproducible diagnosis of chronic lymphocytic leukemia by flow cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation project

scientific article

Response assessment in Waldenström macroglobulinaemia: update from the VIth International Workshop

scientific article

Response to Dr Bredemeier's letter

scientific article published on 14 March 2014

Results of the randomized phase IIB ARCTIC trial of low-dose rituximab in previously untreated CLL. ⬇️

scientific article published on 24 March 2017

Risk-stratified adoptive cellular therapy following allogeneic hematopoietic stem cell transplantation for advanced chronic lymphocytic leukaemia

article

Rituximab plus chlorambucil as first-line treatment for chronic lymphocytic leukemia: Final analysis of an open-label phase II study

scientific article

Serum siliac acid in patients with multiple myeloma

scientific article published on 01 March 1997

Successful treatment of resistant scleroderma-associated interstitial lung disease with rituximab

article

TRUE SPECTRUM OF 14q32 TRANSLOCATIONS IN MULTIPLE MYELOMA

scientific article published on 01 December 1998

Telomere length predicts for outcome to FCR chemotherapy in CLL

scientific article published on 30 January 2019

Thalidomide maintenance following high-dose therapy in multiple myeloma: a UK myeloma forum phase 2 study

scientific article published in November 2007

The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells

scientific article published on 5 December 2014

The PNH phenotype cells that emerge in most patients after CAMPATH-1H therapy are present prior to treatment.

scientific article published in October 1999

The biological and clinical relationship between CD5+23+ monoclonal B-cell lymphocytosis and chronic lymphocytic leukaemia

scientific article published on December 2007

The bone marrow microenvironment influences the differential chemokine receptor expression of normal and neoplastic plasma cells

scientific article published on 01 June 2005

The impact of attaining a minimal disease state after high-dose melphalan and autologous transplantation for multiple myeloma

scientific article published in March 2001

The interleukin-6 receptor alpha-chain (CD126) is expressed by neoplastic but not normal plasma cells.

scientific article published in December 2000

Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma

article

Translocation t(11;14) in multiple myeloma: Analysis of translocation breakpoints on der(11) and der(14) chromosomes suggests complex molecular mechanisms of recombination

scientific article published in February 2004

Translocation t(14;16) in IgM multiple myeloma

scientific article published on 18 April 2011

p53 gene mutations in multiple myeloma.

scientific article

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