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List of works by Erwan Bezard

A Phase 2A Trial of the Novel mGluR5-Negative Allosteric Modulator Dipraglurant for Levodopa-Induced Dyskinesia in Parkinson's Disease

scientific article

A brain-spine interface alleviating gait deficits after spinal cord injury in primates

scientific article

A call for clinically driven experimental design in assessing neuroprotection in experimental Parkinsonism

scientific article published on 01 September 2006

A chronic MPTP model reproducing the slow evolution of Parkinson's disease: evolution of motor symptoms in the monkey

scientific article published in August 1997

A critique of available scales and presentation of the Non-Human Primate Dyskinesia Rating Scale

scientific article published on 13 September 2012

A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys

scientific article

A new cerebral hemorrhage model in cynomolgus macaques created by injection of autologous anticoagulated blood into the brain

scientific article published on 20 May 2011

A preclinical study on the combined effects of repeated eltoprazine and preladenant treatment for alleviating L-DOPA-induced dyskinesia in Parkinson's disease.

scientific article

Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and l-DOPA-induced dyskinesia

scientific article published on 19 October 2013

Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.

scientific article

Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice

scientific article published on 10 February 2006

Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse

scientific article

Age-dependent α-synuclein aggregation in the Microcebus murinus lemur primate

scientific article

Alpha-synuclein propagation: New insights from animal models

scientific article published on 08 September 2015

Alterations in Functional Cortical Hierarchy in Hemiparkinsonian Rats.

scientific article

Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease

scientific article

Altered D(1) dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates.

scientific article published on 9 February 2007

Altered pallido-pallidal synaptic transmission leads to aberrant firing of globus pallidus neurons in a rat model of Parkinson's disease.

scientific article published on 13 August 2012

An evaluation of istradefylline treatment on Parkinsonian motor and cognitive deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque models

scientific article published on 13 July 2016

An mGlu4-Positive Allosteric Modulator Alleviates Parkinsonism in Primates

scientific article published on 14 September 2018

Animal models of Parkinson's disease: limits and relevance to neuroprotection studies.

scientific article

Animal models of parkinsonism

scientific article published in October 2005

Antagonizing L-type Ca2+ channel reduces development of abnormal involuntary movement in the rat model of L-3,4-dihydroxyphenylalanine-induced dyskinesia.

scientific article

Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia

scientific article published on 14 October 2013

Antidyskinetic effect of A2A and 5HT1A/1B receptor ligands in two animal models of Parkinson's disease

scientific article

Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology?

scientific article

Asymmetrically lesioned mesencephalon in healthy rodents: call for caution

scientific article

Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function

scientific article published on 12 May 2003

Basal Ganglia circuits underlying the pathophysiology of levodopa-induced dyskinesia.

scientific article

Behavioural profiles in captive-bred cynomolgus macaques: towards monkey models of mental disorders?

scientific article

Blood withdrawal affects iron store dynamics in primates with consequences on monoaminergic system function.

scientific article published on 4 February 2015

Brain-derived neurotrophic factor and the plasticity of the mesolimbic dopamine pathway

scientific article published on January 2004

Brain-derived neurotrophic factor controls dopamine D3 receptor expression: therapeutic implications in Parkinson's disease.

scientific article published on November 2003

CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease

scientific article published on 28 September 2020

Cardinal Motor Features of Parkinson's Disease Coexist with Peak-Dose Choreic-Type Drug-Induced Dyskinesia.

scientific article

Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders.

scientific article published on December 2009

Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia

scientific article

Combined fenobam and amantadine treatment promotes robust antidyskinetic effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's disease

scientific article published on 7 March 2014

Comparison of eight clinical rating scales used for the assessment of MPTP-induced parkinsonism in the Macaque monkey

scientific article published on 01 March 2000

Compensatory effects of glutamatergic inputs to the substantia nigra pars compacta in experimental parkinsonism

scientific article published in November 1997

Compensatory mechanisms in experimental and human parkinsonism: towards a dynamic approach

scientific article published on 01 June 1998

Compensatory regulation of striatal neuropeptide gene expression occurs before changes in metabolic activity of basal ganglia nuclei.

scientific article published in June 2003

Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging

scientific article published on 23 September 2019

Configuration of electrical spinal cord stimulation through real-time processing of gait kinematics

scientific article published on 01 September 2018

Contribution of pre-synaptic mechanisms to L-DOPA-induced dyskinesia.

scientific article

Coordinated reset has sustained aftereffects in Parkinsonian monkeys

scientific article published in November 2012

Cortical stimulation and epileptic seizure: a study of the potential risk in primates

scientific article published in August 1999

Could the serotonin theory give rise to a treatment for levodopa-induced dyskinesia in Parkinson's disease?

scientific article published on 10 February 2015

D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly

scientific article published on 10 March 2015

D1 dopamine receptor-mediated LTP at GABA synapses encodes motivation to self-administer cocaine in rats

scientific article

D1 receptor agonist improves sleep-wake parameters in experimental parkinsonism.

scientific article

Decreased Rhes mRNA levels in the brain of patients with Parkinson's disease and MPTP-treated macaques

scientific article

Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease

scientific article

Differential behavioral effects of partial bilateral lesions of ventral tegmental area or substantia nigra pars compacta in rats

scientific article

Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections

scientific article

Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesia

scientific article

Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys

scientific article

Dopamine-dependent long-term depression at subthalamo-nigral synapses is lost in experimental parkinsonism

scientific article published on September 2013

Double-dissociation of the catecholaminergic modulation of synaptic transmission in the oval bed nucleus of the stria terminalis.

scientific article

Down-regulating α-synuclein for treating synucleopathies

scientific article

Early prenatal exposure to MPTP does not affect nigrostrial neurons in macaque monkey

scientific article published on 19 November 2015

Effect of serotonin transporter blockade on L-DOPA-induced dyskinesia in animal models of Parkinson's disease

scientific article published on 20 April 2015

Effect of the D3 dopamine receptor partial agonist BP897 [N-[4-(4-(2-methoxyphenyl)piperazinyl)butyl]-2-naphthamide] on L-3,4-dihydroxyphenylalanine-induced dyskinesias and parkinsonism in squirrel monkeys.

scientific article

Effect of the alpha 2 adrenoreceptor antagonist, idazoxan, on motor disabilities in MPTP-treated monkey

scientific article published on 01 October 1999

Effects of L-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey

scientific article published on March 1998

Effects of L-tryptophan on L-DOPA-induced dyskinesia in the L-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque model of Parkinson's disease

scientific article published on 23 February 2014

Effects of memantine and galantamine on cognitive performance in aged rhesus macaques ⬇️

scientific article published on November 15, 2012

Effects of riluzole on the electrophysiological activity of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey

scientific article published on March 2000

Electrophysiological and metabolic evidence that high‐frequency stimulation of the subthalamic nucleus bridles neuronal activity in the subthalamic nucleus and the substantia nigra reticulata ⬇️

scientific article published on October 1, 2003

Endogenous morphine-like compound immunoreactivity increases in parkinsonism

scientific article published on 8 July 2011

Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity

scientific article published on 10 January 2017

Enhanced preproenkephalin-B-derived opioid transmission in striatum and subthalamic nucleus converges upon globus pallidus internalis in L-3,4-dihydroxyphenylalanine-induced dyskinesia.

scientific article published in September 2006

Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors.

scientific article

Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates

scientific article published on 11 May 2020

Exosomes, an Unmasked Culprit in Neurodegenerative Diseases.

scientific article published on 31 January 2017

Experimental animal models of Parkinson's disease: A transition from assessing symptomatology to α-synuclein targeted disease modification.

scientific article published on 29 July 2017

Experimental models of Parkinson's disease: from the static to the dynamic

scientific article published on 01 January 1998

Experimental reappraisal of continuous dopaminergic stimulation against L-dopa-induced dyskinesia

scientific article published on 09 November 2012

From experimentation to the surgical treatment of Parkinson's disease: prelude or suite in basal ganglia research?

scientific article

Functional connectivity in human and monkey brain: new insights for understanding movement disorders?

scientific article published in January 2012

G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice

scientific article published on 30 August 2018

Gastrointestinal and metabolic function in the MPTP-treated macaque model of Parkinson's disease

scientific article published on 23 December 2020

Genes regulated in MPTP-treated macaques and human Parkinson's disease suggest a common signature in prefrontal cortex.

scientific article published on 2 March 2010

Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease.

scientific article published on 21 January 2016

Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration.

scientific article published on 17 May 2017

Glutamatergic compensatory mechanisms in experimental parkinsonism

scientific article published in May 1998

Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-Related Neurodegenerative Diseases

scientific article published on 27 November 2018

Harnessing the trophic and modulatory potential of statins in a dopaminergic cell line

scientific article published on 22 December 2015

High frequency stimulation of the entopeduncular nucleus has no effect on striatal dopaminergic transmission

scientific article published in March 2004

High frequency stimulation of the entopeduncular nucleus sets the cortico-basal ganglia network to a new functional state in the dystonic hamster

scientific article

High frequency stimulation of the internal Globus Pallidus (GPi) simultaneously improves parkinsonian symptoms and reduces the firing frequency of GPi neurons in the MPTP-treated monkey

scientific article published in August 1996

High-frequency stimulation of both zona incerta and subthalamic nucleus induces a similar normalization of basal ganglia metabolic activity in experimental parkinsonism

scientific article

IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP.

scientific article published on 3 April 2008

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates

scientific article published on 13 May 2020

Immediate-early gene expression in structures outside the basal ganglia is associated to l-DOPA-induced dyskinesia

scientific article published on 6 October 2013

Impact of chronic subthalamic high-frequency stimulation on metabolic basal ganglia activity: a 2-deoxyglucose uptake and cytochrome oxidase mRNA study in a macaque model of Parkinson's disease

scientific article

Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease: an update.

scientific article published on 15 February 2017

In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson's disease.

scientific article published on 30 August 2017

In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains.

scientific article published on 11 April 2017

Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.

scientific article published in January 2005

Increased slow oscillatory activity in substantia nigra pars reticulata triggers abnormal involuntary movements in the 6-OHDA-lesioned rat in the presence of excessive extracellular striatal dopamine

scientific article published on 10 March 2006

Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice

scientific article published on 08 January 2020

Inhaling xenon ameliorates l-dopa-induced dyskinesia in experimental parkinsonism

scholarly article by Jérôme Baufreton et al published October 2018 in Movement Disorders

Inhibiting Lateral Habenula Improves L-DOPA-Induced Dyskinesia.

scientific article published on 9 September 2014

Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms.

scientific article

Insulin resistance and exendin-4 treatment for multiple system atrophy.

scientific article published on 14 March 2017

Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification?

scientific article published on 28 February 2014

Intra-axonal protein aggregation in the peripheral nervous system

scientific article published on 01 March 2014

Intrastriatal injection of alpha-synuclein fibrils induces Parkinson-like pathology in macaques

scientific article published on 01 November 2019

Intratelencephalic corticostriatal neurons equally excite striatonigral and striatopallidal neurons and their discharge activity is selectively reduced in experimental parkinsonism

scientific article published in May 2008

Investigating the receptor-independent neuroprotective mechanisms of nicotine in mitochondria

scientific article published on 27 June 2005

Involvement of canonical and non-canonical D1 dopamine receptor signalling pathways in L-dopa-induced dyskinesia.

scientific article published on December 2009

Involvement of sensorimotor, limbic, and associative basal ganglia domains in L-3,4-dihydroxyphenylalanine-induced dyskinesia.

scientific article

Involvement of the bed nucleus of the stria terminalis in L-Dopa induced dyskinesia

scientific article

Involvement of the subthalamic nucleus in glutamatergic compensatory mechanisms

scientific article published in June 1999

Is near-infrared light neuroprotective?

scientific article

Kinetics of nigral degeneration in a chronic model of MPTP-treated mice

scientific article published on September 1997

L-DOPA Impairs Proteasome Activity in Parkinsonism through D1 Dopamine Receptor

scientific article published on 01 January 2012

L-DOPA regulates α-synuclein accumulation in experimental parkinsonism

scientific article published on 04 December 2020

L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain

scientific article

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum

scientific article published on 16 January 2014

LC-MS/MS-based quantification of kynurenine metabolites, tryptophan, monoamines and neopterin in plasma, cerebrospinal fluid and brain

scientific article

Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.

scientific article

Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model

scientific article published on 04 April 2017

Levetiracetam Interferes With the L-dopa priming process in MPTP-lesioned drug-naive marmosets

scientific article

Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque

scientific article published in February 2004

Levetiracetam potentiates the antidyskinetic action of amantadine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's disease

scientific article published on 5 March 2004

Levodopa gains psychostimulant-like properties after nigral dopaminergic loss

scientific article published in July 2013

Levodopa improves motor deficits but can further disrupt cognition in a macaque Parkinson model

scientific article published on 12 December 2012

Levodopa-induced dyskinesia in MPTP-treated macaques is not dependent on the extent and pattern of nigrostrial lesioning.

scientific article published in July 2005

Levodopa-induced dyskinesia in Parkinson disease: Current and Evolving Concepts

scientific article published on 30 November 2018

Levodopa-induced dyskinesias in the absence of nigrostriatal degeneration

scientific article published on 20 June 2013

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.

scientific article published on 18 February 2014

Local transgene expression and whole-body transgenesis to model brain diseases in nonhuman primate

scientific article published on 29 January 2019

Localization of endogenous morphine-like compounds in the mouse spinal cord

scientific article published on 01 May 2012

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.

scientific article

Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove

scientific journal article

Lysosomal impairment in Parkinson's disease

scientific article published on 11 April 2013

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

scientific article

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia

scientific article published on November 2015

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia

article by Weixing Shen et al published 1 June 2016 in Neuron

Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia.

scientific article published on November 2010

Meta-analysis of amantadine efficacy for improving preclinical research reliability

scientific article published on 04 October 2018

Metabolic activity of the subthalamic nucleus in a primate model of L-dopa-unresponsive parkinsonism.

scientific article published on 31 August 2010

Microarray analysis of nonhuman primates: validation of experimental models in neurological disorders

scientific article published on 5 March 2003

Microdialysis in awake macaque monkeys for central nervous system pharmacokinetics

scientific article published on 04 December 2018

Migration and differentiation of human mesenchymal stem cells in the normal rat brain

scientific article

Misrepresentation of neuroscience data might give rise to misleading conclusions in the media: the case of attention deficit hyperactivity disorder

scientific article

MitoBrain, Putting energy into the brain

scientific article published in June 2016

Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson's disease.

scientific article published on 8 August 2017

Modeling Parkinson's disease in primates: The MPTP model

scientific article published on March 2012

Models of hyperkinetic disorders in primates

scientific article published on 16 December 2019

Molecular mechanisms of l-DOPA-induced dyskinesia.

scientific article published on January 2011

Multi-facetted impulsivity following nigral degeneration and dopamine replacement therapy

scientific article

Multiple system atrophy: a prototypical synucleinopathy for disease-modifying therapeutic strategies.

scientific article published on 12 April 2014

NMDA receptor GluN2D subunit participates to levodopa-induced dyskinesia pathophysiology

scientific article published on 24 September 2018

Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases

scientific article published on 13 January 2016

Nanoscale exploration of the extracellular space in the live brain by combining single carbon nanotube tracking and super-resolution imaging analysis

scientific article published on 09 March 2019

Neuroanatomical study of the A11 diencephalospinal pathway in the non-human primate

scientific article (publication date: 13 October 2010)

Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism.

scientific article

Neurological drug development: a guide for a start-up biotech

scientific article published on 15 August 2013

Neuroprotection for Parkinson's disease: a call for clinically driven experimental design

scientific article published on 01 July 2003

Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment

scientific article published on 01 January 2004

Neuroprotective effects of rotigotine in the acute MPTP-lesioned mouse model of Parkinson's disease

scientific article published on 8 December 2007

Neuroprotective strategies for Parkinson's disease: conceptual limits of animal models and clinical trials.

scientific article published on May 2004

New animal models of Parkinson's disease ⬇️

scientific article published on June 1, 2011

Nociceptin/Orphanin FQ Receptor Agonists Attenuate L-DOPA-Induced Dyskinesias

scientific article published on 01 November 2012

Noradrenergic modulation of subthalamic nucleus activity: behavioral and electrophysiological evidence in intact and 6-hydroxydopamine-lesioned rats

scientific article published on 01 September 2007

Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: a proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGE

scientific article

Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by L-dopa and ropinirole in the MPTP-lesioned marmoset

scientific article published in November 2003

Novel pharmacological targets for the treatment of Parkinson's disease

scientific article published on October 2006

Novel self-replicating α-synuclein polymorphs that escape ThT monitoring can spontaneously emerge and acutely spread in neurons

scientific article published on 02 October 2020

Oral ambroxol increases brain glucocerebrosidase activity in a nonhuman primate.

scientific article

Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy

scientific article published on 29 October 2020

PSD-95 expression controls L-DOPA dyskinesia through dopamine D1 receptor trafficking

scientific article

Pallidal border cells: an anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey

scientific article

Partial bilateral mesencephalic lesions affect D1 but not D2 binding in both the striatum and cortex

scientific article published in December 2004

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

scientific article published in September 2017

Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors.

scientific article

Pathophysiology and therapy of L-Dopa-induced dyskinesia

scientific article published in December 2003

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

scientific article published on 21 July 2015

Pattern of levodopa-induced striatal changes is different in normal and MPTP-lesioned mice.

scientific article published on March 2003

Permeability of blood-brain barrier in macaque model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson disease

scientific article published on 21 January 2016

Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson's Disease Models

scientific article published in February 2018

Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of L-DOPA-induced dyskinesia

scientific article

Phenotype of striatofugal medium spiny neurons in parkinsonian and dyskinetic nonhuman primates: a call for a reappraisal of the functional organization of the basal ganglia.

scientific article

Premotor parkinsonism models.

scientific article published on January 2014

Presymptomatic diagnosis of experimental Parkinsonism with 123I-PE2I SPECT.

scientific article published on July 2003

Presymptomatic revelation of experimental parkinsonism.

scholarly article by Erwan Bezard et al published 20 January 1997 in NeuroReport

Priorities in Parkinson's disease research

scientific article published on May 2011

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

scientific article published on 17 August 2018

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates.

scientific article published in August 2015

Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway

scientific article

Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson's disease through inhibition of ROS-NO pathway

scientific article

Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies

scientific article published on 21 July 2015

Protein aggregation in the aging retina.

scientific article

Prototypic and arkypallidal neurons in the dopamine-intact external globus pallidus

scientific article published on April 2015

Quantification of dopamine transporter by 123I-PE2I SPECT and the noninvasive Logan graphical method in Parkinson's disease

scientific article published in May 2003

RGS4 is involved in the generation of abnormal involuntary movements in the unilateral 6-OHDA-lesioned rat model of Parkinson's disease.

scientific article

RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease.

scientific article published in December 2007

RGS9-2 rescues dopamine D2 receptor levels and signaling in dystonia mouse models

scientific article published on 01 January 2019

Rabphilin 3A: A novel target for the treatment of levodopa-induced dyskinesias.

scientific article published on 17 August 2017

RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease

scientific article published on 01 May 2020

Ratio of inhibited-to-activated pallidal neurons decreases dramatically during passive limb movement in the MPTP-treated monkey

scientific article published on March 2000

Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy

scientific article published on August 2016

Reinforcing properties of Pramipexole in normal and parkinsonian rats

scientific article published on 23 August 2012

Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.

scientific article published in September 2001

Riluzole delayed appearance of parkinsonian motor abnormalities in a chronic MPTP monkey model

scientific article published on 01 September 1998

Rise and fall of minocycline in neuroprotection: need to promote publication of negative results

scientific article

Rotigotine treatment partially protects from MPTP toxicity in a progressive macaque model of Parkinson's disease

scientific article published on 12 October 2006

Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.

scientific article published on 15 July 2014

Shaping of motor responses by incentive values through the basal ganglia.

scientific article

Simvastatin decreases levodopa-induced dyskinesia in monkeys, but not in a randomized, placebo-controlled, multiple cross-over ("n-of-1") exploratory trial of simvastatin against levodopa-induced dyskinesia in Parkinson's disease patients.

scientific article

Single-molecule imaging of the functional crosstalk between surface NMDA and dopamine D1 receptors.

scientific article published on 14 October 2013

Sleep disorders in Parkinson's disease: the contribution of the MPTP non-human primate model.

scientific article published on 25 July 2009

Sonic hedgehog is a neuromodulator in the adult subthalamic nucleus.

scientific article published on 2 October 2003

Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury

scientific article

Spontaneous long-term compensatory dopaminergic sprouting in MPTP-treated mice

scientific article

Striatal NELF-mediated RNA polymerase II stalling controls L-dopa induced dyskinesia.

scientific article published on 16 October 2015

Striatal histone modifications in models of levodopa-induced dyskinesia

scientific article

Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease

scientific article

Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure.

scientific article

Structures outside the basal ganglia may compensate for dopamine loss in the presymptomatic stages of Parkinson's disease.

scientific article published in April 2001

Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia

scientific article published on 6 February 2013

Subthalamic stimulation elicits hemiballismus in normal monkey

scientific article published in May 1997

Subthalamic stimulation increases striatal tyrosine hydroxylase phosphorylation

scientific article

Synaptic recruitment of AMPA glutamate receptor subunits in levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate.

scientific article published in February 2010

Synaptic regulator α-synuclein in dopaminergic fibers is essentially required for the maintenance of subependymal neural stem cells.

scientific article published on 6 December 2017

Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

scientific article published on 10 July 2020

Systemic Gene Delivery by Single-Dose Intracardiac Administration of scAAV2/9 and scAAV2/rh10 Variants in Newborn Rats

article

Systemic gene delivery to the central nervous system using Adeno-associated virus

scientific article

Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques.

scientific article published on 9 February 2012

TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates

scientific article published on 17 December 2018

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

scientific article published on 03 June 2015

Targeting α-synuclein: Therapeutic options

scientific article published on March 2016

Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease

scientific article

Temporal and spatial alterations in GPi neuronal encoding might contribute to slow down movement in Parkinsonian monkeys.

scientific article

The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson's disease

scientific article published in April 2008

The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline

scientific article published on 21 March 2018

The deafferented nonhuman primate is not a reliable model of intractable pain

scientific article published on 01 March 2003

The expression of cannabinoid type 1 receptor and 2-arachidonoyl glycerol synthesizing/degrading enzymes is altered in basal ganglia during the active phase of levodopa-induced dyskinesia

scientific article published on 21 June 2018

The hidden side of Parkinson's disease: studying pain, anxiety and depression in animal models

scientific article published on 23 October 2018

The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson's disease patients

scientific article published on 20 June 2019

The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model

scientific article published on 27 May 2014

The nigrostriatal pathway in Creutzfeldt-Jakob disease.

scientific article published in July 2009

The pathologic features of neurocutaneous melanosis in a cynomolgus macaque

scientific article published on 9 March 2009

The translational value of the MPTP non-human primate model of Parkinsonism for deep brain stimulation research

scientific article published on January 2011

The vascular endothelial cell is a new origin of melanin pigment on cynomolgus macaque with neurocutaneous melanosis

scientific article published on 01 December 2008

Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease

scientific article published on December 2003

Toward a primate model of L-dopa-unresponsive parkinsonism mimicking striatonigral degeneration

scientific article published on 01 May 2000

Toward an animal model of restless legs syndrome?

scientific article published on 30 January 2012

Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies

scientific article published on 22 August 2019

Treating Parkinson's disease: preserve the spines! (Commentary on Soderstrom et al.).

scientific article published on 25 January 2010

U18666A, an activator of sterol regulatory element binding protein pathway, modulates presynaptic dopaminergic phenotype of SH-SY5Y neuroblastoma cells

scientific article published on 13 April 2017

Unexpected toxicity of very low dose MPTP in mice: A clue to the etiology of Parkinson's disease?

scientific article published on 01 December 2015

Unraveling substantia nigra sequential gene expression in a progressive MPTP-lesioned macaque model of Parkinson's disease

scientific article published in October 2005

Upregulation of striatal preproenkephalin gene expression occurs before the appearance of parkinsonian signs in 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine monkeys

scientific article

Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates

scientific article published on 18 May 2020

Viral-mediated oligodendroglial alpha-synuclein expression models multiple system atrophy

scientific article published on 29 May 2017

What should be said to the lay public regarding ADHD etiology

scientific article published on 31 August 2011

Why bother using non-human primate models of cognitive disorders in translational research?

scientific article published on 29 June 2015

Widespread Monoaminergic Dysregulation of Both Motor and Non-Motor Circuits in Parkinsonism and Dyskinesia

scientific article published on 25 April 2014

Wireless neurosensor for full-spectrum electrophysiology recordings during free behavior

scientific article published on 4 December 2014

[GRK6, a new therapeutic approach to alleviate L-dopa-induced dyskinesia].

scientific article

[L-dopa induced dyskinesia in Parkinson's disease]

scientific article published in February 2015

[PSD-95 expression controls L-Dopa dyskinesia].

scientific article published on 28 February 2013

[Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure]

scientific article published on 01 April 2008

µ opioid receptor agonism for L-DOPA-induced dyskinesia in Parkinson's disease

scientific article published on 20 July 2020

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