List of works by Valerio Pazienza

16S rRNA gene sequencing of rectal swab in patients affected by COVID-19

scientific article published on 17 February 2021

A randomized controlled trial of pegylated interferon alpha-2a (40 KD) or interferon alpha-2a plus ribavirin and amantadine vs interferon alpha-2a and ribavirin in treatment-naïve patients with chronic hepatitis C.

scientific article published in May 2005

ARNTL2 and SERPINE1: potential biomarkers for tumor aggressiveness in colorectal cancer.

scientific article

Advance in molecular diagnostic tools for hepatitis B virus detection

scientific article published on September 2013

Affinity analysis of differentially expressed genes in hepatocytes expressing HCV core genotype 1b or 3a.

scientific article published on 3 June 2013

Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans

scientific article published on 18 August 2015

Alteration of circadian rhythmicity of CD3+CD4+ lymphocyte subpopulation in healthy aging

scientific article published on 01 July 2011

Alteration of hypothalamic-pituitary-thyroid axis function in non-small-cell lung cancer patients.

scientific article published on 23 August 2011

Altered expression of the clock gene machinery in kidney cancer patients

article

Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis

scientific article published on 6 March 2015

An in vitro model of hepatitis C virus genotype 3a-associated triglycerides accumulation

scientific article

Analysis of Gut Microbiota in Rheumatoid Arthritis Patients: Disease-Related Dysbiosis and Modifications Induced by Etanercept

scientific article published on 27 September 2018

Anti-correlation between longevity gene SirT1 and Notch signaling in ascending aorta biopsies from patients with bicuspid aortic valve disease

scientific article

Antiphase signalling in the neuroendocrine-immune system in healthy humans

scientific article published on 08 April 2011

Body site-dependent variations of microbiota in pancreatic cancer pathophysiology

scientific article published on 06 June 2019

CASR gene activating mutations in two families with autosomal dominant hypocalcemia

scientific article

Cancer sniffer dogs: how can we translate this peculiarity in laboratory medicine? Results of a pilot study on gastrointestinal cancers

scientific article published on 01 November 2017

Circadian aspects of growth hormone-insulin-like growth factor axis function in patients with lung cancer.

scientific article published on 19 May 2011

Circadian transcriptome analysis in human fibroblasts from Hunter syndrome and impact of iduronate-2-sulfatase treatment

scientific article

Clock gene expression in mouse kidney and testis: analysis of periodical and dynamical patterns.

scientific article published in April 2012

Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients.

scientific article published in December 2011

Clock genes-dependent acetylation of complex I sets rhythmic activity of mitochondrial OxPhos.

scientific article

Correction: Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma.

scientific article published on 22 March 2013

Correlations among PPARγ, DNMT1, and DNMT3B Expression Levels and Pancreatic Cancer

scientific article published on 8 August 2012

DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression

scientific article published on 15 January 2016

DNA methyltransferases 1 and 3b expression in Huh-7 cells expressing HCV core protein of different genotypes

scientific article published on 24 April 2012

Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome

scientific article published on 22 August 2019

Deregulated expression of cryptochrome genes in human colorectal cancer

scientific article

Development of a metabolites risk score for one-year mortality risk prediction in pancreatic adenocarcinoma patients

scientific article published on February 2016

Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines

scientific article published on 18 May 2019

Differential patterns in the periodicity and dynamics of clock gene expression in mouse liver and stomach

scientific article published on 06 November 2012

Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma.

scientific article published on 11 August 2016

Engineered Resistant-Starch (ERS) Diet Shapes Colon Microbiota Profile in Parallel with the Retardation of Tumor Growth in In Vitro and In Vivo Pancreatic Cancer Models

scientific article

Epithelial-mesenchymal transition: molecular pathways of hepatitis viruses-induced hepatocellular carcinoma progression

scientific article published on 16 May 2014

Exploitation of host clock gene machinery by hepatitis viruses B and C.

scientific article published on December 2013

Exploring the Role of Gut Microbiota in Major Depressive Disorder and in Treatment Resistance to Antidepressants

scientific article published on 27 August 2020

Exploring the microbiota to better understand gastrointestinal cancers physiology.

scientific article

Fasting cycles potentiate the efficacy of gemcitabine treatment in in vitro and in vivo pancreatic cancer models.

scientific article

Fasting inhibits hepatic stellate cells activation and potentiates anti-cancer activity of Sorafenib in hepatocellular cancer cells.

scientific article

Functional Impact of Autophagy-Related Genes on the Homeostasis and Dynamics of Pancreatic Cancer Cell Lines

scientific article published on May 2015

Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk

scientific article published on 29 July 2016

Gene expression profile of Huh-7 cells expressing hepatitis C virus genotype 1b or 3a core proteins

scientific article published on 18 September 2008

Genetic ablation of macrohistone H2A1 leads to increased leanness, glucose tolerance and energy expenditure in mice fed a high-fat diet

scientific article

Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma

scientific article published on 07 February 2019

Gut Dysbiosis and Adaptive Immune Response in Diet-induced Obesity vs. Systemic Inflammation.

scientific article published on 22 June 2017

Gut Microbiota Profiles Differ among Individuals Depending on Their Region of Origin: An Italian Pilot Study

scientific article published on 23 October 2019

Hepatitis C virus core protein genotype 3a increases SOCS-7 expression through PPAR-{gamma} in Huh-7 cells

scientific article published on 31 March 2010

Hepatitis C virus, mitochondria and auto/mitophagy: exploiting a host defense mechanism

scientific article published on March 2014

Hepatitis delta virus induces specific DNA methylation processes in Huh-7 liver cancer cells

scientific article published on 21 March 2013

Hepatitis delta virus inhibits alpha interferon signaling

scientific article

Hepatitis viruses exploitation of host DNA methyltransferases functions

scientific article published on 07 July 2015

High Levels of Prebiotic Resistant Starch in Diet Modulate Gene Expression and Metabolomic Profile in Pancreatic Cancer Xenograft Mice.

scientific article

High Levels of Prebiotic Resistant Starch in Diet Modulate a Specific Pattern of miRNAs Expression Profile Associated to a Better Overall Survival in Pancreatic Cancer

scientific article published on 29 December 2020

High RAD51 mRNA expression characterize estrogen receptor-positive/progesteron receptor-negative breast cancer and is associated with patient's outcome

scientific article

Histone variants and lipid metabolism

scientific article

Hypermethylated levels of E-cadherin promoter in Huh-7 cells expressing the HCV core protein

scientific article published on 27 May 2011

Hypothalamus-hypophysis-thyroid axis function in healthy aging.

scientific article published on October 2010

IL-10 haplotypes as possible predictors of spontaneous clearance of HCV infection

scientific article published on February 2004

Identification and functional characterization of three NoLS (nucleolar localisation signals) mutations of the CDC73 gene

scientific article

Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma

scientific article published in 2013

Impact of Different Types of Diet on Gut Microbiota Profiles and Cancer Prevention and Treatment

scientific article published on 29 March 2019

Impact of HCV genetic differences on pathobiology of disease.

scientific article published on September 2011

Impact of Mediterranean Diet on Disease Activity and Gut Microbiota Composition of Rheumatoid Arthritis Patients

scientific article published on 14 December 2020

In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease

scientific article published on 5 December 2006

Influence of gemcitabine chemotherapy on the microbiota of pancreatic cancer xenografted mice

scientific article published on 22 February 2018

Inhibition of pyruvate dehydrogenase kinase influence microbiota and metabolomic profile in pancreatic cancer xenograft mice

scientific article published on 18 November 2020

Interplay between SOX9, β-catenin and PPARγ activation in colorectal cancer.

scientific article published on 11 April 2013

Metabolomic profile in pancreatic cancer patients: a consensus-based approach to identify highly discriminating metabolites

scientific article published on 31 December 2015

MicroRNA co-expression networks exhibit increased complexity in pancreatic ductal compared to Vater's papilla adenocarcinoma.

scientific article

Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes

scientific article published on 11 June 2007

Mirna expression profiles identify drivers in colorectal and pancreatic cancers.

scientific article

Modeling interactions between Human Equilibrative Nucleoside Transporter-1 and other factors involved in the response to gemcitabine treatment to predict clinical outcomes in pancreatic ductal adenocarcinoma patients.

scientific article

Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes

scientific article

Mutual antagonism between circadian protein period 2 and hepatitis C virus replication in hepatocytes

scientific article

Neuro-endocrine correlations of hypothalamic-pituitary-thyroid axis in healthy humans.

scientific article published in April 2011

Non-alcoholic fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms

scientific article

Ophthalmological complications in hepatitis C virus infection: side effect of interferon therapy or a direct role of HCV?

scientific article published on 30 May 2011

PPARs Signaling and Cancer in the Gastrointestinal System

scientific article published on 17 September 2012

PPARs and Gastrointestinal Cancer

scientific article published on 14 November 2012

Peroxisome proliferator-activated receptor-alpha and -gamma mRNA levels are reduced in chronic hepatitis C with steatosis and genotype 3 infection

scientific article published in January 2006

Pharmacomicrobiomics: exploiting the drug-microbiota interactions in anticancer therapies.

scientific article

Probiotic Bifidobacterium lactis, anti-oxidant vitamin E/C and anti-inflammatory dha attenuate lung inflammation due to pm2.5 exposure in mice

scientific article published on 10 December 2018

REV-ERBα and the clock gene machinery in mouse peripheral tissues: a possible role as a synchronizing hinge.

scientific article published in April 2012

Real-time multiplex PCR assay to quantify hepatitis C virus RNA in peripheral blood mononuclear cells

scientific article published on 27 December 2005

Redox homeostasis and epigenetics in non-alcoholic fatty liver disease (NAFLD).

scientific article published on January 2013

Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: a meta-analysis of individual patient data.

scientific article

Rewiring carbohydrate catabolism differentially affects survival of pancreatic cancer cell lines with diverse metabolic profiles

scientific article

SIRT1 and circadian gene expression in pancreatic ductal adenocarcinoma: Effect of starvation.

scientific article

SIRT1 and the clock gene machinery in colorectal cancer.

scientific article

SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation

scientific article published on January 2014

Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings

scientific article published on 21 September 2016

Stage dependent destructuration of neuro-endocrine-immune system components in lung cancer patients

scientific article published on 29 December 2010

Sympathetic nervous system catecholamines and neuropeptide Y neurotransmitters are upregulated in human NAFLD and modulate the fibrogenic function of hepatic stellate cells

scientific article

Targeting human equilibrative nucleoside analog transporter (hENT1) expression through modified low glycemic index diet in pancreatic cancer

scientific article published on 02 May 2014

The TRPA1 channel is a cardiac target of mIGF-1/SIRT1 signaling

scientific article published on 8 August 2014

The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms

scientific article published on May 2007

The transcriptional regulators, the immune system and the the circadian clock

scientific article published on 01 January 2013

Time-Qualified Patterns of Variation of PPARγ, DNMT1, and DNMT3B Expression in Pancreatic Cancer Cell Lines.

scientific article published on 26 August 2012

Time-related dynamics of variation in core clock gene expression levels in tissues relevant to the immune system.

scientific article published in October 2011

Viral clearance in HCV viraemic patients with normal alanine aminotransferase after combination therapy: a controlled, open-labelled study

scientific article published in February 2004

mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart.

scientific article

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