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List of works by Sandra Demaria

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

scientific article published on 21 July 2021

Abstract 633: Inhibition of TGFβ as a strategy to convert the irradiated tumor into in situ individualized vaccine

Activin A promotes regulatory T cell-mediated immunosuppression in irradiated breast cancer

scientific article published on 22 October 2020

Aggressive Mammary Cancers Lacking Lymphocytic Infiltration Arise in Irradiated Mice and Can Be Prevented by Dietary Intervention

scientific article published on 12 December 2019

An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer.

scientific article published on December 2013

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials

scientific article published on 12 May 2020

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Ca

scientific article published on 2 August 2017

Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in I

scientific article published in September 2017

Barriers to Radiation-Induced In Situ Tumor Vaccination.

scientific article published on 13 March 2017

Baseline T cell dysfunction by single cell network profiling in metastatic breast cancer patients

scientific article published on 11 July 2019

Bathophenanthroline Disulfonate and Soluble CD4 as Probes for Early Events of HIV Type 1 Entry

article

CD73 Blockade Promotes Dendritic Cell Infiltration of Irradiated Tumors and Tumor Rejection

scientific article published on 11 February 2020

CD8 and beta 2-microglobulin-free MHC class I molecules in T cell immunoregulation

scientific article

CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy

scientific article published on 19 January 2016

Can abscopal effects of local radiotherapy be predicted by modeling T cell trafficking?

scientific article published on 17 May 2016

Cancer and inflammation: promise for biologic therapy.

scientific article

Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape.

scientific article

Clinical Trial Evidence of the Antitumor Activity of Topical Imiquimod for Breast Cancer Skin Metastases

scientific article published on 04 August 2014

Combination of radiotherapy and immune checkpoint inhibitors

scientific article

Combinations of immunotherapy and radiation in cancer therapy.

scientific article

Combining radiotherapy and cancer immunotherapy: a paradigm shift

scientific article

Combining radiotherapy and immunotherapy: a revived partnership

scientific article

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

scientific article published on 01 March 2020

Consensus guidelines for the detection of immunogenic cell death

scientific article published on October 2014

Converging focal radiation and immunotherapy in a preclinical model of triple negative breast cancer: contribution of VISTA blockade

scientific article published on 20 October 2020

Current clinical trials testing combinations of immunotherapy and radiation.

scientific article

Current clinical trials testing the combination of immunotherapy with radiotherapy.

scientific article

Cytosolic DNA Sensing in Organismal Tumor Control

scientific article published on 28 June 2018

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

scientific article

Defining the role of the immune system in cancer treatment: highlights from the Immunochemotherapy Conference ⬇️

scientific article published on June 1, 2011

Densely ionizing radiation acts via the microenvironment to promote aggressive Trp53-null mammary carcinomas

scientific article published on 10 October 2014

Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain

scientific article

Effects of Chemoradiation on Tumor-Host Interactions: The Immunologic Side

scientific article published on 01 March 2008

Emerging Opportunities and Challenges in Cancer Immunotherapy.

scientific article published on April 2016

Exercise in Regulation of Inflammation-Immune Axis Function in Cancer Initiation and Progression

scientific article

Exercise reduces immune suppression and breast cancer progression in a preclinical model

scientific article published on 28 January 2020

Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs

scholarly article by Julie M Diamond et al published August 2018 in Cancer immunology research

Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment

scientific article published on March 2013

Expression of cancer testis antigens in human BRCA-associated breast cancers: potential targets for immunoprevention?

scientific article published on 05 April 2011

Focal Irradiation And Systemic Transforming Growth Factor β Blockade in Metastatic Breast Cancer

scientific article published on 23 February 2018

Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody

scientific article published on 25 August 2009

Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016. ⬇️

scientific article published on 16 November 2017

Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.

scientific article

Future perspectives in melanoma research: meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014.

scientific article published on 30 November 2015

IL15 synergizes with radiotherapy to reprogram the tumor immune contexture through a dendritic cell connection

scientific article published on 09 July 2020

Immune induction strategies to enhance responses to PD-1 blockade: lessons from the TONIC trial

scientific article published on 21 November 2019

Immune recognition of irradiated cancer cells

scientific article published in November 2017

Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer

article

Immunogenic Cell Death Driven by Radiation-Impact on the Tumor Microenvironment

scientific article published on 01 January 2020

Immunogenic Subtypes of Breast Cancer Delineated by Gene Classifiers of Immune Responsiveness

scientific article published on 28 April 2016

Immunological Mechanisms Responsible for Radiation-Induced Abscopal Effect

scientific article published on 11 July 2018

Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts

scientific article published on 15 January 2018

In situ vaccination by radiotherapy to improve responses to anti-CTLA-4 treatment

scientific article published on 03 July 2015

Increased density of ecto 5' nucleotidase antigen on leukemic T cells from patients with cutaneous T-cell lymphoma and adult T-cell leukemia/lymphoma.

scientific article published in November 1989

Introduction to the Special BR-RIDGE Issue

scientific article published on 01 April 2010

Invariant NKT cells as novel targets for immunotherapy in solid tumors

scientific article

Invariant natural killer T cells regulate anti-tumor immunity by controlling the population of dendritic cells in tumor and draining lymph nodes

scientific article

Invariant natural killer T cells regulate breast cancer response to radiation and CTLA-4 blockade

scientific article

Local control by radiotherapy: is that all there is?

scientific article

Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial.

scientific article published on 18 June 2015

Mechanisms of synergy of radiotherapy and immunotherapy.

scientific article published on 15 January 2015

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

scientific article

Microarray analysis of miRNA expression profiles following whole body irradiation in a mouse model

scientific article published on 19 June 2018

Multilocular thymic cyst with follicular lymphoid hyperplasia in a male infected with HIV. A case report with fine needle aspiration cytology

article

PTEN at the interface of immune tolerance and tumor suppression.

scientific article published on 4 March 2017

Paclitaxel-induced apoptosis and mitotic arrest assessed by serial fine-needle aspiration: implications for early prediction of breast cancer response to neoadjuvant treatment

scientific article published on 01 December 2000

Peptide loading of nascent MHC class I molecules.

scientific article

Peptide-conformed beta2m-free class I heavy chains are intermediates in generation of soluble HLA by the membrane-bound metalloproteinase

scientific article

Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy)

scientific article published on 07 September 2020

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

scientific article published on 12 May 2020

Prognostic implications of residual disease tumor-infiltrating lymphocytes and residual cancer burden in triple negative breast cancer patients after neo-adjuvant chemotherapy

scientific article published on 01 February 2019

Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199.

scientific article

Radiation as an immunological adjuvant: current evidence on dose and fractionation.

scientific article

Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death

scientific article published on 25 April 2014

Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system.

scientific article published on 20 June 2019

Radiation therapy to convert the tumor into an in situ vaccine

scientific article published on November 2012

Radiation-Induced Long Noncoding RNAs in a Mouse Model after Whole-Body Irradiation

scientific article published on 8 January 2018

Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells.

scientific article published on September 2008

Radiation-induced adaptive response: new potential for cancer treatment

scientific article published on 17 June 2020

Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells.

scientific article published on 27 November 2017

Radiotherapy cooperates with IL15 to induce antitumor immune responses

scientific article published on 12 June 2020

Radiotherapy effects on anti-tumor immunity: implications for cancer treatment

scientific article

Radiotherapy enhances antitumor effect of anti-CD137 therapy in a mouse Glioma model

scientific article published on April 2010

Radiotherapy induces responses of lung cancer to CTLA-4 blockade

Radiotherapy: Changing the Game in Immunotherapy.

scientific article published on June 2016

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

scientific article published on 12 May 2020

Research Highlights: Immunotherapy

scientific article published on 01 September 2009

Results of a phase I-II study of adjuvant concurrent carboplatin and accelerated radiotherapy for triple negative breast cancer

scientific article published on 27 December 2016

Role of Local Radiation Therapy in Cancer Immunotherapy

scientific article published on 13 August 2015

Role of T lymphocytes in tumor response to radiotherapy

scientific article

Role of cell surface receptors in the regulation of non adaptive immune response by the large granular lymphocytes.

scientific article published on January 1988

Role of the Crosstalk Between CTLA-4 and NKG2D in the Development of Anti-CTLA-4 Treatment Strategies ⬇️

scientific article published on February 1, 2013

Select forms of tumor cell apoptosis induce dendritic cell maturation.

scientific article

Sensors of ionizing radiation effects on the immunological microenvironment of cancer

scientific article published on November 2007

Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule

scientific article published on 21 June 2016

Soluble CD4 induces the binding of human immunodeficiency virus type 1 to cells via the V3 loop of glycoprotein 120 and specific sites in glycoprotein 41.

scientific article published on March 1996

Soluble HLA proteins with bound peptides are released from the cell surface by the membrane metalloproteinase

scientific article

Soluble beta 2-microglobulin-free class I heavy chains are released from the surface of activated and leukemia cells by a metalloprotease

scientific article published in Journal of Biological Chemistry

Stromal Tumor-infiltrating Lymphocytes in NRG Oncology/NSABP B-31 Adjuvant Trial for Early-Stage HER2-Positive Breast Cancer

scientific article published on 01 August 2019

Subverting misconceptions about radiation therapy

scientific article published in March 2016

Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects

scientific article

Synergy of topical toll-like receptor 7 agonist with radiation and low-dose cyclophosphamide in a mouse model of cutaneous breast cancer

scientific article

Systemic effects of local radiotherapy

scientific article published on July 2009

TGFβ Is a Master Regulator of Radiation Therapy-Induced Antitumor Immunity

scientific article published on 9 April 2015

TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo.

scientific article published on 25 October 2011

TREX1 dictates the immune fate of irradiated cancer cells

scientific article published on 16 June 2017

The Future of Radiobiology.

scientific article published on 3 November 2017

The TLR7 agonist imiquimod as an adjuvant for radiotherapy-elicited in situ vaccination against breast cancer

scientific article published on 24 September 2013

The abscopal effect 67 years later: from a side story to center stage

scientific article published on 28 February 2020

The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas

scientific article published on August 2006

The convergence of radiation and immunogenic cell death signaling pathways.

scientific article

The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014.

scientific article published on 11 September 2014

The great debate at "Immunotherapy Bridge 2018", Naples, November 29th, 2018

scientific article published on 15 August 2019

The metalloproteinase-mediated pathway is essential for generation of soluble HLA class I proteins by activated cells in vitro: proposed mechanism for soluble HLA release in transplant rejection

scientific article published in July 1998

The need for a network to establish and validate predictive biomarkers in cancer immunotherapy

scientific article published on 3 November 2017

The numbers of FoxP3+ lymphocytes in sentinel lymph nodes of breast cancer patients correlate with primary tumor size but not nodal status

scientific article published on July 2011

The optimal partnership of radiation and immunotherapy: from preclinical studies to clinical translation

scientific article

The path to a better biomarker: Application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice

scientific article published on 04 March 2020

Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer

scientific article published on 5 July 2012

Towards precision radiotherapy for use with immune checkpoint blockers.

scientific article

Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod

scientific article published on 12 June 2019

Trial Watch: Immunotherapy plus radiation therapy for oncological indications

scientific article published on 25 July 2016

Trial watch: Immune checkpoint blockers for cancer therapy

scientific article published on 31 August 2017

Tumor infiltrating lymphocytes (TILs) improve prognosis in patients with triple negative breast cancer (TNBC).

scientific article

Tumor mutational burden is a determinant of immune-mediated survival in breast cancer

scientific article published on 30 July 2018

Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers

scientific article published on 16 January 2019

Understanding Responses to Stereotactic Body Radiotherapy and Pembrolizumab

article

Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group o

article by Maria Vittoria Dieci et al published October 2018 in Seminars in Cancer Biology

Using immunotherapy to boost the abscopal effect

scientific article published on 16 February 2018

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