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List of works by Tommaso Simoncini

"Controversial issues in climacteric medicine" series 3rd Pisa workshop "HRT in climacteric and aging brain". Pisa, Italy, 15-18 March 2003.

scientific article

17β-Estradiol inhibits vascular smooth muscle cell migration via up-regulation of striatin protein.

scientific article published on 29 July 2015

17β-estradiol attenuates atherosclerosis development: the possible role of hydrogen sulfide

scientific article published on 14 November 2012

17β-estradiol induces vasorelaxation by stimulating endothelial hydrogen sulfide release

scientific article published on 5 October 2012

2-methoxyestradiol induces vasodilation by stimulating NO release via PPARγ/PI3K/Akt pathway.

scientific article

A feasibility study on non-invasive fetal ECG to evaluate prenatal autonomic nervous system activity

scientific article published on 14 January 2020

A functioning FSH-secreting pituitary macroadenoma causing an ovarian hyperstimulation syndrome with multiple cysts resected and relapsed after leuprolide in a reproductive-aged woman.

scientific article

A review of the cardiovascular and breast actions of drospirenone in preclinical studies

scientific article published on February 2010

A three-dimensional organotypic culture of the human uterine exocervix for studying mucosal epithelial differentiation and migrating leukocytes

scientific article published on April 2004

Actin cytoskeleton remodelling by sex steroids in neurones.

scientific article published on January 2012

Activation of nitric oxide synthesis in human endothelial cells by red clover extracts.

scientific article published in January 2005

Activation of nitric oxide synthesis in human endothelial cells using nomegestrol acetate

scientific article published on 01 October 2006

Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

scientific article

Advanced Glycation End Products Activate Endothelium Through Signal-Transduction Receptor RAGE

scientific article published on 01 February 2002

Angiogenesis, inflammation and endothelial function in postmenopausal women screened for the metabolic syndrome

scientific article published on 07 February 2014

Anti-goat antibodies as a rare cause of high gonadotropin levels during menopausal transition

scientific article published on 17 June 2020

Are risk factors common to thyroid cancer and nodule? A forty years observational time-trend study

scientific article

Assessing the Long-Term Role of Vaccination against HPV after Loop Electrosurgical Excision Procedure (LEEP): A Propensity-Score Matched Comparison

scientific article published on 01 December 2020

Assessment of insomnia and related risk factors in postmenopausal women screened for the metabolic syndrome.

scientific article published on 22 November 2012

Circulating leptin, resistin, adiponectin, visfatin, adipsin and ghrelin levels and insulin resistance in postmenopausal women with and without the metabolic syndrome

scientific article published on 18 June 2014

Clinical characteristics and genetic analysis in women with premature ovarian insufficiency.

scientific article

Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion

scientific article

Comparative effects of dydrogesterone and medroxyprogesterone acetate in critical areas: the brain and the vessels

scientific article published on October 2007

Compensatory feto-placental upregulation of the nitric oxide system during fetal growth restriction.

scientific article

Cord plasma corticotropin-releasing factor-binding protein (CRF-BP) in term and preterm labour

scientific article published on 01 March 1997

Could transdermal estradiol + progesterone be a safer postmenopausal HRT? A review.

scientific article published on July 2008

Cranberry, D-mannose and anti-inflammatory agents prevent lower urinary tract symptoms in women undergoing prolapse surgery

scientific article published on 01 November 2019

Cytoarchitecture modifications of the human uterine endocervical mucosa in long-term three-dimensional organotypic culture

scientific article published on 26 September 2005

Dehydroepiandrosterone modulates endothelial nitric oxide synthesis via direct genomic and nongenomic mechanisms.

scientific article

Dehydroepiandrosterone, the endothelium, and cardiovascular protection

scientific article

Differential actions of estrogen and SERMs in regulation of the actin cytoskeleton of endometrial cells.

scientific article published on 18 June 2009

Differential estrogen signaling in endothelial cells upon pulsed or continuous administration.

scientific article

Differential insulin response to myo-inositol administration in obese polycystic ovary syndrome patients

scientific article published on 21 May 2012

Differential insulin response to oral glucose tolerance test (OGTT) in overweight/obese polycystic ovary syndrome patients undergoing to myo-inositol (MYO), alpha lipoic acid (ALA), or combination of both

scientific article published on 13 July 2019

Differential signal transduction of progesterone and medroxyprogesterone acetate in human endothelial cells.

scientific article published on 9 September 2004

Direct vascular effects of estrogens and selective estrogen receptor modulators

scientific article

Drospirenone and its antialdosterone properties

scientific article

Drospirenone increases endothelial nitric oxide synthesis via a combined action on progesterone and mineralocorticoid receptors

scientific article published on 02 June 2007

Dydrogesterone exerts endothelial anti-inflammatory actions decreasing expression of leukocyte adhesion molecules

scientific article published on 4 October 2011

EMAS clinical guide: assessment of the endometrium in peri and postmenopausal women.

scientific article

EMAS clinical guide: low-dose vaginal estrogens for postmenopausal vaginal atrophy

scientific article published on 20 July 2012

EMAS clinical guide: vulvar lichen sclerosus in peri and postmenopausal women

scientific article published on 03 January 2013

EMAS position statement: Diet and health in midlife and beyond

scientific article

EMAS position statement: Fertility preservation

scientific article published on 25 October 2013

EMAS position statement: Late parenthood

scientific article published on 06 August 2013

EMAS position statement: Menopause for medical students

scientific article published on 19 February 2014

EMAS position statement: Non-hormonal management of menopausal vasomotor symptoms

scientific article published on 22 April 2015

EMAS position statement: The management of postmenopausal women with vertebral osteoporotic fracture

scientific article published on 07 March 2014

EMAS position statement: The ten point guide to the integral management of menopausal health

scientific article published on 11 February 2015

EMAS position statement: individualized breast cancer screening versus population-based mammography screening programmes

scientific article published on 16 September 2014

EMAS position statement: management of uterine fibroids

scientific article published on 09 June 2014

Effects in postmenopausal women of estradiol and medroxyprogesterone alone and combined on resistance artery function and endothelial morphology and movement

scientific article published on 4 March 2008

Effects of Estetrol on Migration and Invasion in T47-D Breast Cancer Cells through the Actin Cytoskeleton

scientific article

Effects of dydrogesterone and of its stable metabolite, 20-alpha-dihydrodydrogesterone, on nitric oxide synthesis in human endothelial cells

scientific article published on 11 September 2006

Effects of metoclopramide-induced hyperprolactinemia on the prolactin and prolactin receptor expression of murine adrenal

scientific article published on 18 August 2015

Effects of phytoestrogens derived from red clover on atherogenic adhesion molecules in human endothelial cells.

scientific article

Effects of preoperative and perioperative administration of Wobenzym Vital on minimal-mild endometriosis

Effects of progesterone and medroxyprogesterone on actin remodeling and neuronal spine formation.

scientific article

Effects of raloxifene on breast cancer cell migration and invasion through the actin cytoskeleton

scientific article published on August 2009

Effects of red clover extracts on breast cancer cell migration and invasion

scientific article published on 26 May 2011

Endothelial regulation of eNOS, PAI-1 and t-PA by testosterone and dihydrotestosterone in vitro and in vivo

scientific article published on 14 June 2010

Estetrol Modulates Endothelial Nitric Oxide Synthesis in Human Endothelial Cells

scientific article published on 22 July 2015

Estetrol, a pregnancy-specific human steroid, prevents and suppresses mammary tumor growth in a rat model.

scientific article published in January 2008

Estriol administration modulates luteinizing hormone secretion in women with functional hypothalamic amenorrhea

scientific article published on 02 December 2011

Estrogen Receptor-α Promotes Breast Cancer Cell Motility and Invasion via Focal Adhesion Kinase and N-WASP ⬇️

scientific article published on September 29, 2010

Estrogen receptor alpha interacts with Galpha13 to drive actin remodeling and endothelial cell migration via the RhoA/Rho kinase/moesin pathway

scientific article published on 06 April 2006

Estrogen receptor-{alpha} promotes endothelial cell motility through focal adhesion kinase

scientific article published in December 2010

Estrogen regulates endometrial cell cytoskeletal remodeling and motility via focal adhesion kinase

scientific article published on 25 September 2010

Estrogen regulates endothelial migration via plasminogen activator inhibitor (PAI-1).

scientific article published on 2 March 2012

Estrogen-like effects of wine extracts on nitric oxide synthesis in human endothelial cells

scientific article

Estrogens and women's health: a scary or a fairy tale?

scientific article published in April 2004

Evaluation of the presence and severity of menopausal symptoms among postmenopausal women screened for the metabolic syndrome

scientific article published on 27 October 2014

Extra-nuclear signaling of estrogen receptors

scientific article published on August 2008

Extra-nuclear signaling of progesterone receptor to breast cancer cell movement and invasion through the actin cytoskeleton

scientific article

Extra-nuclear signalling of estrogen receptor to breast cancer cytoskeletal remodelling, migration and invasion

scientific article

Feto-placental nitric oxide, asymmetric dimethylarginine and vascular endothelial growth factor (VEGF) levels and VEGF gene polymorphisms in severe preeclampsia

scientific article published on 18 October 2012

Feto-placental vascular dysfunction as a prenatal determinant of adult cardiovascular disease ⬇️

scientific article published on April 1, 2013

Genomic and nongenomic mechanisms of nitric oxide synthesis induction in human endothelial cells by a fourth-generation selective estrogen receptor modulator

scientific article published in June 2002

Hard stuff for the bones

scientific article published on 01 September 2012

Hormonal contraceptive choice for women with PCOS: a systematic review of randomized trials and observational studies

scientific article published on 25 September 2014

Hormone replacement therapy in climacteric and aging brain

scientific article published on October 2003

Human placenta and fetal membranes express human urocortin mRNA and peptide.

scientific article published in October 1996

ISGE statement on oral emergency contraception

scientific article published on October 2014

In vitro effects of progesterone and progestins on vascular cells.

scientific article published on November 2003

Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

scientific article

Interference of progestins with endothelial actions of estrogens: a matter of glucocorticoid action or deprivation?

scientific article published on 29 January 2009

Italian position statement on hormone replacement therapy following the National Conference on Menopause and Hormone Replacement Therapy, Villa Tuscolana, Frascati (Rome), May 8-9, 2007.

scientific article published on January 2007

Mechanisms of action of estrogen receptors in vascular cells: relevance for menopause and aging.

scientific article published on January 2009

Medium-term outcomes after robotic-assisted lateral suspension with mesh for advanced multi-compartmental prolapse

scientific article published on 06 August 2019

Menopause and aging, quality of life and sexuality.

scientific article published on April 2007

Modulatory role of D-chiro-inositol (DCI) on LH and insulin secretion in obese PCOS patients

scientific article (publication date: June 2014)

Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells

scientific article published on February 2003

Myo-inositol modulates insulin and luteinizing hormone secretion in normal weight patients with polycystic ovary syndrome

scientific article published on 9 March 2014

Nitric oxide and pro-inflammatory cytokine serum levels in postmenopausal women with the metabolic syndrome

scientific article published on 03 April 2012

Non-genomic actions of sex steroid hormones.

scientific article

Non-genomic sex steroid actions in the vascular system.

scientific article published on May 2007

Non-hormonal management of menopausal vasomotor symptoms: Psychosocial interventions

scientific article published on 5 September 2015

Nongenomic mechanisms of endothelial nitric oxide synthase activation by the selective estrogen receptor modulator raloxifene

scientific article published in March 2002

Novel non-transcriptional mechanisms for estrogen receptor signaling in the cardiovascular system

scholarly article by Tommaso Simoncini et al published November 2002 in Steroids

Oestrogen and progestins differently prevent glutamate toxicity in cortical neurons depending on prior hormonal exposure via the induction of neural nitric oxide synthase.

scientific article

Oral dehydroepiandrosterone restores ß-endorphin response to OGTT in early and late postmenopause

scientific article published on 02 April 2019

Oregano: a source for peroxisome proliferator-activated receptor gamma antagonists

scientific article published on December 2008

Ospemifene for the treatment of vulvar and vaginal atrophy: A meta-analysis of randomized trials. Part I: Evaluation of efficacy

scientific article published on 24 November 2018

Ospemifene for the treatment of vulvar and vaginal atrophy: A meta-analysis of randomized trials. Part II: Evaluation of tolerability and safety

scientific article published on 28 November 2018

Ovarian conservation at the time of hysterectomy for benign disease: where is the pendulum now?

scientific article published in December 2014

Over hypothyroidism in a woman undergoing controlled ovarian hyperstimulation

scientific article published in January 2014

Overexpression and functional relevance of somatostatin receptor-1, -2, and -5 in endometrium and endometriotic lesions.

scientific article published on 25 August 2010

Paracrine regulation of human placenta: control of hormonogenesis

scientific article published in August 1998

Paradoxical resistance to diet-induced obesity in UCP1-deficient mice

Pelvic tuberculosis mimicking advanced ovarian cancer.

scientific article published in March 2010

Perimenopause, body fat, metabolism and menopausal symptoms in relation to serum markers of adiposity, inflammation and digestive metabolism

scientific article published on 10 January 2020

Personalized health care for midlife and beyond

scientific article published on 09 July 2015

Personalizing pelvic floor reconstructive surgery in aging women.

scientific article published on 22 June 2015

Pharmacotherapy: Benefits of menopausal hormone therapy--timing is key.

scientific article published on 27 November 2012

Pheochromocytoma diagnosed during pregnancy: a case report

scientific article published on 21 April 2020

Placental stress factors and human parturition.

scientific article published on September 1997

Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in nulliparous women complicated with preeclampsia

scientific article published on 10 March 2014

Pregnancy after miscarriage in primiparae and multiparae: implications for women's psychological well-being

scientific article published on 16 February 2020

Presence of a putative steroidal allosteric site on glycoprotein hormone receptors.

scientific article published on 17 September 2009

Progesterone enhances vascular endothelial cell migration via activation of focal adhesion kinase.

scientific article published on February 2012

Progesterone receptor enhances breast cancer cell motility and invasion via extranuclear activation of focal adhesion kinase

scientific article published on 21 April 2010

Progestogens regulate endothelial actin cytoskeleton and cell movement via the actin-binding protein moesin

scientific article

Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms

scientific article published on 05 February 2020

Raloxifene acutely stimulates nitric oxide release from human endothelial cells via an activation of endothelial nitric oxide synthase

scientific article published on 01 August 2000

Rapid nongenomic actions of thyroid hormone.

scholarly article

Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids

Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.

scientific article

Rapid signaling of estrogen to WAVE1 and moesin controls neuronal spine formation via the actin cytoskeleton.

scientific article

Selective estrogen receptor modulators: different actions on vascular cell adhesion molecule-1 (VCAM-1) expression in human endothelial cells

scientific article published on 01 February 1999

Sex steroids and their receptors: molecular actions on brain cells

scientific article published on March 2012

Tailored hormonal approach in women with premature ovarian insufficiency

scientific article published on 29 July 2019

The International Society of Gynecological Endocrinology and its president

scientific article published in March 2012

The female pelvic floor through midlife and aging

scientific article

The latest elaboration of the Women's Health Initiative data on hormone replacement therapy and cardiovascular disease in postmenopausal women

scientific article published on 01 April 2007

The metabolic syndrome and its components in postmenopausal women.

scientific article published in June 2013

The progesterone and estrogen modify the uterine prolactin and prolactin receptor expression of hyperprolactinemic mice

scientific article published on 09 October 2014

The role of Gα protein signaling in the membrane estrogen receptor-mediated signaling

scientific article published on 02 December 2020

The role of adipokines in the pathogenesis of gestational diabetes mellitus

scientific article published on 16 April 2019

Tibolone activates nitric oxide synthesis in human endothelial cells.

scientific article published in September 2004

Tibolone inhibits leukocyte adhesion molecule expression in human endothelial cells

scientific article published on 01 April 2000

Timing is everything

scientific article published in January 2007

Vasodilatory effects of the selective GPER agonist G-1 is maximal in arteries of postmenopausal women

scientific article

Wearable haptic interfaces for applications in gynecologic robotic surgery: a proof of concept in robotic myomectomy

scientific article published on 06 May 2019

Why sex matters: the biological mechanisms of cardiovascular disease.

scientific article published on 14 February 2012

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