List of works - Encarnación Martínez-Salas

3D gene of foot-and-mouth disease virus. Conservation by convergence of average sequences

scientific article

A Combined ELONA-(RT)qPCR Approach for Characterizing DNA and RNA Aptamers Selected against PCBP-2

scientific article published on 28 March 2019

A novel role for Gemin5 in mRNA translation

scientific article

Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs

scientific article published on 16 February 2012

Autosomal Recessive Cerebellar Atrophy and Spastic Ataxia in Patients With Pathogenic Biallelic Variants in <i>GEMIN5</i>

scientific article published on 28 February 2022

Bent DNA in the Large Intergenic Region of Wheat Dwarf Geminivirus

scientific article published on 01 April 1995

Cap-independent translation of maize Hsp101

scientific article published on 01 March 2005

Characterization of a cyanobacterial RNase P ribozyme recognition motif in the IRES of foot-and-mouth disease virus reveals a unique structural element

scientific article

Characterizing the function and structural organization of the 5' tRNA-like motif within the hepatitis C virus quasispecies

scientific article

Deconstructing internal ribosome entry site elements: an update of structural motifs and functional divergences

Designing synthetic RNAs to determine the relevance of structural motifs in picornavirus IRES elements

scientific article published on 7 April 2016

Developmental regulation of a proinsulin messenger RNA generated by intron retention.

scientific article

Differential factor requirement to assemble translation initiation complexes at the alternative start codons of foot-and-mouth disease virus RNA.

scientific article published on 25 June 2007

Effect of Expression of the Aphthovirus Protease 3C on Viral Infection and Gene Expression ⬇️

scientific article published on September 10, 1995

Emerging Roles of Gemin5: From snRNPs Assembly to Translation Control

scientific article published on 29 May 2020

Enhanced IRES activity by the 3'UTR element determines the virulence of FMDV isolates

scientific article published on 9 November 2013

Evidence of reciprocal tertiary interactions between conserved motifs involved in organizing RNA structure essential for internal initiation of translation

scientific article published on 22 December 2005

Evolutionary conserved motifs constrain the RNA structure organization of picornavirus IRES.

scientific article published on 15 March 2013

Exploring IRES region accessibility by interference of foot-and-mouth disease virus infectivity

scientific article

Fingerprinting the junctions of RNA structure by an open-paddlewheel diruthenium compound.

scientific article published on 12 January 2016

Foot-and-mouth disease virus infection induces proteolytic cleavage of PTB, eIF3a,b, and PABP RNA-binding proteins

scientific article published on 18 April 2007

Functional and structural analysis of maize hsp101 IRES.

scientific article

Functional and structural deficiencies of Gemin5 variants associated with neurological disorders

scientific article published on 07 April 2022

Gemin5 promotes IRES interaction and translation control through its C-terminal region

scientific article published on 5 December 2012

Gemin5 proteolysis reveals a novel motif to identify L protease targets

scientific article

Heterotypic inhibition of foot-and-mouth disease virus infection by combinations of RNA transcripts corresponding to the 5' and 3' regions

scientific article

IRES elements: features of the RNA structure contributing to their activity

scientific article published on 01 August 2002

IRES interaction with translation initiation factors: functional characterization of novel RNA contacts with eIF3, eIF4B, and eIF4GII.

scientific article

Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation

scientific article

In vivo footprint of a picornavirus internal ribosome entry site reveals differences in accessibility to specific RNA structural elements

scientific article published on November 2007

Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus

scientific article published on 13 August 2014

Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus

scientific article published on 29 June 2018

Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo

scientific article

Internal initiation of translation efficiency in different hepatitis C genotypes isolated from interferon treated patients

scientific article published on January 1999

Internal ribosome entry site biology and its use in expression vectors.

scientific article

Internal translation initiation on the foot-and-mouth disease virus IRES is affected by ribosomal stalk conformation.

scientific article

Involvement of the aphthovirus RNA region located between the two functional AUGs in start codon selection

scientific article published on March 1999

Local RNA flexibility perturbation of the IRES element induced by a novel ligand inhibits viral RNA translation

scientific article

Long-range RNA interactions between structural domains of the aphthovirus internal ribosome entry site (IRES).

scientific article published on October 1999

MDA5 cleavage by the Leader protease of foot-and-mouth disease virus reveals its pleiotropic effect against the host antiviral response

scientific article published on 02 September 2020

Magnesium-dependent folding of a picornavirus IRES element modulates RNA conformation and eIF4G interaction

scientific article

Modeling Three-Dimensional Structural Motifs of Viral IRES.

scientific article

Molecular evolution of aphthoviruses

scientific article published on January 1995

New ways of initiating translation in eukaryotes.

scientific article published on December 2001

Parameters influencing translational efficiency in aphthovirus IRES-based bicistronic expression vectors

scientific article published on September 1998

Picornavirus IRES elements: RNA structure and host protein interactions.

scientific article

Preface: functionally critical RNA structures found in positive-sense RNA viruses

scientific article

Primer design for specific diagnosis by PCR of highly variable RNA viruses: typing of foot-and-mouth disease virus

scientific article published in July 1992

RNA Structural Elements of Hepatitis C Virus Controlling Viral RNA Translation and the Implications for Viral Pathogenesis ⬇️

scientific article published on October 19, 2012

RNA-binding proteins impacting on internal initiation of translation

scientific article

RNA-protein coevolution study of Gemin5 uncovers the role of the PXSS motif of RBS1 domain for RNA binding

scientific article published on 31 May 2020

RNA-protein interaction methods to study viral IRES elements.

scientific article published on 02 July 2015

RNAiFold2T: Constraint Programming design of thermo-IRES switches

scientific article

Rab1b and ARF5 are novel RNA-binding proteins involved in FMDV IRES-driven RNA localization

Relevance of RNA structure for the activity of picornavirus IRES elements

scientific article

Rescue of internal initiation of translation by RNA complementation provides evidence for a distribution of functions between individual IRES domains

scientific article published on 21 April 2009

Response to retreatment with interferon-alpha plus ribavirin in chronic hepatitis C patients is independent of the NS5A gene nucleotide sequence

scientific article published in September 1999

Riboproteomic analysis of polypeptides interacting with the internal ribosome-entry site element of foot-and-mouth disease viral RNA.

scientific article

Ribosome-dependent conformational flexibility changes and RNA dynamics of IRES domains revealed by differential SHAPE.

scientific article

Sequence of the viral replicase gene from foot-and-mouth disease virus C1-Santa Pau (C-S8).

scientific article

Specific interference between two unrelated internal ribosome entry site elements impairs translation efficiency

scientific article published on 28 November 2005

Stable expression of antisense RNAs targeted to the 5' non-coding region confers heterotypic inhibition to foot-and-mouth disease virus infection

scientific article published on February 2003

Structural analysis provides insights into the modular organization of picornavirus IRES.

scientific article published on 5 November 2010

Structural basis for the biological relevance of the invariant apical stem in IRES-mediated translation.

scientific article published on 8 July 2011

Structural basis for the dimerization of Gemin5 and its role in protein recruitment and translation control

scientific article published on 01 January 2020

Structural insights into viral IRES-dependent translation mechanisms

scientific article published on 21 May 2015

Structural organization of a viral IRES depends on the integrity of the GNRA motif.

scientific article

Susceptibility to viral infection is enhanced by stable expression of 3A or 3AB proteins from foot-and-mouth disease virus

scientific article

Tailoring the switch from IRES-dependent to 5'-end-dependent translation with the RNase P ribozyme

scientific article

The 3' end of the foot-and-mouth disease virus genome establishes two distinct long-range RNA-RNA interactions with the 5' end region

scientific article published in October 2006

The impact of RNA structure on picornavirus IRES activity.

scientific article published on 15 April 2008

The landscape of the non-canonical RNA-binding site of Gemin5 unveils a feedback loop counteracting the negative effect on translation.

scientific article

The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance--a review

scientific article

Upstream AUGs in embryonic proinsulin mRNA control its low translation level.

scientific article published on October 2003

Using RNA inverse folding to identify IRES-like structural subdomains.

scientific article

List of works by Encarnación Martínez-Salas

3D gene of foot-and-mouth disease virus. Conservation by convergence of average sequences

A Combined ELONA-(RT)qPCR Approach for Characterizing DNA and RNA Aptamers Selected against PCBP-2

A novel role for Gemin5 in mRNA translation

Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs

Autosomal Recessive Cerebellar Atrophy and Spastic Ataxia in Patients With Pathogenic Biallelic Variants in <i>GEMIN5</i>

Bent DNA in the Large Intergenic Region of Wheat Dwarf Geminivirus

Cap-independent translation of maize Hsp101

Characterization of a cyanobacterial RNase P ribozyme recognition motif in the IRES of foot-and-mouth disease virus reveals a unique structural element

Characterizing the function and structural organization of the 5' tRNA-like motif within the hepatitis C virus quasispecies

Deconstructing internal ribosome entry site elements: an update of structural motifs and functional divergences

Designing synthetic RNAs to determine the relevance of structural motifs in picornavirus IRES elements

Developmental regulation of a proinsulin messenger RNA generated by intron retention.

Differential factor requirement to assemble translation initiation complexes at the alternative start codons of foot-and-mouth disease virus RNA.

Effect of Expression of the Aphthovirus Protease 3C on Viral Infection and Gene Expression ⬇️

Emerging Roles of Gemin5: From snRNPs Assembly to Translation Control

Enhanced IRES activity by the 3'UTR element determines the virulence of FMDV isolates

Evidence of reciprocal tertiary interactions between conserved motifs involved in organizing RNA structure essential for internal initiation of translation

Evolutionary conserved motifs constrain the RNA structure organization of picornavirus IRES.

Exploring IRES region accessibility by interference of foot-and-mouth disease virus infectivity

Fingerprinting the junctions of RNA structure by an open-paddlewheel diruthenium compound.

Foot-and-mouth disease virus infection induces proteolytic cleavage of PTB, eIF3a,b, and PABP RNA-binding proteins

Functional and structural analysis of maize hsp101 IRES.

Functional and structural deficiencies of Gemin5 variants associated with neurological disorders

Gemin5 promotes IRES interaction and translation control through its C-terminal region

Gemin5 proteolysis reveals a novel motif to identify L protease targets

Heterotypic inhibition of foot-and-mouth disease virus infection by combinations of RNA transcripts corresponding to the 5' and 3' regions

IRES elements: features of the RNA structure contributing to their activity

IRES interaction with translation initiation factors: functional characterization of novel RNA contacts with eIF3, eIF4B, and eIF4GII.

Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation

In vivo footprint of a picornavirus internal ribosome entry site reveals differences in accessibility to specific RNA structural elements

Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus

Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus

Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo

Internal initiation of translation efficiency in different hepatitis C genotypes isolated from interferon treated patients

Internal ribosome entry site biology and its use in expression vectors.

Internal translation initiation on the foot-and-mouth disease virus IRES is affected by ribosomal stalk conformation.

Involvement of the aphthovirus RNA region located between the two functional AUGs in start codon selection

Local RNA flexibility perturbation of the IRES element induced by a novel ligand inhibits viral RNA translation

Long-range RNA interactions between structural domains of the aphthovirus internal ribosome entry site (IRES).

MDA5 cleavage by the Leader protease of foot-and-mouth disease virus reveals its pleiotropic effect against the host antiviral response

Magnesium-dependent folding of a picornavirus IRES element modulates RNA conformation and eIF4G interaction

Modeling Three-Dimensional Structural Motifs of Viral IRES.

Molecular evolution of aphthoviruses

New ways of initiating translation in eukaryotes.

Parameters influencing translational efficiency in aphthovirus IRES-based bicistronic expression vectors

Picornavirus IRES elements: RNA structure and host protein interactions.

Preface: functionally critical RNA structures found in positive-sense RNA viruses

Primer design for specific diagnosis by PCR of highly variable RNA viruses: typing of foot-and-mouth disease virus

RNA Structural Elements of Hepatitis C Virus Controlling Viral RNA Translation and the Implications for Viral Pathogenesis ⬇️

RNA-binding proteins impacting on internal initiation of translation

RNA-protein coevolution study of Gemin5 uncovers the role of the PXSS motif of RBS1 domain for RNA binding

RNA-protein interaction methods to study viral IRES elements.

RNAiFold2T: Constraint Programming design of thermo-IRES switches

Rab1b and ARF5 are novel RNA-binding proteins involved in FMDV IRES-driven RNA localization

Relevance of RNA structure for the activity of picornavirus IRES elements

Rescue of internal initiation of translation by RNA complementation provides evidence for a distribution of functions between individual IRES domains

Response to retreatment with interferon-alpha plus ribavirin in chronic hepatitis C patients is independent of the NS5A gene nucleotide sequence

Riboproteomic analysis of polypeptides interacting with the internal ribosome-entry site element of foot-and-mouth disease viral RNA.

Ribosome-dependent conformational flexibility changes and RNA dynamics of IRES domains revealed by differential SHAPE.

Sequence of the viral replicase gene from foot-and-mouth disease virus C1-Santa Pau (C-S8).

Specific interference between two unrelated internal ribosome entry site elements impairs translation efficiency

Stable expression of antisense RNAs targeted to the 5' non-coding region confers heterotypic inhibition to foot-and-mouth disease virus infection

Structural analysis provides insights into the modular organization of picornavirus IRES.

Structural basis for the biological relevance of the invariant apical stem in IRES-mediated translation.

Structural basis for the dimerization of Gemin5 and its role in protein recruitment and translation control

Structural insights into viral IRES-dependent translation mechanisms

Structural organization of a viral IRES depends on the integrity of the GNRA motif.

Susceptibility to viral infection is enhanced by stable expression of 3A or 3AB proteins from foot-and-mouth disease virus

Tailoring the switch from IRES-dependent to 5'-end-dependent translation with the RNase P ribozyme

The 3' end of the foot-and-mouth disease virus genome establishes two distinct long-range RNA-RNA interactions with the 5' end region

The impact of RNA structure on picornavirus IRES activity.

The landscape of the non-canonical RNA-binding site of Gemin5 unveils a feedback loop counteracting the negative effect on translation.

The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance--a review

Upstream AUGs in embryonic proinsulin mRNA control its low translation level.

Using RNA inverse folding to identify IRES-like structural subdomains.