Search filters

List of works by Mohammad Hojjat-Farsangi

A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib.

scientific article

Adenosine and adenosine receptors in the immunopathogenesis and treatment of cancer.

scientific article published on 24 February 2017

Altered T-cell subpopulations in recurrent pregnancy loss patients with cellular immune abnormalities

scientific article published on 06 September 2018

An immunotherapeutic method for COVID-19 patients: a soluble ACE2-Anti-CD16 VHH to block SARS-CoV-2 Spike protein

scientific article published on 14 July 2020

Anti-angiogenic effects of CD73-specific siRNA-loaded nanoparticles in breast cancer-bearing mice

scientific article published on 09 May 2018

Application of nanomedicine for crossing the blood-brain barrier: Theranostic opportunities in multiple sclerosis.

scientific article

Assessment of the immune system in 55 Iranian patients with vitiligo

scientific article published on 01 November 2005

Association of Tumor Growth Factor-β and Interferon-γ Serum Levels With Insulin Resistance in Normal Pregnancy

scientific article published on 28 September 2015

Autologous T cells expressing the oncogenic transcription factor KLF6-SV1 prevent apoptosis of chronic lymphocytic leukemia cells

scientific article published on 12 February 2018

Blockage of immune checkpoint molecules increases T-cell priming potential of dendritic cell vaccine

scientific article published on 24 October 2019

CD73 as a potential opportunity for cancer immunotherapy

scientific article published on 26 December 2018

CDK1 in Breast Cancer: Implications for Theranostic Potential

scientific article published on 03 February 2020

Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis

scientific article

Concomitant blockade of A2AR and CTLA-4 by siRNA-loaded polyethylene glycol-chitosan-alginate nanoparticles synergistically enhances antitumor T-cell responses

scientific article published on 02 June 2020

Construction and characterization of a new chimeric antibody against HER2.

scientific article published in July 2013

Construction of a hepatitis B virus neutralizing chimeric monoclonal antibody recognizing escape mutants of the viral surface antigen (HBsAg).

scientific article published on 19 June 2017

Differential regulation of B-cell proliferation by IL21 in different subsets of chronic lymphocytic leukemia.

scientific article published on 9 April 2013

Dimethyl fumarate: Regulatory effects on the immune system in the treatment of multiple sclerosis

scientific article published on 07 December 2018

Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia

scientific article published on 16 April 2016

Downregulation of A2AR by siRNA loaded PEG-chitosan-lactate nanoparticles restores the T cell mediated anti-tumor responses through blockage of PKA/CREB signaling pathway

scientific article published on 30 March 2019

E2 ubiquitin-conjugating enzymes in cancer: Implications for immunotherapeutic interventions

scientific article published on 21 August 2019

Expression profile of galectin-1 and galectin-3 molecules in different subtypes of chronic lymphocytic leukemia.

scientific article

Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia

scientific article published on 01 November 2008

First-in-class oral small molecule inhibitor of the tyrosine kinase ROR1 (KAN0439834) induced significant apoptosis of chronic lymphocytic leukemia cells.

scientific article

Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy.

scientific article published on 05 July 2015

Frequency analysis of HLA class I alleles in Iranian patients with progressive and non-progressive chronic lymphocytic leukemia

scientific article published on 21 November 2013

Human leukocyte antigen class II allele association to disease progression in Iranian patients with chronic lymphocytic leukemia.

scientific article

Ibrutinib-A double-edge sword in cancer and autoimmune disorders.

scientific article published on 11 September 2015

Immunoglobulin heavy chain variable region gene usage and mutational status of the leukemic B cells in Iranian patients with chronic lymphocytic leukemia

scientific article published on 02 September 2009

Immunophenotypic characterization of the leukemic B-cells from Iranian patients with chronic lymphocytic leukemia: association between CD38 expression and disease progression.

scientific article published in March 2008

Increased frequency of CD8+ and CD4+ regulatory T cells in chronic lymphocytic leukemia: association with disease progression

scientific article published on 03 January 2013

Induction of IgM, IgA and IgE antibodies in colorectal cancer patients vaccinated with a recombinant CEA protein

scientific article published on 02 March 2012

Lack of Association Between rs17568 Polymorphism in OX40 Gene and Myocardial Infarction, Southern of Iran

scientific article published on 28 September 2015

Ligation of human Fc receptor like-2 by monoclonal antibodies down-regulates B-cell receptor-mediated signalling.

scientific article published on November 2014

Mechanisms of tumor cell resistance to the current targeted-therapy agents.

scientific article published on 7 May 2016

Metabolic syndrome mediates proinflammatory responses of inflammatory cells in preeclampsia

scientific article published on 05 February 2019

Molecular Profiling of Pheochromocytoma and Abdominal Paraganglioma Stratified by the PASS Algorithm Reveals Chromogranin B as Associated With Histologic Prediction of Malignant Behavior

scientific article published on 01 March 2019

Monoclonal antibodies against ROR1 induce apoptosis of chronic lymphocytic leukemia (CLL) cells.

scientific article published on 6 January 2012

Nanoparticles and targeted drug delivery in cancer therapy

scientific article published on 28 July 2017

Novel and emerging targeted-based cancer therapy agents and methods

scientific article published on 9 February 2015

Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies

scientific article published on 9 October 2012

PD-L1/PD-1 axis as a potent therapeutic target in breast cancer

scientific article published on 16 February 2020

Polymorphism of Foxp3 Gene Affects the Frequency of Regulatory T Cells and Disease Activity in Patients with Rheumatoid Arthritis in Iranian Population

article

Promising immunotherapy: Highlighting cytokine-induced killer cells

scientific article published on 16 December 2018

Prostaglandin E2 as a potent therapeutic target for treatment of colon cancer

scientific article published on 15 May 2019

ROR1 Is Expressed in Diffuse Large B-Cell Lymphoma (DLBCL) and a Small Molecule Inhibitor of ROR1 (KAN0441571C) Induced Apoptosis of Lymphoma Cells

scientific article published on 23 June 2020

Recent advances in targeting mTOR signaling pathway using small molecule inhibitors

scientific article published on 15 September 2016

S1PR1 as a Novel Promising Therapeutic Target in Cancer Therapy

scientific article published on 01 August 2019

Sero-Epidemiological Study of Hepatitis E Virus among Thalassemia as High Risk Patients: A Cross-Sectional Survey in Jahrom, Southern, Iran

scientific article published on 02 February 2016

Silencing of IL-6 and STAT3 by siRNA loaded hyaluronate-N,N,N-trimethyl chitosan nanoparticles potently reduces cancer cell progression

scientific article published on 28 January 2020

Smac mimetics as novel promising modulators of apoptosis in the treatment of breast cancer

scientific article published on 03 December 2018

Small-molecule inhibitors of the receptor tyrosine kinases: promising tools for targeted cancer therapies

scientific article

Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia

scientific article published on 12 November 2015

T cells from indolent CLL patients prevent apoptosis of leukemic B cells in vitro and have altered gene expression profile.

scientific article

Targeting Receptor Tyrosine Kinases Using Monoclonal Antibodies: The Most Specific Tools for Targeted-Based Cancer Therapy

scientific article published on 30 September 2015

Targeting non-receptor tyrosine kinases using small molecule inhibitors: an overview of recent advances

scientific article published on 27 July 2015

Telomere length and expression of human telomerase reverse transcriptase splice variants in chronic lymphocytic leukemia

scientific article

The PI3K/AKT/mTOR pathway is involved in direct apoptosis of CLL cells induced by ROR1 monoclonal antibodies.

scientific article published on 19 November 2014

The imbalance of Th17/Treg axis involved in the pathogenesis of preeclampsia

scientific article published on 02 October 2018

The receptor tyrosine kinase ROR1--an oncofetal antigen for targeted cancer therapy

scientific article

The role of DEAD-box RNA helicase p68 (DDX5) in the development and treatment of breast cancer

scientific article published on 11 November 2018

The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer

scientific article published on 06 October 2018

The skewed balance between Tregs and Th17 in chronic lymphocytic leukemia.

scientific article published on January 2015

The tyrosine kinase receptor ROR1 is constitutively phosphorylated in chronic lymphocytic leukemia (CLL) cells.

scientific article

Variation in WNT genes expression in different subtypes of chronic lymphocytic leukemia

scientific article

Whole Tumor Cell Vaccine Adjuvants: Comparing IL-12 to IL-2 and IL-15.

scientific article published on September 2016

Paulina is supported by:

About Paulina

Help