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List of works by Edecio Cunha-Neto

A DNA vaccine encoding multiple HIV CD4 epitopes elicits vigorous polyfunctional, long-lived CD4+ and CD8+ T cell responses

scientific article (publication date: 11 February 2011)

A Recombinant Adenovirus Encoding Multiple HIV-1 Epitopes Induces Stronger CD4(+) T cell Responses than a DNA Vaccine in Mice

scientific article published on December 2011

A vaccine encoding conserved promiscuous HIV CD4 epitopes induces broad T cell responses in mice transgenic to multiple common HLA class II molecules

scientific article (publication date: 11 June 2010)

An Approach for a Synthetic CTL Vaccine Design against Zika Flavivirus Using Class I and Class II Epitopes Identified by Computer Modeling

scientific article

Autoimmunity

article

Autoimmunity in Chagas' Disease

Autoimmunity in chagas disease cardiomyopathy: Fulfilling the criteria at last?

scientific article published in October 1996

Bicistronic DNA vaccines simultaneously encoding HIV, HSV and HPV antigens promote CD8⁺ T cell responses and protective immunity

scientific article

Blood Gene Signatures of Chagas Cardiomyopathy With or Without Ventricular Dysfunction

scientific article published on 21 December 2016

Broad and cross-clade CD4+ T-cell responses elicited by a DNA vaccine encoding highly conserved and promiscuous HIV-1 M-group consensus peptides

scientific article

Bupivacaine enhances the magnitude and longevity of HIV-specific immune response after immunization with a CD4 epitope-based DNA vaccine

article

CD4+ T cell epitope discovery and rational vaccine design

scientific article published on 14 February 2010

CD4+ T cells from HIV-1-infected patients recognize wild-type and mutant human immunodeficiency virus-1 protease epitopes

scientific article published on 24 February 2011

CXCL9/Mig mediates T cells recruitment to valvular tissue lesions of chronic rheumatic heart disease patients

scientific article published on August 2013

Can an immune-regulatory vaccine prevent HIV infection?

scientific article published in March 2012

Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis

scientific article published on 17 April 2018

Chagas disease cardiomyopathy: current concepts of an old disease

scientific article published on March 2008

Chagas disease cardiomyopathy: immunopathology and genetics

scientific article

Changes in neuropsychological tests and brain metabolism after bariatric surgery

scientific article

Characterization of cDNA clones encoding ribonucleoprotein antigens expressed in Trypanosoma cruzi amastigotes

scientific article

Chronic Chagas Heart Disease Management: From Etiology to Cardiomyopathy Treatment

scientific article published on September 2017

Chronic Chagas' disease cardiomyopathy patients display an increased IFN-gamma response to Trypanosoma cruzi infection.

scientific article

Circulating miR-1 as a potential biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients

scientific article published on 29 December 2016

Circulating plasma microRNAs dysregulation and metabolic endotoxemia induced by a high-fat high-saturated diet

scientific article published on 07 March 2019

Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy

scientific article published on 11 November 2021

Co-administration of plasmid-encoded granulocyte-macrophage colony-stimulating factor increases human immunodeficiency virus-1 DNA vaccine-induced polyfunctional CD4+ T-cell responses.

scientific article

Cognitive Effects of Intentional Weight Loss in Elderly Obese Individuals With Mild Cognitive Impairment

scientific article

Corrigendum to: Blood Gene Signatures of Chagas Cardiomyopathy With or Without Ventricular Dysfunction

scientific article published on 01 April 2020

Dendritic Cell Targeting Effectively Boosts T Cell Responses Elicited by an HIV Multiepitope DNA Vaccine

scientific article published on 07 February 2017

Differential microRNA Profile in Operational Tolerance: A Potential Role in Favoring Cell Survival

Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells

scientific article published on 2 February 2018

Distinct mitral valve proteomic profiles in rheumatic heart disease and myxomatous degeneration

scientific article

Distinct outcomes of Trypanosoma cruzi infection in hamsters are related to myocardial parasitism, cytokine/chemokine gene expression, and protein expression profile

scientific article published in August 2008

Ebi3 Prevents Trypanosoma cruzi-Induced Myocarditis by Dampening IFN-γ-Driven Inflammation

scientific article published on 26 September 2017

Epitope mapping of a single repetitive unit of the B13 Trypanosoma cruzi antigen as fusions to Escherichia coli LamB protein

scientific article published in June 2004

Evidence for T Cell Help in the IgG Response against Tandemly Repetitive Trypanosoma cruzi B13 Protein in Chronic Chagas Disease Patients

scientific article published on 19 February 2012

Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?

scientific article published on 15 March 2018

Experimental chronic Chagas' disease myocarditis is an autoimmune disease preventable by induction of immunological tolerance to myocardial antigens

scientific article published in March 2002

Functional IL18 polymorphism and susceptibility to Chronic Chagas Disease

scientific article published on 2 March 2015

Gene expression profile in long-term non progressor HIV infected patients: in search of potential resistance factors.

scientific article published on 24 June 2014

Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways.

scientific article

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects

scientific article

HIV Envelope Trimer Specific Immune Response Is Influenced by Different Adjuvant Formulations and Heterologous Prime-Boost

scientific article published on 4 January 2016

HLA and β-myosin heavy chain do not influence susceptibility to Chagas' disease cardiomyopathy

Heart-directed autoimmunity: the case of rheumatic fever

scientific article published on May 2001

Heterozygosity for the S180L variant of MAL/TIRAP, a gene expressing an adaptor protein in the Toll-like receptor pathway, is associated with lower risk of developing chronic Chagas cardiomyopathy

scientific article

Histopathological Correlates of Global and Segmental Left Ventricular Systolic Dysfunction in Experimental Chronic Chagas Cardiomyopathy

scientific article published on 21 January 2016

Human T cell epitope mapping of the Schistosoma mansoni 14-kDa fatty acid-binding protein using cells from patients living in areas endemic for schistosomiasis

scientific article

Identification of multiple HLA-A*0201-restricted cruzipain and FL-160 CD8+ epitopes recognized by T cells from chronically Trypanosoma cruzi-infected patients

scientific article

Identification of novel consensus CD4 T-cell epitopes from clade B HIV-1 whole genome that are frequently recognized by HIV-1 infected patients

scientific article published in November 2006

Identification of paramyosin T cell epitopes associated with human resistance to Schistosoma mansoni reinfection.

scientific article published in December 2005

Immunogenicity of a recombinant protein containing the Plasmodium vivax vaccine candidate MSP1(19) and two human CD4+ T-cell epitopes administered to non-human primates (Callithrix jacchus jacchus).

scientific article published on 2 June 2006

Immunology and infection by protozoan parasites

scientific article

Increased gene expression of inflammatory markers in nasal turbinate of patients with persistent allergic rhinitis and chronic obstruction

scientific article published on 30 July 2019

Induction of IL-12 production in human peripheral monocytes by Trypanosoma cruzi Is mediated by glycosylphosphatidylinositol-anchored mucin-like glycoproteins and potentiated by IFN- γ and CD40-CD40L interactions

scientific article

Induction of cardiac autoimmunity in Chagas heart disease: a case for molecular mimicry

scientific article

Inflammatory and cardiac biomarkers are differentially expressed in clinical stages of Chagas disease

scientific article published on 12 July 2015

Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection

scientific article published on 21 December 2017

Interferon-γ and other inflammatory mediators in cardiomyocyte signaling during Chagas disease cardiomyopathy

scientific article

Lack of association of tumor necrosis factor-alpha polymorphisms with Chagas disease in Brazilian patients

scientific article published on 27 November 2006

Locally produced survival cytokines IL-15 and IL-7 may be associated to the predominance of CD8+ T cells at heart lesions of human chronic Chagas disease cardiomyopathy.

scientific article

Longitudinal study of patients with chronic Chagas cardiomyopathy in Brazil (SaMi-Trop project): a cohort profile

scientific article published on 4 May 2016

MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological Outcomes

scientific article published on 18 June 2015

MicroRNAs miR-1, miR-133a, miR-133b, miR-208a and miR-208b are dysregulated in Chronic Chagas disease Cardiomyopathy

Modulating APOBEC expression enhances DNA vaccine immunogenicity

scientific article published on 8 May 2015

Multiple Approaches for Increasing the Immunogenicity of an Epitope-Based Anti-HIV Vaccine

scientific article published on 06 July 2015

Mycobacterium tuberculosis epitope-specific interferon-g production in healthy Brazilians reactive and non-reactive to tuberculin skin test.

scientific article published on 9 December 2014

Myocardial Infarction–Associated Transcript, a Long Noncoding RNA, Is Overexpressed During Dilated Cardiomyopathy Due to Chronic Chagas Disease

scientific article

Myocardial chemokine expression and intensity of myocarditis in Chagas cardiomyopathy are controlled by polymorphisms in CXCL9 and CXCL10.

scientific article

Myocardial gene and protein expression profiles after autoimmune injury in Chagas' disease cardiomyopathy

scientific article published on 29 September 2010

Myocardial gene expression of T-bet, GATA-3, Ror-γt, FoxP3, and hallmark cytokines in chronic Chagas disease cardiomyopathy: an essentially unopposed TH1-type response

scientific article

P16-39. T cell recognition of autologous and non-autologous HIV-1 protease peptides by HIV-1 infected patients undergoing PI therapy

article

P16-53. Distinct subsets of memory T lymphocytes from HIV-1-infected subjects secrete IFN-γ and IL-2 in response to novel CD4+ T-cell HIV-1 epitopes

article

P19-44. Priming with a DNA vaccine enconding HIV CD4+ T cell epitopes enhances responses against subsequent immunization with plasmid encoding Vif

article

PDIA3, HSPA5 and vimentin, proteins identified by 2-DE in the valvular tissue, are the target antigens of peripheral and heart infiltrating T cells from chronic rheumatic heart disease patients

scientific article

Pathogenesis of chronic Chagas heart disease

scientific article

Peptides containing T cell epitopes, derived from Sm14, but not from paramyosin, induce a Th1 type of immune response, reduction in liver pathology and partial protection against Schistosoma mansoni infection in mice

article

Plasma cytokine profile in tropical endomyocardial fibrosis: predominance of TNF-a, IL-4 and IL-10.

scientific article

Polymorphism in the alpha cardiac muscle actin 1 gene is associated to susceptibility to chronic inflammatory cardiomyopathy.

scientific article

Polymorphisms in the gene for lymphotoxin-alpha predispose to chronic Chagas cardiomyopathy.

scientific article

Proteins differentially expressed in human beta-cells-enriched pancreatic islet cultures and human insulinomas

scientific article published on 24 July 2013

Proteomic inventory of myocardial proteins from patients with chronic Chagas' cardiomyopathy

scientific article published in December 2006

Publisher Correction: Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells

scientific article published on 13 March 2018

Purification, sequencing and structural characterization of the phospholipase A1 from the venom of the social wasp Polybia paulista (Hymenoptera, Vespidae).

scientific article

Regulation of Leishmania (L.) amazonensis protein expression by host T cell dependent responses: differential expression of oligopeptidase B, tryparedoxin peroxidase and HSP70 isoforms in amastigotes isolated from BALB/c and BALB/c nude mice

scientific article

Retro-inverso peptide analogues of Trypanosoma cruzi B13 protein epitopes fail to be recognized by human sera and peripheral blood mononuclear cells

scientific article published on 01 June 2001

Rheumatic Heart Disease and Myxomatous Degeneration: Differences and Similarities of Valve Damage Resulting from Autoimmune Reactions and Matrix Disorganization

scientific article

Selective decrease of components of the creatine kinase system and ATP synthase complex in chronic Chagas disease cardiomyopathy

scientific article

Short communication: Trypanosoma cruzi lineage I in endomyocardial biopsy from a north-eastern Brazilian patient at end-stage chronic chagasic cardiomyopathy

article

T cell epitope characterization in tandemly repetitive Trypanosoma cruzi B13 protein

scientific article published in August 2005

T-cell molecular mimicry in Chagas disease: identification and partial structural analysis of multiple cross-reactive epitopes between Trypanosoma cruzi B13 and cardiac myosin heavy chain

scientific article

T-cell reactivity against streptococcal antigens in the periphery mirrors reactivity of heart-infiltrating T lymphocytes in rheumatic heart disease patients

scientific article published on September 2001

T-cell recognition and cytokine profile induced by melanocyte epitopes in patients with HLA-DRB1*0405-positive and -negative Vogt-Koyanagi-Harada uveitis

scientific article published on July 2005

T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals

scientific article published on 28 February 2007

TNF blockade aggravates experimental chronic Chagas disease cardiomyopathy

scientific article published on 18 May 2007

TNF gene polymorphisms are associated with reduced survival in severe Chagas' disease cardiomyopathy patients

article

The CD8⁺ memory stem T cell (T(SCM)) subset is associated with improved prognosis in chronic HIV-1 infection

scientific article

The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi

scientific article

The Syrian hamster as a model for the dilated cardiomyopathy of Chagas' disease: a quantitative echocardiographical and histopathological analysis.

scientific article published in October 2003

The effect of beta-blockade on myocardial remodelling in Chagas' cardiomyopathy.

scientific article

The hamster (Mesocricetus auratus) as an experimental model of toxocariasis: histopathological, immunohistochemical, and immunoelectron microscopic findings

scientific article published on 19 December 2014

The monocyte chemoattractant protein-1 gene polymorphism is associated with cardiomyopathy in human chagas disease

scientific article published on 16 June 2006

Trypanosoma cruzi: Conformational Preferences of Antigenic Peptides Bearing the Immunodominant Epitope of the B13 Antigen

scientific article published on 01 September 1999

Variants in the promoter region of IKBL/NFKBIL1 gene may mark susceptibility to the development of chronic Chagas' cardiomyopathy among Trypanosoma cruzi-infected individuals

scientific article

Whole genome Cardiac DNA methylation fingerprint and gene expression analysis provide new insights in the pathogenesis of Chronic Chagas disease Cardiomyopathy

scientific article published on 30 May 2017

miRNAs may play a major role in the control of gene expression in key pathobiological processes in Chagas disease cardiomyopathy

scientific article published on 22 December 2020

p16INK4a Expression and Immunologic Aging in Chronic HIV Infection

scientific article