List of works by Delia Mezzanzanica

A Cell-Autonomous Oncosuppressive Role of Human RNASET2 Affecting ECM-Mediated Oncogenic Signaling

scientific article published on 22 February 2019

A critical comparison of three internalization assays applied to the evaluation of a given mAb as a toxin-carrier candidate.

scientific article published on July 1993

A miRNA signature assessing ovarian cancer prognosis

scientific article published on 2 December 2016

A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing

scientific article published on September 2004

A step further in understanding the biology of the folate receptor in ovarian carcinoma.

scientific article

Activated leukocyte cell adhesion molecule soluble form: a potential biomarker of epithelial ovarian cancer is increased in type II tumors

scientific article published on 13 December 2012

Activation of mononuclear cells to be used for hybrid monoclonal antibody-induced lysis of human ovarian carcinoma cells

scientific article published on 01 September 1988

Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells

scientific article

Alterations of choline phospholipid metabolism in ovarian tumor progression

scientific article published on October 2005

Analysis of production, purification, and cytolytic potential of bi-specific antibodies reactive with ovarian-carcinoma-associated antigens and the T-cell antigen CD3

article

Anti-CD3/anti-epidermal growth factor receptor-bispecific antibody retargeting of lymphocytes against human neoplastic keratinocytes in an autologous organotypic culture model

scientific article published on January 2002

Anti-ovarian carcinoma anti-T3 heteroconjugates or hybrid antibodies induce tumor cell lysis by cytotoxic T-cells.

scientific article published in January 1988

Approaches to implement bispecific antibody treatment of ovarian carcinoma

scientific article published on 01 November 1997

Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers

scientific article

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC.

scientific article published on 15 September 2016

Bispecific antibodies and retargeted cellular cytotoxicity: novel approaches to cancer therapy

scientific article published on 01 January 1992

Bispecific antibody targeted T cell therapy of ovarian cancer: clinical results and future directions

scientific article published on October 1995

CD3-CD28 costimulation as a means to avoiding T cell preactivation in bispecific monoclonal antibody-based treatment of ovarian carcinoma

scientific article published on 01 December 1996

CD95-mediated apoptosis is impaired at receptor level by cellular FLICE-inhibitory protein (long form) in wild-type p53 human ovarian carcinoma

scientific article published on August 2004

Cellular FLICE-inhibitory protein (c-FLIP) signalling: a key regulator of receptor-mediated apoptosis in physiologic context and in cancer

scientific article

Change in binding reactivity of an anti-tumor monoclonal antibody after the introduction of 2-pyridyl disulphide groups.

scientific article published in January 1986

Characterisation of in vivo ovarian cancer models by quantitative 1H magnetic resonance spectroscopy and diffusion-weighted imaging

scientific article

Characterization of human ovarian carcinoma-associated antigens defined by novel monoclonal antibodies with tumor-restricted specificity.

scientific article published in March 1987

Chimeric murine-human antibodies directed against folate binding receptor are efficient mediators of ovarian carcinoma cell killing

scientific article published on May 1994

Choline Metabolism Alteration: A Focus on Ovarian Cancer

scientific article

Choline kinase alpha impairment overcomes TRAIL resistance in ovarian cancer cells

scientific article published on 04 January 2021

Choline kinase-alpha by regulating cell aggressiveness and drug sensitivity is a potential druggable target for ovarian cancer.

scientific article

Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma

scientific article published on 19 August 2013

Complement activated by chimeric anti-folate receptor antibodies is an efficient effector system to control ovarian carcinoma

scientific article published on April 2006

Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells

scientific article published on 06 August 2018

Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study.

scientific article published on 8 July 2016

Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism.

scientific article

Effect of radiochemical modification on biodistribution of scFvD2B antibody fragment recognising prostate specific membrane antigen

scientific article published on 21 September 2015

Efficiency of T cell triggering by anti-CD3 monoclonal antibodies (mAb) with potential usefulness in bispecific mAb generation

scientific article published on 01 July 1997

Epigenetic control of autophagy by microRNAs in ovarian cancer

scientific article

Expression of interleukin-18 in human ovarian carcinoma and normal ovarian epithelium: evidence for defective processing in tumor cells

scientific article

Focal Recurrent Copy Number Alterations Characterize Disease Relapse in High Grade Serous Ovarian Cancer Patients with Good Clinical Prognosis: A Pilot Study

scientific article published on 05 September 2019

Full preclinical validation of the 123I-labeled anti-PSMA antibody fragment ScFvD2B for prostate cancer imaging

scientific article published on 30 December 2016

Gene expression profiling of advanced ovarian cancer: characterization of a molecular signature involving fibroblast growth factor 2.

scientific article published on October 2004

Genomic Landscape of Ovarian Cancer

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma

scientific article published on May 2015

Guidance of Signaling Activations by Cadherins and Integrins in Epithelial Ovarian Cancer Cells

scientific article

Gynecologic Cancer InterGroup (GCIG) consensus review for clear cell carcinoma of the ovary

scientific article

Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian sex cord stromal tumors

scientific article

Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian tumors of low malignant potential (borderline ovarian tumors).

scientific article

Gynecological Cancers Translational, Research Implementation, and Harmonization: Gynecologic Cancer InterGroup Consensus and Still Open Questions

scientific article published on 26 February 2019

High-throughput assessment of the antibody profile in ovarian cancer ascitic fluids

scientific article published on 04 June 2019

Highly efficient redirected anti-tumor activity of human lymphocytes transduced with a completely human chimeric immune receptor

scientific article

Human T-lymphocytes targeted against an established human ovarian carcinoma with a bispecific F(ab')2 antibody prolong host survival in a murine xenograft model

scientific article published in October 1991

Human carcinoma cell lines xenografted in athymic mice: biological and antigenic characteristics of an intraabdominal model

article

Human ovarian carcinoma lysis by cytotoxic t cells targeted by bispecific monoclonal antibodies: Analysis of the antibody components

article

Human peripheral blood lymphocytes targeted with bispecific antibodies release cytokines that are essential for inhibiting tumor growth

scientific article published in May 1991

IL-27 induces the expression of IDO and PD-L1 in human cancer cells

scientific article published on 9 December 2015

Identification of a chrXq27.3 microRNA cluster associated with early relapse in advanced stage ovarian cancer patients

scientific article published on April 2015

Immunoconjugate generation between the ribosome inactivating protein restrictocin and an anti-human breast carcinoma MAB

scientific article published on 01 January 1988

Impact of COVID-19 in gynecologic oncology: a Nationwide Italian Survey of the SIGO and MITO groups

scientific article published on 01 November 2020

In vivo Magnetic Resonance Metabolic and Morphofunctional Fingerprints in Experimental Models of Human Ovarian Cancer

scientific article

Increased sensitivity to chemotherapy induced by CpG-ODN treatment is mediated by microRNA modulation

scientific article

Integration of MRI and MRS approaches to monitor molecular imaging and metabolomic effects of trabectedin on a preclinical ovarian cancer model

scientific article published on 30 October 2018

Interleukin (IL)-18, a biomarker of human ovarian carcinoma, is predominantly released as biologically inactive precursor

scientific article published on 6 January 2011

Key nodes of a microRNA network associated with the integrated mesenchymal subtype of high-grade serous ovarian cancer ⬇️

scientific article

M-CAM expression as marker of poor prognosis in epithelial ovarian cancer

scientific article published on October 2006

MiR-506 inhibits multiple targets in the epithelial-to-mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer

scientific article

MiR-506: A Multitasker in Suppression of the Epithelial-to-Mesenchymal Transition

scientific article published on January 2014

Monitoring response to cytostatic cisplatin in a HER2(+) ovary cancer model by MRI and in vitro and in vivo MR spectroscopy.

scientific article published on 12 December 2013

One-Carbon Metabolism: Biological Players in Epithelial Ovarian Cancer

scientific article published on 19 July 2018

Ovarian Cancer Translational Activity of the Multicenter Italian Trial in Ovarian Cancer (MITO) Group: Lessons Learned in 10 Years of Experience

scientific article published on 07 April 2020

Ovarian cancer: a molecularly insidious disease

scientific article published in January 2015

Panning phage antibody libraries on cells: isolation of human Fab fragments against ovarian carcinoma using guided selection.

scientific article

Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells

scientific article published in August 2008

Possible targets on carcinoma for bMAb retargeting of lymphocyte or drug cytotoxicity

scientific article published on January 1, 1992

Preparation and biological characterization of conjugates consisting of ricin and a tumor-specific non-internalizing MAb.

scientific article published on January 1991

Redirected activity of human antitumor chimeric immune receptors is governed by antigen and receptor expression levels and affinity of interaction.

scientific article

Redirection of T-cell effector functions for cancer therapy: bispecific antibodies and chimeric antigen receptors

scientific article published on April 2013

Retargeting of human lymphocytes against human ovarian carcinoma cells by bispecific antibodies: from laboratory to clinic

scientific article

Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodies.

scientific article published in June 2003

Role of cytokines in cancer cachexia in a murine model of intracerebral injection of human tumours.

scientific article published in July 2001

Role of microRNAs in ovarian cancer pathogenesis and potential clinical implications

scientific article published on 24 December 2009

Sensitization of p53-mutated epithelial ovarian cancer to CD95-mediated apoptosis is synergistically induced by cisplatin pretreatment

scientific article published on February 2007

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.

scientific article published on 22 April 2013

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.

scientific article published on 7 February 2014

Subcellular Localization of Activated Leukocyte Cell Adhesion Molecule Is a Molecular Predictor of Survival in Ovarian Carcinoma Patients

scientific article published on 01 March 2008

T-DM1, a novel antibody-drug conjugate, is highly effective against uterine and ovarian carcinosarcomas overexpressing HER2.

scientific article

Targeting of T lymphocytes against EGF-receptor+ tumor cells by bispecific monoclonal antibodies: requirement of CD3 molecule cross-linking for T-cell activation

scientific article published on December 1993

Targeting of anti-tumor responses with bispecific antibodies.

scientific article published on August 1992

The ALCAM shedding by the metalloprotease ADAM17/TACE is involved in motility of ovarian carcinoma cells

scientific article published on December 2007

The Aspergillus toxin restrictocin is a suitable cytotoxic agent for generation of immunoconjugates with monoclonal antibodies directed against human carcinoma cells

scientific article published on 01 January 1989

The IL-18 antagonist IL-18-binding protein is produced in the human ovarian cancer microenvironment

scientific article published on 19 July 2013

Transfer of chimeric receptor gene made of variable regions of tumor-specific antibody confers anticarbohydrate specificity on T cells

article

UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines

scientific article

Unidirectional potentiation of binding between two anti-FBP MAbs: Evaluation of involved mechanisms

scientific article published on 01 May 1995

Use of anti-CD3 and anti-CD16 bispecific monoclonal antibodies for the targeting of T and NK cells against tumor cells

scientific article published on 01 January 1993

Use of combination of monoclonal antibodies directed against three distinct epitopes of a tumor-associated antigen: analysis of cell binding and internalization

scientific article published in May 1991

c-FLIPL expression defines two ovarian cancer patient subsets and is a prognostic factor of adverse outcome

scientific article published on 25 March 2009

miRNA control of apoptotic programs: focus on ovarian cancer

scientific article published on April 2011

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