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List of works by Gustavo Baldassarre

A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis

scientific article

A truncated form of teratocarcinoma-derived growth factor-1 (cripto-1) mRNA expressed in human colon carcinoma cell lines and tumors.

scientific article

Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas

scientific article published in January 2012

An Integrated Approach Identifies Mediators of Local Recurrence in Head and Neck Squamous Carcinoma.

scientific article published on 7 February 2017

Beneficial effects of intraoperative radiotherapy on tumor microenvironment could improve outcomes (Int J Radiat Oncol Biol Phys 2008;72:1575-1581).

scientific article published in July 2009

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC.

scientific article published on 15 September 2016

CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation

scientific article published on 04 August 2017

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells.

scientific article

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner

scientific article

Critical role of cyclin D3 in TSH-dependent growth of thyrocytes and in hyperproliferative diseases of the thyroid gland

scientific journal article

Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study.

scientific article published on 8 July 2016

Differential effects of protein kinase a sub-units on chinese-hamster-ovary cell cycle and proliferation

article

Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes

scientific article published on February 1993

Downregulation of miR-223 Expression Is an Early Event during Mammary Transformation and Confers Resistance to CDK4/6 Inhibitors in Luminal Breast Cancer

scientific article published on 20 December 2019

E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer

scientific article

Exploring the Role of Fallopian Ciliated Cells in the Pathogenesis of High-Grade Serous Ovarian Cancer

scientific article published on 24 August 2018

FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis

scientific article

Familial cancer associated with a polymorphism in ARLTS1

scientific article (publication date: 21 April 2005)

Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.

scientific article

Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo.

scientific article

HMGA1 positively regulates the microtubule-destabilizing protein stathmin promoting motility in TNBC cells and decreasing tumour sensitivity to paclitaxel

scientific article published on 03 May 2022

HMGA1 protein expression sensitizes cells to cisplatin-induced cell death

scientific article published on October 2005

HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas

scientific article published on 9 May 2003

Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice

scientific article published in March 2006

Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells

scientific article published on 21 December 2019

Infection with a transforming growth factor alpha anti-sense retroviral expression vector reduces the in vitro growth and transformation of a human colon cancer cell line

scientific article published on July 1993

Inhibition of breast cancer local relapse by targeting p70S6 kinase activity

scientific article published on 29 July 2013

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer

scientific article

Landscape of CDKN1B Mutations in Luminal Breast Cancer and Other Hormone-Driven Human Tumors

scientific article published on 17 July 2018

Linking inflammation to cell cycle progression.

scientific article published on January 2004

Loss of p27kip1 increases genomic instability and induces radio-resistance in luminal breast cancer cells.

scientific article

MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer

scientific article

Meet me in the cytoplasm: A role for p27(Kip1) in the control of H-Ras.

scientific article published on 08 April 2016

Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene

scientific article published on August 1999

Molecular biology of breast tumors and prognosis

scientific article

Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model

scientific article published on 02 September 2019

Mutant AKT1-E17K is oncogenic in lung epithelial cells

scientific article published on 25 May 2015

Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

scientific article

New light on p27kip1 in breast cancer ⬇️

scientific article published on August 16, 2012

Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway

scientific article published on 26 June 2001

Pivotal role of the RB family proteins in in vitro thyroid cell transformation

scientific article

Prognostic role of bowel involvement in optimally cytoreduced advanced ovarian cancer: a retrospective study

scientific article

Prostaglandin E2 inhibits proliferation and migration of HTR-8/SVneo cells, a human trophoblast-derived cell line.

scientific article published on 12 September 2005

RNA splicing alteration in the response to platinum chemotherapy in ovarian cancer: A possible biomarker and therapeutic target

scientific article published on 14 October 2020

Radiotherapy-induced miR-223 prevents relapse of breast cancer by targeting the EGF pathway.

scientific article published on 15 February 2016

Rat protein tyrosine phosphatase eta suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1).

scientific article published on December 2000

Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.

scientific article published on 17 February 2005

Regulation of BRCA1 transcription by specific single-stranded DNA binding factors

scientific article

Regulation of thymosin beta10 expression by TSH and other mitogenic signals in the thyroid gland and in cultured thyrocytes

scientific article published on June 1999

Role of T198 modification in the regulation of p27(Kip1) protein stability and function

scientific article

STAT3 in Breast Cancer Onset and Progression: A Matter of Time and Context

scientific article published on 18 September 2018

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.

scientific article published on 8 October 2015

Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells

scientific article published on 27 August 2020

Somatostatin as a regulator of first-trimester human trophoblast functions

scientific article published on 9 July 2008

Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity

scientific article published on 24 April 2020

Stathmin Is Required for Normal Mouse Mammary Gland Development and Δ16HER2-Driven Tumorigenesis

scientific article published on 26 November 2018

Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.

scientific article published on 27 February 2008

Stathmin is dispensable for tumor onset in mice

scientific article published on 20 September 2012

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.

scientific article published on 22 April 2013

Stathmin: a protein with many tasks. New biomarker and potential target in cancer ⬇️

scientific article published on 07 October 2011

TIMP-1 is Overexpressed and Secreted by Platinum Resistant Epithelial Ovarian Cancer Cells

scientific article published on 18 December 2019

Targeted intraoperative radiotherapy impairs the stimulation of breast cancer cell proliferation and invasion caused by surgical wounding

scientific article

The T197A Knock-in Model of Gene to Study the Effects of p27 Restoration

article

The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition.

scientific article

Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report

scientific article published on 10 December 2018

Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.

scientific article published in May 2005

USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability

scientific article published on 08 May 2019

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

scientific journal article

p27(kip1) functional regulation in human cancer: a potential target for therapeutic designs.

scientific article

p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis.

scientific article

p27kip1 at the crossroad between actin and microtubule dynamics

scientific article published on 01 April 2019

p27kip1 controls H-Ras/MAPK activation and cell cycle entry via modulation of MT stability.

scientific article

p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling

scientific article

p27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms.

scientific article published on 27 August 2016

p70S6 kinase mediates breast cancer cell survival in response to surgical wound fluid stimulation.

scientific article published on 12 March 2014

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