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List of works by Lorenza Rimassa

A Phase-1b study of tivantinib (ARQ 197) in adult patients with hepatocellular carcinoma and cirrhosis

scientific article published on 3 January 2013

A new nomogram for estimating survival in patients with brain metastases secondary to colorectal cancer

scientific article published on 4 September 2015

A phase II randomized dose escalation trial of sorafenib in patients with advanced hepatocellular carcinoma

scientific article published on 11 April 2013

A phase II randomized multicenter trial of gefitinib plus FOLFIRI and FOLFIRI alone in patients with metastatic colorectal cancer.

scientific article published on 30 July 2008

A randomized, multicenter, phase II study of vandetanib monotherapy versus vandetanib in combination with gemcitabine versus gemcitabine plus placebo in subjects with advanced biliary tract cancer: the VanGogh study

scientific article published on 23 December 2014

A validated prognostic classifier for V600EBRAF-mutated metastatic colorectal cancer: the 'BRAF BeCool' study

scientific article published on 19 July 2019

Activity and safety of NGR-hTNF, a selective vascular-targeting agent, in previously treated patients with advanced hepatocellular carcinoma.

scientific article

Adjuvant treatment of high-risk, radically resected gastric cancer patients with 5-fluorouracil, leucovorin, cisplatin, and epidoxorubicin in a randomized controlled trial.

scientific article published in April 2007

Adrenal metastases from adenocarcinoma of the esophagogastric junction: adrenalectomy and long-term survival

scientific article published on 01 August 2010

Alpha-fetoprotein screening in patients with hepatitis C-induced cirrhosis who achieved a sustained virologic response in the direct-acting antiviral agents era

scientific article published on 28 October 2018

An exploratory biomarker study in metastatic tumors from colorectal cancer patients treated with bevacizumab

scientific article published in January 2015

Angiogenesis inhibitors for advanced hepatocellular carcinoma: in search for the right partner

scientific article published on 01 November 2020

Antiangiogenic drugs currently used for colorectal cancer: what other pathways can we target to prolong responses?

scientific article published on June 2007

Assessment of Duration and Effects of 3 vs 6 Months of Adjuvant Chemotherapy in High-Risk Stage II Colorectal Cancer: A Subgroup Analysis of the TOSCA Randomized Clinical Trial

scientific article published on 13 February 2020

Assessment of HER2 status in patients with gastroesophageal adenocarcinoma treated with epirubicin-based chemotherapy: heterogeneity-related issues and prognostic implications

scientific article published on 16 August 2016

Assessment of Ramucirumab plus paclitaxel as switch maintenance versus continuation of first-line chemotherapy in patients with advanced HER-2 negative gastric or gastroesophageal junction cancers: the ARMANI phase III trial

scientific article published on 29 March 2019

Biliary Tract Cancers: Molecular Heterogeneity and New Treatment Options

scientific article published on 13 November 2020

Biomarkers in Hepatocellular Carcinoma--Letter

scientific article published on 02 August 2012

Budget impact of bimonthly use of cetuximab in patients diagnosed with metastatic colorectal cancer

scientific article published on 04 June 2019

CK7 and consensus molecular subtypes as major prognosticators in V600EBRAF mutated metastatic colorectal cancer

scientific article published on 02 September 2019

COVID-19 and liver cancer clinical trials: not everything is lost

scientific article published on 20 May 2020

Cabozantinib for the treatment of hepatocellular carcinoma

scientific article published on 11 October 2019

Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma

article by Ghassan K Abou-Alfa et al published 5 July 2018 in The New England Journal of Medicine

Cabozantinib in combination with atezolizumab versus sorafenib in treatment-naive advanced hepatocellular carcinoma: COSMIC-312 Phase III study design

scientific article published on 03 June 2020

Cabozantinib in patients with hepatocellular carcinoma failing previous treatment with sorafenib

scientific article published on 17 June 2019

Capecitabine and Temozolomide versus FOLFIRI in RAS-Mutated, MGMT-Methylated Metastatic Colorectal Cancer

scientific article published on 18 November 2019

Case report of acute aortic dissection during treatment with capecitabine for a late recurrence of breast cancer

scientific article published on 11 June 2010

Clinical portrait of the SARS-CoV-2 epidemic in European cancer patients

scientific article published on 31 July 2020

Clinical significance of neuroendocrine phenotype in non-small-cell lung cancer ⬇️

scientific article published on January 1, 2001

Combined Low Densities of FoxP3+ and CD3+ Tumor-Infiltrating Lymphocytes Identify Stage II Colorectal Cancer at High Risk of Progression

scientific article published on 25 February 2019

Combined PD-1/VEGFR blockade: a new era of treatment for hepatocellular cancer

scientific article published on 16 December 2020

Derazantinib (ARQ 087) in advanced or inoperable FGFR2 gene fusion-positive intrahepatic cholangiocarcinoma

scientific article published on 13 November 2018

Detection of somatostatin receptor subtypes 2 and 5 by somatostatin receptor scintigraphy and immunohistochemistry: clinical implications in the diagnostic and therapeutic management of gastroenteropancreatic neuroendocrine tumors

scientific article published in September 2011

Diagnostic accuracy of ¹¹C-choline PET/CT in comparison with CT and/or MRI in patients with hepatocellular carcinoma.

scientific article published on 12 May 2015

Drugs in Development for Hepatocellular Carcinoma

article

Early intravenous administration of nutritional support (IVANS) in metastatic gastric cancer patients at nutritional risk, undergoing first-line chemotherapy: study protocol of a pragmatic, randomized, multicenter, clinical trial

scientific article published on 22 February 2020

Effect of Comorbidities in Stage II/III Colorectal Cancer Patients Treated With Surgery and Neoadjuvant/Adjuvant Chemotherapy: A Single-Center, Observational Study

scientific article published on 21 March 2018

Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity?

scientific article published on 13 April 2018

Estimating Survival Probabilities of Advanced Gastric Cancer Patients in the Second-Line Setting: The Gastric Life Nomogram

article

FOLFIRI and Cetuximab Every Second Week for First-Line Treatment of KRAS Wild-Type Metastatic Colorectal Cancer According to Phosphatase and Tensin Homolog Expression: A Phase II Study.

scientific article published on 6 March 2015

FOLFOX or CAPOX in Stage II to III Colon Cancer: Efficacy Results of the Italian Three or Six Colon Adjuvant Trial

article

Fatal Infusion Reaction to Cetuximab: The Need for Predictive Risk Factors and Safer Patient Selection

scientific article published on 20 June 2011

Final results of a phase II trial for stereotactic body radiation therapy for patients with inoperable liver metastases from colorectal cancer

scientific article published on 23 September 2014

Functional Investigation of the Tumoural Heterogeneity of Intrahepatic Cholangiocarcinoma by In Vivo PET-CT Navigation: A Proof-of-Concept Study

scientific article published in 2022

Gastric cancer: Translating novels concepts into clinical practice

scientific article published on 14 August 2019

Hepatocellular Carcinoma: A Global Disease in Need of Individualized Treatment Strategies

scientific article published on 01 June 2017

Hepatocellular Carcinoma: Therapeutic Guidelines and Medical Treatment

scientific article

Hepatotoxicity of immune check point inhibitors: Approach and management

scientific article published on 08 July 2019

High expression of HOXA13 correlates with poorly differentiated hepatocellular carcinomas and modulates sorafenib response in in vitro models

scientific article

High-dose chemotherapy as adjuvant treatment for high-risk primary breast cancer patients

scientific article published on 15 November 2005

Immune-based therapies for hepatocellular carcinoma

scientific article published on 10 March 2020

Immunotherapy in Hepatocellular Cancer Patients with Mild to Severe Liver Dysfunction: Adjunctive Role of the ALBI Grade

scientific article published on 10 July 2020

Immunotherapy in hepatobiliary tumors: search for the missing pieces of the puzzle

scientific article published on 01 February 2020

Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism

scientific article published on 7 November 2011

Intermediate-dose melphalan with stem-cell support in platinum-refractory ovarian cancer.

scientific article

International and multicenter real-world study of sorafenib-treated patients with hepatocellular carcinoma under dialysis

scientific article published on 14 March 2020

Irinotecan and raltitrexed: an active combination in advanced colorectal cancer

scientific article

Is there an oligometastatic state in pancreatic cancer? Practical clinical considerations raise the question

scientific article published on 18 December 2019

KRAS mutation in lung metastases from colorectal cancer: prognostic implications

scientific article published on 29 December 2015

Khorana score and thromboembolic risk in stage II-III colorectal cancer patients: a post hoc analysis from the adjuvant TOSCA trial

scientific article published on 20 January 2020

Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT.

scientific article published on 3 July 2013

Lenvatinib for the treatment of unresectable hepatocellular carcinoma: evidence to date

article

Maintenance Therapy With Panitumumab Alone vs Panitumumab Plus Fluorouracil-Leucovorin in Patients With RAS Wild-Type Metastatic Colorectal Cancer: A Phase 2 Randomized Clinical Trial

scientific article published on 03 July 2019

Management of adverse events associated with tyrosine kinase inhibitors: Improving outcomes for patients with hepatocellular carcinoma

scientific article published on 15 May 2019

MicroRNA-425-3p predicts response to sorafenib therapy in patients with hepatocellular carcinoma

scientific article published on 21 July 2014

Modulation of biliary cancer chemo-resistance through microRNA-mediated rewiring of the expansion of CD133+ cells

scientific article published on 26 December 2019

Molecular determinants of outcome in sorafenib-treated patients with hepatocellular carcinoma.

scientific article published on 9 April 2013

Molecular therapies for HCC: Looking outside the box

scientific article published on 01 February 2020

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

scientific article published on 24 March 2021

Navigating the new landscape of second-line treatment in advanced hepatocellular carcinoma

scientific article published on 20 May 2020

Negative Hyperselection of Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer Who Received Panitumumab-Based Maintenance Therapy

scientific article published on 20 September 2019

Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells

scientific article published on 18 February 2019

Novel Therapies for Hepatocellular Carcinoma

scientific article published on 20 October 2020

Optimized management of advanced hepatocellular carcinoma: four long-lasting responses to sorafenib

scientific article published on May 2011

Oral chemotherapy with doxifluridine and folinic acid in biliary tract cancer

scientific article published on 01 December 1995

Phase I pharmacokinetic and pharmacodynamic study of lapatinib in combination with sorafenib in patients with advanced refractory solid tumors

scientific article published on 09 November 2012

Phase II Study of Tivantinib and Cetuximab in Patients With KRAS Wild-type Metastatic Colorectal Cancer With Acquired Resistance to EGFR Inhibitors and Emergence of MET Overexpression: Lesson Learned for Future Trials With EGFR/MET Dual Inhibition

scientific article published on 14 February 2019

Phase II study of NGR-hTNF, a selective vascular targeting agent, in patients with metastatic colorectal cancer after failure of standard therapy

scientific article published on 12 August 2010

Post-registration experience of nivolumab in advanced hepatocellular carcinoma: an international study

scientific article published on 01 August 2020

Predictive Impact of Mucinous Tumors on the Clinical Outcome in Patients with Poorly Differentiated, Stage II Colon Cancer: A TOSCA Subgroup Analysis

scientific article published on 13 January 2020

Preoperative or Perioperative Docetaxel, Oxaliplatin, and Capecitabine (GASTRODOC Regimen) in Patients with Locally-Advanced Resectable Gastric Cancer: A Randomized Phase-II Trial

scientific article published on 29 September 2020

Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients

scientific article published on 24 June 2008

Prognostic factors in 868 advanced gastric cancer patients treated with second-line chemotherapy in the real world.

scientific article published on 27 December 2016

Prognostic value of the neutrophil-to-lymphocyte ratio in the ARQ 197-215 second-line study for advanced hepatocellular carcinoma

scientific article published on 22 January 2017

Progression of Colorectal Liver Metastases from the End of Chemotherapy to Resection: A New Contraindication to Surgery?

scientific article published on 27 February 2018

Ramucirumab as Second-Line Therapy in Metastatic Gastric Cancer: Real-World Data from the RAMoss Study

scientific article published on 27 March 2018

Rectal squamous cell carcinoma treated with chemoradiotherapy: report of six cases

scientific article

Regorafenib for the treatment of unresectable hepatocellular carcinoma.

scientific article published on 05 June 2017

Regorafenib in hepatocellular carcinoma: latest evidence and clinical implications.

scientific article published on 27 June 2018

Regorafenib in patients with refractory metastatic pancreatic cancer: a Phase II study (RESOUND)

scientific article published on 20 November 2019

SBRT in unresectable advanced pancreatic cancer: preliminary results of a mono-institutional experience.

scientific article published on 21 June 2013

Safety and efficacy of preoperative or postoperative chemotherapy for resectable pancreatic adenocarcinoma (PACT-15): a randomised, open-label, phase 2-3 trial.

scientific article

Sarcopenia as a predictor of survival in patients undergoing bland transarterial embolization for unresectable hepatocellular carcinoma

scientific article published on 17 June 2020

Second-line treatment efficacy and toxicity in older vs. non-older patients with advanced gastric cancer: A multicentre real-world study

scientific article published on 11 December 2018

Selecting patients for gastrectomy in metastatic esophago-gastric cancer: clinics and pathology are not enough.

scientific article published on 4 October 2017

Serum Markers of Bone Metastases in Postmenopausal Breast Cancer Patients Treated with Formestane

scientific article published on January 1, 1997

Serum alpha-fetoprotein levels and clinical outcome in the phase 3 CELESTIAL study of cabozantinib versus placebo in patients with advanced hepatocellular carcinoma

scientific article published on 07 July 2020

Serum microRNAs as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma

scientific article

Shaping the landscape of immune oncology in hepatocellular carcinoma

scientific article published on 03 June 2018

Sorafenib in Hepatitis C Virus-Negative Patients With Hepatocellular Carcinoma: Don't Throw the Baby Out With the Bathwater!

scientific article published on 4 May 2017

Sorafenib in patients with Child-Pugh class A and B advanced hepatocellular carcinoma: a prospective feasibility analysis

article

Sorafenib therapy in advanced hepatocellular carcinoma: the SHARP trial.

scientific article published in June 2009

Stereotactic Ablative Radiotherapy (SABR) in inoperable oligometastatic disease from colorectal cancer: a safe and effective approach

scientific article

Stereotactic Body Radiation Therapy as an Alternative Treatment for Patients with Hepatocellular Carcinoma Compared to Sorafenib: A Propensity Score Analysis

scientific article published on 12 July 2018

Systemic Treatment Options in Hepatocellular Carcinoma

scientific article published on 29 May 2019

Targeted agents for second-line treatment of advanced hepatocellular carcinoma

scientific article published on 01 October 2019

The efficacy of hybrid chemotherapy with intravenous oxaliplatin and folinic acid and intra-hepatic infusion of 5-fluorouracil in patients with colorectal liver metastases: a phase II study

scientific article published on 11 May 2007

The immune milieu of cholangiocarcinoma: From molecular pathogenesis to precision medicine

scientific article published on 09 March 2019

The present and the future landscape of treatment of advanced hepatocellular carcinoma.

scientific article published on July 2010

The role of hepatic metastases and pulmonary tumor burden in predicting survival after complete pulmonary resection for colorectal cancer.

scientific article published on 28 August 2012

Tivantinib (ARQ197) displays cytotoxic activity that is independent of its ability to bind MET--letter

scientific article published on 13 June 2013

Tivantinib for second-line treatment of MET-high, advanced hepatocellular carcinoma (METIV-HCC): a final analysis of a phase 3, randomised, placebo-controlled study

article

Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study.

scientific article

Tivantinib, a new option for second-line treatment of advanced hepatocellular carcinoma? The experience of Italian centers.

scientific article

Tivantinib: a new promising mesenchymal-epithelial transition factor inhibitor in the treatment of hepatocellular carcinoma

scientific article published on February 2013

Treatment Stage Migration Maximizes Survival Outcomes in Patients with Hepatocellular Carcinoma Treated with Sorafenib: An Observational Study

scientific article published on 16 September 2017

Tumor and circulating biomarkers in patients with second-line hepatocellular carcinoma from the randomized phase II study with tivantinib

scientific article published on 25 August 2016

Tumor biopsy and patient enrollment in clinical trials for advanced hepatocellular carcinoma.

scientific article published on April 2017

Tumor-associated macrophages and response to 5-fluorouracil adjuvant therapy in stage III colorectal cancer.

scientific article published on 12 July 2017

Tumor-derived prostaglandin E2 promotes p50 NF-κB-dependent differentiation of monocytic MDSC

scientific article published on 07 April 2020

Unexpected low efficacy of stealth liposomal doxorubicin (Caelyx) and vinorelbine in metastatic breast cancer

scientific article published in January 2003

Usefulness of alpha-fetoprotein response in patients treated with sorafenib for advanced hepatocellular carcinoma.

scientific article

Vaccination against SARS-CoV-2 protects from morbidity, mortality and sequelae from COVID19 in patients with cancer

Which choice of therapy when many are available? Current systemic therapies for advanced hepatocellular carcinoma

scientific article published on 29 January 2020

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