List of works by Hitoshi Takizawa

A comprehensive surface proteome analysis of myeloid leukemia cell lines for therapeutic antibody development.

scientific article published on 30 January 2014

Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia

scientific article published on 25 October 2019

Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates

scientific article published on 01 March 2021

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups

scientific article published on 17 March 2014

Bone marrow dendritic cell progenitors sense pathogens via Toll-like receptors and subsequently migrate to inflamed lymph nodes

scientific article published on 09 September 2011

Cutting Edge: LPS-Induced Emergency Myelopoiesis Depends on TLR4-Expressing Nonhematopoietic Cells

scientific article published on 14 May 2012

Demand-adapted regulation of early hematopoiesis in infection and inflammation

scientific article

Development of the hematopoietic system: Role of inflammatory factors

scientific article published on 27 March 2019

Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium

scientific article published on 01 December 2019

Dynamic regulation of hematopoietic stem cell cycling

scientific article published on 15 July 2011

Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation

scientific article (publication date: 14 February 2011)

Engineered humanized bone organs maintain human hematopoiesis in vivo.

scientific article published on 2 February 2018

Engineering of a functional bone organ through endochondral ossification

scientific article published on 11 February 2013

Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk.

scientific article

Enhanced thrombopoietin but not G-CSF receptor stimulation induces self-renewing hematopoietic stem cell divisions in vivo.

scientific article published on 4 May 2016

Ex vivo expansion of hematopoietic stem cells: mission accomplished?

scientific article published on 29 December 2011

Fas (CD95) expression in myeloid cells promotes obesity‐induced muscle insulin resistance

scientific article published on January 2014

Fate Distribution and Regulatory Role of Human Mesenchymal Stromal Cells in Engineered Hematopoietic Bone Organs

scientific article published on 07 August 2019

Genetic fingerprint defines hematopoietic stem cell pool size and function

scientific article published on 01 March 2020

Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals

scientific article

Hematopoietic stem cell response to inflammation.

scientific article published on August 2016

Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors

scientific article published on 10 May 2019

Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung

scientific article

Human hemato-lymphoid system mice: current use and future potential for medicine

scientific article

Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo

scientific article

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

scientific article published on July 2009

Impact of inflammation on early hematopoiesis and the microenvironment

scientific article published on 30 May 2017

In vivo divisional tracking of hematopoietic stem cells

scientific article published on August 2012

Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment

scientific article

Inflammation Regulates Haematopoietic Stem Cells and Their Niche

scientific article published on 21 January 2022

LPS-stimulated human bone marrow stroma cells support myeloid cell development and progenitor cell maintenance

scientific article published on 11 November 2015

Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

scientific article

Macrophage tolerance: CD47–SIRP-α–mediated signals matter

Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F.

scientific article

Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness

scientific article published on 19 July 2017

Roles of a conserved family of adaptor proteins, Lnk, SH2-B, and APS, for mast cell development, growth, and functions: APS-deficiency causes augmented degranulation and reduced actin assembly

scientific article published on 01 March 2004

Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation

scientific article published on 01 November 2018

Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.

scientific article

[Inflammation and early hematopoiesis]

scientific article published on 01 January 2018

iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity

scientific article published on 26 December 2019