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List of works by Anthony W. Purcell

A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism

scientific article

A Naturally Occurring Peptide with an Elementary Single Disulfide-Directed β-Hairpin Fold

scientific article published on 2 February 2016

A Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition

scientific article

A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals

scientific article published on 19 August 2020

A Systems Approach to Understand Antigen Presentation and the Immune Response.

scientific article published in January 2016

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

scientific article

A charged amino acid residue in the transmembrane/cytoplasmic region of tapasin influences MHC class I assembly and maturation.

scientific article

A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

scientific article published on 01 December 2019

A comprehensive analysis of constitutive naturally processed and presented HLA-C*04:01 (Cw4)-specific peptides.

scientific article published on 7 January 2014

A comprehensive analysis of peptides presented by HLA-A1.

scientific article

A comprehensive review and performance evaluation of bioinformatics tools for HLA class I peptide-binding prediction

scientific article published on 14 June 2019

A long, naturally presented immunodominant epitope from NY-ESO-1 tumor antigen: implications for cancer vaccine design

scientific article

A modular BAM complex in the outer membrane of the alpha-proteobacterium Caulobacter crescentus.

scientific article

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

scientific article

A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

scientific article

A novel strategy for the targeted analysis of protein and peptide metabolites

scientific article

A prominent role of PDIA6 in processing of misfolded proinsulin

scientific article published on 03 March 2016

A sensitive method for detecting proliferation of rare autoantigen-specific human T cells

scientific article

A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

scientific article

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity

scientific article

A structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule

scientific article

Acute experimental infection of bats and ferrets with Hendra virus: Insights into the early host response of the reservoir host and susceptible model species

scientific article published on 30 March 2020

Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation

scientific article published on 18 November 2019

Allelic polymorphism in the T cell receptor and its impact on immune responses

scientific article

Alternate antigen processing in the presence of gamma interferon may misdirect the immune recognition of cancer.

scientific article published on 4 November 2015

Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates

scientific article published on 25 March 2019

An emerging role for comprehensive proteome analysis in human pregnancy research

scientific article

An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant

scientific article

An open-source computational and data resource to analyze digital maps of immunopeptidomes

scientific article

Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection

scientific article

Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii

scientific article published on 16 December 2015

Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor

scientific article published on 21 May 2009

Application of quantitative proteomics technologies to the biomarker discovery pipeline for multiple sclerosis

scientific article published on January 2013

Assembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspS

scientific article

Assembly of the secretion pores GspD, Wza and CsgG into bacterial outer membranes does not require the Omp85 proteins BamA or TamA.

scientific article published on 14 May 2015

Association of stress proteins with autoantigens: a possible mechanism for triggering autoimmunity?

scientific article published on 01 May 2003

Avoidance of self-reactivity results in skewed CTL responses to rare components of synthetic immunogens

scientific article published on February 1998

Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system

scientific article published on 26 May 2020

Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease

scientific article

C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases

scientific article

CD1a on Langerhans cells controls inflammatory skin disease.

scientific article published on 22 August 2016

CD4+ T-Cell Deficiency in HIV Patients Responding to Antiretroviral Therapy Is Associated With Increased Expression of Interferon-Stimulated Genes in CD4+ T Cells

scientific article published on 17 October 2011

CD8<sup>+</sup> T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

scientific article published on 18 May 2021

CTL recognition of a bulged viral peptide involves biased TCR selection

scientific article published in September 2005

CTL recognition of an altered peptide associated with asparagine bond rearrangement. Implications for immunity and vaccine design

scientific article published on 01 August 1996

Can alpha- and beta-alanine containing peptides be distinguished based on the CID spectra of their protonated ions?

scientific article published on 12 September 2008

Characterization of the Antigen Processing Machinery and Endogenous Peptide Presentation of a Bat MHC Class I Molecule.

scientific article

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

article

Combined proteomic and transcriptomic interrogation of the venom gland of Conus geographus uncovers novel components and functional compartmentalization

scientific article published on 29 January 2014

Comparative Metabolomics and Transcriptomics Reveal Multiple Pathways Associated with Polymyxin Killing in Pseudomonas aeruginosa

scientific article published on 08 January 2019

Comparative Transcriptomics Highlights the Role of the Activator Protein 1 Transcription Factor in the Host Response to Ebolavirus

scientific article published on 20 September 2017

Comparison between the isocratic and gradient retention behaviour of polypeptides in reversed-phase liquid chromatographic environments

scientific article published on 01 August 1999

Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy

scientific article

Conformational effects in reversed-phase high-performance liquid chromatography of polypeptides I. Resolution of insulin variants

scientific article published on 01 September 1995

Conformational effects in reversed-phase high-performance liquid chromatography of polypeptides II. The role of insulin A and B chains in the chromatographic behaviour of insulin

scientific article published on 01 September 1995

Conserved Features in the Structure, Mechanism, and Biogenesis of the Inverse Autotransporter Protein Family

scientific article

Conserved motifs reveal details of ancestry and structure in the small TIM chaperones of the mitochondrial intermembrane space.

scientific article

Constitutive and inflammatory immunopeptidome of pancreatic β-cells

scientific article

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

scientific article published on 23 March 2010

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

scholarly article

Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells

scientific article published on 15 October 2015

Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiological substrate

scientific article

Determinant spreading: lessons from animal models and human disease

article

Differential Roles of Plasma Protein Corona on Immune Cell Association and Cytokine Secretion of Oligomeric and Fibrillar Beta-Amyloid

scientific article published on 22 October 2019

Direct quantitation of MHC-bound peptide epitopes by selected reaction monitoring

scientific article published on 20 May 2011

Discovery by proteogenomics and characterization of an RF-amide neuropeptide from cone snail venom

scientific article

Discovery of an archetypal protein transport system in bacterial outer membranes.

scientific article

Discovery of novel disease-specific and membrane-associated candidate markers in a mouse model of multiple sclerosis

scientific article published on 20 December 2013

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction

scholarly article

Dissecting the role of peptides in the immune response: theory, practice and the application to vaccine design

scientific article

Diversity of conotoxin gene superfamilies in the venomous snail, Conus victoriae

scientific article (publication date: 2014)

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells

scientific article published on 3 May 2017

Downregulation of MHC Class I Expression by Influenza A and B Viruses

scientific article published on 29 May 2019

Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex

scientific article published on 17 October 2011

Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.

scientific article published on 6 February 2017

Elucidation of functionally significant structural modifications by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry with post-source decay.

scientific article

Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function?

scientific article published on 19 April 2011

Employing proteomics in the study of antigen presentation: an update

scientific article published on 13 August 2018

Endogenous and exogenous factors contributing to the surface expression of HLA B27 on mutant APC.

scientific article

Enhancing tumor vaccines: catalyzing MHC class II peptide exchange

scientific article published on February 2010

Epitope discovery and their use in peptide based vaccines

scientific article published on January 2010

Epitope-specific TCR  repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides

scientific article

Experimental autoimmune encephalomyelitis (EAE) IN C57Bl/6 mice is not associated with astrogliosis

scientific article published on 06 November 2010

Expression and purification of the minor histocompatibility antigen, HA-1H generated in Escherichia coli

scientific article published on 27 February 2007

Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue

scientific article published on 5 March 2004

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

scientific article published on 29 February 2016

HIVed, a knowledgebase for differentially expressed human genes and proteins during HIV infection, replication and latency

scientific article

HLA Class II Specificity Assessed by High-Density Peptide Microarray Interactions

scientific article published on 01 June 2020

HLA peptide length preferences control CD8+ T cell responses

scientific article

HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people

scientific article published on 07 March 2022

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

scientific article published in Nature Communications

HLA-associated antiepileptic drug-induced cutaneous adverse reactions

scientific article published on 09 April 2019

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

scientific article

Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice.

scientific article

High molecular weight components of the injected venom of fish-hunting cone snails target the vascular system

scientific article published on 19 July 2013

High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance

scientific article

High-performance liquid chromatography of amino acids, peptides and proteins

scientific article published on 01 August 1989

High-performance liquid chromatography of amino acids, peptides and proteins

High-performance liquid chromatography of amino acids, peptides and proteins CXV. Thermodynamic behaviour of peptides in reversed-phase chromatography

scientific article published on 01 February 1992

High-performance liquid chromatography of amino acids, peptides, and proteins. 123. Dynamics of peptides in reversed-phase high-performance liquid chromatography

scientific article published on 01 November 1993

Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule

scientific article

Hormone-like peptides in the venoms of marine cone snails

scientific article published on 21 August 2015

Human CD8+ T cell cross-reactivity across influenza A, B and C viruses

scientific article published on 18 February 2019

Human Leukocyte Antigen (HLA) B27 Allotype-Specific Binding and Candidate Arthritogenic Peptides Revealed through Heuristic Clustering of Data-independent Acquisition Mass Spectrometry (DIA-MS) Data

scientific article

Human Plasma Protein Corona of Aβ Amyloid and Its Impact on Islet Amyloid Polypeptide Cross-Seeding

scientific article published on 21 January 2020

Human T-cells recognise N-terminally Fmoc-modified peptide

scientific article published in September 2003

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity

scientific article

Human leukocyte antigen-associated drug hypersensitivity

scientific article published on November 8, 2012

Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis

scientific article

Identification and synthesis of altered peptides modulating T cell recognition of a synthetic peptide antigen.

scientific article published on January 1995

Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins

scientific article

Identification of Native and Post-Translationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics

scientific article published on 13 February 2018

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex

scientific article published on September 2002

Identification of an I-Ad restricted peptide on the 65-kilodalton heat shock protein of Mycobacterium avium

scientific article published in December 2002

Immune responses to abacavir in antigen-presenting cells from hypersensitive patients.

scientific article

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

scientific article

Immunodominance hierarchies and gender bias in direct T(CD8)-cell alloreactivity

scientific article published on 18 December 2007

Immunology by numbers: quantitation of antigen presentation completes the quantitative milieu of systems immunology!

scientific article

Immunopeptidogenomics: Harnessing RNA-Seq to Illuminate the Dark Immunopeptidome

scientific article published on 10 September 2021

Immunopeptidomic analysis reveals that deamidated HLA-bound peptides arise predominantly from deglycosylated precursors

scientific article published on 01 May 2020

Immunopeptidomics Special Issue

scientific article published on 01 June 2018

Immunoproteomics: Mass spectrometry-based methods to study the targets of the immune response

scientific article (publication date: March 2004)

Impact of glycans on T-cell tolerance to glycosylated self-antigens

scientific article published on 15 July 2008

Improved peptide-MHC class II interaction prediction through integration of eluted ligand and peptide affinity data

scientific article published on 10 June 2019

In Immunopeptidomics We Need a Sniper Instead of a Shotgun

scientific article

Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses

scientific article published on 07 May 2018

Induction of amphipathic helical peptide structures in RP-HPLC

scientific article published on 01 May 1995

Ingestion of oats and barley in patients with celiac disease mobilizes cross-reactive T cells activated by avenin peptides and immuno-dominant hordein peptides

scientific article

Isolation and characterization of naturally processed MHC-bound peptides from the surface of antigen-presenting cells

scientific article published on 01 January 2004

Isolation of T cell receptors targeting recurrent neoantigens in hematological malignancies.

scientific article published on 13 July 2018

Kinetics of antigen expression and epitope presentation during virus infection.

scientific article

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations

scientific article published on 27 February 2005

Linear ubiquitination prevents inflammation and regulates immune signalling

scientific article

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

scientific article published on 20 February 2017

MHCpLogics: an interactive machine learning-based tool for unsupervised data visualization and cluster analysis of immunopeptidomes

scientific article published in 2024

MR1 presents microbial vitamin B metabolites to MAIT cells

scientific article

Mass spectrometry-based identification of MHC-bound peptides for immunopeptidomics

scientific article published on 15 May 2019

Membrane proteomics by high performance liquid chromatography-tandem mass spectrometry: Analytical approaches and challenges

scientific article published on 21 January 2013

MhcVizPipe: A Quality Control Software for Rapid Assessment of Small- to Large-Scale Immunopeptidome Datasets

scientific article published in 2022

Minimal Information About an Immuno-Peptidomics Experiment (MIAIPE).

scientific article published in June 2018

Mismatch in epitope specificities between IFNγ inflamed and uninflamed conditions leads to escape from T lymphocyte killing in melanoma.

scientific article published on 16 February 2016

Mitigating Human IAPP Amyloidogenesis In Vivo with Chiral Silica Nanoribbons

scientific article published on 07 October 2018

Modification of the cyclopropyl moiety of abacavir provides insight into the structure activity relationship between HLA-B*57:01 binding and T-cell activation

scientific article published on 09 October 2019

Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails

scientific article

Molecular chaperones are targets of autoimmunity in Ro(SS-A) immune mice

scientific article published on 01 February 1999

Molecular machinations of the MHC-I peptide loading complex

scientific article published on February 2008

Molecular markers of preterm labor in the choriodecidua

scientific article

More than one reason to rethink the use of peptides in vaccine design

scientific article published on May 2007

Most viral peptides displayed by class I MHC on infected cells are immunogenic

scientific article

Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion

scientific article

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

scientific article

New Approaches to Investigate Drug-Induced Hypersensitivity

scientific article published on 2 November 2016

Nonprecipitating Anti-La(SS-B) Autoantibodies in Primary Sjögren's Syndrome

scientific article published on 01 June 1996

Novel strategy for identification of candidate cytotoxic T-cell epitopes from human preproinsulin

scientific article published in November 2003

Optimization of the MHC class I peptide cargo is dependent on tapasin

scientific article (publication date: April 2002)

Overlapping Peptides Elicit Distinct CD8+ T Cell Responses following Influenza A Virus Infection

scientific article published on 31 August 2020

Pancreatic Beta Cells Are Highly Susceptible to Oxidative and ER Stresses during the Development of Diabetes

article

Peptidomimetics: modifying peptides in the pursuit of better vaccines

scientific article published on February 1, 2011

Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes

scientific article

Physical and Toxicological Profiles of Human IAPP Amyloids and Plaques

scientific article published on 22 November 2018

Post-translationally modified T cell epitopes: immune recognition and immunotherapy

scientific article published on 08 September 2009

Posttranslational modifications of proteins in type 1 diabetes: the next step in finding the cure?

scientific article published on August 2012

Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

scholarly article

Preemptive priming readily overcomes structure-based mechanisms of virus escape

scientific article

Prevention of Cytotoxic T Cell Escape Using a Heteroclitic Subdominant Viral T Cell Determinant

scientific article

Probing the Binding Behavior and Conformational States of Globular Proteins in Reversed-Phase High-Performance Liquid Chromatography

scientific article published on 01 July 1999

Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+T Cells Infiltrate Islets in Type 1 Diabetes

scientific article published on 25 August 2014

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

scientific article

Protein secretion and outer membrane assembly in Alphaproteobacteria

scientific article

Proteomic interrogation of venom delivery in marine cone snails: novel insights into the role of the venom bulb

scientific article published on 29 September 2010

Qualitative and quantitative differences in peptides bound to HLA-B27 in the presence of mouse versus human tapasin define a role for tapasin as a size-dependent peptide editor

scientific article published on June 2005

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses

scientific article published on 28 June 2019

Quantifying epitope presentation using mass spectrometry

scientific article published on 25 June 2015

Quantitative and qualitative influences of tapasin on the class I peptide repertoire.

scientific article

Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain

scientific article published on 06 January 2014

Quokka: a comprehensive tool for rapid and accurate prediction of kinase family-specific phosphorylation sites in the human proteome

scientific article published on 01 December 2018

RHybridFinder: An R package to process immunopeptidomic data for putative hybrid peptide discovery

scientific article published on 21 October 2021

RP-HPLC Binding Domains of Proteins

scientific article published on 01 December 1998

Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides

scientific article published on 8 March 2016

Rapid microscale in-gel processing and digestion of proteins using surface acoustic waves

scientific article

Reactivity with dichotomous determinants of Ro 60 stratifies autoantibody responses in lupus and primary Sjögren's syndrome

article

Refinement in the production and purification of recombinant HCMV IE1-pp65 protein for the generation of epitope-specific T cell immunity

scientific article published on 14 May 2008

Reply to Roudier et al.: HLA-DRB1 polymorphism, anti-citrullinated protein antibodies, and rheumatoid arthritis.

scientific article

Resourcing, annotating, and analysing synthetic peptides of SARS-CoV-2 for immunopeptidomics and other immunological studies

scientific article published on 14 April 2021

Response to Comment on "A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands"

scientific article published on 01 August 2019

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

scientific article

Restricted Specificity of Intermolecular Spreading to Endogenous La (SS-B) and 60 kDa Ro (SS-A) in Experimental Autoimmunity

scientific article published on 01 August 2002

Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA-B27 allotypes

scientific article

Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02:01 ligands

scientific article published on 17 March 2012

Simultaneous Quantification of Viral Antigen Expression Kinetics Using Data-Independent (DIA) Mass Spectrometry.

scientific article

Specialisation of the Venom Gland Proteome in Predatory Cone Snails Reveals Functional Diversification of the Conotoxin Biosynthetic Pathway

article

Specialized insulin is used for chemical warfare by fish-hunting cone snails.

scientific article

Spliced Peptides and Cytokine-Driven Changes in the Immunopeptidome of Melanoma

scientific article published on 16 September 2020

Spreading of the immune response from 52 kDaRo and 60 kDaRo to calreticulin in experimental autoimmunity

article

Stable isotope shifted matrices enable the use of low mass ion precursor scanning for targeted metabolite identification

scientific article published on 17 January 2011

Structural and Functional Correlates of Enhanced Antiviral Immunity Generated by Heteroclitic CD8 T Cell Epitopes

scientific article

Structural and biological basis of CTL escape in coronavirus-infected mice

scientific article

Structural and regulatory diversity shape HLA-C protein expression levels

scientific article

Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses

scientific article

Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-Resistant Pseudomonas aeruginosa

scientific article published on 03 October 2019

T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells

scientific article

T cell allorecognition via molecular mimicry

scientific article

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

scientific article published on 12 March 2018

T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo

scientific article published on September 2005

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease

scientific article published on 23 December 2019

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

scientific article published on 25 September 2005

T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8

scientific article published on 25 August 2021

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

scientific article published in November 2015

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

scientific article

T-cells behaving badly: structural insights into alloreactivity and autoimmunity

scientific article published on 12 August 2008

TAP genes and immunity

scientific article published in October 2004

Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length

scientific article published on 05 April 2018

Tapasin-mediated retention and optimization of peptide ligands during the assembly of class I molecules

scientific article

Tentacle Transcriptomes of the Speckled Anemone (Actiniaria: Actiniidae: Oulactis sp.): Venom-Related Components and Their Domain Structure

scientific article published on 24 January 2020

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance

scientific article

The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes.

scientific article published on 9 March 2009

The Accessibility of the Prosthetic Group Biotin during Monomeric Avidin Affinity Chromatography

scientific article published on 01 July 1996

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

article

The Choice of HLA-Associated Peptide Enrichment and Purification Strategy Affects Peptide Yields and Creates a Bias in Detected Sequence Repertoire

scientific article published on 02 May 2020

The Enantioselective Total Synthesis and Unambiguous Proof of the Absolute Stereochemistry of Pervilleine C

The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule

scientific article

The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes

scientific article published on 01 May 2019

The SysteMHC Atlas project

scientific article published on 29 July 2017

The Use of CRISPR/Cas9 Gene Editing to Confirm Congenic Contaminations in Host-Pathogen Interaction Studies

scientific article published on 19 March 2018

The beta cell immunopeptidome

scientific article published on January 2014

The cellular redox environment alters antigen presentation

scientific article

The central role played by peptides in the immune response and the design of peptide-based vaccines against infectious diseases and cancer.

scientific article

The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers

scientific article published on 15 November 2021

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

scientific article

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

scientific article

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in Rheumatoid Arthritis

scientific article published on 9 January 2018

The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule

scientific article published on 30 August 2017

The molecular basis of cross-reactivity in the Australian Snake Venom Detection Kit (SVDK).

scientific article published on 12 August 2007

The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function

scientific article published on 13 May 2020

The peptide-loading complex and ligand selection during the assembly of HLA class I molecules.

scientific article

The primary immune response to Vaccinia virus vaccination includes cells with a distinct cytotoxic effector CD4 T-cell phenotype.

scientific article published on 14 September 2016

The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody

scientific article

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state

scientific article

The protein import channel in the outer mitosomal membrane of Giardia intestinalis

scientific article published on 16 June 2009

The shaping of T cell receptor recognition by self-tolerance

scientific article

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

scientific article published on 14 October 2010

The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance

scientific article published in July 2004

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization

scientific article

The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework

scientific article published on 11 April 2019

The use of post-source decay in matrix-assisted laser desorption/ionisation mass spectrometry to delineate T cell determinants.

scientific article

The use of proteomics to understand antiviral immunity

scientific article published on 08 October 2018

Tracking protein aggregation and mislocalization in cells with flow cytometry

scientific article

Transcriptional signature in microglia associated with Aβ plaque phagocytosis

scientific article published on 21 May 2021

Tumors reveal their secrets to cytotoxic T cells

scholarly article

Use of proteomics to define targets of T-cell immunity

scientific article

Using mass spectrometry to monitor drug induced changes in antigen presentation by the human leukocyte antigen

scientific article

Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response

scientific article published in Nature Communications

β2-glycoprotein I and protection from anti-SSA/Ro60-associated cardiac manifestations of neonatal lupus

scientific article