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List of works by Jan J. Enghild

"Ant-egg" cataract revisited.

scientific article published on 5 November 2016

A New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain A

scientific article

A Novel Biological Role for Peptidyl-Arginine Deiminases: Citrullination of Cathelicidin LL-37 Controls the Immunostimulatory Potential of Cell-Free DNA.

scientific article published on 23 February 2018

A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke

scientific article published in October 2002

A common polymorphism in extracellular superoxide dismutase affects cardiopulmonary disease risk by altering protein distribution.

scientific article

A dataset of human cornea proteins identified by Peptide mass fingerprinting and tandem mass spectrometry

scientific article

A new pathway of staphylococcal pathogenesis: apoptosis-like death induced by Staphopain B in human neutrophils and monocytes

scientific article published on 2 December 2008

A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037

scientific article

A unique loop extension in the serine protease domain of haptoglobin is essential for CD163 recognition of the haptoglobin-hemoglobin complex

scientific article published on 13 November 2006

ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1).

scientific article

Accumulation of beta ig-h3 gene product in corneas with granular dystrophy ⬇️

scientific article published on March 1, 1998

Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein

scientific article

Activation mechanisms of the precursors of matrix metalloproteinases 1, 2 and 3

scientific article published on January 1, 1992

Activation of Complement by Pigment Epithelium-Derived Factor in Rheumatoid Arthritis.

scientific article published on 21 June 2017

Adjuvant-free in vivo targeting. Antigen delivery by alpha 2-macroglobulin enhances antibody formation

scientific article published on 01 February 1994

Aldosterone and angiotensin II induce protein aggregation in renal proximal tubules

scientific article

Alpha-macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system

scientific article published on October 1990

Alpha1-microglobulin chromophores are located to three lysine residues semiburied in the lipocalin pocket and associated with a novel lipophilic compound.

scientific article

Alpha1-microglobulin is found both in blood and in most tissues

scientific article published in August 1998

Altered expression of extracellular superoxide dismutase in mouse lung after bleomycin treatment

scientific article published on 01 November 2001

Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing

scientific article published on 8 December 2003

An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients.

scientific article published on 15 March 2017

An examination of the inhibitory mechanism of serpins by analysing the interaction of trypsin and chymotrypsin with alpha 2-antiplasmin

scientific article published on May 1993

An unusual specificity in the activation of neutrophil serine proteinase zymogens

scientific article published on June 1990

Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement

scientific article published on 9 August 2017

Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmi

scientific article published on 01 February 1991

Angiostatin binds ATP synthase on the surface of human endothelial cells

scientific article

Angiostatin inhibits endothelial and melanoma cellular invasion by blocking matrix-enhanced plasminogen activation

scientific article published in May 1999

Antagonism between Staphylococcus epidermidis and Propionibacterium acnes and its genomic basis

scientific article

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

scientific article

Assignment of a single disulphide bridge in human alpha2-antiplasmin: implications for the structural and functional properties

scientific article published in May 1997

Atypical asymmetric lattice corneal dystrophy associated with a novel homozygous mutation (Val624Met) in the TGFBI gene.

scientific article

Author Correction: STEEP mediates STING ER exit and activation of signaling

scientific article published on 14 September 2020

Autocrine regulation of growth stimulation in human epithelial ovarian carcinoma by serine-proteinase-catalysed release of the urinary-type-plasminogen-activator N-terminal fragment

scientific article published in August 1999

Biochemical characterization of bovine plasma thrombin-activatable fibrinolysis inhibitor (TAFI).

scientific article

Biochemical importance of glycosylation of plasminogen activator inhibitor-1.

scientific article

Biosynthesis of bikunin proteins in the human carcinoma cell line HepG2 and in primary human hepatocytes. Polypeptide assembly by glycosaminoglycan

scientific article published on August 1995

Bovine corneal protein 54K (BCP54) is a homologue of the tumor-associated (class 3) rat aldehyde dehydrogenase (RATALD).

scientific article published on February 1991

Calbindin D28k Exhibits Properties Characteristic of a Ca2+ Sensor

scientific article published in Journal of Biological Chemistry

Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase

scientific article

Carbamylated LL-37 as a modulator of the immune response

scientific article published on 15 February 2016

Carbamylation of immunoglobulin abrogates activation of the classical complement pathway

scientific article

Catalytic properties of ADAM12 and its domain deletion mutants

scientific article published on 15 December 2007

Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology

scientific article published in July 2001

Characterisation of protein families in spider digestive fluids and their role in extra-oral digestion.

scientific article published on 10 August 2017

Characterization of the gila monster (Heloderma suspectum suspectum) venom proteome

scientific article published on 17 January 2015

Characterization of the gila monster (Heloderma suspectum suspectum) venom proteome

scientific article published on 13 February 2015

Clearance kinetics and matrix binding partners of the receptor for advanced glycation end products.

scientific article

Coagulation factor XIIIa substrates in human plasma: identification and incorporation into the clot

scientific article published on 17 January 2014

Combinatorial Biomolecular Nanopatterning for High-Throughput Screening of Stem-Cell Behavior.

scientific article published on 9 December 2015

Comparative genomic study of arachnid immune systems indicates loss of beta-1,3-glucanase-related proteins and the immune deficiency pathway.

scientific article

Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis

scientific article

Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene

scientific article

Complexes between serpins and inactive proteinases are not thermodynamically stable but are recognized by serpin receptors

scientific article published on 01 August 1994

Composition and proteolytic processing of corneal deposits associated with mutations in the TGFBI gene

scientific article

Conformation of the reactive site loop of alpha 1-proteinase inhibitor probed by limited proteolysis

scientific article published on 01 March 1992

Conservation of the Amyloid Interactome Across Diverse Fibrillar Structures

scientific article published on 07 March 2019

Corrigendum: Spider genomes provide insight into composition and evolution of venom and silk

scientific article published on 6 August 2014

Covalent complexes of antigen and alpha(2)-macroglobulin: evidence for dramatically-increased immunogenicity

scientific article published on 01 November 2001

Critical Influence of Cosolutes and Surfaces on the Assembly of Serpin-Derived Amyloid Fibrils.

scientific article

Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family

scientific article published on 31 May 2022

Degradation of interleukin 1beta by matrix metalloproteinases.

scientific article published on June 1996

Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization

scientific article published on 19 April 2005

Developmental expression of the receptor for advanced glycation end-products (RAGE) and its response to hyperoxia in the neonatal rat lung

scientific journal article

Diagnostic evaluation of a nanobody with picomolar affinity toward the protease RgpB from Porphyromonas gingivalis

scientific article

Differential Regulation of Extracellular Tissue Inhibitor of Metalloproteinases-3 Levels by Cell Membrane-bound and Shed Low Density Lipoprotein Receptor-related Protein 1 ⬇️

scientific article published on November 19, 2012

Differential expression and processing of transforming growth factor beta induced protein (TGFBIp) in the normal human cornea during postnatal development and aging

scientific article published on 26 September 2009

Disruption of gingipain oligomerization into non-covalent cell-surface attached complexes.

scientific article

Distal renal tubules are deficient in aggresome formation and autophagy upon aldosterone administration

scientific article

Disulfide Bond Pattern of Transforming Growth Factor β-Induced Protein

scientific article published on 8 September 2016

Divorcing folding from function: how acylation affects the membrane-perturbing properties of an antimicrobial peptide

scientific article published on 22 December 2009

Dynamic protein coronas revealed as a modulator of silver nanoparticle sulphidation in vitro

scientific article published on 09 June 2016

Early Events in the Amyloid Formation of the A546T Mutant of Transforming Growth Factor β-Induced Protein in Corneal Dystrophies Compared to the Nonfibrillating R555W and R555Q Mutants

scientific article published on 25 August 2015

Effects of elaidic acid on lipid metabolism in HepG2 cells, investigated by an integrated approach of lipidomics, transcriptomics and proteomics

scientific article

Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia

scientific article published in October 2002

Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase

scientific article published in October 2003

Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln

scientific article

Enzymatic and Structural Characterization of the Major Endopeptidase in the Venus Flytrap Digestion Fluid.

scientific article published on December 2015

Equine leukocyte elastase inhibitor. Primary structure and identification as a thymosin-binding protein

scientific article

Evidence against a blood derived origin for transforming growth factor beta induced protein in corneal disorders caused by mutations in the TGFBI gene

scientific article published on 27 June 2007

Evidence for a novel O-linked sialylated trisaccharide on Ser-248 of human plasminogen 2

scientific article published on 01 March 1997

Evidence for a two-step mechanism involved in the formation of covalent HC x TSG-6 complexes

scientific article published on 01 June 2006

Evidence that the platinum-reactive methionyl residue of the alpha 2-macroglobulin receptor recognition site is not in the carboxyl-terminal receptor binding domain

scientific article published on 01 May 1988

Evolutionary conservation of heavy chain protein transfer between glycosaminoglycans

scientific article published on 25 January 2010

Expression of a copper-containing amine oxidase by human ciliary body

scientific article published on September 8, 1998

Expression of a functional alpha-macroglobulin receptor binding domain in Escherichia coli.

scientific article

Extracellular superoxide dismutase (EC-SOD) binds to type i collagen and protects against oxidative fragmentation

scientific article published on 21 January 2004

Extracellular superoxide dismutase exists as an octamer.

scientific article published on 02 February 2006

Extracellular superoxide dismutase is present in secretory vesicles of human neutrophils and released upon stimulation.

scientific article published on 6 July 2016

Extracellular superoxide dismutase protects against matrix degradation of heparan sulfate in the lung

scientific article published on February 2008

Extracellular superoxide dismutase: structural and functional considerations of a protein shaped by two different disulfide bridge patterns.

scientific article

Factor XIIIa-derived peptides inhibit transglutaminase activity. Localization of substrate recognition sites.

scientific article published in October 1993

Familial subepithelial corneal amyloidosis--a lactoferrin-related amyloidosis

scientific article published on 01 December 1997

Fibril Core of Transforming Growth Factor Beta-Induced Protein (TGFBIp) Facilitates Aggregation of Corneal TGFBIp.

scientific article published on 6 May 2015

Flexibility of the Thrombin-activatable Fibrinolysis Inhibitor Pro-domain Enables Productive Binding of Protein Substrates

scientific article

Focus on molecules: Transforming growth factor beta induced protein (TGFBIp).

scientific article published on 23 December 2007

Formation of the alpha 1-microglobulin chromophore in mammalian and insect cells: a novel post-translational mechanism?

scientific article published on March 1995

Frequently used bioinformatics tools overestimate the damaging effect of allelic variants.

scientific article published on 4 December 2017

Functional amyloid in Pseudomonas

scientific article

Genomic and exoproteomic analyses of cold- and alkaline-adapted bacteria reveal an abundance of secreted subtilisin-like proteases

scientific article published in February 2016

Glucagon fibril polymorphism reflects differences in protofilament backbone structure

scientific article published on 12 February 2010

Hamster antithrombin III: purification, characterization and acute phase response

scientific article published on 01 September 1996

Heparin binding induces a conformational change in pigment epithelium-derived factor

scientific article published on 2 January 2007

Hepatocytes respond differently to major dietary trans fatty acid isomers, elaidic acid and trans-vaccenic acid

scientific article

Histologic distribution and biochemical properties of alpha 1-microglobulin in human placenta

scientific article

How Glycosaminoglycans Promote Fibrillation of Salmon Calcitonin

scientific article published on 8 June 2016

How glycosaminoglycans promote fibrillation of salmon calcitonin.

scientific article published on September 2017

Human Lysozyme Peptidase Resistance Is Perturbed by the Anionic Glycolipid Biosurfactant Rhamnolipid Produced by the Opportunistic Pathogen Pseudomonas aeruginosa

scientific article

Human complement C3 is a substrate for transglutaminases. A functional link between non-protease-based members of the coagulation and complement cascades

scientific article published on 04 June 2012

Human cornea proteome: identification and quantitation of the proteins of the three main layers including epithelium, stroma, and endothelium.

scientific article

Human extracellular superoxide dismutase is a tetramer composed of two disulphide-linked dimers: a simplified, high-yield purification of extracellular superoxide dismutase

scientific article

Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp

scientific article

Human procarboxypeptidase U, or thrombin-activable fibrinolysis inhibitor, is a substrate for transglutaminases. Evidence for transglutaminase-catalyzed cross-linking to fibrin

scientific article published on 01 October 1998

Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin

scientific article published on 01 November 1996

Human skin keratins are the major proteins in exhaled breath condensate

scientific article published on 01 February 2008

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

scientific article published in March 1996

Hydrogen exchange mass spectrometry as an analytical tool for the analysis of amyloid fibrillogenesis

scientific article published on April 2011

Hydrogen peroxide induce modifications of human extracellular superoxide dismutase that results in enzyme inhibition.

scientific article

Identification of a potential biomarker panel for the intake of the common dietary trans fat elaidic acid (trans∆9-C18:1).

scientific article

Identification of monomeric alpha-macroglobulin proteinase inhibitors in birds, reptiles, amphibians and mammals, and purification and characterization of a monomeric alpha-macroglobulin proteinase inhibitor from the American bullfrog Rana catesbeia

scientific article published on February 1993

Identification of transglutaminase reactive residues in human osteopontin and their role in polymerization

scientific article

Inactivation of epidermal growth factor by Porphyromonas gingivalis as a potential mechanism for periodontal tissue damage

scientific article published on 22 October 2012

Incorporation of pentraxin 3 into hyaluronan matrices is tightly regulated and promotes matrix cross-linking ⬇️

scientific article

Inhibition of Staphylococcus aureus cysteine proteases by human serpin potentially limits staphylococcal virulence

scientific article published on May 2011

Inhibition of gingipains by their profragments as the mechanism protecting Porphyromonas gingivalis against premature activation of secreted proteases

scientific article published on 10 April 2013

Insight into the Protein Composition of Immunoglobulin Light Chain Deposits of Eyelid, Orbital and Conjunctival Amyloidosis.

scientific article published on 21 April 2014

Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor

scientific article

Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications

scientific article

Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation

scientific article published on 06 March 2020

Inter-α-inhibitor impairs TSG-6-induced hyaluronan cross-linking

scientific article published on 04 September 2013

Interaction of human rheumatoid synovial collagenase (matrix metalloproteinase 1) and stromelysin (matrix metalloproteinase 3) with human alpha 2-macroglobulin and chicken ovostatin. Binding kinetics and identification of matrix metalloproteinase cl

scientific article published in May 1989

Investigating the biomarker potential of glycoproteins using comparative glycoprofiling - application to tissue inhibitor of metalloproteinases-1.

scientific article published on 28 December 2007

Investigations on collectin liver 1.

scientific article published on 27 June 2013

Isolation and characterization of fibronectin-alpha 1-microglobulin complex in rat plasma

scientific article published on August 1994

Isolation of a fibrin-binding fragment from blood coagulation factor XIII capable of cross-linking fibrin(ogen)

scientific article published on December 1988

KLIKK proteases of Tannerella forsythia: putative virulence factors with a unique domain structure

scientific article published on 21 April 2015

Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy

scientific article published on 11 January 2016

Kinetics and physiologic relevance of the inactivation of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, and antithrombin III by matrix metalloproteinases-1 (tissue collagenase), -2 (72-kDa gelatinase/type IV collagenase), and -3 (stromelys

scientific article published in August 1991

LASIK surgery of granular corneal dystrophy type 2 patients leads to accumulation and differential proteolytic processing of transforming growth factor beta-induced protein (TGFBIp).

scientific article published on 3 January 2016

Lack of the receptor for advanced glycation end-products attenuates E. coli pneumonia in mice

scientific article

Large scale isolation and purification of soluble RAGE from lung tissue

scientific article

Limited proteolysis of the alpha-macroglobulin rat alpha 1-inhibitor-3. Implications for a domain structure

scientific article published on 01 June 1991

MS Data Miner: a web-based software tool to analyze, compare, and share mass spectrometry protein identifications

scientific article

Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association

scientific article published on 10 September 2020

Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9

scientific journal article

Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures ⬇️

scientific article published on October 14, 1994

Matrix-degrading protease ADAMTS-5 cleaves inter-α-inhibitor and releases active heavy chain 2 in synovial fluids from arthritic patients

scientific article published on 04 September 2019

Mechanism of insulin incorporation into .alpha.2-macroglobulin: implications for the study of peptide and growth factor binding

scientific article published on 01 February 1991

Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin)

scientific journal article

Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix. ⬇️

scientific article

Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia

scientific article

Mirolysin, a LysargiNase from Tannerella forsythia, proteolytically inactivates the human cathelicidin, LL-37.

scientific article published on 20 December 2016

Miropin, a novel bacterial serpin from the periodontopathogen Tannerella forsythia, inhibits a broad range of proteases by using different peptide bonds within the reactive center loop

scientific article

Monodisperse and LPS-free Aggregatibacter actinomycetemcomitans leukotoxin: interactions with human β2 integrins and erythrocytes

scientific article published on 09 December 2012

Mouse extracellular superoxide dismutase: primary structure, tissue-specific gene expression, chromosomal localization, and lung in situ hybridization

scientific article published on October 1997

Murine extracellular superoxide dismutase is converted into the inactive fold by the Ser195Cys mutation

scientific article published on May 2013

Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization

scientific article

Mutation-Induced Deamidation of Corneal Dystrophy-Related Transforming Growth Factor β-Induced Protein

scientific article published on 15 November 2017

NH2-terminal amino acid sequence of rabbit hepatopoietin A, a heparin-binding polypeptide growth factor for hepatocytes

scientific article published on September 1989

NMR reveals two-step association of Congo Red to amyloid β in low-molecular-weight aggregates

scientific article

Near-complete 1H, 13C, 15N resonance assignments of dimethylsulfoxide-denatured TGFBIp FAS1-4 A546T.

scientific article

Neonatal plasminogen displays altered cell surface binding and activation kinetics. Correlation with increased glycosylation of the protein

scientific article published on July 1990

New Insights to Clathrin and Adaptor Protein 2 for the Design and Development of Therapeutic Strategies.

scientific article published on 10 December 2015

New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor.

scientific article published on July 2002

Off-pathway aggregation can inhibit fibrillation at high protein concentrations

scientific article published on 8 January 2013

Optimal control based NCO and NCA experiments for spectral assignment in biological solid-state NMR spectroscopy.

scientific article published on 7 July 2007

Optimized co-solute paramagnetic relaxation enhancement for the rapid NMR analysis of a highly fibrillogenic peptide.

scientific article published on 28 March 2015

P84-T Rapid and Individual-Specific Glycoprofiling of the Low-Abundant Plasma Protein Tissue Inhibitor of Metalloproteinases-1.

scientific article

Partial amino acid sequence determination of bovine corneal protein 54 K (BCP 54)

scientific article published in August 1990

Peptidyl arginine deiminase from Porphyromonas gingivalis abolishes anaphylatoxin C5a activity

scientific article

Physicochemical characterization of fish protein adlayers with bacteria repelling properties

scientific article published on 2 September 2012

Pigment-epithelium-derived factor (PEDF) occurs at a physiologically relevant concentration in human blood: purification and characterization

scientific article

Polymorphic fibrillation of the destabilized fourth fasciclin-1 domain mutant A546T of the Transforming growth factor-β-induced protein (TGFBIp) occurs through multiple pathways with different oligomeric intermediates.

scientific article

Post-translational modifications of human thrombin-activatable fibrinolysis inhibitor (TAFI): evidence for a large shift in the isoelectric point and reduced solubility upon activation

scientific article published in February 2006

Posttranslational Modifications of Human Inter-α-Inhibitor: Identification of Glycans and Disulfide Bridges in Heavy Chains 1 and 2 ⬇️

scientific article published on January 6, 1998

Potential clinical importance of the activation peptide of prostate-specific antigen

scientific article published on 20 June 2009

Preparation and electron paramagnetic resonance characterization of spin labeled monoderivatives of horse cytochrome c.

scientific article

Preparation of uniformly (13)C,(15)N-labeled recombinant human amylin for solid-state NMR investigation

scientific article published on 19 April 2014

Presence of the protein-glycosaminoglycan-protein covalent cross-link in the inter-alpha-inhibitor-related proteinase inhibitor heavy chain 2/bikunin ⬇️

scientific article published on April 25, 1993

Primary structure and tissue-specific expression of blue crab (Callinectes sapidus) metallothionein isoforms

scientific article

Protein Analysis of the TGFBIR124H Mouse Model Gives Insight into Phenotype Development of Granular Corneal Dystrophy

scientific article published on 18 June 2020

Protein Composition of TGFBI-R124C- and TGFBI-R555W-Associated Aggregates Suggests Multiple Mechanisms Leading to Lattice and Granular Corneal Dystrophy.

scientific article published on July 2015

Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.

scientific article

Proteolytic cleavage of the <scp>TGF</scp>β co‐receptor <scp>CD</scp>109 changes its conformation, resulting in protease inhibition via activation of its thiol ester, and dissociation from the cell membrane

scientific article published in 2024

Proteome analysis of human sebaceous follicle infundibula extracted from healthy and acne-affected skin

scientific article

Proteome reference maps of the Lotus japonicus nodule and root

scientific article published on 6 January 2014

Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury.

scientific article published on 23 January 2004

Proteomic analysis of the soluble fraction from human corneal fibroblasts with reference to ocular transparency

scientific article published on 30 March 2004

Proteomic investigation of the ventral rat hippocampus links DRP-2 to escitalopram treatment resistance and SNAP to stress resilience in the chronic mild stress model of depression

scientific article

Proteomic profiling of TGFBI-null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI-linked corneal dystrophies

scientific article published on 8 November 2017

Proteomics and the eye.

scientific article published on April 2014

Proteomics of Fuchs' endothelial corneal dystrophy support that the extracellular matrix of Descemet's membrane is disordered

scientific article

Prothrombin, albumin and immunoglobulin A form covalent complexes with alpha1-microglobulin in human plasma

scientific article (publication date: May 1997)

Purification and characterization of an alpha-macroglobulin proteinase inhibitor from the mollusc Octopus vulgaris

scientific article published on July 1992

Purification and characterization of extracellular superoxide dismutase in mouse lung

scientific article published on 01 August 2000

Purification and characterization of mouse soluble receptor for advanced glycation end products (sRAGE)

scientific journal article

Purification and structural characterization of transforming growth factor beta induced protein (TGFBIp) from porcine and human corneas.

scientific article published in December 2004

Purification, crystallization and preliminary X-ray diffraction of wild-type and mutant recombinant human transforming growth factor beta-induced protein (TGFBIp).

scientific article published on 26 February 2009

Rapid and individual-specific glycoprofiling of the low abundance N-glycosylated protein tissue inhibitor of metalloproteinases-1.

scientific article published on 6 January 2007

Reactive Center Loop Insertion in α-1-Antitrypsin Captured by Accelerated Molecular Dynamics Simulation

scientific article published on 20 December 2016

Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications ⬇️

scientific article

Recent cryogenic electron microscopy structures of human A2M may not be representative of the native protein

scientific article published in 2022

Regulation of insulin-like growth factor (IGF)-I action by matrix metalloproteinase-3 involves selective disruption of IGF-I/IGF-binding protein-3 complexes

scientific article published on 6 November 2003

Regulation of receptor for advanced glycation end products during bleomycin-induced lung injury

scientific article published on 01 September 2003

SAXS Models of TGFBIp Reveal a Trimeric Structure and Show That the Overall Shape Is Not Affected by the Arg124His Mutation

article

SILAC-MS Based Characterization of LPS and Resveratrol Induced Changes in Adipocyte Proteomics - Resveratrol as Ameliorating Factor on LPS Induced Changes

scientific article

STEEP mediates STING ER exit and activation of signaling

scientific article published on 20 July 2020

Secreted major Venus flytrap chitinase enables digestion of Arthropod prey

scientific article

Secretion of extracellular superoxide dismutase in neonatal lungs

scientific article published in November 2000

Serine protease HtrA1 accumulates in corneal transforming growth factor beta induced protein (TGFBIp) amyloid deposits

scientific article

Serum Amyloid P Component (SAP) Interactome in Human Plasma Containing Physiological Calcium Levels.

scientific article published on 18 January 2017

Silver staining of proteins on electroblotting membranes and intensification of silver staining of proteins separated by polyacrylamide gel electrophoresis

scientific article

Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins

scientific article published on 23 August 2018

Sodium dodecyl sulfate-stable complexes between serpins and active or inactive proteinases contain the region COOH-terminal to the reactive site loop

scientific article published on 01 June 1995

Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain

scientific article published on 19 June 2019

Species differences take shape at nanoparticles: protein corona made of the native repertoire assists cellular interaction.

scientific article published on 22 November 2013

Specific binding of urinary-type plasminogen activator (u-PA) to vitronectin and its role in mediating u-PA-dependent adhesion of U937 cells

scientific article published on May 1995

Spider genomes provide insight into composition and evolution of venom and silk

scientific article

Stable intermediates determine proteins' primary unfolding sites in the presence of surfactants

scientific article

Stepwise activation mechanisms of the precursors of matrix metalloproteinases 1 (tissue collagenase) and 3 (stromelysin)

scientific article published on 01 January 1991

Streptokinase and human fibronectin share a common epitope: implications for regulation of fibrinolysis and rheumatoid arthritis

scientific article published on 01 January 1993

Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies

scientific article

Structural and functional analysis of the spontaneous re-formation of the thiol ester bond in human alpha 2-macroglobulin, rat alpha 1-inhibitor-3 and chemically modified derivatives

scientific article published on September 1996

Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus

scientific article

Structural and functional characterization of tissue factor pathway inhibitor following degradation by matrix metalloproteinase-8.

scientific article published in October 2002

Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.

scientific article

Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1

scientific article

Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis

scientific article

Structure of inter-alpha-inhibitor (inter-alpha-trypsin inhibitor) and pre-alpha-inhibitor: current state and proposition of a new terminology

scientific article published on May 1, 1990

Substituting the Thiol Ester of Human A2M or C3 with a Disulfide Produces Native Proteins with Altered Proteolysis-Induced Conformational Changes

scientific article published on 10 December 2020

Substrate specificities and activation mechanisms of matrix metalloproteinases ⬇️

scientific article published on August 1, 1991

Synthesis and evaluation of silanediols as highly selective uncompetitive inhibitors of human neutrophil elastase

scientific article published on 28 August 2012

TSG-6 transfers proteins between glycosaminoglycans via a Ser28-mediated covalent catalytic mechanism

scientific article

Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins.

scientific article published on 20 July 2014

The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3.

scientific article

The C-terminal proteolytic processing of extracellular superoxide dismutase is redox regulated

scientific article published on 20 October 2011

The Compact and Biologically Relevant Structure of Inter-α-inhibitor Is Maintained by the Chondroitin Sulfate Chain and Divalent Cations

scientific article published on 4 January 2016

The Human Eye Proteome Project: perspectives on an emerging proteome

scientific article published on August 2013

The TSG-6 and I alpha I interaction promotes a transesterification cleaving the protein-glycosaminoglycan-protein (PGP) cross-link.

scientific article

The TSG-6/HC2-mediated transfer is a dynamic process shuffling heavy chains between glycosaminoglycans

scientific article published on 12 May 2010

The amido-pentadienoate-functionality of the rakicidins is a thiol reactive electrophile--development of a general synthetic strategy.

scientific article published in July 2015

The autolysis of human HtrA1 is governed by the redox state of its N-terminal domain

scientific article

The concentration of extracellular superoxide dismutase in plasma is maintained by LRP-mediated endocytosis

scientific article published on 27 June 2010

The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa

scientific article published on 31 July 2008

The diversity of FtsY-lipid interactions

scientific article published on 01 July 2010

The dual nature of human extracellular superoxide dismutase: one sequence and two structures.

scientific article

The effect of residue 1106 on the thioester-mediated covalent binding reaction of human complement protein C4 and the monomeric rat alpha-macroglobulin alpha 1 I3.

scientific article published on July 1995

The effects of hypochlorous acid and neutrophil proteases on the structure and function of extracellular superoxide dismutase

scientific article published on 9 January 2015

The essential Porphyromonas gingivalis type IX secretion system component PorZ delivers anionic-lipopolysaccharide to the PorU sortase for transpeptidase processing of cargos

scientific article published on 16 July 2020

The folding of human active and inactive extracellular superoxide dismutases is an intracellular event

scientific article published on 2 April 2008

The heparin-binding domain of extracellular superoxide dismutase is proteolytically processed intracellularly during biosynthesis.

scientific article

The high concentration of Arg213-->Gly extracellular superoxide dismutase (EC-SOD) in plasma is caused by a reduction of both heparin and collagen affinities

scientific article published on January 2005

The human cornea proteome: bioinformatic analyses indicate import of plasma proteins into the cornea

scientific article published on 9 May 2006

The insoluble TGFBIp fraction of the cornea is covalently linked via a disulfide bond to type XII collagen

scientific article

The intracellular proteolytic processing of extracellular superoxide dismutase (EC-SOD) is a two-step event

scientific article published on 24 March 2004

The intrinsic enzymatic activity of procarboxypeptidase U (TAFI) does not significantly influence the fibrinolytic rate: reply to a rebuttal

scientific article published on 01 June 2007

The major allergen from birch tree pollen, Bet v 1, binds and permeabilizes membranes.

scientific article

The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin.

scientific article published on September 1997

The neuroendocrine protein 7B2 is intrinsically disordered

scientific article

The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain

scientific article published on 23 March 2016

The paradigm that all oxygen-respiring eukaryotes have cytosolic CuZn-superoxide dismutase and that Mn-superoxide dismutase is localized to the mitochondria does not apply to a large group of marine arthropods

scientific article published in October 1997

The potential role of alpha 2-macroglobulin in the control of cysteine proteinases (gingipains) from Porphyromonas gingivalis

scientific article published on 01 January 1997

The primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin

scientific article published on February 1995

The protein composition of the digestive fluid from the venus flytrap sheds light on prey digestion mechanisms

scientific article

The proteome of seed development in the model legume Lotus japonicus.

scientific article

The role of higher-order protein structure in supporting binding by heteroclitic monoclonal antibodies: the monoclonal antibody KIM185 to CD18 also binds C4-binding protein

scientific article

The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.

scientific article published on 28 February 2014

The role of the receptor for advanced glycation end-products in a murine model of silicosis

scientific article

The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation

scientific article published on 13 June 2019

The spider hemolymph clot proteome reveals high concentrations of hemocyanin and von Willebrand factor-like proteins

scientific article published on 24 November 2015

The structure of rabbit extracellular superoxide dismutase differs from the human protein.

scientific article

The subunit composition of human extracellular superoxide dismutase (EC-SOD) regulates enzymatic activity

scientific article

The transfer of heavy chains from bikunin proteins to hyaluronan requires both TSG-6 and HC2.

scientific article published on 29 April 2008

Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase

scientific article published on 30 November 2006

Transcriptome analysis of the response of Burmese python to digestion.

scientific article published on August 2017

Transfer of inter-alpha-inhibitor heavy chains to hyaluronan by surface-linked hyaluronan-TSG-6 complexes

scientific article

Transforming growth factor beta induced protein accumulation in granular corneal dystrophy type III (Reis-Bücklers dystrophy). Identification by mass spectrometry in 15 year old two-dimensional protein gels

scientific article published on 20 August 2003

Transglutaminase 2-Catalyzed Intramolecular Cross-Linking of Osteopontin.

scientific article published on 17 December 2015

Unconditioned commercial embryo culture media contain a large variety of non-declared proteins: a comprehensive proteomics analysis

scientific article published on 27 August 2014

Unique structural features facilitate lizard tail autotomy

scientific article

Vesicular signalling and immune modulation as hedonic fingerprints: proteomic profiling in the chronic mild stress depression model

scientific article

Widespread abundance of functional bacterial amyloid in mycolata and other gram-positive bacteria

scientific article published on 24 April 2009

Zymogen activation specificity and genomic structures of human neutrophil elastase and cathepsin G reveal a new branch of the chymotrypsinogen superfamily of serine proteinases

scientific article published on January 1, 1991

alpha 1-Microglobulin destroys the proteinase inhibitory activity of alpha 1-inhibitor-3 by complex formation

scientific article published on 01 March 1995

alpha-Macroglobulins: detection and characterization

scientific article published on 01 January 1993

α-Synucleins from Animal Species Show Low Fibrillation Propensities and Weak Oligomer Membrane Disruption

scientific article published on 15 August 2018

α2-macroglobulin-like protein 1 can conjugate and inhibit proteases through their hydroxyl groups, due to an enhanced reactivity of its thiol ester

scientific article published on 25 September 2020

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