List of works by Norbert Perrimon

"ISN't Thirst Sweet?" Says the Fly.

scientific article

A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.

scientific article published on 3 February 2016

A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding

scientific article

A Drosophila model of oral peptide therapeutics for adult Intestinal Stem Cell tumors

scientific article published on 15 June 2020

A Drosophila resource of transgenic RNAi lines for neurogenetics

scientific article

A Mechanism Coupling Systemic Energy Sensing to Adipokine Secretion

scientific article

A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila

scientific article published on 04 October 2018

A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila

scientific article

A cell atlas of the adult Drosophila midgut

scientific article published on 08 January 2020

A computational framework for boosting confidence in high-throughput protein-protein interaction datasets

scientific article

A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling.

scientific article published in November 2006

A functional genomic analysis of cell morphology using RNA interference

scientific article

A gene-specific T2A-GAL4 library for Drosophila.

scientific article published on 22 March 2018

A genome-scale shRNA resource for transgenic RNAi in Drosophila

scientific article

A genome-wide CRISPR screen identifies the glycosylation enzyme DPM1 as a modifier of DPAGT1 deficiency and ER stress

scientific article published on 4 December 2021

A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression

scholarly article

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

scientific article published on 20 November 2005

A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint

scientific article

A genome-wide gene function prediction resource for Drosophila melanogaster

scientific article

A genome-wide transgenic resource for conditional expression of Drosophila microRNAs

scientific article

A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila

scientific article published on 25 January 2010

A rapid genome-wide microRNA screen identifies miR-14 as a modulator of Hedgehog signaling

scientific article

A regulatory network of Drosophila germline stem cell self-renewal

scientific article published on February 2014

A role for actomyosin contractility in Notch signaling

scientific article published on 11 February 2019

A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes

scientific article published on 9 June 2013

A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway

scientific article published on November 2003

A sharp end to sugary Wingless travels

scientific article

A single-cell survey of Drosophila blood

scientific article published on 12 May 2020

A systems-level interrogation identifies regulators of Drosophila blood cell number and survival

scientific article

A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs

scientific article published on 17 June 2015

Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity with CRISPR.

scientific article published in October 2017

Activation of posterior gap gene expression in the Drosophila blastoderm.

scientific article published in July 1995

Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper

scientific article

Activin signaling mediates muscle-to-adipose communication in a mitochondria dysfunction-associated obesity model

scientific article published on 24 July 2017

All for one, and one for all: the clonality of the intestinal stem cell niche

scientific article

An Evolutionarily Conserved Role of Presenilin in Neuronal Protection in the Aging Drosophila Brain

scientific article published on 11 May 2017

An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna

scientific article published on 16 May 2019

An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling

scientific article published on September 2016

An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms

scientific article published on 01 November 2019

An endogenous small interfering RNA pathway in Drosophila

scientific article

An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling

scientific article published on 29 April 2008

An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity

scientific article published on 18 December 2019

An integrative approach to ortholog prediction for disease-focused and other functional studies

scientific article

Analysis of twenty-four Gal4 lines in Drosophila melanogaster.

scientific article published in September 2002

Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly

scientific article published on 13 August 2019

Apicobasal polarization: epithelial form and function.

scientific article published on December 2003

Applications of high-throughput RNA interference screens to problems in cell and developmental biology

scientific article published on January 2007

Approaches to identify genes involved in Drosophila embryonic CNS development

scientific article

Author Correction: Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos

scientific article published on 30 March 2022

Author Correction: Efficient proximity labeling in living cells and organisms with TurboID

scientific article published on 01 January 2020

BIOSAFETY. Safeguarding gene drive experiments in the laboratory

scientific article

BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary

scientific article published in November 2005

BioLitMine: Advanced Mining of Biomedical and Biological Literature About Human Genes and Genes from Major Model Organisms

scientific article published on 07 October 2020

BioLitMine: advanced mining of biomedical and biological literature about human genes and genes from major model organisms

scientific article published on 17 July 2020

Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos

scientific article published on 24 November 2021

Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes

CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila

scientific article published on 30 June 2020

CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila.

scientific article

COPI activity coupled with fatty acid biosynthesis is required for viral replication

scientific article

CRISPR guide RNA design for research applications

scientific article published in September 2016

CRISPR-based engineering of gene knockout cells by homology-directed insertion in polyploid Drosophila S2R+ cells

scientific article published on 21 September 2020

Cas9-Mediated Genome Engineering in Drosophila melanogaster

scientific article

Cas9-based genome editing in Drosophila.

scientific article published in January 2014

Cellular functions of proteoglycans--an overview.

scientific article

Cellular phenotype recognition for high-content RNA interference genome-wide screening

scientific article published on January 2008

Cellular processes associated with germ band retraction in Drosophila.

scientific article published in August 2002

Collective nomenclature for LAP proteins

scientific article published in July 2000

Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos

scientific article

Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype.

scientific article

Comparative analysis of argonaute-dependent small RNA pathways in Drosophila

scientific article

Comparative analysis of the transcriptome across distant species

scientific article

Comparing CRISPR and RNAi-based screening technologies.

scientific article published in June 2016

Comparison of Cas9 activators in multiple species

scientific article published on 23 May 2016

Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer

scientific article published on 21 February 2013

Components of wingless signalling in Drosophila.

scientific article published in January 1994

Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3'UTRs

scientific article

Conserved phosphorylation hotspots in eukaryotic protein domain families

scientific article published on 29 April 2019

Conserved regulators of nucleolar size revealed by global phenotypic analyses

scientific article

Continuous muscle, glial, epithelial, neuronal, and hemocyte cell lines for Drosophila research

scientific article published on 19 January 2023

Control of Lipid Metabolism by Tachykinin in Drosophila

scientific article published on 01 February 2020

Control of lipid metabolism by tachykinin in Drosophila.

scientific article published on 25 September 2014

Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.

scientific article published on 23 August 2012

Control of the mitotic cleavage plane by local epithelial topology

scientific article

Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets

scientific article published on 18 April 2016

Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis

scientific article

Coordinated control of Notch/Delta signalling and cell cycle progression drives lateral inhibition-mediated tissue patterning.

scientific article published on 25 May 2016

Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila

scientific article published on 25 September 2013

Cross-species RNAi rescue platform in Drosophila melanogaster

scientific article published on 31 August 2009

Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells

scientific article published on 16 February 2021

Culture of Drosophila primary cells dissociated from gastrula embryos and their use in RNAi screening.

scientific article published on 24 September 2009

Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

scientific article published in July 1999

Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence

scientific article

Defining the interorgan communication network: systemic coordination of organismal cellular processes under homeostasis and localized stress

scientific article

Depleting gene activities in early Drosophila embryos with the "maternal-Gal4-shRNA" system

scientific article

Design and Generation of Donor Constructs for Genome Engineering in Drosophila

scientific article published in September 2016

Design and Generation of Drosophila Single Guide RNA Expression Constructs

scientific article published in September 2016

Design and implementation of high-throughput RNAi screens in cultured Drosophila cells

scientific article

Detection of Indel Mutations in Drosophila by High-Resolution Melt Analysis (HRMA).

scientific article

Development of an optimized synthetic Notch receptor as an in vivo cell-cell contact sensor

scientific article published on 10 May 2017

Developmental biology. Fishing for morphogens.

scientific article published in May 2001

Developmental biology. Sending all the right signals.

scientific article published in November 1998

Developmental biology: Our fly cousins' gut.

scientific article published in July 2008

Developmental roles of heparan sulfate proteoglycans in Drosophila

scientific article

Differential requirement for STAT by gain-of-function and wild-type receptor tyrosine kinase Torso in Drosophila.

scientific article

Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices

scientific article

Discovery of progenitor cell signatures by time-series synexpression analysis during Drosophila embryonic cell immortalization.

scientific article

Dissection of the Torso signal transduction pathway in Drosophila.

scientific article published on December 1995

Diversity and dynamics of the Drosophila transcriptome

scientific article

Do-it-yourself RNAi made easy?

article by Bernard Mathey-Prevot & Norbert Perrimon published April 2007 in Nature Methods

Downregulation of the tyrosine degradation pathway extends <i>Drosophila</i> lifespan

scientific article published on 15 December 2020

Droplet microfluidic technology for single-cell high-throughput screening

scientific article

Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity

scientific article published on 27 October 2020

Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection

scientific article

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.

scientific article published in December 2001

Drosophila Wnt/Fz pathways.

scientific article published on 10 May 2005

Drosophila and the genetics of the internal milieu

scientific article published on November 2007

Drosophila as a Model for Tumor-Induced Organ Wasting

scientific article published on 01 January 2019

Drosophila as a model for context-dependent tumorigenesis

scientific article

Drosophila as a model for interorgan communication: lessons from studies on energy homeostasis

scientific article published on July 2011

Drosophila as a model for studying cystic fibrosis pathophysiology of the gastrointestinal system

scientific article published on 28 April 2020

Drosophila as a model system to study autophagy

scientific article published on 27 August 2010

Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion

scientific article

Drosophila developmental biology methods

scientific article published in June 2014

Drosophila heparan sulfate, a novel design

scientific article

Drosophila melanogaster: a simple system for understanding complexity

scientific article published on 27 September 2019

Drosophila wingless: a paradigm for the function and mechanism of Wnt signaling

scientific article published on June 1994

Drug-target identification in Drosophila cells: combining high-throughout RNAi and small-molecule screens

scientific article published on 30 October 2006

Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events

scientific article

Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling

scientific article

ESCRT factors restrict mycobacterial growth

scholarly article

Ecdysone signaling at metamorphosis triggers apoptosis of Drosophila abdominal muscles

scientific article published on 17 September 2013

Efficient proximity labeling in living cells and organisms with TurboID

scientific article published on 20 August 2018

Embryonic multipotent progenitors remodel theDrosophilaairways during metamorphosis ⬇️

scientific article published on November 1, 2010

Endocrine Regulation of Energy Balance by Drosophila TGF-β/Activins

scientific article published on 28 September 2018

Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila

scientific article

Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis

scientific article published on 14 December 2003

Erratum: Integrating protein-protein interaction networks with phenotypes reveals signs of interactions

scholarly article published in Nature Methods

Erratum: wingless refines its own expression domain on the Drosophila wing margin

scientific article published in Nature

Evidence for engrailed-independent wingless autoregulation in Drosophila.

scientific article published in August 1995

Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays

scientific article

Evidence that stem cells reside in the adult Drosophila midgut epithelium.

scientific article published on 7 December 2005

Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.

scientific article published on 7 February 2011

Expanding the horizons of genome editing in the fruit fly with Cas12a

scientific article published on 03 September 2020

Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes

scientific article published on 2 March 2008

Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing

scientific article

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging ⬇️

scientific article published on November 24, 2010

False negative rates in Drosophila cell-based RNAi screens: a case study

scientific article

Fat Body p53 Regulates Systemic Insulin Signaling and Autophagy under Nutrient Stress via Drosophila Upd2 Repression

scientific article published on 01 October 2020

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

scientific article published on 4 March 2022

FlyPrimerBank: an online database for Drosophila melanogaster gene expression analysis and knockdown evaluation of RNAi reagents

scientific article published on 04 September 2013

FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update

scientific article

FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update

scientific article published on 23 October 2016

FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update

scientific article published on 26 October 2020

FlyRNAi: the Drosophila RNAi screening center database.

scientific article

Fruit flies on the front line: the translational impact of Drosophila

scientific article published on March 2016

Function of the ETS transcription factor Yan in border cell migration

scientific article published in August 2005

Functional genomic analysis of the Wnt-wingless signaling pathway

scientific article published on 07 April 2005

Functional genomics reveals genes involved in protein secretion and Golgi organization

scientific article published on February 2006

Functional screening identifies miR-315 as a potent activator of Wingless signaling

scholarly article

Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms

scientific article published on 25 September 2013

GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo

scientific article published on 22 August 2006

GLAD: an Online Database of Gene List Annotation for Drosophila

scientific article published on July 2015

Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.

scientific article published in November 2002

Gene Knock-Ins in Drosophila Using Homology-Independent Insertion of Universal Donor Plasmids

scientific article published on 04 November 2019

Gene2Function: An Integrated Online Resource for Gene Function Discovery

scientific article

Generating lineage-specific markers to study Drosophila development

scientific article published in January 1991

Genetic determinants of phosphate response in Drosophila

scientific article

Genetic odyssey to generate marked clones in Drosophila mosaics

scientific article published on 12 March 2014

Genetic screening for signal transduction in the era of network biology

scientific article published on January 2007

Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila

scientific article

Genome-wide RNAi analysis of growth and viability in Drosophila cells

scientific article

Genome-wide RNAi screen for host factors required for intracellular bacterial infection

scientific article published on 14 July 2005

Genome-wide RNAi screen reveals a role for the ESCRT complex in rotavirus cell entry

scientific article published on 03 June 2013

Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition

scientific article

Genome-wide high-throughput screens in functional genomics

scientific article

Genomic screening with RNAi: results and challenges

scientific article

HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species

scientific article published on 01 October 2019

Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning

scientific article

Hedgehog signal transduction: recent findings

scientific article

Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila

scientific article

Heparan sulphate proteoglycans: the sweet side of development

scientific article

Hierarchical rules for Argonaute loading in Drosophila

scientific article

High-throughput RNA interference screens in Drosophila tissue culture cells.

scientific article

High-throughput RNAi screening in cultured cells: a user's guide.

scientific article published in May 2006

High-throughput approaches to dissecting MAPK signaling pathways

scientific article published on November 2006

Highly efficient Cas9-mediated transcriptional programming

scientific article

Homeostasis in infected epithelia: stem cells take the lead

scientific article published on October 2009

Identification of adult midgut precursors in Drosophila

scientific article published on 23 September 2010

Identification of neural outgrowth genes using genome-wide RNAi

scientific article

Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi

scientific article

Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA).

scientific article published on 28 November 2017

In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila

scientific article

In vivo RNAi: today and tomorrow

scientific article

In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography.

scientific article published on 9 December 2007

In vivo study of gene expression with an enhanced dual-color fluorescent transcriptional timer

scientific article published on 29 May 2019

In vivo study of gene expression with an enhanced dual-color fluorescent transcriptional timer

scientific article

Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model

scientific article

Inducing RNAi in Drosophila cells by soaking with dsRNA.

scientific article published on May 2014

Inducing RNAi in Drosophila cells by transfection with dsRNA.

scientific article published on May 2013

Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen

scientific article

Integrated activity of PDZ protein complexes regulates epithelial polarity

scientific article

Integrating protein-protein interaction networks with phenotypes reveals signs of interactions.

scientific article

Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila

scientific article published on 11 February 2009

Intelligent Interfaces for Mining Large-Scale RNAi-HCS Image Databases

article published in 2007

Interorgan Communication Pathways in Physiology: Focus on Drosophila

scientific article published on 10 October 2016

Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells

scientific article published on 01 July 2019

Intertissue control of the nucleolus via a myokine-dependent longevity pathway

scientific article

Intestinal Stem Cells Exhibit Conditional Circadian Clock Function

Intestinal response to dietary manganese depletion in Drosophila

scientific article published on 04 December 2019

Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster

scientific article

Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled

scientific article published in November 1994

Krüppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes.

scientific article published on 22 March 2018

Large-Scale Transgenic Drosophila Resource Collections for Loss- and Gain-of-Function Studies

scientific article published on 18 February 2020

List of Contributors

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

scientific article published on February 2000

Loss-of-function genetic tools for animal models: cross-species and cross-platform differences

scientific article published on 31 October 2016

MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome

scientific article published on 03 May 2017

Mapping signaling pathway cross-talk in Drosophila cells

scientific article published on 15 August 2016

Matter arising: off-targets and genome-scale RNAi screens in Drosophila

scientific article published on January 2007

Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch

scientific article published on 4 June 2015

Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel

scientific article published on 7 February 2018

Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis

scientific article

Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.

scientific article published in September 2003

Mechanisms of muscle growth and atrophy in mammals and Drosophila

scientific article published on 24 October 2013

Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models

scientific article published on 02 October 2013

Mechanosensitive channels and their functions in stem cell differentiation

scientific article published on 28 November 2018

Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila

scientific article

Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species

scientific article published on 28 August 2019

Methods and tools for spatial mapping of single-cell RNAseq clusters in Drosophila

scientific article published on 15 April 2021

Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control

scientific article published in February 2017

Minimizing the risk of reporting false positives in large-scale RNAi screens

article

Modeling metabolic homeostasis and nutrient sensing in Drosophila: implications for aging and metabolic diseases

scientific article published on March 2014

Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data

scientific article

Molecular mechanisms of epithelial morphogenesis

scientific article

Morphogen diffusion: the case of the Wingless protein

Multiple roles for four-jointed in planar polarity and limb patterning

scientific article published in December 2000

Muscle mitohormesis promotes longevity via systemic repression of insulin signaling

scientific article published on 24 October 2013

Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E.

scientific article published on 29 August 2005

Next generation CRISPR/Cas9 transcriptional activation inDrosophilausing flySAM

scholarly article published 31 January 2018

Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM.

scientific article published on 16 April 2018

Next-generation large-scale binary protein interaction network for Drosophila

preprint published on 3 August 2022

No Evidence that Wnt Ligands Are Required for Planar Cell Polarity in Drosophila

scientific article published on 01 September 2020

Norbert Perrimon

scientific article published in July 2005

Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity

scientific article published on 16 March 2005

Of flies and men: insights on organismal metabolism from fruit flies

scientific article

Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway

scientific article published on July 2016

Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis

scientific article

Open questions: completing the parts list and finding the integrating signals

scientific article

Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes

scientific article published on 20 May 2021

Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9.

scientific article

Optimized strategy for in vivo Cas9-activation in Drosophila

scientific article published on 14 August 2017

Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca2+ signaling in the Drosophila midgut

scientific article published on 31 May 2017

PAPTi: a peptide aptamer interference toolkit for perturbation of protein-protein interaction networks

scientific article published on 29 January 2013

PPIRank - an advanced method for ranking protein-protein interations in TAP/MS data

scientific article

Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets

scientific article

Paralog Explorer: a resource for mining information about paralogs in common research organisms

scientific article published on 22 July 2022

Phosphorylation networks regulating JNK activity in diverse genetic backgrounds

scientific article published on October 2008

Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes.

scientific article published on 29 March 2018

Pooled CRISPR Screens in Drosophila Cells

scientific article published on 01 December 2019

Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in Drosophila cells

scientific article published on 10 December 2022

Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in cells

scientific article published on 20 April 2023

Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in cells

article

Presenilin affects arm/beta-catenin localization and function in Drosophila.

scientific article published in November 2000

Primary cell cultures from Drosophila gastrula embryos

scientific article published on 28 February 2011

Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by RNA-based isolation

scientific article published on 09 December 2019

Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform

scientific article published on 27 July 2009

Protein complex-based analysis framework for high-throughput data sets

scientific article

Protein visualization and manipulation in Drosophila through the use of epitope tags recognized by nanobodies

scientific article published on 25 January 2022

Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation

scientific article

Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling

scientific article

Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase

scientific article

Proteomics of protein trafficking by in vivo tissue-specific labeling

scientific article published on 22 April 2021

Proximity-dependent labeling methods for proteomic profiling in living cells

scientific article published on 7 April 2017

Proximity-dependent labeling methods for proteomic profiling in living cells: An update

scientific article published on 10 September 2020

Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3.

scientific article published in June 1990

Quantitative morphological signatures define local signaling networks regulating cell morphology.

scientific article

Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila.

scientific article published in January 1999

RNA interference screening in Drosophila primary cells for genes involved in muscle assembly and maintenance.

scientific article published in April 2008

RNAi screening comes of age: improved techniques and complementary approaches

scientific article

RNAi screening: new approaches, understandings, and organisms

scientific article

RNAiCut: automated detection of significant genes from functional genomic screens.

scientific article published in July 2009

Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling

scientific article published in February 2002

Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells

scientific article

Realizing the promise of RNAi high throughput screening

scientific article published on April 2010

Receptor tyrosine kinases in Drosophila development

scientific article published on June 2013

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

scientific article

Regulation of insulin and adipokinetic hormone/glucagon production in flies

scientific article published on 04 August 2019

Regulators of autophagosome formation in Drosophila muscles

scientific article

Requirement of the Drosophila raf homologue for torso function

scientific article published in November 1989

Resources for functional genomics studies in Drosophila melanogaster

scientific article (publication date: May 2014)

Retraction of the Drosophila germ band requires cell-matrix interaction.

scientific article

Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy

scientific article

Roles of major facilitator superfamily transporters in phosphate response in Drosophila

scientific article

Roles of myosin phosphatase during Drosophila development.

scientific article published in February 2003

SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth

scientific article published in December 2007

SNP-CRISPR: A Web Tool for SNP-Specific Genome Editing

scientific article published on 06 February 2020

SNP-CRISPR: a web tool for SNP-specific genome editing

preprint published on 19 November 2019

Sarcomere formation occurs by the assembly of multiple latent protein complexes

scientific article (publication date: November 2010)

Seipin is required for converting nascent to mature lipid droplets

scientific article

Sequential activation of signaling pathways during innate immune responses in Drosophila.

scientific article published on November 2002

Signaling in time and space

scientific article published on 2 April 2014

Signaling mechanisms controlling cell fate and embryonic patterning

scientific article published on August 2012

Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.

scientific article published in September 2003

Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila

scientific article published on 08 September 2020

Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila

scientific article

Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila

scientific article published in October 2004

Spatial and temporal organization of signaling pathways

scientific article

Spatial control of the actin cytoskeleton in Drosophila epithelial cells

scientific article

Specificities of heparan sulphate proteoglycans in developmental processes

scientific article

Stable Force Balance between Epithelial Cells Arises from F-Actin Turnover

scientific article

State-of-the-art CRISPR for in vivo and cell-based studies in Drosophila

scientific article published in May 2022

Steroids make you bigger? Fat chance says Myc.

scientific article published on July 2010

Stress signaling between organs in metazoa

scientific article published on 21 September 2015

Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes

scientific article published on 14 December 2011

Super-size flies

scientific article

Synergy between bacterial infection and genetic predisposition in intestinal dysplasia

scientific article

Synthetic Lethality Screens Using RNAi in Combination with CRISPR-based Knockout in Drosophila Cells. ⬇️

scientific article published on February 2017

Systematic screen of chemotherapeutics in Drosophila stem cell tumors

scientific article published on 10 March 2014

Systemic organ wasting induced by localized expression of the secreted insulin/IGF antagonist ImpL2.

scientific article published on April 2015

TIMEOR: a web-based tool to uncover temporal regulatory mechanisms from multi-omics data

scientific article published on 01 July 2021

Tailoring the genome: the power of genetic approaches

scientific article

Targeting metabolic pathways for extension of lifespan and healthspan across multiple species

scientific article published on 05 October 2020

Temperature-sensitive control of protein activity by conditionally splicing inteins

scientific article published on 6 June 2004

The Atg1-Tor pathway regulates yolk catabolism in Drosophila embryos

scientific article

The Drosophila Gene Expression Tool (DGET) for expression analyses.

scientific article

The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle.

scientific article

The Drosophila kekkon genes: novel members of both the leucine-rich repeat and immunoglobulin superfamilies expressed in the CNS.

scientific article published in August 1996

The Hippo signaling pathway interactome

scientific article

The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration

scientific article published in December 2010

The Jak/STAT pathway in model organisms: emerging roles in cell movement

scientific article

The Multidimensional Organization of Interorgan Communication Networks

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The PDGF/VEGF receptor controls blood cell survival in Drosophila

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The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling

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The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming.

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The Transgenic RNAi Project at Harvard Medical School: Resources and Validation.

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The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors.

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The circadian clock gates the intestinal stem cell regenerative state

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The emergence of geometric order in proliferating metazoan epithelia

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The era of systems developmental biology.

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The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila

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The homeobox transcription factor cut coordinates patterning and growth during Drosophila airway remodeling

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The influence of skeletal muscle on systemic aging and lifespan

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The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila

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The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Ftz.

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The orthodenticle gene is regulated by bicoid and torso and specifies Drosophila head development.

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The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling.

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The promise and perils of Wnt signaling through beta-catenin.

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The retinoic-like juvenile hormone controls the looping of left-right asymmetric organs in Drosophila.

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The role of translationally controlled tumor protein in proliferation of Drosophila intestinal stem cells

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The roles of JAK/STAT signaling in Drosophila immune responses

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The torso pathway in Drosophila: lessons on receptor tyrosine kinase signaling and pattern formation

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The transcriptional diversity of 25 Drosophila cell lines

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The twin spot generator for differential Drosophila lineage analysis.

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Thermogenesis by THADA.

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Tick hemocytes have a pleiotropic role in microbial infection and arthropod fitness

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Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila

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Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

scientific article published in July 1998

Toward a Systems Understanding of Signaling Pathway Function

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Tumor-Derived Ligands Trigger Tumor Growth and Host Wasting via Differential MEK Activation

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UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents.

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Unconventional ways to travel.

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Understanding cellular signaling and systems biology with precision: A perspective from ultrastructure and organelle studies in the Drosophila midgut

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Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs

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Use of a label-free quantitative platform based on MS/MS average TIC to calculate dynamics of protein complexes in insulin signaling

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Use of a yeast site-specific recombinase to generate embryonic mosaics in Drosophila.

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Use of the CRISPR-Cas9 System in Drosophila Cultured Cells to Introduce Fluorescent Tags into Endogenous Genes

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Using RNAi to catch Drosophila genes in a web of interactions: insights into cancer research

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Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens

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Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster

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Visualizing and manipulating temporal signaling dynamics with fluorescence-based tools

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Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo

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Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila

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Wildtype adult stem cells, unlike tumor cells, are resistant to cellular damages in Drosophila

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Wingless, hedgehog and heparan sulfate proteoglycans

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Xio is a component of the Drosophila sex determination pathway and RNA N6-methyladenosine methyltransferase complex

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Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development.

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Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila melanogaster Cultured Cells.

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Zinc detoxification: a functional genomics and transcriptomics analysis in Drosophila melanogaster cultured cells

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dishevelled and armadillo act in the wingless signalling pathway in Drosophila

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eUnaG: a new ligand-inducible fluorescent reporter to detect drug transporter activity in live cells

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iProteinDB: An Integrative Database of Post-translational Modifications

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intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals

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mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability

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mTORC1-chaperonin CCT signaling regulates mA RNA methylation to suppress autophagy

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miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga

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miR-263a Regulates ENaC to Maintain Osmotic and Intestinal Stem Cell Homeostasis in Drosophila

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neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions

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ovoD Co-selection: A Method for Enriching CRISPR/Cas9-Edited Alleles in Drosophila

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spenito is required for sex determination in Drosophila melanogaster

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wingless refines its own expression domain on the Drosophila wing margin.

scientific article published in November 1996

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