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List of works by Shemin Lu

A comparative genetic analysis between collagen-induced arthritis and pristane-induced arthritis.

scientific article

A comparison of peginterferon α-2a and α-2b for treatment-naive patients with chronic hepatitis C virus: A meta-analysis of randomized trials.

scientific article published on August 2010

A comprehensive meta-analysis of association between genetic variants of GDF5 and osteoarthritis of the knee, hip and hand.

scientific article published on 17 April 2015

A modified method using TRIzol reagent and liquid nitrogen produces high-quality RNA from rat pancreas.

scientific article

A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism.

scientific article published on 11 December 2015

A novel replicated association between FXYD6 gene and schizophrenia

article

Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes

scientific article published on 28 May 2019

Abnormality of epiphyseal plate induced by selenium deficiency diet in two generation DA rats

scientific article published on 25 May 2015

Activation of α1 adrenoceptors in ventrolateral orbital cortex attenuates allodynia induced by spared nerve injury in rats.

scientific article published on 10 June 2016

Age versus clinical virological characteristics in chronic hepatitis B virus infection: a case series study in China

scientific article published in April 2012

Alteration of airway responsiveness mediated by receptors in ovalbumin-induced asthmatic E3 rats.

scientific article

Analysis of correlation between blood biochemical indicators and bone mineral density of post-menopausal women.

scientific article published on 20 May 2010

Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.

scientific article

Arthritis induced in rats with nonimmunogenic adjuvants as models for rheumatoid arthritis.

scientific article

Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts

scientific article published on 27 June 2011

Autoimmune and inflammatory responses in Kashin-Beck disease compared with rheumatoid arthritis and osteoarthritis

article

Autophagy induction contributes to the resistance to methotrexate treatment in rheumatoid arthritis fibroblast-like synovial cells through high mobility group box chromosomal protein 1.

scientific article

Beclin1 overexpression suppresses tumor cell proliferation and survival via an autophagy‑dependent pathway in human synovial sarcoma cells

scientific article published on 25 July 2018

Bioinformatic prediction and functional characterization of human KIAA0100 gene.

scientific article published on 2 November 2016

Black seed oil ameliorates allergic airway inflammation by inhibiting T-cell proliferation in rats.

scientific article published on 27 November 2008

Both common and unique susceptibility genes in different rat strains with pristane-induced arthritis

article

Class II major histocompatibility complex-associated response to type XI collagen regulates the development of chronic arthritis in rats

article

Combination of 2-methoxy-3-phenylsulfonylaminobenzamide and 2-aminobenzothiazole to discover novel anticancer agents

scientific article published on 15 May 2014

Constitutive high expression of protein arginine methyltransferase 1 in asthmatic airway smooth muscle cells is caused by reduced microRNA-19a expression and leads to enhanced remodeling.

scientific article published on 9 January 2017

Construction of Conveniently Screening pLKO.1-TRC Vector Tagged with TurboGFP.

scientific article

Correlation analysis between bone mineral density and serum element contents of postmenopausal women in Xi'an urban area

scientific article

Correlation of AIM2 expression in peripheral blood mononuclear cells from humans with acute and chronic hepatitis B.

scientific article published on 31 January 2013

Design, synthesis and antiproliferative activity evaluation of m-(4-morpholinyl-1,3,5-triazin-2-yl)benzamides in vitro.

scientific article published on 6 March 2015

Different Therapeutic and Bystander Effects by Intranasal Administration of Homologous Type II and Type IX Collagens on the Collagen-Induced Arthritis and Pristane-Induced Arthritis in Rats

scientific article published on 01 January 1999

Different challenge terms determine disease patterns of antigen-induced pulmonary inflammation in E3 rats

scientific article published on 08 February 2011

Direct role of interrod spacing in mediating cell adhesion on Sr-HA nanorod-patterned coatings

scientific article published on 08 March 2014

Discovery of 2-(aminopyrimidin-5-yl)-4-(morpholin-4-yl)-6- substituted triazine as PI3K and BRAF dual inhibitor

article

Discovery of 2-aryl-8-hydroxy (or methoxy)-isoquinolin-1(2H)-ones as novel EGFR inhibitor by scaffold hopping.

scientific article published on 18 September 2013

Discovery of 4-benzoylamino-N-(prop-2-yn-1-yl)benzamides as novel microRNA-21 inhibitors

scientific article published on 14 August 2015

Down-regulated HS6ST2 in osteoarthritis and Kashin-Beck disease inhibits cell viability and influences expression of the genes relevant to aggrecan metabolism of human chondrocytes

scientific article

Down-regulated in OA cartilage, SFMBT2 contributes to NF-κB-mediated ECM degradation

scientific article published on 22 August 2018

Down-regulation of miR-10a-5p in synoviocytes contributes to TBX5-controlled joint inflammation

scientific article

Down-regulation of miR-10a-5p promotes proliferation and restricts apoptosis via targeting T-box transcription factor 5 in inflamed synoviocytes.

scientific article published on 15 March 2018

Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats

article

Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.

scientific article published on 13 June 2018

Enhanced osteoblast functions and bactericidal effect of Ca and Ag dual-ion implanted surface layers on nanograined titanium alloys

scientific article published on 13 June 2014

Enhanced osteoblast functions of narrow interligand spaced Sr-HA nano-fibers/rods grown on microporous titania coatings

scholarly article by Yong Han et al published 2013 in RSC Advances

Evidence for transmission disequilibrium at the DAOA gene locus in a schizophrenia family sample.

scientific article

Extra-articular cartilage affected in collagen-induced, but not pristane-induced, arthritis models

scientific article

Extracellular microRNA-21 and microRNA-26a increase in body fluids from rats with antigen induced pulmonary inflammation and children with recurrent wheezing

scientific article

From selenoprotein to endochondral ossification: a novel mechanism with microRNAs potential in bone related diseases?

scientific article published in November 2011

Further evidence for the association of genetic variants of ZNF804A with schizophrenia and a meta-analysis for genome-wide significance variant rs1344706

article

GPx1 knockdown suppresses chondrogenic differentiation of ATDC5 cells through induction of reductive stress.

scientific article published on 29 December 2016

Genetic analysis of glutamate cysteine ligase modifier (GCLM) gene and schizophrenia in Han Chinese

scientific article published on 12 January 2010

Genetic evidence for the association between the early growth response 3 (EGR3) gene and schizophrenia

scientific article

HDAC3 interacts with sumoylated C/EBPα to negatively regulate the LXRα expression in rat hepatocytes

scientific journal article

High expression of liver histone deacetylase 3 contributes to high-fat-diet-induced metabolic syndrome by suppressing the PPAR-γ and LXR-α-pathways in E3 rats

scientific journal article

Housekeeping gene stability in pristane-induced arthritis and antigen-induced pulmonary inflammation of rats.

scientific article

IL‑22 expression is increased variedly in the initial phase, onset and chronic phase of a pristane‑induced arthritis rat model.

scientific article published on 9 June 2017

Identification and application of anti-inflammatory compounds screening system based on RAW264.7 cells stably expressing NF-κB-dependent SEAP reporter gene

scientific article

Identification of differentially expressed genes related to metabolic syndrome induced with high-fat diet in E3 rats

scientific article

Immunization of Rats with Homologous Type XI Collagen Leads to Chronic and Relapsing Arthritis with Different Genetics and Joint Pathology Than Arthritis Induced with Homologous Type II Collagen

article

Inconsistent susceptibility to autoimmunity in inbred LEW rats is due to genetic crossbreeding involving segregation of the arthritis-regulating gene Ncf1.

scientific article published in May 2004

Increased expression of Th17 cytokines and interleukin-22 correlates with disease activity in pristane-induced arthritis in rats

scientific article published on 28 November 2017

Induction of toll-like receptor 2 positive antigen-presenting cells in spleen of pristane-induced arthritis in rats

scientific article published on 03 July 2011

Infliximab alleviates inflammation and ex vivo airway hyperreactivity in asthmatic E3 rats

scientific article published on 15 June 2011

Interferon plus Chinese herbs are associated with higher sustained virological response than interferon alone in chronic Hepatitis C: a meta-analysis of randomised trials

scientific article published on 15 December 2010

Interpreting the MicroRNA-15/107 family: interaction identification by combining network based and experiment supported approach.

scientific article

Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes

scientific article published on 31 August 2020

Is the EFNB2 locus associated with schizophrenia? Single nucleotide polymorphisms and haplotypes analysis

article

Is the conserved mammalian region of ZNF804A locus associated with schizophrenia? A population-based genetics analysis

article

Maintenance of SOX9 stability and ECM homeostasis by selenium-sensitive PRMT5 in cartilage

scientific article published on 09 March 2019

Mechanical hyperalgesia is attenuated by local administration of octreotide in pristane-induced arthritis in Dark-Agouti rats.

scientific article

Methotrexate affects HMGB1 expression in rheumatoid arthritis, and the downregulation of HMGB1 prevents rheumatoid arthritis progression.

scientific article published on 13 August 2016

Methotrexate ameliorates pristane-induced arthritis by decreasing IFN-γ and IL-17A expressions

scientific article

MiR-223 targeting MAFB suppresses proliferation and migration of nasopharyngeal carcinoma cells

scientific article published on 9 June 2015

MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats.

scientific article published on 14 January 2014

MicroRNA-337 is associated with chondrogenesis through regulating TGFBR2 expression.

scientific article

MicroRNAs of rat articular cartilage at different developmental stages identified by Solexa sequencing.

scientific article

Mitogen-activated protein kinase pathways are involved in the upregulation of calcitonin gene-related peptide of rat trigeminal ganglion after organ culture.

scientific article published on 20 April 2012

Molecular immune pathogenesis and diagnosis of COVID-19

scientific article published on 05 March 2020

NOD2 pathway via RIPK2 and TBK1 is involved in the aberrant catabolism induced by T-2 toxin in chondrocytes.

scientific article

Natural polymorphism of Ym1 regulates pneumonitis through alternative activation of macrophages

scientific article published on 21 October 2020

Nitric Oxide in Both Bronchoalveolar Lavage Fluid and Serum Is Associated With Pathogenesis and Severity of Antigen-Induced Pulmonary Inflammation in Rats

scientific article published on 01 March 2010

Overexpression of Toll-Like Receptor 3 in Spleen is Associated with Experimental Arthritis in Rats

scientific article published on 01 September 2012

PDGF-BB induces PRMT1 expression through ERK1/2 dependent STAT1 activation and regulates remodeling in primary human lung fibroblasts.

scientific article published on 18 January 2016

PRMT1 Modulates Processing of Asthma-Related Primary MicroRNAs (Pri-miRNAs) into Mature miRNAs in Lung Epithelial Cells

scientific article published on 25 November 2020

PRMT1 Upregulated by Epithelial Proinflammatory Cytokines Participates in COX2 Expression in Fibroblasts and Chronic Antigen-Induced Pulmonary Inflammation.

scientific article published on 29 May 2015

Pdcd4 modulates markers of macrophage alternative activation and airway remodeling in antigen-induced pulmonary inflammation

scientific article

Population-based and family-based association studies of ZNF804A locus and schizophrenia

scientific article published on 11 May 2010

Positional identification of Ncf1 as a gene that regulates arthritis severity in rats

scientific journal article

Preparation of monoclonal antibody against human KIAA0100 protein and Northern blot analysis of human KIAA0100 gene

scientific article published on 16 February 2017

Pristane induces autophagy in macrophages, promoting a STAT1-IRF1-TLR3 pathway and arthritis.

scientific article published on 7 December 2016

Pristane primed rat T cells enhance TLR3 expression of fibroblast-like synoviocytes via TNF-α initiated p38 MAPK and NF-κB pathways.

scientific article published on 19 December 2014

Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat

scientific article published on 01 January 2006

Proinflammatory macrophages impair skeletal muscle differentiation in obesity through secretion of tumor necrosis factor-α via sustained activation of p38 mitogen-activated protein kinase

scientific article published on 27 September 2018

Reduced apoptosis correlates with enhanced autophagy in synovial tissues of rheumatoid arthritis

scientific article published on 20 November 2012

Regulation of osteoblast proliferation and differentiation by interrod spacing of Sr-HA nanorods on microporous titania coatings

scientific article published on 21 May 2013

Relationships between endothelial nitric oxide synthase gene polymorphisms and osteoporosis in postmenopausal women

scientific article published on August 2009

Role of grain size in the regulation of osteoblast response to Ti-25Nb-3Mo-3Zr-2Sn alloy.

scientific article published on 15 June 2013

Rosmarinic acid inhibits nicotine-induced C-reactive protein generation by inhibiting NLRP3 inflammasome activation in smooth muscle cells

scientific article published on 26 August 2018

SFMBT2 positively regulates SOX9 and chondrocyte proliferation

scientific article published on 25 September 2018

Selenium effect on selenoprotein transcriptome in chondrocytes

scientific article published on 07 March 2013

Selenium promotes proliferation of chondrogenic cell ATDC5 by increment of intracellular ATP content under serum deprivation.

scientific article published on 29 May 2012

Selenium-sensitive miRNA-181a-5p targeting SBP2 regulates selenoproteins expression in cartilage

scientific article published on 24 September 2018

Selenoprotein O deficiencies suppress chondrogenic differentiation of ATDC5 cells.

scientific article published on 18 July 2016

Signaling network between the dysregulated expression of microRNAs and mRNAs in propofol-induced developmental neurotoxicity in mice

scientific article published in Scientific Reports

Sodium selenite induces apoptosis and inhibits autophagy in human synovial sarcoma cell line SW982 in vitro.

scientific article

Specific regulation of PRMT1 expression by PIAS1 and RKIP in BEAS-2B epithelia cells and HFL-1 fibroblasts in lung inflammation.

scientific article

Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

scientific article published on 25 October 2016

Synthesis and anticancer activity evaluation of a series of [1,2,4]triazolo[1,5-a]pyridinylpyridines in vitro and in vivo.

scientific article

Synthesis and anticancer effects evaluation of 1-alkyl-3-(6-(2-methoxy-3-sulfonylaminopyridin-5-yl)benzo[d]thiazol-2-yl)urea as anticancer agents with low toxicity.

scientific article published on 19 August 2015

Synthesis and antitumor activities evaluation of m-(4-morpholinoquinazolin-2-yl)benzamides in vitro and in vivo.

scientific article published on 17 April 2015

Synthesis and antitumor activity evaluation of PI3K inhibitors containing 3-substituted quinazolin-4(3H)-one moiety

scientific article published on 22 November 2015

Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC-EGFR dual inhibitors.

scientific article

T-2 Toxin Induces Epiphyseal Plate Lesions via Decreased SECISBP2-Mediated Selenoprotein Expression in DA Rats, Exacerbated by Selenium Deficiency

scientific article published on 29 December 2018

T-2 toxin enhances catabolic activity of hypertrophic chondrocytes through ROS-NF-κB-HIF-2α pathway ⬇️

scientific article published on July 16, 2012

TGF-β Upregulated Mitochondria Mass through the SMAD2/3→C/EBPβ→PRMT1 Signal Pathway in Primary Human Lung Fibroblasts

scientific article published on 10 December 2018

TLR3 and TLR7 modulate IgE production in antigen induced pulmonary inflammation via influencing IL-4 expression in immune organs.

scientific article

The elevated expression of Th17-related cytokines and receptors is associated with skin lesion severity in early systemic sclerosis.

scientific article published on 11 December 2014

The major T cell epitope on type II collagen is glycosylated in normal cartilage but modified by arthritis in both rats and humans.

scientific article

The major histocompatibility complex genes are associated with basal pain sensitivity differences between Dark-Agouti and novel congenic DA.1U rats.

scientific article published on 13 May 2010

Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats

scientific journal article

Transcription factor AP1 binds the functional region of the promoter and regulates gene expression of human PPARdelta in LoVo cell.

scientific article published on 6 July 2013

TrxR2 deficiencies promote chondrogenic differentiation and induce apoptosis of chondrocytes through mitochondrial reactive oxygen species.

scientific article published on 20 April 2016

Tumor necrosis factor-α and diabetic retinopathy: Review and meta-analysis

scientific article published on 28 June 2018

Upregulated PKM2 in Macrophages Exacerbates Experimental Arthritis via STAT1 Signaling

scientific article published on 05 June 2020

Upregulated Protein Arginine Methyltransferase 1 by IL-4 Increases Eotaxin-1 Expression in Airway Epithelial Cells and Participates in Antigen-Induced Pulmonary Inflammation in Rats

scientific article published on 02 March 2012

Upregulation of miR-497 induces hepatic insulin resistance in E3 rats with HFD-MetS by targeting insulin receptor.

scientific article

miR-497 Is Implicated in the Process of Chondrogenesis and Inhibits IHH Gene Expression in Human Chondrocytes

scientific article published on 29 August 2018

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