Search filters

List of works by William M Gallagher

A Machine Learning System for Identifying Hypertrophy in Histopathology Images

scholarly article by Ross Foley et al published 2010 in Lecture Notes in Computer Science

A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate

scientific article

A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment

scientific article published on 7 November 2011

A functional genomic screen identifies the deubiquitinase USP11 as a novel transcriptional regulator of ERα in breast cancer

scientific article published on 01 October 2020

A microRNA DNA methylation signature for human cancer metastasis

scholarly article

A novel mechanism of regulation of the anti-metastatic miR-31 by EMSY in breast cancer.

scientific article published on 18 November 2014

A potent nonporphyrin class of photodynamic therapeutic agent: cellular localisation, cytotoxic potential and influence of hypoxia

scientific article

A texture based pattern recognition approach to distinguish melanoma from non-melanoma cells in histopathological tissue microarray sections

scientific article

A trimethoxyphenyl substituted ansa-titanocene: A possible anti-cancer drug

Absolute Quantification of Toxicological Biomarkers via Mass Spectrometry

scientific article

Absolute quantification of toxicological biomarkers by multiple reaction monitoring.

scientific article published in January 2011

Advances in tissue-based imaging: impact on oncology research and clinical practice

scientific article published on 08 June 2020

Altered cytoplasmic-to-nuclear ratio of survivin is a prognostic indicator in breast cancer

scientific article

An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia

scientific article published on 13 December 2010

Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

scientific article published on 3 August 2015

Antibody-based proteomics: fast-tracking molecular diagnostics in oncology.

scientific article

Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer.

scientific article published on 21 April 2017

Application of Artificial Intelligence Techniques to Predict Risk of Recurrence of Breast Cancer: A Systematic Review

scientific article published in 2022

Application of DNA microarray technology in determining breast cancer prognosis and therapeutic response

scientific article

Applications of SELDI-MS technology in oncology

scientific article

Assessment of Significance of Novel Proteins in Breast Cancer Using Tissue Microarray Technology

scientific article published in January 2017

Assessment of candidate biomarkers of drug-induced hepatobiliary injury in preclinical toxicity studies

article

Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach

scientific article

BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer.

scientific article

Bioluminescent imaging: a critical tool in pre-clinical oncology research.

scientific article published on February 2010

Breast cancer proteomics: clinical perspectives.

scientific article published on February 2007

BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome

scientific article published on January 2013

CA IX is an independent prognostic marker in premenopausal breast cancer patients with one to three positive lymph nodes and a putative marker of radiation resistance.

scientific article published in November 2006

CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer

scientific article published on April 2007

Cancer invasion and metastasis: changing views.

scientific article published on February 2008

Characterisation and manipulation of docetaxel resistant prostate cancer cell lines

scientific article

Circulating MicroRNAs in Cancer

article

Clinical Decision Support Systems in Breast Cancer: A Systematic Review

scientific article published on 06 February 2020

Combination of SELDI-TOF-MS and data mining provides early-stage response prediction for rectal tumors undergoing multimodal neoadjuvant therapy

scientific article

Commercialized biomarkers: new horizons in prostate cancer diagnostics

scientific article

Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

scientific article

Contribution of DNA and tissue microarray technology to the identification and validation of biomarkers and personalised medicine in breast cancer.

scientific article published on May 2007

Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

scientific article published in Nature Communications

Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

scientific article published on 5 June 2013

Correlation of the Adhesive Properties of Cells toN-Isopropylacrylamide/N-tert-Butylacrylamide Copolymer Surfaces with Changes in Surface Structure Using Contact Angle Measurements, Molecular Simulations, and Raman Spectroscopy

article

Creation of a digital slide and tissue microarray resource from a multi-institutional predictive toxicology study in the rat: an initial report from the PredTox group

scientific article

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

scientific article published on October 2013

DNA Microarray-Based Gene Expression Profiling in Cancer: Aiding Cancer Diagnosis, Assessing Prognosis and Predicting Response to Therapy

article

DNA microarray-based transcriptomic profiling of an isogenic cell culture model of breast tumour cell invasion.

scientific article

De novo post-diagnosis statin use, breast cancer-specific and overall mortality in women with stage I-III breast cancer

scientific article published on 2 August 2016

Delineating transcriptional networks of prognostic gene signatures refines treatment recommendations for lymph node-negative breast cancer patients

scientific article published on 20 June 2015

Development of a pharmaceutical hepatotoxicity biomarker panel using a discovery to targeted proteomics approach.

scientific article

Diagnostic and Therapeutic Implications of Histone Epigenetic Modulators in Breast Cancer.

scientific article published on 19 February 2016

Differential proteomics incorporating iTRAQ labeling and multi-dimensional separations.

scientific article

Early proteomic analysis may allow noninvasive identification of hepatitis C response to treatment with pegylated interferon α-2b and ribavirin

scientific article

Effect of surface wettability and topography on the adhesion of osteosarcoma cells on plasma-modified polystyrene

scientific article

Effects of HER family-targeting tyrosine kinase inhibitors on antibody-dependent cell-mediated cytotoxicity in HER2-expressing breast cancer

scientific article published on 29 October 2020

Elevated expression and altered processing of fibulin-1 protein in human breast cancer.

scientific article published on March 2003

Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379.

scientific article published on 25 January 2018

Epidemiologic design and analysis for proteomic studies: a primer on -omic technologies

scientific article published on 19 March 2015

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

scientific article published on June 2015

Epigenetics of malignant melanoma.

scientific article published on 23 October 2017

Evaluating liquid biopsies for methylomic profiling of prostate cancer

scientific article published on 31 January 2020

Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer

scientific article

Evaluation of the prognostic significance of MSMB and CRISP3 in prostate cancer using automated image analysis

scientific article

Examination of cell-host-biomaterial interactions via high-throughput technologies: A re-appraisal.

scientific article published on 16 June 2010

Examining the role of Rac1 in tumor angiogenesis and growth: a clinically relevant RNAi-mediated approach

scientific article published on 26 July 2011

Extended delivery of the antimitotic agent colchicine from thermoresponsive N-isopropylacrylamide-based copolymer films to human vascular smooth muscle cells.

scientific article published in November 2003

FKBPL: a marker of good prognosis in breast cancer

scientific article published in May 2015

Fibulins: physiological and disease perspectives.

scientific article

Focus on Cancer Proteomics 12'13

article

Focus on Cancer Proteomics: From Discovery towards Validation ⬇️

scientific article published on 01 July 2010

Formalin-fixed paraffin-embedded clinical tissues show spurious copy number changes in array-CGH profiles.

scientific article

Frequency, impact and a preclinical study of novel gene family mutations in HER2-positive breast cancer

article

Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma

scientific article

Functional interrogation of breast cancer: from models to drugs.

scientific article

Functionalization of emissive conjugated polymer nanoparticles by coprecipitation: consequences for particle photophysics and colloidal properties.

scientific article published on 16 June 2016

Functionalized scaffold-mediated interleukin 10 gene delivery significantly improves survival rates of stem cells in vivo

scientific article

Garbage in, garbage out: a critical evaluation of strategies used for validation of immunohistochemical biomarkers

scientific article

Generation of a new bioluminescent model for visualisation of mammary tumour development in transgenic mice ⬇️

scientific article published on May 30, 2012

Heteroaryl substituted titanocenes as potential anti-cancer drugs

scientific article published on 29 April 2006

Heteroaryl substitutedansa-titanocene anti-cancer drugs derived from fulvenes and titanium dichloride

scholarly article by Franz-Josef K. Rehmann et al published 2005 in Applied Organometallic Chemistry

High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells

scientific article published on 13 October 2020

High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of Interferon Gamma and Interleukin-10 post Myocardial Infarction

scientific article published on 08 August 2009

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.

scientific article

High-throughput proteomics detection of novel splice isoforms in human platelets

scientific article

Human fibulin-4: analysis of its biosynthetic processing and mRNA expression in normal and tumour tissues.

scientific article

Identification and functional validation of therapeutic targets for malignant melanoma.

scientific article published on 27 March 2009

Identification of Apolipoprotein AI as a serum biomarker of chronic kidney disease in liver transplant recipients, using proteomic techniques

scientific article published on 14 August 2008

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

scientific article

Identification of cell surface-specific markers to target human nucleus pulposus cells: expression of carbonic anhydrase XII varies with age and degeneration.

scientific article published in December 2011

Identification of transcription factors associated with castration-resistance: is the serum responsive factor a potential therapeutic target?

scientific article

Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods

scientific article

Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies.

scientific article published on 27 July 2017

Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models

scientific article published on 14 October 2020

In vitro demonstration of the heavy-atom effect for photodynamic therapy.

scientific article published in September 2004

Increased claudin-4 expression is associated with poor prognosis and high tumour grade in breast cancer

scientific article published in May 2009

Inhibition of Serum Response Factor Improves Response to Enzalutamide in Prostate Cancer

scientific article published on 27 November 2020

Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer

scientific article

Interaction of soft condensed materials with living cells: Phenotype/transcriptome correlations for the hydrophobic effect ⬇️

scientific article published on May 13, 2003

Interleukin-6 as a therapeutic target in human ovarian cancer

scientific article

Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models.

scientific article

Investigation of molecular alterations of AKT-3 in triple-negative breast cancer

scientific article

JAM-A expression positively correlates with poor prognosis in breast cancer patients

scientific article

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

scientific article (publication date: June 2011)

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab

scientific article published on 24 May 2018

Low cleaved caspase-7 levels indicate unfavourable outcome across all breast cancers

scientific article published on 01 August 2018

Low pH induces co-ordinate regulation of gene expression in oesophageal cells.

scientific article

Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time

scientific article

Master Transcriptional Regulators in Cancer: Discovery via Reverse Engineering Approaches and Subsequent Validation

scientific article published on 20 April 2017

Mechanism of cell death mediated by a BF2-chelated tetraaryl-azadipyrromethene photodynamic therapeutic: dissection of the apoptotic pathway in vitro and in vivo

scientific article published on 26 May 2011

MetSizeR: selecting the optimal sample size for metabolomic studies using an analysis based approach

scientific article

Metallothionein 1E is methylated in malignant melanoma and increases sensitivity to cisplatin-induced apoptosis.

scientific article published on October 2010

Methoxy-phenyl substituted ansa-titanocenes as potential anti-cancer drugs derived from fulvenes and titanium dichloride

scientific article

Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells.

scientific article

Molecular basis of cell–biomaterial interaction: Insights gained from transcriptomic and proteomic studies

article

Multi-Gene Prognostic Signatures and Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy in ER-positive, HER2-negative Breast Cancer Patients

scientific article published on 01 May 2020

Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies

scientific article published on 15 June 2005

Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007.

scientific article

Mutant p53: a novel target for the treatment of patients with triple-negative breast cancer?

scientific article published on 12 September 2016

Novel "plum pudding" gels as potential drug-eluting stent coatings: controlled release of fluvastatin

scientific article published in December 2006

Novel Method to Prepare Morphologically Rich Polymeric Surfaces for Biomedical Applications via Phase Separation and Arrest of Microgel Particles

article

Novel titanocene anti-cancer drugs derived from fulvenes and titanium dichloride

scholarly article by Matthias Tacke et al published July 2004 in Journal of Organometallic Chemistry

Oligonucleotide microarray analysis of gene expression in neuroblastoma displaying loss of chromosome 11q.

scientific article published on 16 April 2004

Omic profiling for drug safety assessment: current trends and public–private partnerships

article

OvMark: a user-friendly system for the identification of prognostic biomarkers in publically available ovarian cancer gene expression datasets.

scientific article

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

scientific article

PKCzeta regulates cell polarisation and proliferation restriction during mammary acinus formation.

scientific article published on October 2010

Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer

scientific article

Poly(N-isopropylacrylamide) co-polymer films as potential vehicles for delivery of an antimitotic agent to vascular smooth muscle cells

scientific article published in March 2003

Poly(N-isopropylacrylamide) copolymer films as vehicles for the sustained delivery of proteins to vascular endothelial cells

scientific article published on 01 January 2005

Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer.

scientific article published on 14 October 2016

Prioritization of candidate protein biomarkers from an in vitro model system of breast tumor progression toward clinical verification

scientific article

Prognostic ability of a panel of immunohistochemistry markers - retailoring of an 'old solution'.

scientific article published on 25 February 2008

Prognostic and predictive biomarkers in melanoma: an update

scientific article

Proteomic analysis of factors released from p21-overexpressing tumour cells

scientific article published on July 2006

Proteomic portrait of human breast cancer progression identifies novel prognostic markers

scientific article

RE: RNA Disruption Assay as a Biomarker of Pathological Complete Response in Neoadjuvant Trastuzumab-Treated Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer

scientific article published on 4 July 2016

Recent advances in molecular imaging biomarkers in cancer: application of bench to bedside technologies.

scientific article published on 24 December 2009

Relationship between serum response factor and androgen receptor in prostate cancer

scientific article published on 7 August 2015

Role of serum response factor expression in prostate cancer biochemical recurrence

scientific article published on 2 April 2018

SATB2 in Combination With Cytokeratin 20 Identifies Over 95% of all Colorectal Carcinomas

article

SOX10 expression in superficial spreading and nodular malignant melanomas

scientific article published on December 2010

Selected highlights of the Third Annual Biomarkers Congress: from discovery to validation in the drug development arena.

scientific article published on September 2008

Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma

scientific article

Sequence tagging reveals unexpected modifications in toxicoproteomics

scientific article published on 7 January 2011

Serum proteomic profiling reveals that pretreatment complement protein levels are predictive of esophageal cancer patient response to neoadjuvant chemoradiation.

scientific article

Standardization of models and methods used to assess nanoparticles in cardiovascular applications

scientific article published on 11 February 2011

Structural basis of p21H-ras molecular switch inhibition by a neutralizing antibody

scientific article published on 01 February 1996

Supramolecular photonic therapeutic agents.

scientific article published on November 2005

Surface-induced cell signaling events control actin rearrangements and motility.

scientific article published in May 2010

Surface-induced changes in protein adsorption and implications for cellular phenotypic responses to surface interaction

scientific article published on 7 February 2006

Survivin: a promising tumor biomarker

scientific article published on February 2007

Synergistic interaction between trastuzumab and EGFR/HER-2 tyrosine kinase inhibitors in HER-2 positive breast cancer cells

scientific article published on 16 March 2010

Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

scientific article

TGF-β1-induced thrombospondin-1 expression through the p38 MAPK pathway is abolished by fluvastatin in human coronary artery smooth muscle cells

scientific article published on 19 April 2006

Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses

scientific article published on 5 December 2012

The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype

scientific article published on 05 June 2020

The Emerging Role of Non-traditional Ubiquitination in Oncogenic Pathways.

scientific article published on February 2017

The Molecular Effects of a High Fat Diet on Endometrial Tumour Biology

scientific article published on 10 September 2020

The Role of Exosomes in Breast Cancer

scientific article published on 14 October 2015

The VEGF/Rho GTPase signalling pathway: a promising target for anti-angiogenic/anti-invasion therapy.

scientific article published on 22 January 2011

The analysis of serum response factor expression in bone and soft tissue prostate cancer metastases.

scientific article

The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate

scientific article published on 21 January 2013

The chain length of biologically produced (R)-3-hydroxyalkanoic acid affects biological activity and structure of anti-cancer peptides.

scientific article

The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ERα, and is an independent prognostic factor in node-negative breast cancer.

scientific article

The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microarrays on line

scientific article published on 17 May 2006

The emerging role of FK506-binding proteins as cancer biomarkers: a focus on FKBPL.

scientific article published on April 2011

The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells

scientific article

The impact of ERBB-family germline single nucleotide polymorphisms on survival response to adjuvant trastuzumab treatment in HER2-positive breast cancer

scientific article published on 20 October 2016

The influence of size and charge of chitosan/polyglutamic acid hollow spheres on cellular internalization, viability and blood compatibility

scientific article published on 10 August 2010

The transcription factor Sox11 is a prognostic factor for improved recurrence-free survival in epithelial ovarian cancer

scientific article published on 9 March 2009

The tumour suppressor SOX11 is associated with improved survival among high grade epithelial ovarian cancers and is regulated by reversible promoter methylation

scientific article

Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer

scientific article published on 28 April 2017

Tissue Microarrays and Digital Image Analysis ⬇️

scientific article published on January 1, 2011

Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis.

scientific article

Tumor profiling using protein biomarker panels in malignant melanoma: application of tissue microarrays and beyond.

scientific article published on August 2012

Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen ⬇️

scientific article

Tumour islet Foxp3+ T-cell infiltration predicts poor outcome in nonsmall cell lung cancer.

scientific article published on 5 November 2015

Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer

scientific article

Understanding and Attitudes toward Cancer Clinical Trials among Patients with a Cancer Diagnosis: National Study through Cancer Trials Ireland

scientific article published on 16 July 2020

Use of SELDI MS to discover and identify potential biomarkers of toxicity in InnoMed PredTox: a multi-site, multi-compound study

scientific article

Use of proteomics for the discovery of early markers of drug toxicity

article

Use of proteomics for the discovery of early markers of drug toxicity.

scientific article

Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer

scientific article

Validation of the OncoMasTR Risk Score in Estrogen Receptor-Positive/HER2-Negative Patients: A TransATAC study

scientific article published on 22 October 2019

Vascular-targeted photodynamic therapy with BF2-chelated Tetraaryl-Azadipyrromethene agents: a multi-modality molecular imaging approach to therapeutic assessment.

scientific article

Vitamin D receptor as a target for breast cancer therapy

scientific article published on 17 February 2017

hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents ⬇️

scientific article published on July 3, 1997

miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity.

scientific article published on 24 September 2015

miR-187 is an independent prognostic factor in breast cancer and confers increased invasive potential in vitro

scientific article

miRNA dysregulation in breast cancer.

scientific article

microRNAs: a new class of breast cancer biomarkers.

scientific article published on April 2014

p53 as a target for the treatment of cancer.

scientific article published on December 2014

Paulina is supported by:

About Paulina

Help