List of works - Burton F Dickey

A better crystal ball to predict lung-cancer survival?

scientific article published on 01 October 2006

A common MUC5B promoter polymorphism and pulmonary fibrosis.

scientific article

A3 adenosine receptor signaling contributes to airway mucin secretion after allergen challenge

scientific article published on 8 June 2006

Activation of lung toll-like receptors does not exacerbate sickness responses to lipopolysaccharide in mice

scientific article

Airway Mucin Secretion

scientific article published on 01 November 2018

Airway mucus function and dysfunction

scientific article

Airway mucus: From production to secretion.

scientific article

Allergic lung inflammation alters neither susceptibility to Streptococcus pneumoniae infection nor inducibility of innate resistance in mice.

scientific article published on 27 July 2009

Assessment of intracellular mucin content in vivo

scientific article published on January 2012

Augmented lung inflammation protects against influenza A pneumonia.

scientific article

Azithromycin may increase hematologic relapse rates in matched unrelated donor hematopoietic cell transplant recipients who receive anti-thymocyte globulin, but not in most other recipients

scientific article published on 02 October 2020

Baseline Goblet Cell Mucin Secretion in the Airways Exceeds Stimulated Secretion over Extended Time Periods, and Is Sensitive to Shear Stress and Intracellular Mucin Stores

scientific article published on 29 May 2015

Beta-agonist intrinsic efficacy: measurement and clinical significance

scientific article

Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model

scientific article

COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation

scientific article published on 31 August 2018

Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements

scientific article

Chair's Summary: Secreted Mucins in Lung Diseases

scientific article published on 01 November 2018

Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model

scientific article

Clinical implications of the intrinsic efficacy of beta-adrenoceptor drugs in asthma: full, partial and inverse agonism

scientific article

Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir

scientific article

Complementary anti-inflammatory effects of a β-blocker and a corticosteroid in an asthma model

scientific article published on 02 October 2011

Cre-mediated recombination in mouse Clara cells

scientific article

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice

scientific article published on 30 September 2009

Dawn of a New Era in the Diagnosis and Treatment of Airway Mucus Dysfunction

scientific article published on 01 January 2019

Deletion of the gene encoding calcitonin and calcitonin gene-related peptide α does not affect the outcome of severe infection in mice

scientific article published on July 2013

Different Munc18 proteins mediate baseline and stimulated airway mucin secretion

scientific article published on 21 March 2019

Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells

scientific article

E-Cigarettes: Mucus Measurements Make Marks

scientific article published on 01 February 2018

Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation

scientific article published on 12 January 2012

Exoskeletons and exhalation

scientific article published on 01 November 2007

Expression and transcriptional regulation of Munc18 isoforms in mast cells

scientific article

Feasibility and Reliability of Home-based Spirometry Telemonitoring in Allogeneic Hematopoietic Cell Transplant Recipients

scientific article published on 02 July 2020

Gene therapy of mucus hypersecretion in experimental asthma

scientific article

Growth factor independence-1 is expressed in primary human neuroendocrine lung carcinomas and mediates the differentiation of murine pulmonary neuroendocrine cells.

scientific article

Haemophilus influenzae lysate induces aspects of the chronic obstructive pulmonary disease phenotype

scientific article published on 20 December 2007

Helicobacter pylori bacteremia with sepsis syndrome

scientific article

Host lung gene expression patterns predict infectious etiology in a mouse model of pneumonia

scientific article

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites

scientific article published on 03 October 2019

In vivo demonstration and quantification of intracellular Bacillus anthracis in lung epithelial cells

scientific article published on 14 July 2008

Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections.

scientific article

Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice

scientific article published on 22 January 2020

Inducible innate resistance of lung epithelium to infection

scientific article published on January 2010

Infectious respiratory disease in non-HIV immunocompromised patients.

scientific article published on December 2014

Inflammation-induced upregulation of P2X expression augments mucin secretion in airway epithelia

scientific article published on 25 October 2018

Inflammatory gene polymorphisms influence risk of postoperative morbidity after lung resection

scientific article published on 01 May 2005

Inhaled innate immune ligands to prevent pneumonia

scientific article

Inhaled therapeutics for prevention and treatment of pneumonia

scientific article published in July 2009

Interleukin 6, but not T helper 2 cytokines, promotes lung carcinogenesis.

scientific article

Measuring Airway Mucin 2 in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization

scientific article published in November 2016

Muc5ac: a critical component mediating the rejection of enteric nematodes ⬇️

scientific article

Muc5b is required for airway defence

scientific journal article

Mucin is produced by clara cells in the proximal airways of antigen-challenged mice

scientific article

Mucus hypersecretion in asthma: causes and effects

scientific article published on January 2009

Munc13 proteins control regulated exocytosis in mast cells

scientific article published on 15 November 2017

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways

scientific article published on 7 February 2008

Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle regulated exocytosis in mast cells

scientific article published on 29 March 2018

Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells

scientific journal article

MyD88 controls airway epithelial Muc5ac expression during TLR activation conditions from agricultural organic dust exposure

journal article published in 2019

Non-infectious respiratory disease in non-HIV immunocompromised patients.

scientific article published on December 2014

Nontypeable Haemophilus influenzae in chronic obstructive pulmonary disease and lung cancer.

scientific article

Performance of a standardized bronchoalveolar lavage protocol in a comprehensive cancer center: a prospective 2-year study.

scientific article

Pleuropericarditis, obliterative bronchiolitis and lymphocytic interstitial pneumonitis after allogeneic haematopoietic stem cell transplantation

scientific article

Pneumonia during remission induction chemotherapy in patients with acute leukemia

scientific article

Progression of the Radiologic Severity Index predicts mortality in patients with parainfluenza virus-associated lower respiratory infections.

scientific article published on 17 May 2018

Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase

scientific article published on 09 December 2013

Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model

scientific article published on 16 October 2008

Recombinant interferon gamma1b immune enhancement in 20 patients with hematologic malignancies and systemic opportunistic infections treated with donor granulocyte transfusions.

scientific article

Refinement of estimates of mortality risk using the Radiologic Severity Index in hematologic malignancy patients with respiratory syncytial virus infection

scientific article published on 28 May 2019

Regulated airway goblet cell mucin secretion.

scientific article published on January 2008

Regulated mucin secretion from airway epithelial cells

scientific article published on 18 September 2013

SNAP23 is selectively expressed in airway secretory cells and mediates baseline and stimulated mucin secretion

scientific article

Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands

scientific article published on 06 February 2014

Salmeterol stimulation dissociates beta2-adrenergic receptor phosphorylation and internalization

scientific article published on 15 September 2006

Small airway mucous metaplasia and inflammation in chronic obstructive pulmonary disease

scientific article published in December 2008

Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi

scientific article

Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice

scientific article published on 3 April 2008

Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum.

scientific article published on 10 February 2009

Synaptotagmin-2 controls regulated exocytosis but not other secretory responses of mast cells

scientific article published on 27 May 2009

Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses

scientific article

Synergistic TLR2/6 and TLR9 activation protects mice against lethal influenza pneumonia

scientific article (publication date: 2012)

Synergistic interactions of TLR2/6 and TLR9 induce a high level of resistance to lung infection in mice.

scientific article published on 11 April 2011

The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death.

scientific article published on November 2008

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity

scientific article

The role of intrinsic efficacy in determining response to a beta2-agonist in acute severe asthma

scientific article published on 17 October 2006

The safety and effects of the beta-blocker, nadolol, in mild asthma: an open-label pilot study

scientific article

Toll-like receptor-2/6 and Toll-like receptor-9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs.

scientific article published on June 2013

Understanding Interstitial Lung Disease: It's in the Mucus

scientific article published in July 2017

What it takes for a cough to expel mucus from the airway

scientific article published on 20 November 2018

beta-Adrenoceptor inverse agonists in asthma

scientific article published on June 2010

β2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model

scientific article published on 29 November 2012

β2-Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility

scientific article

List of works by Burton F Dickey

A better crystal ball to predict lung-cancer survival?

A common MUC5B promoter polymorphism and pulmonary fibrosis.

A3 adenosine receptor signaling contributes to airway mucin secretion after allergen challenge

Activation of lung toll-like receptors does not exacerbate sickness responses to lipopolysaccharide in mice

Airway Mucin Secretion

Airway mucus function and dysfunction

Airway mucus: From production to secretion.

Allergic lung inflammation alters neither susceptibility to Streptococcus pneumoniae infection nor inducibility of innate resistance in mice.

Assessment of intracellular mucin content in vivo

Augmented lung inflammation protects against influenza A pneumonia.

Azithromycin may increase hematologic relapse rates in matched unrelated donor hematopoietic cell transplant recipients who receive anti-thymocyte globulin, but not in most other recipients

Baseline Goblet Cell Mucin Secretion in the Airways Exceeds Stimulated Secretion over Extended Time Periods, and Is Sensitive to Shear Stress and Intracellular Mucin Stores

Beta-agonist intrinsic efficacy: measurement and clinical significance

Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model

COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation

Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements

Chair's Summary: Secreted Mucins in Lung Diseases

Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model

Clinical implications of the intrinsic efficacy of beta-adrenoceptor drugs in asthma: full, partial and inverse agonism

Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir

Complementary anti-inflammatory effects of a β-blocker and a corticosteroid in an asthma model

Cre-mediated recombination in mouse Clara cells

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice

Dawn of a New Era in the Diagnosis and Treatment of Airway Mucus Dysfunction

Deletion of the gene encoding calcitonin and calcitonin gene-related peptide α does not affect the outcome of severe infection in mice

Different Munc18 proteins mediate baseline and stimulated airway mucin secretion

Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells

E-Cigarettes: Mucus Measurements Make Marks

Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation

Exoskeletons and exhalation

Expression and transcriptional regulation of Munc18 isoforms in mast cells

Feasibility and Reliability of Home-based Spirometry Telemonitoring in Allogeneic Hematopoietic Cell Transplant Recipients

Gene therapy of mucus hypersecretion in experimental asthma

Growth factor independence-1 is expressed in primary human neuroendocrine lung carcinomas and mediates the differentiation of murine pulmonary neuroendocrine cells.

Haemophilus influenzae lysate induces aspects of the chronic obstructive pulmonary disease phenotype

Helicobacter pylori bacteremia with sepsis syndrome

Host lung gene expression patterns predict infectious etiology in a mouse model of pneumonia

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites

In vivo demonstration and quantification of intracellular Bacillus anthracis in lung epithelial cells

Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections.

Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice

Inducible innate resistance of lung epithelium to infection

Infectious respiratory disease in non-HIV immunocompromised patients.

Inflammation-induced upregulation of P2X expression augments mucin secretion in airway epithelia

Inflammatory gene polymorphisms influence risk of postoperative morbidity after lung resection

Inhaled innate immune ligands to prevent pneumonia

Inhaled therapeutics for prevention and treatment of pneumonia

Interleukin 6, but not T helper 2 cytokines, promotes lung carcinogenesis.

Measuring Airway Mucin 2 in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization

Muc5ac: a critical component mediating the rejection of enteric nematodes ⬇️

Muc5b is required for airway defence

Mucin is produced by clara cells in the proximal airways of antigen-challenged mice

Mucus hypersecretion in asthma: causes and effects

Munc13 proteins control regulated exocytosis in mast cells

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways

Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle regulated exocytosis in mast cells

Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells

MyD88 controls airway epithelial Muc5ac expression during TLR activation conditions from agricultural organic dust exposure

Non-infectious respiratory disease in non-HIV immunocompromised patients.

Nontypeable Haemophilus influenzae in chronic obstructive pulmonary disease and lung cancer.

Performance of a standardized bronchoalveolar lavage protocol in a comprehensive cancer center: a prospective 2-year study.

Pleuropericarditis, obliterative bronchiolitis and lymphocytic interstitial pneumonitis after allogeneic haematopoietic stem cell transplantation

Pneumonia during remission induction chemotherapy in patients with acute leukemia

Progression of the Radiologic Severity Index predicts mortality in patients with parainfluenza virus-associated lower respiratory infections.

Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase

Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model

Recombinant interferon gamma1b immune enhancement in 20 patients with hematologic malignancies and systemic opportunistic infections treated with donor granulocyte transfusions.

Refinement of estimates of mortality risk using the Radiologic Severity Index in hematologic malignancy patients with respiratory syncytial virus infection

Regulated airway goblet cell mucin secretion.

Regulated mucin secretion from airway epithelial cells

SNAP23 is selectively expressed in airway secretory cells and mediates baseline and stimulated mucin secretion

Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands

Salmeterol stimulation dissociates beta2-adrenergic receptor phosphorylation and internalization

Small airway mucous metaplasia and inflammation in chronic obstructive pulmonary disease

Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi

Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice

Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum.

Synaptotagmin-2 controls regulated exocytosis but not other secretory responses of mast cells

Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses