List of works - Christopher D. Bayliss

A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus.

scientific article published in January 1991

Assessment of fHbp Expression Level by Reverse Transcriptase Quantitative PCR and Promoter Sequence Analysis

scientific article published on 01 January 2019

Broad conditions favor the evolution of phase-variable loci.

scientific article published on 8 January 2013

Carriage of meningococci by university students, United Kingdom.

scientific article published on September 2011

Clustered intergenic region sequences as predictors of factor H Binding Protein expression patterns and for assessing Neisseria meningitidis strain coverage by meningococcal vaccines.

scientific article

Co-administration of the Campylobacter jejuni N-glycan based vaccine with probiotics improves vaccine performance in broiler chickens

scientific article published on 22 September 2017

Construction of Opa-positive and Opa-negative strains of Neisseria meningitidis to evaluate a novel meningococcal vaccine

scientific article

Determinants of phase variation rate and the fitness implications of differing rates for bacterial pathogens and commensals.

scientific article

Determination of Repeat Number and Expression States of Phase-Variable Loci Through Next Generation Sequencing and Bioinformatic Analysis

scientific article published on 01 January 2019

Distribution and diversity of the haemoglobin-haptoglobin iron-acquisition systems in pathogenic and non-pathogenic Neisseria.

scientific article published on 27 June 2013

Erratum for Aidley et al., "Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations".

scientific article

Evolution of simple sequence repeat-mediated phase variation in bacterial genomes

scientific article published in September 2012

Gastro-duodenal disease in Africa: Literature review and clinical data from Accra, Ghana.

scientific article published on 01 July 2019

Genomic Analysis of Serogroup Y Neisseria meningitidis Isolates Reveals Extensive Similarities Between Carriage-Associated and Disease-Associated Organisms

scientific article published on 7 January 2016

Genomic and global approaches to unravelling how hypermutable sequences influence bacterial pathogenesis.

scientific article

Helicobacter pylori cagA and vacA genes in dyspeptic Ghanaian patients

scientific article

High Throughput Method for Analysis of Repeat Number for 28 Phase Variable Loci of Campylobacter jejuni Strain NCTC11168.

scientific article

High allelic diversity in the methyltransferase gene of a phase variable type III restriction-modification system has implications for the fitness of Haemophilus influenzae

scientific article published on 16 August 2006

Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage.

scientific article published on 25 September 2010

Identification of the functional initiation codons of a phase-variable gene of Haemophilus influenzae, lic2A, with the potential for differential expression

scientific article published on 10 November 2006

Influence of the combination and phase variation status of the haemoglobin receptors HmbR and HpuAB on meningococcal virulence.

scientific article

Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia.

scientific article published on 16 April 2018

Investigation into the Antigenic Properties and Contributions to Growth in Blood of the Meningococcal Haemoglobin Receptors, HpuAB and HmbR.

scientific article published on 24 July 2015

Limited impact of adolescent meningococcal ACWY vaccination on group W carriage in university students.

scientific article published on 15 November 2017

Localized Hypermutation is the Major Driver of Meningococcal Genetic Variability during Persistent Asymptomatic Carriage

scientific article published on 24 March 2020

Men B: lack of coverage or vaccine failure?

scientific article published on 01 February 2016

Microbial DNA metabolism, genome dynamics and human disease

article

Mutation and Selection in Bacteria: Modelling and Calibration

scientific article published on 14 November 2018

Mutations in Haemophilus influenzae mismatch repair genes increase mutation rates of dinucleotide repeat tracts but not dinucleotide repeat-driven pilin phase variation rates

scientific article published on May 2004

Mutations in polI but not mutSLH destabilize Haemophilus influenzae tetranucleotide repeats

scientific article published on March 2002

Neisseria meningitidis escape from the bactericidal activity of a monoclonal antibody is mediated by phase variation of lgtG and enhanced by a mutator phenotype

scientific article published on 11 August 2008

Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations.

scientific article published on 4 April 2017

Persistence, replacement, and rapid clonal expansion of meningococcal carriage isolates in a 2008 university student cohort.

scientific article published on December 2010

Phage exposure causes dynamic shifts in the expression states of specific phase-variable genes of Campylobacter jejuni.

scientific article published on 8 June 2017

Phage-Resistant Phase-Variant Sub-populations Mediate Herd Immunity Against Bacteriophage Invasion of Bacterial Meta-Populations ⬇️

scientific article published on 05 July 2019

Phase Variation of NadA in Invasive Neisseria meningitidis Isolates Impacts on Coverage Estimates for 4C-MenB, a MenB Vaccine ⬇️

article

Phase Variation of PorA, a Major Outer Membrane Protein, Mediates Escape of Bactericidal Antibodies by Neisseria meningitidis ⬇️

scientific article published on February 12, 2013

Phase variable genes of Campylobacter jejuni exhibit high mutation rates and specific mutational patterns but mutability is not the major determinant of population structure during host colonization

scientific article published on 20 March 2012

Phase variation mediates reductions in expression of surface proteins during persistent meningococcal carriage

scientific article

Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168

scientific article

Phasome analysis of pathogenic and commensal Neisseria species expands the known repertoire of phase variable genes, and highlights common adaptive strategies.

scientific article published on 15 May 2018

PhasomeIt: an 'omics' approach to cataloguing the potential breadth of phase variation in the genus Campylobacter

article

Potentiation of Phase Variation in Multiple Outer-Membrane Proteins During Spread of the Hyperinvasive Neisseria meningitidis Serogroup W ST-11 Lineage

scientific article published on 01 August 2019

Prevalence and phase variable expression status of two autotransporters, NalP and MspA, in carriage and disease isolates of Neisseria meningitidis.

scientific article

Random sorting of Campylobacter jejuni phase variants due to a narrow bottleneck during colonization of broiler chickens

scientific article published on 01 June 2018

RecJ, ExoI and RecG are required for genome maintenance but not for generation of genetic diversity by repeat-mediated phase variation in Haemophilus influenzae.

scientific article published on 23 December 2007

Recombination of the Phase-Variable spnIII Locus Is Independent of All Known Pneumococcal Site-Specific Recombinases

scientific article published on 10 July 2019

Rise in Group W Meningococcal Carriage in University Students, United Kingdom.

scientific article published on June 2017

Selective and non-selective bottlenecks as drivers of the evolution of hypermutable bacterial loci

scientific article published on 01 March 2020

Simple sequence repeats (microsatellites): mutational mechanisms and contributions to bacterial pathogenesis. A meeting review.

scientific article published on January 2004

Temperature-sensitive mutants in the vaccinia virus A18R gene increase double-stranded RNA synthesis as a result of aberrant viral transcription

scientific article published in May 1993

The distribution and 'in vivo' phase variation status of haemoglobin receptors in invasive meningococcal serogroup B disease: genotypic and phenotypic analysis

scientific article

The generation of diversity by Haemophilus influenzae: response.

scientific article published in October 2000

The length of a tetranucleotide repeat tract in Haemophilus influenzae determines the phase variation rate of a gene with homology to type III DNA methyltransferases.

scientific article published on January 2000

The vaccinia virus A18R gene product is a DNA-dependent ATPase

scientific article published on January 1995

University vaccine campaign increases meningococcal ACWY vaccine coverage.

scientific article published on 12 January 2017

Vaccinia virion protein VP8, the 25 kDa product of the L4R gene, binds single-stranded DNA and RNA with similar affinity.

scientific article

Variation in the genomic locations and sequence conservation of STAR elements among staphylococcal species provides insight into DNA repeat evolution.

scientific article

List of works by Christopher D. Bayliss

A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus.

Assessment of fHbp Expression Level by Reverse Transcriptase Quantitative PCR and Promoter Sequence Analysis

Broad conditions favor the evolution of phase-variable loci.

Carriage of meningococci by university students, United Kingdom.

Clustered intergenic region sequences as predictors of factor H Binding Protein expression patterns and for assessing Neisseria meningitidis strain coverage by meningococcal vaccines.

Co-administration of the Campylobacter jejuni N-glycan based vaccine with probiotics improves vaccine performance in broiler chickens

Construction of Opa-positive and Opa-negative strains of Neisseria meningitidis to evaluate a novel meningococcal vaccine

Determinants of phase variation rate and the fitness implications of differing rates for bacterial pathogens and commensals.

Determination of Repeat Number and Expression States of Phase-Variable Loci Through Next Generation Sequencing and Bioinformatic Analysis

Distribution and diversity of the haemoglobin-haptoglobin iron-acquisition systems in pathogenic and non-pathogenic Neisseria.

Erratum for Aidley et al., "Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations".

Evolution of simple sequence repeat-mediated phase variation in bacterial genomes

Gastro-duodenal disease in Africa: Literature review and clinical data from Accra, Ghana.

Genomic Analysis of Serogroup Y Neisseria meningitidis Isolates Reveals Extensive Similarities Between Carriage-Associated and Disease-Associated Organisms

Genomic and global approaches to unravelling how hypermutable sequences influence bacterial pathogenesis.

Helicobacter pylori cagA and vacA genes in dyspeptic Ghanaian patients

High Throughput Method for Analysis of Repeat Number for 28 Phase Variable Loci of Campylobacter jejuni Strain NCTC11168.

High allelic diversity in the methyltransferase gene of a phase variable type III restriction-modification system has implications for the fitness of Haemophilus influenzae

Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage.

Identification of the functional initiation codons of a phase-variable gene of Haemophilus influenzae, lic2A, with the potential for differential expression

Influence of the combination and phase variation status of the haemoglobin receptors HmbR and HpuAB on meningococcal virulence.

Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia.

Investigation into the Antigenic Properties and Contributions to Growth in Blood of the Meningococcal Haemoglobin Receptors, HpuAB and HmbR.

Limited impact of adolescent meningococcal ACWY vaccination on group W carriage in university students.

Localized Hypermutation is the Major Driver of Meningococcal Genetic Variability during Persistent Asymptomatic Carriage

Men B: lack of coverage or vaccine failure?

Microbial DNA metabolism, genome dynamics and human disease

Mutation and Selection in Bacteria: Modelling and Calibration

Mutations in Haemophilus influenzae mismatch repair genes increase mutation rates of dinucleotide repeat tracts but not dinucleotide repeat-driven pilin phase variation rates

Mutations in polI but not mutSLH destabilize Haemophilus influenzae tetranucleotide repeats

Neisseria meningitidis escape from the bactericidal activity of a monoclonal antibody is mediated by phase variation of lgtG and enhanced by a mutator phenotype

Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations.

Persistence, replacement, and rapid clonal expansion of meningococcal carriage isolates in a 2008 university student cohort.

Phage exposure causes dynamic shifts in the expression states of specific phase-variable genes of Campylobacter jejuni.

Phage-Resistant Phase-Variant Sub-populations Mediate Herd Immunity Against Bacteriophage Invasion of Bacterial Meta-Populations ⬇️

Phase Variation of NadA in Invasive Neisseria meningitidis Isolates Impacts on Coverage Estimates for 4C-MenB, a MenB Vaccine ⬇️

Phase Variation of PorA, a Major Outer Membrane Protein, Mediates Escape of Bactericidal Antibodies by Neisseria meningitidis ⬇️

Phase variable genes of Campylobacter jejuni exhibit high mutation rates and specific mutational patterns but mutability is not the major determinant of population structure during host colonization

Phase variation mediates reductions in expression of surface proteins during persistent meningococcal carriage

Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168

Phasome analysis of pathogenic and commensal Neisseria species expands the known repertoire of phase variable genes, and highlights common adaptive strategies.

PhasomeIt: an 'omics' approach to cataloguing the potential breadth of phase variation in the genus Campylobacter

Potentiation of Phase Variation in Multiple Outer-Membrane Proteins During Spread of the Hyperinvasive Neisseria meningitidis Serogroup W ST-11 Lineage

Prevalence and phase variable expression status of two autotransporters, NalP and MspA, in carriage and disease isolates of Neisseria meningitidis.

Random sorting of Campylobacter jejuni phase variants due to a narrow bottleneck during colonization of broiler chickens

RecJ, ExoI and RecG are required for genome maintenance but not for generation of genetic diversity by repeat-mediated phase variation in Haemophilus influenzae.

Recombination of the Phase-Variable spnIII Locus Is Independent of All Known Pneumococcal Site-Specific Recombinases

Rise in Group W Meningococcal Carriage in University Students, United Kingdom.

Selective and non-selective bottlenecks as drivers of the evolution of hypermutable bacterial loci

Simple sequence repeats (microsatellites): mutational mechanisms and contributions to bacterial pathogenesis. A meeting review.

Temperature-sensitive mutants in the vaccinia virus A18R gene increase double-stranded RNA synthesis as a result of aberrant viral transcription

The distribution and 'in vivo' phase variation status of haemoglobin receptors in invasive meningococcal serogroup B disease: genotypic and phenotypic analysis

The generation of diversity by Haemophilus influenzae: response.

The length of a tetranucleotide repeat tract in Haemophilus influenzae determines the phase variation rate of a gene with homology to type III DNA methyltransferases.

The vaccinia virus A18R gene product is a DNA-dependent ATPase

University vaccine campaign increases meningococcal ACWY vaccine coverage.

Vaccinia virion protein VP8, the 25 kDa product of the L4R gene, binds single-stranded DNA and RNA with similar affinity.

Variation in the genomic locations and sequence conservation of STAR elements among staphylococcal species provides insight into DNA repeat evolution.