List of works by Clive Wasserfall

A case of unfulfilled expectations. Cytokines in idiopathic minimal lesion nephrotic syndrome.

scientific article

A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.

scientific article

Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset

scientific article published on 01 March 2003

Adeno-associated viral vector-mediated interleukin-10 prolongs allograft survival in a rat kidney transplantation model

scientific article published in May 2007

Adeno-associated virus transduction of islets with interleukin-4 results in impaired metabolic function in syngeneic marginal islet mass transplantation.

scientific article published in October 2002

Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

scientific article published in March 2003

Adiponectin and leptin concentrations may aid in discriminating disease forms in children and adolescents with type 1 and type 2 diabetes

scientific article published on 01 August 2004

Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model

scientific article published on 24 February 2011

Alpha-1 antitrypsin treatment of spontaneously diabetic nonobese diabetic mice receiving islet allografts

scientific article published in March 2008

Alpha1-antitrypsin gene therapy modulates cellular immunity and efficiently prevents type 1 diabetes in nonobese diabetic mice

scientific article published in June 2006

Alpha1-antitrypsin protects beta-cells from apoptosis

scientific article published on 14 March 2007

Anatomical Structures, Cell Types, and Biomarkers Tables Plus 3D Reference Organs in Support of a Human Reference Atlas

scholarly article published 1 June 2021

Anti-thymocyte globulin (ATG) differentially depletes naïve and memory T cells and permits memory-type regulatory T cells in nonobese diabetic mice.

scientific article

Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes.

scientific article

Antigen based therapies to prevent diabetes in NOD mice

scientific article published on 01 June 1996

Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes.

scientific article published on 20 April 2013

Autologous umbilical cord blood infusion for type 1 diabetes

scientific article

Autologous umbilical cord blood transfusion in very young children with type 1 diabetes

scientific article

Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide

scientific article published on 19 October 2011

BCG vaccine-induced neuroprotection in a mouse model of Parkinson's disease

scientific article

Butyrate and type 1 diabetes mellitus: can we fix the intestinal leak?

scientific article published on October 2010

CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes

scientific article

Changes in hippocampal IL-15, related cytokines, and neurogenesis in IL-2 deficient mice

scientific article published in April 2005

Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11

scientific article published on 28 July 2007

Combinatorial delivery of immunosuppressive factors to dendritic cells using dual-sized microspheres

scientific article published on May 2014

Comment on: Brugman S et al. (2006) Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? Diabetologia 49:2105-2108

scientific article published on 21 November 2006

Construction and Usage of a Human Body Common Coordinate Framework Comprising Clinical, Semantic, and Spatial Ontologies

preprint

Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model.

scientific article

Cystic fibrosis transmembrane conductance regulator deficiency exacerbates islet cell dysfunction after beta-cell injury

scientific article published in July 2006

Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity

scientific article published on 21 March 2007

Diabetes acceleration or prevention by a coxsackievirus B4 infection: critical requirements for both interleukin-4 and gamma interferon

scientific article published on January 2005

Dimorphic histopathology of long-standing childhood-onset diabetes

scientific article published on 09 January 2010

Effect of oral and intravenous insulin and glutamic acid decarboxylase in NOD mice

scientific article published on 01 January 1997

Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors

scientific article published in March 2001

Enhanced IgE allergic response to Aspergillus fumigatus in CFTR-/- mice.

scientific article published in February 2006

Exendin-4 Therapy in NOD Mice with New-Onset Diabetes Increases Regulatory T Cell Frequency

scientific article published on 01 December 2008

Exendin-4 treatment of nonobese diabetic mice increases beta-cell proliferation and fractional insulin reactive area

scientific article published on 13 February 2009

Freeze-thaw increases adeno-associated virus transduction of cells

scientific article published in March 2006

Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes

scientific article published on 01 May 2005

Glucose transporter-2 (GLUT2) promoter mediated transgenic insulin production reduces hyperglycemia in diabetic mice

scientific article

Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes

scientific article

Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse

scientific article

Hepatocellular carcinoma immunopathogenesis: clinical evidence for global T cell defects and an immunomodulatory role for soluble CD25 (sCD25).

scientific article

High frequency of abnormal glucose tolerance in DQA1*0102/DQB1*0602 relatives identified as part of the Diabetes Prevention Trial--Type 1 Diabetes

scientific article

Human alpha 1-antitrypsin therapy induces fatal anaphylaxis in non-obese diabetic mice.

scientific article published on 28 August 2008

Hyperghrelinemia in Prader-Willi syndrome begins in early infancy long before the onset of hyperphagia

scientific article published on 29 October 2014

Identification of adeno-associated viral vectors suitable for intestinal gene delivery and modulation of experimental colitis

scientific article published on 23 November 2011

Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice

scientific article published on 23 July 2009

Immune modulation of effector CD4+ and regulatory T cell function by sorafenib in patients with hepatocellular carcinoma.

scientific article published on 07 December 2012

Immunity to adeno-associated virus serotype 2 delivered transgenes imparted by genetic predisposition to autoimmunity

scientific article published in February 2004

Immunization therapies in the prevention of diabetes

scientific article published on 01 June 1997

Impact of humoral immune response on distribution and efficacy of recombinant adeno-associated virus-derived acid alpha-glucosidase in a model of glycogen storage disease type II.

scientific article

Impact of resistant starch on body fat patterning and central appetite regulation.

scientific article

Increased complement activation in human type 1 diabetes pancreata

scientific article published on 16 September 2013

Influence of fecal sample storage on bacterial community diversity.

scientific article published on 24 March 2009

Influence of membrane CD25 stability on T lymphocyte activity: implications for immunoregulation

scientific article

Influence of serum and soluble CD25 (sCD25) on regulatory and effector T-cell function in hepatocellular carcinoma

scientific article published on October 2010

Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function

scientific article published on 08 July 2013

Inhibition of type 1 diabetes correlated to a Lactobacillus johnsonii N6.2-mediated Th17 bias.

scientific article published on 11 February 2011

Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway

scientific article

Interleukin-10+ regulatory B cells arise within antigen-experienced CD40+ B cells to maintain tolerance to islet autoantigens

scientific article

Intradermal alpha1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease

scientific article published in July 2010

Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats

scientific article

Minimal change disease: a dysregulation of the podocyte CD80-CTLA-4 axis?

scientific article

Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation

scientific article published on 26 November 2007

Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development

scientific article

Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes

scientific article

Neurobehavioral changes resulting from recombinase activation gene 1 deletion

scientific article

No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes

scientific article published on 1 March 2007

Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis

scientific article published in September 2005

Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis

scientific article published in January 2006

Novel synthesis of cerium oxide nanoparticles for free radical scavenging

scientific article published on June 2007

Oral delivery of glutamic acid decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD mice

scientific article published on 27 March 2014

PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21).

scientific article published on 18 January 2006

Pancreas organ weight in individuals with disease-associated autoantibodies at risk for type 1 diabetes.

scientific article published in December 2012

Pancreatic adenocarcinoma patients with localised chronic severe pancreatitis show an increased number of single beta cells, without alterations in fractional insulin area

scientific article published on 11 November 2008

Persistent STAT5 phosphorylation and epigenetic dysregulation of GM-CSF and PGS2/COX2 expression in Type 1 diabetic human monocytes

scientific article

Prolonged islet allograft survival by alpha-1 antitrypsin: the role of humoral immunity

scientific article published in March 2008

Rabbit polyclonal mouse antithymocyte globulin administration alters dendritic cell profile and function in NOD mice to suppress diabetogenic responses

scientific article published on April 2009

Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes

scientific article published in December 2004

Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice

scientific article

Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes

scientific article

Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice

scientific article published on 9 April 2012

Serological autoantibody profiling of type 1 diabetes by protein arrays

scientific article published on 20 October 2013

Serum levels of soluble CD25 as a marker for hepatocellular carcinoma

scientific article

Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells.

scientific article published on 29 May 2008

Systemic overexpression of interleukin-10 fails to protect allogeneic islet transplants in nonobese diabetic mice.

scientific article published in August 2005

T regulatory cell function in idiopathic minimal lesion nephrotic syndrome.

scientific article published on 03 June 2009

Taking a daily vitamin to prevent type 1 diabetes?

scientific article published on January 2009

The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings

scientific article

The autoimmune disease-associated SNP rs917997 of IL18RAP controls IFNγ production by PBMC

scientific article published on 24 July 2013

The combined effects on neuronal activation and blood-brain barrier permeability of time and n-3 polyunsaturated fatty acids in mice, as measured in vivo using MEMRI.

scientific article published on 22 January 2010

The relationship between humoral and cellular immunity to IA-2 in IDDM

scientific article published on 01 April 1998

The second murine autoantibody workshop: remarkable interlaboratory concordance for radiobinding assays to identify insulin autoantibodies in nonobese diabetic mice

scientific article published in November 2003

The threshold hypothesis: solving the equation of nurture vs nature in type 1 diabetes.

scientific article published on 20 July 2011

The tyrphostin agent AG490 prevents and reverses type 1 diabetes in NOD mice

scientific article

The use of leptin as treatment for type 1 diabetes mellitus: counterpoint

scientific article published on 02 September 2011

Toward defining the autoimmune microbiome for type 1 diabetes

scientific article

Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice

scientific article

Tyrphostin AG490 agent modestly but significantly prevents onset of type 1 in NOD mouse; implication of immunologic and metabolic effects of a Jak-Stat pathway inhibitor

scientific article published on 4 June 2012

Urinary CD80 excretion increases in idiopathic minimal-change disease

scientific article published on 03 December 2008

Vitamin D levels in subjects with and without type 1 diabetes residing in a solar rich environment

scientific article published on 12 August 2009