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List of works by Stephen Burgess

A comparison of robust Mendelian randomization methods using summary data

scientific article published on 06 April 2020

A cross-platform approach identifies genetic regulators of human metabolism and health

scientific article published on 07 January 2021

A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits

scientific article published in 2021

A review of instrumental variable estimators for Mendelian randomization

scientific article published on 17 August 2015

A robust and efficient method for Mendelian randomization with hundreds of genetic variants

scientific article published on 17 January 2020

ACE inhibition and cardiometabolic risk factors, lung <i>ACE2</i> and <i>TMPRSS2</i> gene expression, and plasma ACE2 levels: a Mendelian randomization study

scientific article published on 18 November 2020

Applying Mendelian randomization to appraise causality in relationships between nutrition and cancer

scientific article published in May 2022

Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization

scientific article published in 2023

Assessing causality in associations between cannabis use and schizophrenia risk: a two-sample Mendelian randomization study.

scientific article published on 08 December 2016

Assessing the causal association of glycine with risk of cardio-metabolic diseases

scientific article published on 05 March 2019

Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis

scientific article published on October 2016

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study ⬇️

scientific article published on 23 February 2017

Association between 25-hydroxyvitamin D and type 2 diabetes--authors' reply

scientific article

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

scientific article (publication date: 15 February 2011)

Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study

scientific article

Association of Cardiometabolic Multimorbidity With Mortality

scientific article

Association of menopausal characteristics and risk of coronary heart disease: a pan-European case–cohort analysis

scientific article published on 01 August 2019

Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian randomization study

scientific article published in 2021

Associations of triglyceride levels with longevity and frailty: A Mendelian randomization analysis

scientific article published on 30 January 2017

Avoiding bias from weak instruments in Mendelian randomization studies

scientific article published on 16 March 2011

BMI as a Modifiable Risk Factor for Type 2 Diabetes: Refining and Understanding Causal Estimates Using Mendelian Randomization

scientific article published on 8 July 2016

Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables

scientific article published on May 2010

Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies

scientific article published on 9 March 2016

Beyond Mendelian randomization: how to interpret evidence of shared genetic predictors

scientific article published on 17 August 2015

Bias due to participant overlap in two-sample Mendelian randomization

scientific article published on 14 September 2016

Bias in causal estimates from Mendelian randomization studies with weak instruments

scientific article

Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses

scientific article published on 26 March 2019

Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study

scientific article published on 01 January 2020

Body mass index and breast cancer survival: a Mendelian randomization analysis

scientific article published in December 2017

Body mass index and risk of dying from a bloodstream infection: A Mendelian randomization study

scientific article published on 16 November 2020

Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study

scientific article published on 01 November 2021

Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods

scientific article

Combining multiple imputation and meta-analysis with individual participant data

scientific article

Commentary

scientific article published in May 2015

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

scientific article

Contextualizing selection bias in Mendelian randomization: how bad is it likely to be?

article

Correction: Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

scientific article published on 17 August 2020

Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language

scientific article published on 24 January 2019

Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators ⬇️

scientific article published on July 17, 2013

Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

scientific article published on 09 March 2022

Erratum to: Interpreting findings from Mendelian randomization using the MR-Egger method.

scientific article

Estimating and contextualizing the attenuation of odds ratios due to non collapsibility

scientific article published on 24 February 2016

Evidence for Shared Genetic Aetiology Between Schizophrenia, Cardiometabolic, and Inflammation-Related Traits: Genetic Correlation and Colocalization Analyses

scientific article published in 2022

Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy.

scientific article published on 27 September 2017

Factorial Mendelian randomization: using genetic variants to assess interactions

scientific article published on 01 August 2019

Genetic Evidence for Repurposing of GLP1R (Glucagon-Like Peptide-1 Receptor) Agonists to Prevent Heart Failure

scientific article

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

scientific article

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

scientific article

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

scientific article

Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation

Genetic predisposition to smoking in relation to 14 cardiovascular diseases

scientific article published on 16 April 2020

Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the <i>GIPR</i> Region

scientific article published on 23 August 2021

Genetically determined height and coronary artery disease

scientific article

Genetically elevated gamma-glutamyltransferase and Alzheimer's disease.

scientific article published on 2 March 2018

Genetically predicted on-statin LDL response is associated with higher intracerebral haemorrhage risk

scientific article published on 22 May 2022

Guidelines for performing Mendelian randomization investigations

scientific article published on 26 November 2019

Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization

scientific article

How humans can contribute to Mendelian randomization analyses

scientific article published on 01 June 2019

IGF-1 and cardiometabolic diseases: a Mendelian randomisation study

scientific article published on 16 June 2020

Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality

scientific article

Identifying the odds ratio estimated by a two‐stage instrumental variable analysis with a logistic regression model ⬇️

scientific article published on June 3, 2013

Impact of Genetically Predicted Red Blood Cell Traits on Venous Thromboembolism: Multivariable Mendelian Randomization Study Using UK Biobank

scientific article published on 08 July 2020

Improving bias and coverage in instrumental variable analysis with weak instruments for continuous and binary outcomes

scientific article published on 29 February 2012

Inflammation and Brain Structure in Schizophrenia and Other Neuropsychiatric Disorders: A Mendelian Randomization Study

scientific article published on 01 May 2022

Instrumental variable analysis with a nonlinear exposure-outcome relationship

scientific article published on November 2014

Interpreting findings from Mendelian randomization using the MR-Egger method

scientific article published on 19 May 2017

Investigating causality in associations between smoking initiation and schizophrenia using Mendelian randomization

scientific article published on 19 January 2017

Investigating causality in the association between 25(OH)D and schizophrenia

scientific article published on 24 May 2016

Iron and hepcidin as risk factors in atherosclerosis: what do the genes say?

scientific article published on 11 July 2015

Lack of identification in semiparametric instrumental variable models with binary outcomes.

scientific article

Lipid traits and type 2 diabetes risk in African ancestry individuals: A Mendelian Randomization study

scientific article published in 2022

Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol-Associated Mechanisms in Etiology of Age-Related Macular Degeneration

scientific article published on 26 April 2017

Mendelian randomization analysis with multiple genetic variants using summarized data

scientific article

Mendelian randomization to assess causal effects of blood lipids on coronary heart disease: lessons from the past and applications to the future

scientific article

Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates

scientific article published on 23 July 2018

Mendelian randomization with fine-mapped genetic data: Choosing from large numbers of correlated instrumental variables

scientific article published on 25 September 2017

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

scientific article published on April 2015

Mendelian randomization: where are we now and where are we going?

scientific article published in April 2015

MendelianRandomization v0.5.0: updates to an R package for performing Mendelian randomization analyses using summarized data

scientific article published on 22 October 2020

MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data

scientific article

Methods for meta-analysis of individual participant data from Mendelian randomisation studies with binary outcomes

scientific article

Missing data methods in Mendelian randomization studies with multiple instruments

scientific article

Modal-based estimation via heterogeneity-penalized weighting: model averaging for consistent and efficient estimation in Mendelian randomization when a plurality of candidate instruments are valid

scientific article published on 26 May 2018

Moderate alcohol drinking in pregnancy increases risk for children's persistent conduct problems: causal effects in a Mendelian randomisation study

scientific article

Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects

scientific article published on 27 January 2015

Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis

scientific article

Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways

scientific article

Noise-augmented directional clustering of genetic association data identifies distinct mechanisms underlying obesity

scientific article published on 27 January 2022

PhenoScanner: a database of human genotype-phenotype associations.

scientific article published on 17 June 2016

Plasma urate and coronary heart disease: fingerprint match, but no smoking gun.

scientific article published on 15 January 2016

Polygenic modelling of treatment effect heterogeneity

scientific article published on 10 August 2020

Predicting the Direction of Causal Effect Based on an Instrumental Variable Analysis: A Cautionary Tale

scientific article published on 14 January 2016

Predicting the effect of statins on cancer risk using genetic variants from a Mendelian randomization study in the UK Biobank

scientific article published on 13 October 2020

Re: "Credible Mendelian Randomization Studies: Approaches For Evaluating The Instrumental Variable Assumptions"

scientific article published on 31 July 2012

Re: “Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects”

scientific article published on 5 February 2015

Response to Hartwig and Davies

scientific article published on 20 September 2016

Robust methods in Mendelian randomization via penalization of heterogeneous causal estimates

scientific article published on 23 September 2019

Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome

scientific article published on 6 March 2014

Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization

scientific article published on 07 January 2020

Semiparametric methods for estimation of a nonlinear exposure-outcome relationship using instrumental variables with application to Mendelian randomization

scientific article

Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants

scientific article published on 26 September 2016

Serum gamma-glutamyl transferase and risk of type 2 diabetes in the general Korean population: a Mendelian randomization study

scientific article published on 27 July 2016

Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

scientific article published on 19 March 2019

Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants

scientific article published on 23 July 2020

Software Application Profile: SUMnlmr, an R package that facilitates flexible and reproducible non-linear Mendelian randomization analyses

scientific article published in 2022

The MR-Base platform supports systematic causal inference across the human phenome.

scientific article published on 30 May 2018

The association between genetically elevated polyunsaturated fatty acids and risk of cancer

scientific article published in May 2023

The association between low-density lipoprotein cholesterol predicted by HMGCR genetic variants and breast cancer risk may be mediated by body mass index

The association between weight at birth and breast cancer risk revisited using Mendelian randomisation

The association between weight at birth and breast cancer risk revisited using Mendelian randomisation

The many weak instruments problem and Mendelian randomization

scientific article published on 10 November 2014

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.

scientific article

Use of Mendelian randomisation to assess potential benefit of clinical intervention

scientific article

Use of allele scores as instrumental variables for Mendelian randomization

scientific article published on August 2013

Using Mendelian randomization to assess and develop clinical interventions: limitations and benefits.

scientific article

Using human genetics to understand the disease impacts of testosterone in men and women

scientific article published on 10 February 2020

Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions

scientific article

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

scientific article

Vitamin D and high blood pressure: causal association or epiphenomenon?

scientific article published on 29 December 2013

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality:

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