List of works - Rodrigo Medeiros

Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.

scientific article

Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea

scientific article

Aspirin-triggered lipoxin A4 stimulates alternative activation of microglia and reduces Alzheimer disease-like pathology in mice

scientific article published on 16 March 2013

Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony

scientific article published on 11 October 2012

Blockade of hippocampal bradykinin B1 receptors improves spatial learning and memory deficits in middle-aged rats

scientific article published on 24 August 2016

Bradykinin B1 receptor expression induced by tissue damage in the rat portal vein: a critical role for mitogen-activated protein kinase and nuclear factor-kappaB signaling pathways

scientific article

B₂ receptor blockage prevents Aβ-induced cognitive impairment by neuroinflammation inhibition.

scientific article published on 3 November 2014

Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice

scientific article published on 9 June 2012

Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's disease.

scientific article published on 16 April 2015

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

scientific article published in August 2015

Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein.

scientific article

Copper Exposure Perturbs Brain Inflammatory Responses and Impairs Clearance of Amyloid-Beta

scientific article published on 27 April 2016

Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response

scientific article published on 27 December 2006

Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw.

scientific article published on 30 April 2007

Effects of kinin B(1) and B(2) receptor antagonists on overactive urinary bladder syndrome induced by spinal cord injury in rats

scientific article

Elucidating the triggers, progression, and effects of Alzheimer's disease

scientific article published on January 2013

Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition.

scientific article published on 29 October 2013

Endothelium dependent expression and underlying mechanisms of des-Arg⁹-bradykinin-induced B₁R-mediated vasoconstriction in rat portal vein.

scientific article published on 31 July 2012

Folic Acid Plus α-Tocopherol Mitigates Amyloid-β-Induced Neurotoxicity through Modulation of Mitochondrial Complexes Activity

scientific article published on 01 January 2011

Genetic ablation of tau mitigates cognitive impairment induced by type 1 diabetes

scientific article published on 07 January 2014

Genetic deletion or antagonism of kinin B(1) and B(2) receptors improves cognitive deficits in a mouse model of Alzheimer's disease.

scientific article

Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus

scientific article published on 23 December 2010

Inflammation induced by infection potentiates tau pathological features in transgenic mice

scientific article

Inflammation: the link between comorbidities, genetics, and Alzheimer's disease

article

Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus

scientific article published on 04 November 2019

Involvement of phosphoinositide 3-kinase gamma in the neuro-inflammatory response and cognitive impairments induced by beta-amyloid 1-40 peptide in mice

scientific article published on 16 December 2009

Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes

scientific article

Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline

scientific article published on 23 June 2011

Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice.

scientific article published in September 2005

Mechanisms underlying lipopolysaccharide-induced kinin B1 receptor up-regulation in the pig iris sphincter in vitro.

scientific article published on 7 February 2006

Mechanisms underlying the inhibitory actions of the pentacyclic triterpene α-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate

scientific article published on 29 December 2006

Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw

scientific journal article

Mechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro.

scientific article

Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.

scientific article published on 8 January 2013

Molecular mechanisms of topical anti-inflammatory effects of lipoxin A(4) in endotoxin-induced uveitis.

scientific article published on 15 April 2008

Neuropathic Pain-Like Behavior after Brachial Plexus Avulsion in Mice: The Relevance of Kinin B1 and B2 Receptors

scientific article published on 01 March 2008

PAF-induced kinin B1 receptor in vivo up-regulation: involvement of distinct kinase pathways

Preventive and therapeutic anti-inflammatory effects of systemic and topical thalidomide on endotoxin-induced uveitis in rats

scientific article published on 12 January 2007

Reduced skin inflammatory response in mice lacking inducible nitric oxide synthase

scientific article published on 3 May 2009

Repeated Physical Training and Environmental Enrichment Induce Neurogenesis and Synaptogenesis Following Neuronal Injury in an Inducible Mouse Model

Restoration of lipoxin A4 signaling reduces Alzheimer's disease-like pathology in the 3xTg-AD mouse model

scientific article published in January 2015

Risk is in the air: an intranasal MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) rat model of Parkinson's disease

scientific article published in July 2009

Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptide

scientific article

Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice

scientific article published on 16 June 2015

The bradykinin B1 receptor regulates Aβ deposition and neuroinflammation in Tg-SwDI mice

scientific article published on 5 March 2013

The effects of diacerhein on mechanical allodynia in inflammatory and neuropathic models of nociception in mice.

scientific article published in December 2005

The novel calpain inhibitor A-705253 prevents stress-induced tau hyperphosphorylation in vitro and in vivo

scientific article published on 18 May 2012

The risk is in the air: Intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease.

scientific article published on 14 August 2006

The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice

scientific journal article

The role of TNF-alpha signaling pathway on COX-2 upregulation and cognitive decline induced by beta-amyloid peptide

scientific article published in February 2010

The role of kinin B1 receptors in the nociception produced by peripheral protein kinase C activation in mice

scientific article published on 22 November 2007

The role of tau in Alzheimer's disease and related disorders

scientific article published on 14 June 2010

The selective and competitive N-methyl-D-aspartate receptor antagonist, (-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid, prevents synaptic toxicity induced by amyloid-β in mice

scientific article

Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions

scientific article published on January 2012

p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice

scientific article published on 2 June 2014

α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles

scientific article published on 19 November 2013

List of works by Rodrigo Medeiros

Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.

Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea

Aspirin-triggered lipoxin A4 stimulates alternative activation of microglia and reduces Alzheimer disease-like pathology in mice

Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony

Blockade of hippocampal bradykinin B1 receptors improves spatial learning and memory deficits in middle-aged rats

Bradykinin B1 receptor expression induced by tissue damage in the rat portal vein: a critical role for mitogen-activated protein kinase and nuclear factor-kappaB signaling pathways

B₂ receptor blockage prevents Aβ-induced cognitive impairment by neuroinflammation inhibition.

Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice

Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's disease.

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein.

Copper Exposure Perturbs Brain Inflammatory Responses and Impairs Clearance of Amyloid-Beta

Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response

Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw.

Effects of kinin B(1) and B(2) receptor antagonists on overactive urinary bladder syndrome induced by spinal cord injury in rats

Elucidating the triggers, progression, and effects of Alzheimer's disease

Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition.

Endothelium dependent expression and underlying mechanisms of des-Arg⁹-bradykinin-induced B₁R-mediated vasoconstriction in rat portal vein.

Folic Acid Plus α-Tocopherol Mitigates Amyloid-β-Induced Neurotoxicity through Modulation of Mitochondrial Complexes Activity

Genetic ablation of tau mitigates cognitive impairment induced by type 1 diabetes

Genetic deletion or antagonism of kinin B(1) and B(2) receptors improves cognitive deficits in a mouse model of Alzheimer's disease.

Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus

Inflammation induced by infection potentiates tau pathological features in transgenic mice

Inflammation: the link between comorbidities, genetics, and Alzheimer's disease

Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus

Involvement of phosphoinositide 3-kinase gamma in the neuro-inflammatory response and cognitive impairments induced by beta-amyloid 1-40 peptide in mice

Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes

Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline

Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice.

Mechanisms underlying lipopolysaccharide-induced kinin B1 receptor up-regulation in the pig iris sphincter in vitro.

Mechanisms underlying the inhibitory actions of the pentacyclic triterpene α-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate

Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw

Mechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro.

Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.

Molecular mechanisms of topical anti-inflammatory effects of lipoxin A(4) in endotoxin-induced uveitis.

Neuropathic Pain-Like Behavior after Brachial Plexus Avulsion in Mice: The Relevance of Kinin B1 and B2 Receptors

PAF-induced kinin B1 receptor in vivo up-regulation: involvement of distinct kinase pathways

Preventive and therapeutic anti-inflammatory effects of systemic and topical thalidomide on endotoxin-induced uveitis in rats

Reduced skin inflammatory response in mice lacking inducible nitric oxide synthase

Repeated Physical Training and Environmental Enrichment Induce Neurogenesis and Synaptogenesis Following Neuronal Injury in an Inducible Mouse Model

Restoration of lipoxin A4 signaling reduces Alzheimer's disease-like pathology in the 3xTg-AD mouse model

Risk is in the air: an intranasal MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) rat model of Parkinson's disease

Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptide

Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice

The bradykinin B1 receptor regulates Aβ deposition and neuroinflammation in Tg-SwDI mice

The effects of diacerhein on mechanical allodynia in inflammatory and neuropathic models of nociception in mice.

The novel calpain inhibitor A-705253 prevents stress-induced tau hyperphosphorylation in vitro and in vivo

The risk is in the air: Intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease.

The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice

The role of TNF-alpha signaling pathway on COX-2 upregulation and cognitive decline induced by beta-amyloid peptide

The role of kinin B1 receptors in the nociception produced by peripheral protein kinase C activation in mice

The role of tau in Alzheimer's disease and related disorders

The selective and competitive N-methyl-D-aspartate receptor antagonist, (-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid, prevents synaptic toxicity induced by amyloid-β in mice

Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions

p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice

α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles