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List of works by Stefano Cascinu

5-Fluorouracil pharmacogenomics: still rocking after all these years?

scientific article published on February 2011

A Dose-finding and Biomarker Evaluation Phase Ib Study of Everolimus in Association With 5-Fluorouracil and Pelvic Radiotherapy as Neoadjuvant Treatment of Locally Advanced Rectal Cancer (E-LARC Study).

scientific article published on 24 March 2017

A combination of a fixed dose rate infusion of gemcitabine associated to a bolus 5-fluorouracil in advanced pancreatic cancer, a report from the Italian Group for the Study of Digestive Tract Cancer (GISCAD).

scientific article

A combination of gemcitabine and 5-fluorouracil in advanced pancreatic cancer, a report from the Italian Group for the Study of Digestive Tract Cancer (GISCAD).

scientific article

A multi-centre retrospective review of second-line therapy in advanced pancreatic adenocarcinoma.

scientific article published on 03 January 2008

A novel approach to manage skin toxicity caused by therapeutic agents targeting epidermal growth factor receptor.

scientific article

A phase I study of paclitaxel and 5-fluorouracil in advanced gastric cancer ⬇️

scientific article published on September 1, 1997

A phase I, dose-escalation study of volasertib combined with nintedanib in advanced solid tumors

scientific article published on 22 September 2015

A phase I-II study of gemcitabine and docetaxel in advanced pancreatic cancer: a report from the Italian Group for the Study of Digestive Tract Cancer (GISCAD).

scientific article

A phase II study of neoadjuvant bevacizumab plus capecitabine and concomitant radiotherapy in patients with locally advanced rectal cancer

scientific article published on 03 January 2012

A phase II study of the L19IL2 immunocytokine in combination with dacarbazine in advanced metastatic melanoma patients

scientific article published on 03 September 2019

A phase II study of weekly cisplatin, 6S-stereoisomer leucovorin and fluorouracil as first-line chemotherapy for elderly patients with advanced gastric cancer ⬇️

scientific article published on October 20, 2003

A phase II study to evaluate LY2603618 in combination with gemcitabine in pancreatic cancer patients.

scientific article

A validated prognostic classifier for V600EBRAF-mutated metastatic colorectal cancer: the 'BRAF BeCool' study

scientific article published on 19 July 2019

ANGPT2 and NOS3 Polymorphisms and Clinical Outcome in Advanced Hepatocellular Carcinoma Patients Receiving Sorafenib

scientific article published on 20 July 2019

Addressing the challenges of pancreatic cancer: future directions for improving outcomes

scientific article published on 17 October 2014

Adjuvant chemotherapy in colon cancer: can we improve quality of care?

scientific article published on 17 July 2013

Adjuvant chemotherapy in completely resected gastric cancer: a randomized phase III trial conducted by GOIRC.

scientific article

Adjuvant treatment of high-risk, radically resected gastric cancer patients with 5-fluorouracil, leucovorin, cisplatin, and epidoxorubicin in a randomized controlled trial.

scientific article published in April 2007

Advanced digestive neuroendocrine tumors: metastatic pattern is an independent factor affecting clinical outcome.

scientific article published in March 2014

Aflibercept, a New Way to Target Angiogenesis in the Second Line Treatment of Metastatic Colorectal Cancer (mCRC).

scientific article

Allele polymorphisms of tumor integrins correlate with peritoneal carcinosis capability of gastric cancer cells in radically resected patients

scientific article published on 06 October 2010

Altering macrophage polarization in the tumor environment: the role of response gene to complement 32.

scientific article published on 24 November 2014

Alternative dosing schedules for sunitinib as a treatment of patients with metastatic renal cell carcinoma.

scientific article

An Italian cost-effectiveness analysis of paclitaxel albumin (nab-paclitaxel) + gemcitabine vs gemcitabine alone for metastatic pancreatic cancer patients: the APICE study.

scientific article

An expanded access program of erlotinib (Tarceva) in patients with advanced non-small cell lung cancer (NSCLC): data report from Italy

scientific article

Anal cancer: from an orphan disease to a curable malignancy?

scientific article published on 20 February 2017

Analysis of HER-3, insulin growth factor-1, nuclear factor-kB and epidermal growth factor receptor gene copy number in the prediction of clinical outcome for K-RAS wild-type colorectal cancer patients receiving irinotecan-cetuximab.

scientific article published on 23 November 2011

Androgen receptor expression in early triple-negative breast cancer: clinical significance and prognostic associations

scientific article

Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients.

scientific article published on 27 April 2016

Angiogenesis genotyping in the selection of first-line treatment with either sunitinib or pazopanib for advanced renal cell carcinoma.

scientific article published on 09 May 2016

Angiogenesis in pancreatic ductal adenocarcinoma: A controversial issue

scientific article published on 21 July 2016

Anti-EGFR strategies as an incremental step for the treatment of colorectal cancer patients: moving from scientific evidence to clinical practice.

scientific article

Anti-EGFR therapy in oesophagogastric cancer: precise but not enough

scientific article published on 01 August 2018

Are post-docetaxel treatments effective in patients with castration-resistant prostate cancer and performance of 2? A meta-analysis of published trials.

scientific article published on 30 July 2013

Are we ready to describe response or progression to immunotherapy in lung cancer?

scientific article published on 04 April 2019

Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer

scientific article published in November 2002

Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy.

scientific article

Association of thymidylate synthase polymorphisms with gastric cancer susceptibility

scientific article published in December 2004

Atrial fibrillation in patients with active malignancy and use of anticoagulants: Under-prescription but no adverse impact on all-cause mortality

scientific article published on 29 October 2018

BAP1, PBRM1 and SETD2 in clear-cell renal cell carcinoma: molecular diagnostics and possible targets for personalized therapies

scientific article published on 11 July 2015

BRAF, NRAS and C-KIT Advanced Melanoma: Clinico-pathological Features, Targeted-Therapy Strategies and Survival

scientific article published in December 2017

Basal and bevacizumab-based therapy-induced changes of lactate dehydrogenases and fibrinogen levels and clinical outcome of previously untreated metastatic colorectal cancer patients: a multicentric retrospective analysis.

scientific article

Biological parameters on computed tomography guided fine needle aspiration biopsy from peripheral primary non-small cell lung cancer

scientific article published on March 2002

Biological predictive factors in rectal cancer treated with preoperative radiotherapy or radiochemotherapy

scientific article published on 18 December 2007

Bone metastases in patients with metastatic renal cell carcinoma: are they always associated with poor prognosis?

scientific article

Borderline resectable pancreatic cancer: More than an anatomical concept

scientific article published on 05 December 2016

Breast ultrasonography (BU) in the screening protocol for women at hereditary-familial risk of breast cancer: has the time come to rethink the role of BU according to different risk categories?

scientific article published on 04 October 2018

COX-2 and NF-KB overexpression is common in pancreatic cancer but does not predict for COX-2 inhibitors activity in combination with gemcitabine and oxaliplatin.

scientific article published in October 2007

CXC and CC chemokines as angiogenic modulators in nonhaematological tumors.

scientific article published on 29 May 2014

Cancer stem cell gene profile as predictor of relapse in high risk stage II and stage III, radically resected colon cancer patients

scientific article

Carcinoma of pancreatic body and tail: are there improvements in diagnosis and treatment modalities over the past decade?

scientific article published in June 2003

Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trial

scientific article published in January 2008

Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status

scientific article (publication date: 20 May 2011)

Cetuximab rechallenge in metastatic colorectal cancer patients: how to come away from acquired resistance?

scientific article

Cetuximab: still an option in the treatment of pancreatic cancer? ⬇️

scientific article published on May 1, 2013

Chemotherapy for advanced gastric cancer: across the years for a standard of care

scientific article

Chemotherapy for advanced pancreatic cancer: it may no longer be ignored

scientific article

Chemotherapy-free intervals in patients with metastatic colorectal cancer: a tale of two cities?

scientific article published on 12 April 2010

Chromium exposure and germinal embryonal carcinoma: first two cases and review of the literature.

scientific article

Class 1, 2, and 3 BRAF-Mutated Metastatic Colorectal Cancer: A Detailed Clinical, Pathologic, and Molecular Characterization

scientific article published on 09 April 2019

Clinical Benefit and Health-Related Quality of Life Assessment in Patients Treated with Cisplatin/S-1 Versus Cisplatin/5-FU: Secondary End Point Results From the First-Line Advanced Gastric Cancer Study (FLAGS).

scientific article published in June 2015

Clinical and molecular predictors of long-term response in HER2 positive metastatic breast cancer patients

scientific article published on 01 August 2018

Clinical and pathologic predictors of clinical outcome of malignant pleural mesothelioma.

scientific article

Clinical evidence for three distinct gastric cancer subtypes: time for a new approach

scientific article

Clinical impact of different exosomes' protein expression in pancreatic ductal carcinoma patients treated with standard first line palliative chemotherapy

scientific article published on 02 May 2019

Clinical predictive factors for advanced non-small cell lung cancer (NSCLC) patients receiving third-line therapy: Selecting the unselectable?

scientific article published on 6 August 2009

Combination of cisplatin/S-1 in the treatment of patients with advanced gastric or gastroesophageal adenocarcinoma: Results of noninferiority and safety analyses compared with cisplatin/5-fluorouracil in the First-Line Advanced Gastric Cancer Study ⬇️

scientific article published on July 27, 2013

Combined Hormonal Contraceptive Use and Risk of Breast Cancer in a Population of Women With a Family History.

scientific article published on 14 November 2017

Combined analysis of E-cadherin gene (CDH1) promoter hypermethylation and E-cadherin protein expression in patients with gastric cancer: implications for treatment with demethylating drugs.

scientific article published in March 2004

Computational analysis of the mutations in BAP1, PBRM1 and SETD2 genes reveals the impaired molecular processes in renal cell carcinoma

scientific article

Conditional survival of patients treated with first-line chemotherapy for metastatic urothelial cancer

scientific article published on 24 October 2014

Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal-Cell Carcinoma Treated With Everolimus.

scientific article

Current Histopathologic and Molecular Characterisations of Prostate Cancer: Towards Individualised Prognosis and Therapies

scientific article

Cutaneous seeding after ultrasound-guided percutaneous ethanol injection for treatment of hepatocellular carcinoma.

scientific article

Dabrafenib-trametinib combination in 'field-practice': an Italian experience

scientific article published on 07 August 2018

Diagnosis, Management and Clinical Outcome of Bone Metastases in Breast Cancer Patients: Results from a Prospective, Multicenter Study

scientific article published on 01 January 2006

Differences of vascular endothelial growth factor (VEGF) expression between liver and abdominal metastases from colon cancer. Implications for the treatment with VEGF inhibitors

scientific article published on 01 January 2000

Different doses of pamidronate in patients with painful osteolytic bone metastases.

scientific article

Differential molecular pathways expression in HER2 positive early breast cancer according to hormone receptor status

scientific article published on 02 January 2019

Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.

scientific article

Drug therapy in diarrheal diseases in oncology/hematology patients ⬇️

scientific article published on January 1, 1995

Early Integration of Palliative Care in Oncology Practice: Results of the Italian Association of Medical Oncology (AIOM) Survey

scientific article published on 27 September 2016

Early onset of hypertension and serum electrolyte changes as potential predictive factors of activity in advanced HCC patients treated with sorafenib: results from a retrospective analysis of the HCC-AVR group

scientific article published on 17 February 2016

Effective prevention of 5-fluorouracil-induced superficial phlebitis by ketoprofen lysine salt gel.

scientific article published in October 2003

Effects of metformin on clinical outcome in diabetic patients with advanced HCC receiving sorafenib

scientific article published on 29 October 2015

Efficacy and safety of second-line fotemustine in elderly patients with recurrent glioblastoma

scientific article

Efficacy of adjuvant chemotherapy after curative resection for gastric cancer: a meta-analysis of published randomised trials. A study of the GISCAD (Gruppo Italiano per lo Studio dei Carcinomi dell'Apparato Digerente).

scientific article

Emerging Immunotargets in Bladder Cancer.

scientific article

Emerging Immunotargets in Metastatic Renal Cell Carcinoma.

scientific article

Emerging antibodies for the treatment of pancreatic cancer.

scientific article published on 28 February 2017

Emerging concepts on drug resistance in bladder cancer: Implications for future strategies.

scientific article published on 15 May 2015

Emerging role of tumor-associated macrophages as therapeutic targets in patients with metastatic renal cell carcinoma.

scientific article published on 17 October 2013

Emerging strategies to overcome the resistance to current mTOR inhibitors in renal cell carcinoma.

scientific article published on 27 January 2014

Epidermal Growth Factor Receptor (EGFR) gene copy number (GCN) correlates with clinical activity of irinotecan-cetuximab in K-RAS wild-type colorectal cancer: a fluorescence in situ (FISH) and chromogenic in situ hybridization (CISH) analysis

scientific article published on 27 August 2009

Epidermal growth factor receptor (EGFR) downstream signalling pathway in primary colorectal tumours and related metastatic sites: optimising EGFR-targeted treatment options.

scientific article published on 19 June 2007

Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients.

scientific article

Epidermal growth factor receptor (EGFR) status in primary colorectal tumors does not correlate with EGFR expression in related metastatic sites: implications for treatment with EGFR-targeted monoclonal antibodies.

scientific article published in December 2004

Epidermal growth factor receptor gene copy number and clinical outcome of metastatic colorectal cancer treated with panitumumab

scientific article published on 01 August 2007

Erratum to: Aflibercept, a New Way to Target Angiogenesis in the Second Line Treatment of Metastatic Colorectal Cancer (mCRC).

scientific article

Essential role of Gli proteins in glioblastoma multiforme.

scientific article published on March 2013

Everolimus and exemestane in long survival hormone receptor positive male breast cancer: case report.

scientific article

Everolimus and temsirolimus are not the same second-line in metastatic renal cell carcinoma. A systematic review and meta-analysis of literature data

scientific article

Evolving strategies for the treatment of hepatocellular carcinoma: from clinical-guided to molecularly-tailored therapeutic options.

scientific article published on 25 August 2010

FOLFIRI as second-line chemotherapy for advanced pancreatic cancer: a GISCAD multicenter phase II study

scientific article published on 11 May 2012

Final results and outcomes by prior bevacizumab exposure, skin toxicity, and hypomagnesaemia from ASPECCT: randomized phase 3 non-inferiority study of panitumumab versus cetuximab in chemorefractory wild-type KRAS exon 2 metastatic colorectal cancer

scientific article published on 4 October 2016

First-Line Treatment for Endocrine-Sensitive Bone-Only Metastatic Breast Cancer: Systematic Review and Meta-analysis

scientific article published on 24 July 2019

First-line FOLFIRI and bevacizumab in patients with advanced colorectal cancer prospectively stratified according to serum LDH: final results of the GISCAD (Italian Group for the Study of Digestive Tract Cancers) CENTRAL (ColorEctalavastiNTRiAlLdh)

scientific article published on 19 September 2017

GD2 expression in breast cancer.

scientific article

Gastric cancer: Translating novels concepts into clinical practice

scientific article published on 14 August 2019

Gastric cancer: toward a cisplatin-free disease?

scientific article published on August 2014

Gastric carcinoma: an evolutionary scenario

scientific article published in March 2017

Gastro-entero-pancreatic neuroendocrine tumors: Is now time for a new approach?

scientific article published on April 2016

Gastrointestinal cancer refractory to chemotherapy: a role for octreotide?

scientific article

Gastrointestinal neuroendocrine tumors: Searching the optimal treatment strategy--A literature review

scientific article

Gemcitabine and oxaliplatin: a safe and active regimen in poor prognosis advanced non-small cell lung cancer patients

scientific article

Gender differences and outcome of melanoma patients.

scientific article published on 15 January 2015

HER family receptor expression and prognosis in pancreatic cancer.

scientific article

HER-2/neu amplification by fluorescence in situ hybridization in cytologic samples from distant metastatic sites of breast carcinoma ⬇️

scientific article published on October 25, 2003

HER-2/neu amplification detected by fluorescence in situ hybridization in fine needle aspirates from primary breast cancer

scientific article published on 01 September 2002

Heavily calcified gastrointestinal stromal tumors: Pathophysiology and implications of a rare clinicopathologic entity

scientific article published on March 2017

Hepatocellular carcinoma: The beginning of a long journey.

scientific article published on 21 August 2009

Hereditary Pancreatic Cancer: A Retrospective Single-Center Study of 5143 Italian Families with History of BRCA-Related Malignancies

article

Heterogeneous drug target expression as possible basis for different clinical and radiological response to the treatment of primary and metastatic renal cell carcinoma: suggestions from bench to bedside

scientific article published on March 2014

High Neutrophil-to-lymphocyte Ratio Persistent During First-line Chemotherapy Predicts Poor Clinical Outcome in Patients with Advanced Urothelial Cancer

scientific article published on 19 September 2014

High curative resection rate with weekly cisplatin, 5-fluorouracil, epidoxorubicin, 6S-leucovorin, glutathione, and filgastrim in patients with locally advanced, unresectable gastric cancer: a report from the Italian Group for the Study of Digestive

scientific article

Highlights from the ASCO Genitourinary Symposium 2014: focus on renal and prostate cancer

scientific article published on 27 August 2014

Highlights of the EORTC St. Gallen International Expert Consensus on the primary therapy of gastric, gastroesophageal and oesophageal cancer - differential treatment strategies for subtypes of early gastroesophageal cancer.

scientific article published on 23 August 2012

Hormonal receptors in lung adenocarcinoma: expression and difference in outcome by sex ⬇️

scientific article published on 26 September 2016

Hyponatraemia is a predictor of clinical outcome for malignant pleural mesothelioma

scientific article published on 21 August 2014

Hyponatremia in cancer patients: Time for a new approach.

scientific article published on 10 March 2016

Hyponatremia is a predictor of hospital length and cost of stay and outcome in cancer patients.

scientific article

Hyponatremia normalization as an independent prognostic factor in patients with advanced non-small cell lung cancer treated with first-line therapy

scientific article

Immune inflammation indicators in anal cancer patients treated with concurrent chemoradiation: training and validation cohort with online calculator (ARC: Anal Cancer Response Classifier)

scientific article published on 26 April 2019

Immunotherapy in Dialysis-Dependent Cancer Patients: Our Experience in Patients With Metastatic Renal Cell Carcinoma and a Review of the Literature

scientific article published on 08 July 2019

Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy

scientific article

Impact of laterality and mucinous histology on relapse-free and overall survival in a registry-based colon cancer series

scientific article published on 06 March 2019

Impact of time to surgery after neoadjuvant chemotherapy in operable breast cancer patients

scientific article published on 20 October 2016

Increased rates of local complication of central venous catheters in the targeted anticancer therapy era: a 2-year retrospective analysis.

scientific article published on 19 October 2014

Infusional 5-fluorouracil, cisplatin and mitomycin C in advanced gastric cancer: a low cost effective regimen

scientific article

Inhibition of tumor cell kinetics and serum insulin growth factor I levels by octreotide in colorectal cancer patients ⬇️

scientific article published on 01 September 1997

Inside the 2015 ASCO Genitourinary Cancers Symposium.

scientific article published in July 2015

Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients

scientific article published on 27 March 2008

Insulin-like growth factor 1 expression correlates with clinical outcome in K-RAS wild type colorectal cancer patients treated with cetuximab and irinotecan.

scientific article published in October 2010

Intensive weekly chemotherapy is not effective in advanced pancreatic cancer patients: a report from the Italian Group for the Study of Digestive Tract Cancer (GISCAD).

scientific article

Interleukin 1B gene (IL-1B) and interleukin 1 receptor antagonist gene (IL-1RN) polymorphisms in Helicobacter pylori-negative gastric cancer of intestinal and diffuse histotype.

scientific article

Investigational therapies targeting signal transducer and activator of transcription 3 for the treatment of cancer

scientific article

Ipsilateral supraclavicular lymph nodes metastases from breast cancer as only site of disseminated disease. Chemotherapy alone vs. induction chemotherapy to radical radiation therapy

scientific article published on 01 August 2001

Is there a role for chemotherapy after local relapse in high-grade osteosarcoma?

scientific article published on 06 May 2019

Is there a role for surgical resection in patients with pancreatic cancer with liver metastases responding to chemotherapy?

scientific article published on 29 June 2016

Italian Nivolumab Expanded Access Program in Nonsquamous Non–Small Cell Lung Cancer Patients: Results in Never-Smokers and EGFR-Mutant Patients

article

KIT and PDGFRalpha mutations in 104 patients with gastrointestinal stromal tumors (GISTs): a population-based study

scientific article published on 10 January 2008

KRAS mutation status is associated with specific pattern of genes expression in pancreatic adenocarcinoma

scientific article

Lactate Dehydrogenase in Hepatocellular Carcinoma: Something Old, Something New

scientific article

Late Gastrointestinal Toxicity During Nivolumab Therapy in Non-Small Cell Lung Cancer: A Rare Case of Inflammatory Bowel Disease

scientific article published on 01 August 2018

Lenvatinib as a therapy for unresectable hepatocellular carcinoma

scientific article published on 21 September 2018

Lgr5 expression, cancer stem cells and pancreatic cancer: results from biological and computational analyses

scientific article published on January 2015

Locally Advanced Rectal Cancer Patients Receiving Radio-Chemotherapy: A Novel Clinical–Pathologic Score Correlates With Global Outcome

scientific article published on 20 April 2009

Locally advanced rectal cancer: the importance of a multidisciplinary approach.

scientific article

Locally advanced versus metastatic pancreatic cancer: two different diseases with two different treatment approaches?

scientific article published on September 2013

Locoregional treatments of unresectable liver metastases from colorectal cancer

scientific article published on 01 February 1998

Maintenance therapy for metastatic colorectal cancer

scientific article published on 08 September 2015

Metabolic alterations in renal cell carcinoma

scientific article published on 09 July 2015

Metformin and insulin impact on clinical outcome in patients with advanced hepatocellular carcinoma receiving sorafenib: Validation study and biological rationale.

scientific article

Metronomic Capecitabine Effectively Blocks Leptomeningeal Carcinomatosis From Breast Cancer: A Case Report and Literature Review.

scientific article published on 28 February 2017

Metronomic capecitabine versus best supportive care as second-line treatment in hepatocellular carcinoma: a retrospective study

scientific article published on 13 February 2017

MicroRNA in pancreatic adenocarcinoma: predictive/prognostic biomarkers or therapeutic targets?

scientific article (publication date: 15 September 2015)

Mismatch repair deficiency may affect clinical outcome through immune response activation in metastatic gastric cancer patients receiving first-line chemotherapy.

scientific article published on 21 January 2016

Mismatch repair system (MMR) status correlates with response and survival in non-small cell lung cancer (NSCLC) patients

scientific article published in July 2006

Molecular Biomarkers for Prediction of Targeted Therapy Response in Metastatic Breast Cancer: Trick or Treat?

scientific article published on 04 January 2017

Molecular biology for stage II colorectal cancer: the jury is still out

scientific article published on 01 July 2007

Molecular biology of sporadic gastric cancer: prognostic indicators and novel therapeutic approaches.

scientific article published in August 2004

Molecular markers predictive of response to chemotherapy in gastrointestinal tumors.

scientific article

Mucinous Rectal Adenocarcinoma Can Be Associated to Tumor Downstaging after Preoperative Chemoradiotherapy

scientific article published on 01 October 2007

Multicenter Prospective Study of Angiogenesis Polymorphism Validation in HCC Patients Treated with Sorafenib. An INNOVATE Study Protocol

scientific article published on 09 May 2018

Multidisciplinary treatment of locally advanced rectal cancer: a literature review. Part 1.

scientific article published on October 2009

Multimodal treatment of resectable pancreatic ductal adenocarcinoma.

scientific article published on 4 February 2017

Mutational Profile of Metastatic Breast Cancer Tissue in Patients Treated with Exemestane Plus Everolimus

scientific article published on 24 July 2018

Natural history of bone metastasis in colorectal cancer: final results of a large Italian bone metastases study

scientific article published on 4 January 2012

Natural history of malignant bone disease in hepatocellular carcinoma: final results of a multicenter bone metastasis survey.

scientific article

Neoadjuvant chemotherapy in advanced gastric and esophago-gastric cancer. Meta-analysis of randomized trials.

scientific article published on 27 January 2018

Neoadjuvant multimodal treatment of pancreatic ductal adenocarcinoma

scientific article

Neoadjuvant therapy in pancreatic cancer: an emerging strategy

scientific article

Neoadjuvant treatments in triple-negative breast cancer patients: where we are now and where we are going

scientific article published on 15 January 2018

Neuroendocrine differentiation in prostate cancer: novel morphological insights and future therapeutic perspectives.

scientific article

Neuroprotective effect of reduced glutathione on oxaliplatin-based chemotherapy in advanced colorectal cancer: a randomized, double-blind, placebo-controlled trial

scientific article published in August 2002

Neutrophil-to-lymphocyte ratio may be associated with the outcome in patients with prostate cancer.

scientific article

New findings on thymic epithelial tumors: Something is changing.

scientific article

New molecular targets in non clear renal cell carcinoma: An overview of ongoing clinical trials.

scientific article published on 15 May 2015

New target therapies in advanced pancreatic cancer.

scientific article published on May 2006

Novel agents, combinations and sequences for the treatment of advanced renal cell carcinoma: When is the revolution coming?

scientific article published on March 2013

Novel perspectives for the treatment of gastric cancer: from a global approach to a personalized strategy.

scientific article published in May 2010

Novel small molecule EGFR inhibitors as candidate drugs in non-small cell lung cancer.

scientific article published on 21 May 2013

Novel therapeutic approaches to cancer patients with bone metastasis.

scientific article

Nuclear Factor-kB Tumor Expression Predicts Response and Survival in Irinotecan-Refractory Metastatic Colorectal Cancer Treated With Cetuximab-Irinotecan Therapy

article

Occult breast cancer: the uncommon presentation of a common disease

scientific article published on 13 February 2019

Off-target effects and clinical outcome in metastatic colorectal cancer patients receiving regorafenib: The TRIBUTE analysis

scientific article published on 05 April 2017

Oligometastatic gastric cancer: An emerging clinical entity with distinct therapeutic implications

scientific article published on 10 November 2018

Osteonecrosis of the Jaw in a Breast Cancer Patient Treated with Everolimus and a Single Dose of Zoledronic Acid

scientific article published on 22 March 2017

Out-of-pocket costs for cancer survivors between 5 and 10 years from diagnosis: an Italian population-based study

scientific article

Over-DI dissection may question the value of radiotherapy as a part of an adjuvant programme in high-risk radically resected gastric cancer patients.

scientific article published on March 2005

P-CHOP: cisplatin (P) added to the standard CHOP regimen as first-line treatment for aggressive non-Hodgkin lymphoma: a single-institution phase II study

scientific article

PD-1 blockade therapy in renal cell carcinoma: current studies and future promises.

scientific article

PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer.

scientific article published on 27 April 2009

Paclitaxel and epirubicin followed by cyclophosphamide, methotrexate and 5-fluorouracil for patients with stage IIIC breast cancer with ten or more involved axillary lymph nodes

scientific article

Pain and its treatment in hospitalized patients with metastatic cancer

scientific article published on 05 August 2003

Pancreatic cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

scientific article

Pancreatic cancer: progress in cancer therapy.

scientific article published on 19 March 2008

Panitumumab for the treatment of metastatic colorectal cancer: a review.

scientific article published on 07 August 2015

Panitumumab in combination with infusional oxaliplatin and oral capecitabine for conversion therapy in patients with colon cancer and advanced liver metastases ⬇️

scientific article published on July 18, 2013

Panitumumab versus cetuximab in patients with chemotherapy-refractory wild-type KRAS exon 2 metastatic colorectal cancer (ASPECCT): a randomised, multicentre, open-label, non-inferiority phase 3 study

scientific article (publication date: May 2014)

Panitumumab: the evidence for its use in the treatment of metastatic colorectal cancer

scientific article

Patient and caregiver needs in oncology. An Italian survey.

scientific article published on 13 June 2015

Patterns of recurrence of bronchioloalveolar cell carcinoma after surgical resection: a radiological, histological, and immunohistochemical study

scientific article published on 01 December 2003

Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells

scientific article published on 25 July 2013

Pegylated liposomal doxorubicin, 5-fluorouracil and cisplatin versus mitomycin-C, 5-fluorouracil and cisplatin for advanced gastric cancer: a randomized phase II trial

scientific article

Pemetrexed in combination with oxaliplatin as a first-line therapy for advanced gastric cancer: a multi-institutional phase II study

scientific article

Performance at Preoperative Stair-Climbing Test Is Associated With Prognosis After Pulmonary Resection in Stage I Non-Small Cell Lung Cancer

article published in 2012

Perioperative anemia and blood transfusions as prognostic factors in patients undergoing resection for non-small cell lung cancers

scientific article published on 01 September 2005

Personalized management of elderly patients with rectal cancer: Expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, and American College of Surgeons Com

scientific article published on 15 August 2018

Perspectives from American Society of Clinical Oncology: translational and clinical research highlights in breast and colorectal cancers.

scientific article published in October 2014

Pharmacogenetic profiling and clinical outcome of patients with advanced gastric cancer treated with palliative chemotherapy

scientific article published on 01 April 2006

Pharmacogenomics of cetuximab in metastatic colorectal carcinoma.

scientific article

Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer.

scientific article

Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study).

scientific article

Phase II study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study).

scientific article published on 22 September 2009

Phase II study of pharmacogenetic-tailored therapy in elderly colorectal cancer patients

scientific article published on 03 September 2011

Phase II study of sequential cisplatin plus 5-fluorouracil/leucovorin (5-FU/LV) followed by irinotecan plus 5-FU/LV followed by docetaxel plus 5-FU/LV in patients with metastatic gastric or gastro-oesophageal junction adenocarcinoma.

scientific article published on 17 March 2010

Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan-cetuximab

scientific article

Phosphorylated mTOR is associated to androgen receptor expression in early triple-negative breast cancer.

scientific article published on 22 June 2016

Position paper of the Italian Association of Medical Oncology on early palliative care in oncology practice (Simultaneous Care).

scientific article published on 19 December 2016

Post-surgical pyoderma gangrenosum of the breast: needs for early diagnosis and right therapy

scientific article published on 18 December 2018

Potential role and chronology of abnormal expression of the Deleted in Colon Cancer (DCC) and the p53 proteins in the development of gastric cancer

scientific article

Pre-operative treatment modalities in gastric cancer patients.

scientific article

Pre-treatment lactate dehydrogenase levels as predictor of efficacy of first-line bevacizumab-based therapy in metastatic colorectal cancer patients ⬇️

scientific article published on February 7, 2012

Pre-treatment neutrophil to lymphocyte ratio may be a useful tool in predicting survival in early triple negative breast cancer patients

scientific article published on 28 March 2015

Pre-treatment neutrophil-to-lymphocyte ratio may be associated with the outcome in patients treated with everolimus for metastatic renal cell carcinoma

scientific article published on 05 September 2013

Predictive and prognostic role of E-cadherin protein expression in patients with advanced gastric carcinomas treated with palliative chemotherapy.

scientific article published in May 2004

Predictive factors for sunitinib treatment response in advanced renal cell carcinoma: are we really making steps forward?

scientific article published on 01 February 2015

Present and future of personalized medicine in adult genitourinary tumors

scientific article published on January 2015

Present and future of tyrosine kinase inhibitors in renal cell carcinoma: analysis of hematologic toxicity.

scientific article published on August 2012

Professional failure: how do oncologists feel it?

scientific article published on 29 October 2011

Prognostic Role of PD-L1 Expression in Renal Cell Carcinoma. A Systematic Review and Meta-Analysis

scientific article published on 2 October 2015

Prognostic Role ofInterleukin-1βGene andInterleukin-1 Receptor AntagonistGene Polymorphisms in Patients With Advanced Gastric Cancer

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Prognostic Value for Incidental Antihypertensive Therapy With β-Blockers in Metastatic Colorectal Cancer.

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Prognostic analysis of E-cadherin gene promoter hypermethylation in patients with surgically resected, node-positive, diffuse gastric cancer.

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Prognostic and predictive factors in patients treated with chemotherapy for advanced urothelial cancer: where do we stand?

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Prognostic clinical factors in pretreated colorectal cancer patients receiving regorafenib: implications for clinical management

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Prognostic impact of mismatch repair genes germline defects in colorectal cancer patients: are all mutations equal?

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Prognostic impact of the cumulative dose and dose intensity of everolimus in patients with pancreatic neuroendocrine tumors.

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Prognostic models to predict survival in patients with advanced non-small cell lung cancer treated with first-line chemo- or targeted therapy

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Prognostic role of thymidylate synthase polymorphisms in gastric cancer patients treated with surgery and adjuvant chemotherapy

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Prognostic significance of host immune status in patients with late relapsing renal cell carcinoma treated with targeted therapy

scientific article published on 6 January 2015

Progress of molecular targeted therapies for advanced renal cell carcinoma.

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Prophylactic use of mTOR inhibitors and other immunosuppressive agents in heart transplant patients

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Prospective multicenter study of combined treatment with chemotherapy and radiotherapy in breast cancer women with the rare clinical scenario of ipsilateral supraclavicular node recurrence without distant metastases.

scientific article published on 30 January 2006

Prospective study of a molecular selection profile for RAS wild type colorectal cancer patients receiving irinotecan-cetuximab

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Protracted low doses of temozolomide for the treatment of patients with recurrent glioblastoma: A phase II study

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Raltitrexed plus oxaliplatin (TOMOX) as first-line chemotherapy for metastatic colorectal cancer. A phase II study of the Italian Group for the Study of Gastrointestinal Tract Carcinomas (GISCAD).

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Randomized Trial of Low-Dose Morphine Versus Weak Opioids in Moderate Cancer Pain

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Real-world study of everolimus in advanced progressive neuroendocrine tumors

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Recent aspects of sunitinib therapy in patients with metastatic clear-cell renal cell carcinoma: a systematic review of the literature

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Regorafenib for Patients with Metastatic Colorectal Cancer Who Progressed After Standard Therapy: Results of the Large, Single-Arm, Open-Label Phase IIIb CONSIGN Study

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Regorafenib plus modified FOLFOX6 as first-line treatment of metastatic colorectal cancer: A phase II trial.

scientific article published on 25 March 2015

Reply to O. Corli et al and M. Lucchesi et al

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Resected biliary tract cancers: A novel clinical–pathological score correlates with global outcome

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Resistance to EGFR inhibitors in non-small cell lung cancer: Clinical management and future perspectives.

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Risk of Hyponatraemia in Cancer Patients Treated with Targeted Therapies: A Systematic Review and Meta-Analysis of Clinical Trials

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Risk of gastrointestinal events with sorafenib, sunitinib and pazopanib in patients with solid tumors: a systematic review and meta-analysis of clinical trials

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Risk of pruritus in cancer patients treated with biological therapies: A systematic review and meta-analysis of clinical trials

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Risk of recurrence and conditional survival in complete responders treated with TKIs plus or less locoregional therapies for metastatic renal cell carcinoma

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Role and mechanisms of resistance of epidermal growth factor receptor antagonists in the treatment of colorectal cancer.

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Role of SIRT-3, p-mTOR and HIF-1α in Hepatocellular Carcinoma Patients Affected by Metabolic Dysfunctions and in Chronic Treatment with Metformin ⬇️

scientific article published on 26 March 2019

Role of STAT3 pathway in genitourinary tumors.

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Role of evaluating tumor‑infiltrating lymphocytes, programmed death‑1 ligand 1 and mismatch repair proteins expression in malignant mesothelioma

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Role of natural and adaptive immunity in renal cell carcinoma response to VEGFR-TKIs and mTOR inhibitor.

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Second-line angiogenesis inhibition in metastatic colorectal cancer patients: Straightforward or overcrowded?

scientific article published on 12 February 2016

Second-line treatments: moving towards an opportunity to improve survival in advanced gastric cancer?

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Selected gastrointestinal cancer presentations from the American Society of Clinical Oncology annual meeting 2013 in review: it is not about the destination, it is about the journey

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Selected news from the 2014 Genitourinary Cancers Symposium: translating novel strategies into clinical practice.

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Small renal masses in the era of personalized medicine: Tumor heterogeneity, growth kinetics, and risk of metastasis.

scientific article published on 12 May 2015

Social support networks and depression of women suffering from early-stage breast cancer: a case control study

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Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer

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Somatostatin analogs: is one better than other?

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Sorafenib does not improve efficacy of chemotherapy in advanced pancreatic cancer: A GISCAD randomized phase II study

scientific article published on 02 November 2013

Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells.

scientific article published on 23 March 2015

Speckle-tracking global longitudinal strain as an early predictor of cardiotoxicity in breast carcinoma.

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State of the art for cardiotoxicity due to chemotherapy and to targeted therapies: a literature review.

scientific article published on 21 March 2013

Stevens-Johnson syndrome during nivolumab treatment of NSCLC.

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Sunitinib, pazopanib or sorafenib for the treatment of patients with late relapsing metastatic renal cell carcinoma

scientific article published on 18 July 2014

Surgical resection does not improve survival in patients with renal metastases to the pancreas in the era of tyrosine kinase inhibitors

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Systemic Chemotherapy for Advanced Rare Pancreatic Histotype Tumors: A Retrospective Multicenter Analysis

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Targeted therapies and complete responses in first line treatment of metastatic renal cell carcinoma. A meta-analysis of published trials.

scientific article published on 11 September 2013

Temperament and Character Traits Associated with Health-Related Quality of Life in Cancer Patients ⬇️

scientific article published on May 1, 2012

The "angiogenetic ladder", step-wise angiogenesis inhibition in metastatic colorectal cancer.

scientific article published on 20 June 2014

The A.L.A.N. score identifies prognostic classes in advanced biliary cancer patients receiving first-line chemotherapy

scientific article published on 02 July 2019

The Italian Rare Pancreatic Exocrine Cancer Initiative

scientific article published on 09 April 2019

The MaiSON Project (Italy). Developing integration strategies for oncology organizations/associations through a participatory approach

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The Role of Aspirin as Antitumoral Agent for Heavily Pretreated Patients With Metastatic Colorectal Cancer Receiving Capecitabine Monotherapy

scientific article published on 04 August 2016

The Tower of Babel of liver metastases from colorectal cancer: are we ready for one language?

scientific article published on 08 September 2012

The challenge of targeted therapies for gastric cancer patients: the beginning of a long journey

scientific article published on 07 May 2014

The changes of lipid metabolism in advanced renal cell carcinoma patients treated with everolimus: a new pharmacodynamic marker?

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The clinical impact of teniposide in the treatment of elderly patients with small-cell lung cancer.

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The correlation between LDH serum levels and clinical outcome in advanced biliary tract cancer patients treated with first line chemotherapy.

scientific article published on 11 April 2016

The current and future role of the medical oncologist in the professional care for cancer patients: a position paper by the European Society for Medical Oncology (ESMO).

scientific article published on 13 December 2013

The distinctive molecular, pathological and clinical characteristics of BRAF-mutant colorectal tumors

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The evolving role of microsatellite instability in colorectal cancer: A review.

scientific article published on 27 October 2016

The impact of reproductive life on breast cancer risk in women with family history or BRCA mutation

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The management of pancreatic cancer. Current expert opinion and recommendations derived from the 8th World Congress on Gastrointestinal Cancer, Barcelona, 2006

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The prognostic impact of primary tumour location in patients with stage II and stage III colon cancer receiving adjuvant therapy. A GISCAD analysis from three large randomised trials

scientific article published on 21 February 2019

The prognostic role of hemoglobin levels in patients undergoing concurrent chemo-radiation for anal cancer.

scientific article published on 2 May 2018

The role of HER-3 expression in the prediction of clinical outcome for advanced colorectal cancer patients receiving irinotecan and cetuximab.

scientific article published on 6 January 2011

The role of LDH serum levels in predicting global outcome in HCC patients treated with sorafenib: implications for clinical management

scientific article published on 20 February 2014

The role of LDH serum levels in predicting global outcome in HCC patients undergoing TACE: implications for clinical management

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The role of micro-RNAs in hepatocellular carcinoma: from molecular biology to treatment.

scientific article published on 19 May 2014

The role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild-type colorectal cancer patients receiving irinotecan/cetuximab.

scientific article published on 20 June 2017

The route to personalized medicine in bladder cancer: where do we stand?

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The timing of surgery for resectable metachronous liver metastases from colorectal cancer: Better sooner than later? A retrospective analysis

scientific article published on 21 August 2010

The tumor-targeting immunocytokine F16-IL2 in combination with doxorubicin: dose escalation in patients with advanced solid tumors and expansion into patients with metastatic breast cancer.

scientific article published on January 2015

The value of lactate dehydrogenase serum levels as a prognostic and predictive factor for advanced pancreatic cancer patients receiving sorafenib.

scientific article published on 10 September 2015

Therapeutic decisions and treatment with sorafenib in hepatocellular carcinoma: final analysis of GIDEON study in Italy

scientific article published in May 2015

Three drugs vs two drugs first-line chemotherapy regimen in advanced gastric cancer patients: a retrospective analysis.

scientific article published on December 2015

Thymic neoplasms: an update on the use of chemotherapy and new targeted therapies. A literature review.

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Thymidylate synthase protein expression in colorectal cancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil

scientific article published on December 2002

To resect or not to resect: The hamletic dilemma of primary tumor resection in patients with asymptomatic stage IV colorectal cancer

scientific article published on 11 October 2018

Toll like receptors and pancreatic diseases: From a pathogenetic mechanism to a therapeutic target.

scientific article published on 11 April 2015

Toward molecularly selected chemotherapy for advanced gastric cancer: state of the art and future perspectives.

scientific article published on 20 May 2009

Tracking the 2015 Gastrointestinal Cancers Symposium: bridging cancer biology to clinical gastrointestinal oncology

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Trans-arterial chemo-embolization (TACE), with either lipiodol (traditional TACE) or drug-eluting microspheres (precision TACE, pTACE) in the treatment of hepatocellular carcinoma: efficacy and safety results from a large mono-institutional analysis

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Transient sunitinib resistance in gastrointestinal stromal tumors

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Translational challenges from the 2014 Gastrointestinal Cancers Symposium: toward a true tailored therapy through effective research

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Treatment of metastatic colorectal cancer with monoclonal antibody to vascular endothelial growth factor: does the metastatic site make the difference?

scientific article published on 01 September 2003

Treatment of pancreatic cancer. Actuality and perspective

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Treatment-related fatigue with sorafenib, sunitinib and pazopanib in patients with advanced solid tumors: an up-to-date review and meta-analysis of clinical trials.

scientific article published on 07 February 2014

Tumor VEGF expression correlates with tumor stage and identifies prognostically different groups in patients with clear cell renal cell carcinoma

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Tumor angiogenesis genotyping and efficacy of first-line chemotherapy in metastatic gastric cancer patients

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Tumor response and symptom palliation from RAINBOW, a phase 3 trial of ramucirumab plus paclitaxel in previously treated advanced gastric cancer

scientific article published on 03 December 2020

VEGF and VEGFR genotyping in the prediction of clinical outcome for HCC patients receiving sorafenib: the ALICE-1 study

scientific article published on 20 February 2014

Validation of a Simple Scoring System to Predict Sorafenib Effectiveness in Patients with Hepatocellular Carcinoma.

scientific article published on 3 August 2017

Venous thromboembolism predicts poor prognosis in irresectable pancreatic cancer patients

scientific article published on 28 July 2007

Weekly gemcitabine and cisplatin chemotherapy: a well-tolerated but ineffective chemotherapeutic regimen in advanced pancreatic cancer patients. A report from the Italian Group for the Study of Digestive Tract Cancer (GISCAD).

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Weekly gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase II study

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Weekly oxaliplatin, 5-fluorouracil and folinic acid (OXALF) as first-line chemotherapy for elderly patients with advanced gastric cancer: results of a phase II trial

scientific article published on 10 May 2006

What Medical Oncologist Residents Think about the Italian Speciality Schools: A Survey of the Italian Association of Medical Oncology (AIOM) on Educational, Clinical and Research Activities

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Women and lung cancer: clinical and molecular profiling as a determinate for treatment decisions: a literature review.

scientific article published on 22 August 2008

eNOS polymorphisms and clinical outcome in advanced HCC patients receiving sorafenib: final results of the ePHAS study

scientific article published on 04 April 2016

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