List of works - Michael A. Puskarich

A 12-hospital prospective evaluation of a clinical decision support prognostic algorithm based on logistic regression as a form of machine learning to facilitate decision making for patients with suspected COVID-19

scientific article published in 2022

A decision tree incorporating biomarkers and patient characteristics estimates mortality risk for adults with septic shock

scientific article published on 27 August 2014

A fast, resource efficient, and reliable rule-based system for COVID-19 symptom identification

scientific article published in July 2021

Air Ambulance Delivery and Administration of Four-factor Prothrombin Complex Concentrate Is Feasible and Decreases Time to Anticoagulation Reversal

scientific article published on 27 October 2017

An Emergency Department Validation of the SEP-3 Sepsis and Septic Shock Definitions and Comparison With 1992 Consensus Definitions.

scientific article published on 2 March 2017

Association Between Early Hyperoxia Exposure After Resuscitation from Cardiac Arrest and Neurological Disability: A Prospective Multi-Center Protocol-Directed Cohort Study.

scientific article published in February 2018

Association Between Elevated Mean Arterial Blood Pressure and Neurologic Outcome After Resuscitation From Cardiac Arrest: Results From a Multicenter Prospective Cohort Study

scientific article published on 01 January 2019

Association between persistent tachycardia and tachypnea and in-hospital mortality among non-hypotensive emergency department patients admitted to the hospital

scientific article published on 30 March 2017

Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol

scientific article

Big data to the rescue of systemic inflammatory response syndrome: is electronic data mining the way of the future?

scientific article published on December 2016

Biomarkers of endothelial cell activation in early sepsis

scientific article published on May 2013

Can Vasopressors Safely Be Administered Through Peripheral Intravenous Catheters Compared With Central Venous Catheters?

scientific article published on 23 July 2015

Characteristics and outcomes of patients with vasoplegic versus tissue dysoxic septic shock

scientific article published on July 2013

Circulating Complement C3-Alpha Chain Levels Predict Survival of Septic Shock Patients

scientific article published on 26 December 2019

Clearing lactate is clearly better…but how much?*.

scientific article published in September 2014

Clinical predictors of early death from sepsis

scientific article published on 23 June 2017

Decompensation to shock: what is the risk?

scientific article published on 01 May 2015

Development of a Clinical Teaching Evaluation and Feedback Tool for Faculty

article

Development of a Simple Sequential Organ Failure Assessment Score for Risk Assessment of Emergency Department Patients With Sepsis.

scientific article published in January 2017

Early alterations in platelet mitochondrial function are associated with survival and organ failure in patients with septic shock

scientific article

Effect of Levocarnitine vs Placebo as an Adjunctive Treatment for Septic Shock: The Rapid Administration of Carnitine in Sepsis (RACE) Randomized Clinical Trial

scientific article published on 07 December 2018

Effect of glucose-insulin-potassium infusion on mortality in critical care settings: a systematic review and meta-analysis.

scientific article

Effect of glucose–insulin–potassium infusion on mortality in critically ill patients: a systematic review and meta-analysis.

scientific article published on 13 March 2009

Emergency Department Sepsis Care: Could It Matter Who Is in the Ambulance?

scientific article published on 01 December 2018

Emergency management of severe sepsis and septic shock.

scientific article published on August 2012

Erratum: This Article Corrects: "Development of a Clinical Teaching Evaluation and Feedback Tool for Emergency Medicine Faculty"

scientific article published on 20 August 2019

Explicitly targeting explicit sepsis: fair metrics for quality assessment*

scientific article published on 01 March 2014

Inhaled nitric oxide to control platelet hyper-reactivity in patients with acute submassive pulmonary embolism

scientific article published on 12 January 2020

Inhaled nitric oxide to treat intermediate risk pulmonary embolism: A multicenter randomized controlled trial

scientific article published on 08 January 2019

Is lactate the "Holy Grail" of biomarkers for sepsis prognosis?

scientific article published in May 2009

Lactate Clearance in Septic Shock Is Not a Surrogate for Improved Microcirculatory Flow

scientific article published on 30 January 2016

Lactate Levels in Patients Receiving Hemodialysis: A Confounder in the Assessment of Infected Patients

scientific article published on 23 November 2017

Metabolomics as a Driver in Advancing Precision Medicine in Sepsis.

scientific article

Outcomes of patients undergoing early sepsis resuscitation for cryptic shock compared with overt shock.

scientific article

Partial pressure of arterial carbon dioxide after resuscitation from cardiac arrest and neurological outcome: A prospective multi-center protocol-directed cohort study

scientific article published on 16 November 2018

Pharmacometabolomics of l-carnitine treatment response phenotypes in patients with septic shock.

scientific article

Phosphatidylserine expressing platelet microparticle levels at hospital presentation are decreased in sepsis non-survivors and correlate with thrombocytopenia

scientific article published on 28 June 2018

Plasma Glycoproteomics Reveals Sepsis Outcomes Linked to Distinct Proteins in Common Pathways

scientific article

Plasma Levels of Mitochondrial DNA in Patients Presenting to the Emergency Department With Sepsis ⬇️

scientific article published on October 1, 2012

Plasma syndecan-1 levels identify a cohort of patients with severe sepsis at high risk for intubation after large-volume intravenous fluid resuscitation.

scientific article published on 7 July 2016

Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism

scientific article

Predicting 30-day return hospital admissions in patients with COVID-19 discharged from the emergency department: A national retrospective cohort study

scientific article published on 29 December 2021

Prehospital treatment of sepsis: what really makes the "golden hour" golden?

scientific article

Priorities to Overcome Barriers Impacting Data Science Application in Emergency Care Research

scientific article published on 16 August 2018

Prognosis of emergency department patients with suspected infection and intermediate lactate levels: a systematic review.

scientific article published on 04 January 2014

Prognostic Value and Agreement of Achieving Lactate Clearance or Central Venous Oxygen Saturation Goals During Early Sepsis Resuscitation ⬇️

scientific article published on March 1, 2012

Prognostic value of incremental lactate elevations in emergency department patients with suspected infection

scientific article published on August 2012

Randomized trial of inhaled nitric oxide to treat acute pulmonary embolism: The iNOPE trial

scientific article published on 27 January 2017

Rapid, Reproducible, Quantifiable NMR Metabolomics: Methanol and Methanol: Chloroform Precipitation for Removal of Macromolecules in Serum and Whole Blood

scientific article published on 14 December 2018

Sepsis-induced tissue hypoperfusion.

scientific article published on October 2009

Sepsis-induced tissue hypoperfusion.

scientific article published on March 2011

Septic Shock Non-Survivors have Persistently Elevated Acylcarnitines Following Carnitine Supplementation

scientific article published on 20 September 2017

Sequential Organ Failure Assessment Component Score Prediction of In-hospital Mortality From Sepsis

scientific article published on 30 August 2018

Systematic Molecular Phenotyping: A Path Toward Precision Emergency Medicine?

scientific article published on 11 June 2016

The Challenge and the Promise of Studying Mitochondrial Dysfunction in Humans with Sepsis

scientific article published in November 2015

The Impact of Timing of Antibiotics on Outcomes in Severe Sepsis and Septic Shock: A Systematic Review and Meta-Analysis

scientific article

The Impact of the Sepsis-3 Septic Shock Definition on Previously Defined Septic Shock Patients

scientific article published on 24 May 2017

The Surviving Sepsis Campaign guidelines 2012: update for emergency physicians

scientific article published on 23 September 2013

The association of near infrared spectroscopy-derived StO2 measurements and biomarkers of endothelial activation in sepsis

scientific article

The authors reply

scientific article published on 01 March 2018

The authors reply

scientific article published on 01 October 2016

The authors reply

scientific article published in April 2016

The authors reply

scientific article published in October 2016

The authors reply

The curious case of the missing sepsis patients

scientific article published on 01 January 2015

The effect of early quantitative resuscitation on organ function in survivors of septic shock

scientific article

The effect of etomidate on mortality in sepsis remains unclear

scientific article published in June 2013

The effect of liver disease on lactate normalization in severe sepsis and septic shock: a cohort study

scientific article published on 28 December 2015

Untargeted Metabolomics Differentiates l-Carnitine Treated Septic Shock 1-Year Survivors and Nonsurvivors

scientific article published on 01 April 2019

Use of Emergency Medicine Milestones as Items on End-of-Shift Evaluations Results in Overestimates of Residents' Proficiency Level

scientific article published on June 2015

Utilizing Geographic Information Systems to Identify Clusters of Severe Sepsis Patients Presenting in the Out-of-Hospital Environment

scientific article

Validation of a 5-item tool to measure patient assessment of clinician compassion in the emergency department

scientific article published on 04 November 2019

What Is the Prognosis of Nontraumatic Hypotension and Shock in the Out-of-Hospital and Emergency Department Setting?

scientific article published on 29 July 2015

Whole Blood Reveals More Metabolic Detail of the Human Metabolome than Serum as Measured by 1H-NMR Spectroscopy: Implications for Sepsis Metabolomics.

scientific article

Whole blood lactate kinetics in patients undergoing quantitative resuscitation for septic shock.

scientific article published on 11 March 2011

List of works by Michael A. Puskarich

A 12-hospital prospective evaluation of a clinical decision support prognostic algorithm based on logistic regression as a form of machine learning to facilitate decision making for patients with suspected COVID-19

A decision tree incorporating biomarkers and patient characteristics estimates mortality risk for adults with septic shock

A fast, resource efficient, and reliable rule-based system for COVID-19 symptom identification

Air Ambulance Delivery and Administration of Four-factor Prothrombin Complex Concentrate Is Feasible and Decreases Time to Anticoagulation Reversal

An Emergency Department Validation of the SEP-3 Sepsis and Septic Shock Definitions and Comparison With 1992 Consensus Definitions.

Association Between Early Hyperoxia Exposure After Resuscitation from Cardiac Arrest and Neurological Disability: A Prospective Multi-Center Protocol-Directed Cohort Study.

Association Between Elevated Mean Arterial Blood Pressure and Neurologic Outcome After Resuscitation From Cardiac Arrest: Results From a Multicenter Prospective Cohort Study

Association between persistent tachycardia and tachypnea and in-hospital mortality among non-hypotensive emergency department patients admitted to the hospital

Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol

Big data to the rescue of systemic inflammatory response syndrome: is electronic data mining the way of the future?

Biomarkers of endothelial cell activation in early sepsis

Can Vasopressors Safely Be Administered Through Peripheral Intravenous Catheters Compared With Central Venous Catheters?

Characteristics and outcomes of patients with vasoplegic versus tissue dysoxic septic shock

Circulating Complement C3-Alpha Chain Levels Predict Survival of Septic Shock Patients

Clearing lactate is clearly better…but how much?*.

Clinical predictors of early death from sepsis

Decompensation to shock: what is the risk?

Development of a Clinical Teaching Evaluation and Feedback Tool for Faculty

Development of a Simple Sequential Organ Failure Assessment Score for Risk Assessment of Emergency Department Patients With Sepsis.

Early alterations in platelet mitochondrial function are associated with survival and organ failure in patients with septic shock

Effect of Levocarnitine vs Placebo as an Adjunctive Treatment for Septic Shock: The Rapid Administration of Carnitine in Sepsis (RACE) Randomized Clinical Trial

Effect of glucose-insulin-potassium infusion on mortality in critical care settings: a systematic review and meta-analysis.

Effect of glucose–insulin–potassium infusion on mortality in critically ill patients: a systematic review and meta-analysis.

Emergency Department Sepsis Care: Could It Matter Who Is in the Ambulance?

Emergency management of severe sepsis and septic shock.

Erratum: This Article Corrects: "Development of a Clinical Teaching Evaluation and Feedback Tool for Emergency Medicine Faculty"

Explicitly targeting explicit sepsis: fair metrics for quality assessment*

Inhaled nitric oxide to control platelet hyper-reactivity in patients with acute submassive pulmonary embolism

Inhaled nitric oxide to treat intermediate risk pulmonary embolism: A multicenter randomized controlled trial

Is lactate the "Holy Grail" of biomarkers for sepsis prognosis?

Lactate Clearance in Septic Shock Is Not a Surrogate for Improved Microcirculatory Flow

Lactate Levels in Patients Receiving Hemodialysis: A Confounder in the Assessment of Infected Patients

Metabolomics as a Driver in Advancing Precision Medicine in Sepsis.

Outcomes of patients undergoing early sepsis resuscitation for cryptic shock compared with overt shock.

Partial pressure of arterial carbon dioxide after resuscitation from cardiac arrest and neurological outcome: A prospective multi-center protocol-directed cohort study

Pharmacometabolomics of l-carnitine treatment response phenotypes in patients with septic shock.

Phosphatidylserine expressing platelet microparticle levels at hospital presentation are decreased in sepsis non-survivors and correlate with thrombocytopenia

Plasma Glycoproteomics Reveals Sepsis Outcomes Linked to Distinct Proteins in Common Pathways

Plasma Levels of Mitochondrial DNA in Patients Presenting to the Emergency Department With Sepsis ⬇️

Plasma syndecan-1 levels identify a cohort of patients with severe sepsis at high risk for intubation after large-volume intravenous fluid resuscitation.

Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism

Predicting 30-day return hospital admissions in patients with COVID-19 discharged from the emergency department: A national retrospective cohort study

Prehospital treatment of sepsis: what really makes the "golden hour" golden?

Priorities to Overcome Barriers Impacting Data Science Application in Emergency Care Research

Prognosis of emergency department patients with suspected infection and intermediate lactate levels: a systematic review.

Prognostic Value and Agreement of Achieving Lactate Clearance or Central Venous Oxygen Saturation Goals During Early Sepsis Resuscitation ⬇️

Prognostic value of incremental lactate elevations in emergency department patients with suspected infection

Randomized trial of inhaled nitric oxide to treat acute pulmonary embolism: The iNOPE trial

Rapid, Reproducible, Quantifiable NMR Metabolomics: Methanol and Methanol: Chloroform Precipitation for Removal of Macromolecules in Serum and Whole Blood

Sepsis-induced tissue hypoperfusion.

Sepsis-induced tissue hypoperfusion.

Septic Shock Non-Survivors have Persistently Elevated Acylcarnitines Following Carnitine Supplementation

Sequential Organ Failure Assessment Component Score Prediction of In-hospital Mortality From Sepsis

Systematic Molecular Phenotyping: A Path Toward Precision Emergency Medicine?

The Challenge and the Promise of Studying Mitochondrial Dysfunction in Humans with Sepsis

The Impact of Timing of Antibiotics on Outcomes in Severe Sepsis and Septic Shock: A Systematic Review and Meta-Analysis

The Impact of the Sepsis-3 Septic Shock Definition on Previously Defined Septic Shock Patients

The Surviving Sepsis Campaign guidelines 2012: update for emergency physicians

The association of near infrared spectroscopy-derived StO2 measurements and biomarkers of endothelial activation in sepsis

The authors reply

The authors reply

The authors reply

The authors reply

The authors reply

The authors reply

The authors reply

The curious case of the missing sepsis patients

The effect of early quantitative resuscitation on organ function in survivors of septic shock

The effect of etomidate on mortality in sepsis remains unclear

The effect of liver disease on lactate normalization in severe sepsis and septic shock: a cohort study

Untargeted Metabolomics Differentiates l-Carnitine Treated Septic Shock 1-Year Survivors and Nonsurvivors

Use of Emergency Medicine Milestones as Items on End-of-Shift Evaluations Results in Overestimates of Residents' Proficiency Level

Utilizing Geographic Information Systems to Identify Clusters of Severe Sepsis Patients Presenting in the Out-of-Hospital Environment

Validation of a 5-item tool to measure patient assessment of clinician compassion in the emergency department

What Is the Prognosis of Nontraumatic Hypotension and Shock in the Out-of-Hospital and Emergency Department Setting?

Whole Blood Reveals More Metabolic Detail of the Human Metabolome than Serum as Measured by 1H-NMR Spectroscopy: Implications for Sepsis Metabolomics.

Whole blood lactate kinetics in patients undergoing quantitative resuscitation for septic shock.