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List of works by Andrew G Brooks

A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells

scientific article

A Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition

scientific article

A Protective Vaccine Delivery System for In Vivo T Cell Stimulation Using Nanoengineered Polymer Hydrogel Capsules

article

A bird's eye view of NK cell receptor interactions with their MHC class I ligands

scientific article published on September 2015

A conserved energetic footprint underpins recognition of Human Leukocyte Antigen-E by two distinct αβ T cell receptors

scientific article published on 25 September 2017

A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection

scientific article published on May 2007

A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties

scientific article

A single amino acid substitution in the hemagglutinin of H3N2 subtype influenza A viruses is associated with resistance to the long pentraxin PTX3 and enhanced virulence in mice

scientific article published on 4 December 2013

A structural basis for antigen presentation by the MHC class Ib molecule, Qa-1b

scientific article

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity

scientific article

A structural perspective on MHC class Ib molecules in adaptive immunity

scientific article published on 21 July 2006

Activating killer-cell immunoglobulin-like receptor haplotype influences clinical outcome following HLA-matched sibling haematopoietic stem cell transplantation

scientific article published on 25 June 2018

Addition of glycosylation to influenza A virus hemagglutinin modulates antibody-mediated recognition of H1N1 2009 pandemic viruses

scientific article

Age-associated cross-reactive antibody-dependent cellular cytotoxicity toward 2009 pandemic influenza A virus subtype H1N1.

scientific article

Allelic polymorphism in the T cell receptor and its impact on immune responses

scientific article

Analysis of pigtail macaque major histocompatibility complex class I molecules presenting immunodominant simian immunodeficiency virus epitopes

scientific article published on January 2005

Anti-HIV antibody-dependent activation of NK cells impairs NKp46 expression

scientific article published on 6 December 2013

Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates

scientific article published on 14 January 2015

Antigen presentation and assembly by mouse I-Ak class II molecules in human APC containing deleted or mutated HLA DM genes.

scientific article published on December 1994

Antiviral activity of the long chain pentraxin PTX3 against influenza viruses

scientific article

Application of CD27 as a marker for distinguishing human NK cell subsets.

scientific article published on 7 March 2008

Blood-stage Plasmodium berghei infection generates a potent, specific CD8+ T-cell response despite residence largely in cells lacking MHC I processing machinery

scientific article published on 13 October 2011

CD8+ T-cell maturation following lung transplantation: The differential impact of CMV and acute rejection

scientific article published on 08 August 2007

CD8<sup>+</sup> T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

scientific article published on 18 May 2021

CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence

scientific article

Cell-surface receptors on macrophages and dendritic cells for attachment and entry of influenza virus

scientific article

Changes in Gut Microbiota Prior to Influenza A Virus Infection Do Not Affect Immune Responses in Pups or Juvenile Mice

article

Class II-restricted presentation of a hen egg lysozyme determinant derived from endogenous antigen sequestered in the cytoplasm or endoplasmic reticulum of the antigen presenting cells

scientific article published on May 1993

Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection

article

Comparison of influenza and SIV specific CD8 T cell responses in macaques

scientific article

Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3

scientific article

Contribution of Thy1+ NK cells to protective IFN-γ production during Salmonella typhimurium infections

scientific article published on 23 January 2013

Correlation between sialic acid expression and infection of murine macrophages by different strains of influenza virus ⬇️

scientific article published on October 23, 2010

Critical role of airway macrophages in modulating disease severity during influenza virus infection of mice

scientific article

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

scientific article published on 6 April 2009

Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies

scientific article

Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface

scientific article

Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand

scientific article

Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2

scientific article

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

scholarly article

Cytomegalovirus replication is associated with enrichment of distinct γδ T cell subsets following lung transplantation: A novel therapeutic approach?

scientific article published on 26 August 2020

DC-SIGN and L-SIGN Are Attachment Factors That Promote Infection of Target Cells by Human Metapneumovirus in the Presence or Absence of Cellular Glycosaminoglycans

scientific article published on 22 June 2016

DEC-205 is a cell surface receptor for CpG oligonucleotides

scientific article

DX5/CD49b-Positive T Cells Are Not Synonymous with CD1d-Dependent NKT Cells

scientific article published on 21 September 2005

Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells.

scientific article

Depletion of Gr-1+, but not Ly6G+, immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infection

scientific article published on 9 June 2010

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells

scientific article published on 14 August 2011

Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

scientific article

Distinct APC subtypes drive spatially segregated CD4+ and CD8+ T-cell effector activity during skin infection with HSV-1

scientific article (publication date: August 2014)

Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus

scientific article

Diverse roles of non-diverse molecules: MHC class Ib molecules in host defense and control of autoimmunity

scientific article

Downregulation of MHC Class I Expression by Influenza A and B Viruses

scientific article published on 29 May 2019

Endocytic function is critical for influenza A virus infection via DC-SIGN and L-SIGN.

scientific article

Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection

scientific article published on 13 November 2015

Enrichment of cytomegalovirus-induced NKG2C+ Natural Killer cells in the lung allograft

scientific article published on 01 August 2019

Erratum for O'Connor et al., Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

scientific article published on July 2015

Glycosylation of the hemagglutinin modulates the sensitivity of H3N2 influenza viruses to innate proteins in airway secretions and virulence in mice

scientific article published on 24 February 2011

Gr-1+ cells, but not neutrophils, limit virus replication and lesion development following flank infection of mice with herpes simplex virus type-1.

scientific article published in November 2010

HLA peptide length preferences control CD8+ T cell responses

scientific article

HLA-E is the ligand for the natural killer cell CD94/NKG2 receptors

scientific article published on 01 September 1998

HLA-E-restricted CD8+ T Lymphocytes Efficiently Control Mycobacterium tuberculosis and HIV-1 Coinfection

scientific article published on 01 April 2020

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

scientific article

Herpes simplex virus-specific CD8+ T cells can clear established lytic infections from skin and nerves and can partially limit the early spread of virus after cutaneous inoculation

scientific article published in January 2004

Host Cell Restriction Factors that Limit Influenza A Infection.

scientific article published on 7 December 2017

How opposites attract ⬇️

scientific article published on December 7, 2010

Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines

scientific article

IFITM3 and type I interferons are important for the control of influenza A virus replication in murine macrophages

scientific article published on 05 November 2019

IL-18, but not IL-12, regulates NK cell activity following intranasal herpes simplex virus type 1 infection

scientific article

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex

scientific article published on September 2002

Infection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle

scientific article

Influenza viruses differ in ability to infect macrophages and to induce a local inflammatory response following intraperitoneal injection of mice

scientific article

Inhibition of lectin‐mediated innate host defences in vivo modulates disease severity during influenza virus infection ⬇️

scientific article published on October 12, 2010

Intrathymic NKT cell development is blocked by the presence of alpha-galactosylceramide

scientific article published on July 2003

Killer Ig-Like Receptor Ligand Mismatch Directs NK Cell Expansion In Vitro

scientific article published on 11 September 2009

Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition

scientific article published on 4 April 2016

Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B

scientific article

Killing kinetics of simian immunodeficiency virus-specific CD8+ T cells: implications for HIV vaccine strategies

scientific article published in October 2007

Limited Internodal Migration of T Follicular Helper Cells after Peripheral Infection with Herpes Simplex Virus-1.

scientific article published on 9 October 2015

Loss of a single N-linked glycan from the hemagglutinin of influenza virus is associated with resistance to collectins and increased virulence in mice

scientific article

MHC class I allele frequencies in pigtail macaques of diverse origin.

scientific article

MHC class Ib-restricted CD8 T cells differ in dependence on CD4 T cell help and CD28 costimulation over the course of mouse polyomavirus infection

scientific article published on 5 March 2012

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

scientific article published on 20 February 2017

Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity

scientific article

N-Linked Glycosylation Facilitates Sialic Acid-Independent Attachment and Entry of Influenza A Viruses into Cells Expressing DC-SIGN or L-SIGN ⬇️

scientific article published on December 29, 2010

NK cells contribute to the early clearance of HSV-1 from the lung but cannot control replication in the central nervous system following intranasal infection

scientific article published in April 2006

NK cells promote peritoneal xenograft rejection through an IFN-gamma-dependent mechanism

scientific article published on November 2006

Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells.

scientific article published on May 2017

Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion

scientific article

Natural Killer Cell Activation in the Lung Allograft Early Posttransplantation

scientific article published on 01 March 2010

Natural killer cell recognition of HLA class I molecules.

scientific article

Neutralizing inhibitors in the airways of naïve ferrets do not play a major role in modulating the virulence of H3 subtype influenza A viruses

scientific article

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

article

Neutrophils sustain effective CD8+ T‐cell responses in the respiratory tract following influenza infection ⬇️

scientific article published on April 12, 2011

Non-classical MHC Class I molecules regulating natural killer cell function.

scientific article published on March 2013

Pandemic H1N1 influenza A viruses are resistant to the antiviral activities of innate immune proteins of the collectin and pentraxin superfamilies

scientific article

Pattern recognition receptor immunomodulation of innate immunity as a strategy to limit the impact of influenza virus.

scientific article published on 3 November 2016

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

scientific article published on 4 March 2015

Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim

scientific article

Persistent expression of CD94/NKG2 receptors by virus-specific CD8 T cells is initiated by TCR-mediated signals

scientific article published on 9 August 2004

Polymorphism in human cytomegalovirus UL40 impacts on recognition of human leukocyte antigen-E (HLA-E) by natural killer cells.

scientific article published on 18 January 2013

Prime–boost immunization generates a high frequency, high-avidity CD8+ cytotoxic T lymphocyte population ⬇️

scientific article published on January 1, 2002

Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1.

scientific article

Protection afforded by live attenuated SIV is associated with rapid killing kinetics of CTLs

scientific article published in December 2008

Receptor specificity of the influenza virus hemagglutinin modulates sensitivity to soluble collectins of the innate immune system and virulence in mice ⬇️

scientific article published on March 21, 2011

Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis

scientific article

Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.

scientific article published on 6 July 2016

Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells.

scientific article published on 11 November 2012

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

scientific article

Reconstitution of Bacterial Expressed Human CD94: The Importance of the Stem Region for Dimer Formation

scientific article published on 01 March 2000

Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

scientific article published on June 2017

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

scientific article

Responses of mouse airway epithelial cells and alveolar macrophages to virulent and avirulent strains of influenza A virus

scientific article published in April 2011

Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses

scientific article

Soluble host defense lectins in innate immunity to influenza virus

scientific article

Spatiotemporally Distinct Interactions with Dendritic Cell Subsets Facilitates CD4+ and CD8+ T Cell Activation to Localized Viral Infection

scientific article published on 17 August 2015

Specific sites of N-linked glycosylation on the hemagglutinin of H1N1 subtype influenza A virus determine sensitivity to inhibitors of the innate immune system and virulence in mice

scientific article published on 18 July 2011

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C

scientific article published in 2021

Structure of killer cell immunoglobulin-like receptors and their recognition of the class I MHC molecules.

scientific article

Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors

scientific article

T cell allorecognition via molecular mimicry

scientific article

T-cell grit: large clonal expansions of virus-specific CD8+ T cells can dominate in the peripheral circulation for at least 18 years

scientific article

Targeting of a natural killer cell receptor family by a viral immunoevasin

scientific article

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance

scientific article

The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus

scientific article

The Ly49 natural killer cell receptors: a versatile tool for viral self-discrimination

scientific article published on 14 January 2014

The Presence of HLA-E-Restricted, CMV-Specific CD8+ T Cells in the Blood of Lung Transplant Recipients Correlates with Chronic Allograft Rejection

scientific article published on 24 August 2015

The Structure and Stability of the Monomorphic HLA-G Are Influenced by the Nature of the Bound Peptide

scientific article

The Structure of the Cytomegalovirus-Encoded m04 Glycoprotein, a Prototypical Member of the m02 Family of Immunoevasins

scientific article

The complex existence of γδ T cells following transplantation: the good, the bad and the simply confusing

scientific article published on 17 September 2019

The fate of influenza A virus after infection of human macrophages and dendritic cells ⬇️

scientific article published on August 15, 2012

The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition

scientific article

The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope

scientific article

The macrophage galactose-type lectin can function as an attachment and entry receptor for influenza virus

scientific article

The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity.

scientific article

The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule

scientific article published on 30 August 2017

The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function

scientific article published on 13 May 2020

The pigtail macaque MHC class I allele Mane-A*10 presents an immundominant SIV Gag epitope: identification, tetramer development and implications of immune escape and reversion.

scientific article

The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody

scientific article

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state

scientific article

The role of neutrophils during mild and severe influenza virus infections of mice

scientific article

The role of neutrophils in the upper and lower respiratory tract during influenza virus infection of mice

scientific article published on August 2008

The shaping of T cell receptor recognition by self-tolerance

scientific article

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization

scientific article

The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.

scientific article

Truncated HLA-G isoforms are retained in the endoplasmic reticulum and insufficiently provide HLA-E ligands

scientific article published in March 2004

Unique Transcriptional Architecture in Airway Epithelial Cells and Macrophages Shapes Distinct Responses following Influenza Virus Infection Ex Vivo

scientific article published on 05 March 2019

Virus infection expands a biased subset of T cells that bind tetrameric class I peptide complexes.

scientific article published in June 2003

V 2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen

scientific article

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