List of works by Akiyoshi Nakayama

A common variant of organic anion transporter 4 (OAT4/SLC22A11) gene is associated with renal underexcretion type gout

scientific article

ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload

scientific article published on 20 January 2014

ABCG2 dysfunction increases serum uric acid by decreased intestinal urate excretion

article

ABCG2 dysfunction increases the risk of renal overload hyperuricemia

scientific article published in January 2014

ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans

scientific article published on 01 December 2011

ABCG2/BCRP dysfunction as a major cause of gout

scientific article published in December 2011

Association Between Serum Uric Acid Levels/Hyperuricemia and Hypertension Among 85,286 Japanese Workers

scientific article

Carrier frequency of the GJB2 mutations that cause hereditary hearing loss in the Japanese population

scientific article

Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population

scientific article published in November 2009

Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

scientific article published on January 2013

Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors

scientific article published on 09 June 2014

Common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility

scientific article published on 29 August 2013

Common variant of ALPK1 is not associated with gout: a replication study.

scientific article

Common variant of BCAS3 is associated with gout risk in Japanese population: the first replication study after gout GWAS in Han Chinese.

scientific article

Common variant of PDZ domain containing 1 (PDZK1) gene is associated with gout susceptibility: A replication study and meta-analysis in Japanese population.

scientific article published on 30 July 2016

Common variant of PDZK1, adaptor protein gene of urate transporters, is not associated with gout

scientific article published on 01 November 2014

Common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility

scientific article

Common variants of a urate-associated gene LRP2 are not associated with gout susceptibility.

scientific article published on 24 December 2013

Common variants of cGKII/PRKG2 are not associated with gout susceptibility

scientific article published in June 2014

Ethnic differences in ATP-binding cassette transporter, sub-family G, member 2 (ABCG2/BCRP): genotype combinations and estimated functions

scientific article

Expression of a human NPT1/SLC17A1 missense variant which increases urate export

scientific article published on December 2016

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

scientific article published on 29 November 2016

Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes

scientific article published on 2 February 2015

Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout

scientific article published on 8 July 2019

Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals

scientific article published on 08 April 2019

Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2.

scientific article published on 30 August 2016

Identification of ABCG2 dysfunction as a major factor contributing to gout.

scientific article published in December 2011

Identification of a hypouricemia patient with SLC2A9 R380W, a pathogenic mutation for renal hypouricemia type 2

scientific article published on 01 January 2014

Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus.

scientific article

Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout risk

scientific article

Meta-analysis confirms an association between gout and a common variant of LRRC16A locus

scientific article published on 01 September 2016

Mutations in Glucose Transporter 9 Gene SLC2A9 Cause Renal Hypouricemia

scientific article

NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout

scientific article

Pathogenic GLUT9 mutations causing renal hypouricemia type 2 (RHUC2).

scientific article published in December 2011

Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients

scientific article published on 1 April 2020

The effects of URAT1/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression.

scientific article published on 29 January 2016

The relationships between titers of anti-Ro or anti-La as measured by ELISA and salivary production rate with age correction

scientific article published on 18 July 2008

Transient degradation of myelin basic protein in the rat hippocampus following acute carbon monoxide poisoning.

scientific article published on 13 July 2010

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