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List of works by Maria Spies

A Molecular Throttle

scientific article (publication date: September 2003)

A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA

scientific article published in Nature Communications

A time for promiscuity in a eukaryotic recombinase.

scientific article published on June 2017

DNA Repair: Trust but Verify

scientific article published on 01 February 2013

Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair

scientific article published on 28 August 2020

Dynamics and selective remodeling of the DNA-binding domains of RPA

scientific article published on 04 February 2019

Engineering of functional replication protein a homologs based on insights into the evolution of oligonucleotide/oligosaccharide-binding folds

scientific article

Ensemble and single-molecule fluorescence-based assays to monitor DNA binding, translocation, and unwinding by iron-sulfur cluster containing helicases.

scientific article published on 16 February 2010

Expression, Purification, and Biochemical Evaluation of Human RAD51 Protein.

scientific article published on 9 January 2018

FRET-Based Assays to Monitor DNA Binding and Annealing by Rad52 Recombination Mediator Protein ⬇️

scientific article published on January 1, 2011

Ferroplasma acidarmanus RPA2 facilitates efficient unwinding of forked DNA substrates by monomers of FacXPD helicase

scientific article

G-quadruplex recognition and remodeling by the FANCJ helicase

scientific article published on 24 June 2016

Helicase SPRNTing through the nanopore

scientific article

Inching over hurdles: how DNA helicases move on crowded lattices

scientific article published on 06 May 2010

Observation and Analysis of RAD51 Nucleation Dynamics at Single-Monomer Resolution

scientific article published in February 2018

PCNA tool belts and polymerase bridges form during translesion synthesis

scientific article published on 20 June 2016

Preface

Preface

scientific article published on 01 January 2018

Preface

Preface

Protein-nucleic acids interactions: new ways of connecting structure, dynamics and function

scientific article published on 4 August 2017

Quantifying the Assembly of Multicomponent Molecular Machines by Single-Molecule Total Internal Reflection Fluorescence Microscopy

scientific article published on 10 October 2016

RAD51 discrimination between single- and double-strand DNA: a matter of flexibility and enthalpy

scientific article published on 24 February 2020

Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation

scientific article published on 29 March 2019

RecBCD enzyme is a bipolar DNA helicase

scientific article

Regulation of translocation polarity by helicase domain 1 in SF2B helicases

scientific article published on 11 November 2011

Single-molecule analysis reveals differential effect of ssDNA-binding proteins on DNA translocation by XPD helicase

scientific article

Single-molecule sorting of DNA helicases

scientific article

Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells

scientific article published on 19 July 2016

Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function

scientific article

The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1

scientific article (publication date: 22 February 2016)

The RadA protein from a hyperthermophilic archaeon Pyrobaculum islandicum is a DNA-dependent ATPase that exhibits two disparate catalytic modes, with a transition temperature at 75 degrees C.

scientific article published in February 2000

The RecA binding locus of RecBCD is a general domain for recruitment of DNA strand exchange proteins

scientific article published in February 2006

The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain.

scientific article

The iron-containing domain is essential in Rad3 helicases for coupling of ATP hydrolysis to DNA translocation and for targeting the helicase to the single-stranded DNA-double-stranded DNA junction

scientific article published on 20 November 2007

There and back again: new single-molecule insights in the motion of DNA repair proteins ⬇️

scientific article published on December 21, 2012

Translocation by the RecB motor is an absolute requirement for {chi}-recognition and RecA protein loading by RecBCD enzyme

scientific article

Two steps forward, one step back: determining XPD helicase mechanism by single-molecule fluorescence and high-resolution optical tweezers.

scientific article published on 21 February 2014

Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.

scientific article

Tyrosine phosphorylation stimulates activity of human RAD51 recombinase through altered nucleoprotein filament dynamics

scientific article

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