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List of works by Paul J Hertzog

A cell type-specific transcriptomic approach to map B cell and monocyte type I interferon-linked pathogenic signatures in Multiple Sclerosis

scientific article published on 30 April 2019

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling.

scientific article published on 13 March 2017

A human CD2 minigene directs CRE-mediated recombination in T cells in vivo

article

A notch in the toll belt

scientific article published in November 2008

A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans

scientific article published on 8 January 2018

A structural "star" in interferon gamma signaling

scientific article published on 01 May 2019

Aberrant activation of JAK/STAT pathway components in response to G-CSF, interferon-alpha/beta and interferon-gamma in NFS-60 cells

scientific article

Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion

scientific article

Adamts-1 is essential for the development and function of the urogenital system

scientific journal article

Administration of imiquimod, an interferon inducer, in asymptomatic human immunodeficiency virus-infected persons to determine safety and biologic response modification

scientific article published in September 1998

Akt phosphorylation and NFκB activation are counterregulated under conditions of oxidative stress

scientific article published on 01 November 2004

An imbalance in antioxidant defense affects cellular function: the pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse

scientific article

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation.

scientific article

Animal models in the study of the biological function of genes on human chromosome 21 and their role in the pathophysiology of Down syndrome ⬇️

scientific article published on January 1, 1997

Antiproliferative potencies of interferons on melanoma cell lines and xenografts: higher efficacy of interferon beta

scientific article published on August 5, 1992

Antitumour actions of interferons: implications for cancer therapy

scientific article published on February 2016

Author Correction: Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

scientific article

Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells

article

Binding of interferon-alpha and -beta to a component of the human type I interferon receptor expressed in simian cells

scientific article published on 01 August 1996

Biological and chemical studies on 8,9-dihydroxy-8,9-dihydro-aflatoxin B1 and some of its esters ⬇️

scientific article published on January 1, 1980

Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responses

scientific article

Blocking Monoclonal Antibodies Specific for Mouse IFN-α/β Receptor Subunit 1 (IFNAR-1) from Mice Immunized by In Vivo Hydrodynamic Transfection

article

Brief Report: Identification of a Pathogenic Variant in TREX1 in Early-Onset Cerebral Systemic Lupus Erythematosus by Whole-Exome Sequencing

scientific article published on 01 December 2014

Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

article

Characterization and transcriptional analysis of the mouse Chromosome 16 cytokine receptor gene cluster

scientific article published on February 2003

Characterization of monoclonal antibodies specific to the transcription factor ETS-2 protein

scientific article published on 01 March 2003

Characterization of the type I interferon locus and identification of novel genes

scientific article

Chemokine receptor CCR5 is not required for development of experimental autoimmune gastritis.

scientific article

Choice of mouse strains for gene targeting.

scientific article

CiiiDER: A tool for predicting and analysing transcription factor binding sites

scientific article published on 04 September 2019

Cloning and Characterization of Soluble and Transmembrane Isoforms of a Novel Component of the Murine Type I Interferon Receptor, IFNAR 2 ⬇️

scientific article published on September 19, 1997

Comparative Metabolomics and Transcriptomics Reveal Multiple Pathways Associated with Polymyxin Killing in Pseudomonas aeruginosa

scientific article published on 08 January 2019

Comparison of mice born after intracytoplasmic sperm injection with in vitro fertilization and natural mating

scientific article published in April 2007

Comparison of the effects of Enovid and α-naphthylisothiocyanate on bromosulphophthalein excretion in Syrian golden hamsters

scientific article published on 01 March 1980

Concurrent Host-Pathogen Transcriptional Responses in a Clostridium perfringens Murine Myonecrosis Infection.

scientific article

Constitutive activation of gp130 leads to neuroendocrine differentiation in vitro and in vivo

scientific article published on February 2005

Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection

scientific article published in 2023

CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus

scientific article published on 14 May 2013

Cutting Edge: Pulmonary Legionella pneumophila Is Controlled by Plasmacytoid Dendritic Cells but Not Type I IFN

scientific article published on 16 April 2010

Defining the distinct, intrinsic properties of the novel type I interferon, epsilon.

scientific article

Dendritic cell precursor populations of mouse blood: identification of the murine homologues of human blood plasmacytoid pre-DC2 and CD11c+ DC1 precursors

scientific article published on 10 October 2002

Desrt, an AT-rich interaction domain family transcription factor gene, is an early marker for nephrogenic mesoderm and is expressed dynamically during mouse limb development

scientific article published on 01 June 2001

Detection of cells producing murine interferon-α using antipeptide antibodies

scientific article published on 01 June 1994

Different interactions of interferon-alpha subtypes at the surface of epithelial and lymphoid cells

scientific article published on August 1, 1992

Differential Effect of Several Inducers on Hepatic and Mammary Benzo (A) Pyrene Metabolism in Rat and Hamster

scientific article published on 01 January 1981

Differential expression and effects of gp130 cytokines and receptors in prostate cancer cells

scientific article published on November 2004

Differentiation-associated changes in mucin glycoprotein antigenicity in mucosa adjacent to rare gastrointestinal tract tumours of non-mucosal origin

scientific article published on 01 February 1993

Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death

scientific journal article

Down syndrome and mouse models

scientific article published in June 1998

Dynamic control of type I IFN signalling by an integrated network of negative regulators

scientific article published on 25 February 2015

Early T-BET Expression Ensures an Appropriate CD8+ Lineage-Specific Transcriptional Landscape after Influenza A Virus Infection

scientific article published on 21 June 2019

Endogenous interferon-alpha production by differentiating human monocytes regulates expression and function of the IL-2/IL-4 receptor gamma chain.

scientific article

Epstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5

scientific article

Ets-2 is induced by oxidative stress and sensitizes cells to H(2)O(2)-induced apoptosis: implications for Down's syndrome

scientific article

Ets1 as a marker of malignant potential in gastric carcinoma ⬇️

scientific article published on October 1, 2003

Ets2 is expressed during morphogenesis of the somite and limb in the mouse embryo

scientific article published on August 2002

Expression of a novel family of epitopes on small intestinal mucins in colorectal cancers, adjacent and remote mucosa

scientific article published on 01 January 1992

Expression of large intestinal mucin antigen (LIMA) epitopes in the normal and neoplastic gastrointestinal tract.

scientific article

Factors determining the spontaneous activation of splenic dendritic cells in culture

article

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

scientific journal article

Fine tuning type I interferon responses ⬇️

scientific article published on May 25, 2013

Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

scientific article

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

scientific article published on 30 April 2009

GM-CSF-induced autoimmune gastritis in interferon α receptor deficient mice

article

Generation and characterization of neuregulin-2-deficient mice.

scientific article published on September 2004

Generation and characterization of recombinant unmodified and phosphorylatable murine IFN-alpha1 in the methylotropic yeast Pichia pastoris.

scientific article published on July 2003

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

scientific article published on 29 February 2016

Glucocorticosteroids enhance replication of respiratory viruses: effect of adjuvant interferon

scientific article

Glutathione Peroxidase-1 Contributes to the Neuroprotection Seen in the Superoxide Dismutase-1 Transgenic Mouse in Response to Ischemia/Reperfusion Injury

article

HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production

scientific article

Helicobacter pylori VacA Suppresses Lactobacillus acidophilus-Induced Interferon Beta Signaling in Macrophages via Alterations in the Endocytic Pathway ⬇️

scientific article published on June 11, 2013

IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection

scientific article

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

scientific article

IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.

scientific article published on 10 December 2010

INTERFEROME: the database of interferon regulated genes

scientific article

Identification and expression analysis of alternative transcripts of the mouse GA-binding protein (Gabp) subunits alpha and beta1.

scientific article published on 23 November 2004

Immunolocalisation of interferon-alpha in hepatitis C patients and its correlation with response to interferon-alpha therapy

scientific article published on 01 November 1994

In vivo comparison of local versus systemic delivery of immunostimulating siRNA in HPV-driven tumours.

scientific article published on 12 November 2013

Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells

scientific article

Inflammasome-dependent IFN-γ drives pathogenesis in Streptococcus pneumoniae meningitis.

scientific article published on 15 October 2012

Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

scientific article published on 03 July 2019

Interferome v2.0: an updated database of annotated interferon-regulated genes

scientific article

Interferon epsilon promotes HIV restriction at multiple steps of viral replication

scientific article published on 3 January 2017

Interferon-γ: an overview of signals, mechanisms and functions ⬇️

scientific article (publication date: February 2004)

Interferon-ε protects the female reproductive tract from viral and bacterial infection

scientific journal article

Interferons as biomarkers and effectors: lessons learned from animal models.

scientific article published on April 2012

Intermittent interferonemia and interferon responses in multiple sclerosis ⬇️

scientific article published on January 1, 1991

Isolation of embryonic fibroblasts and their use in the in vitro characterization of gene function.

scientific article

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

scientific journal article

LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling.

scientific article

Lack of glutathione peroxidase-1 exacerbates Abeta-mediated neurotoxicity in cortical neurons

scientific article

Liver plasma membrane enzyme activities following glutaraldehyde fixation ⬇️

scientific article published on January 1, 1976

Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer

scientific article published on 21 July 2015

Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis

scientific article

Macrophage lineage phenotypes and osteoclastogenesis—Complexity in the control by GM-CSF and TGF-β

article

Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4.

scientific article published on 9 July 2004

Mechanism of Interferon Stimulated Gene Induction in HIV-1 Infected Macrophages

scientific article published on 2 August 2017

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

scientific article

MicroRNA as Type I Interferon-Regulated Transcripts and Modulators of the Innate Immune Response

scientific article

Mitochondrially localised MUL1 is a novel modulator of antiviral signaling

scientific article

Molecular detection of interferon-alpha expression in multiple sclerosis brain

scientific article

Monoclonal antibodies against subunits of yeast mitochondrial H+-ATPase ⬇️

scientific article published on June 26, 1984

Multiple regions within the promoter of the murine Ifnar-2 gene confer basal and inducible expression

scientific article published on July 2002

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

scientific article published on 10 July 2009

MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7.

scientific article published on 15 August 2012

Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.

scientific article

Neonatal calyceal dilation and renal fibrosis resulting from loss of Adamts-1 in mouse kidney is due to a developmental dysgenesis

scientific article published on 22 December 2004

Non-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in mice

scientific article

Oncofetal expression of the human intestinal mucin glycoprotein antigens in gastrointestinal epithelium defined by monoclonal antibodies ⬇️

scientific article published on May 30, 1991

Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis.

scientific article

Overview of cytokine and growth factor review focus on Australia ⬇️

scientific article published on May 18, 2013

Overview. Type I interferons as primers, activators and inhibitors of innate and adaptive immune responses ⬇️

scientific article published on May 1, 2012

Overview: Gene Knockouts

article

PROPERTIES AND FUNCTIONS OF THE NOVEL TYPE I INTERFERON EPSILON

scientific article published on 01 June 2019

Plasmacytoid dendritic cell heterogeneity is defined by CXCL10 expression following TLR7 stimulation

scientific article published on 25 June 2018

Post‐transcriptional regulation of interferon‐alpha 4 subtype production by lymphoblastoid cells ⬇️

scientific article published on 01 January 1993

Potential contribution of NF-kappaB in neuronal cell death in the glutathione peroxidase-1 knockout mouse in response to ischemia-reperfusion injury

scientific article

Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells

scientific article published on 6 November 2013

RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation

scientific article (publication date: 16 February 2017)

RNA-eXpress annotates novel transcript features in RNA-seq data.

scientific article

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

scientific article published on 10 June 2016

Recent advances in cytokines, cytokine receptors and signal transduction

scientific article published in June 1998

Regulation of H3K4me3 at Transcriptional Enhancers Characterizes Acquisition of Virus-Specific CD8+ T Cell-Lineage-Specific Function

scientific article published in December 2017

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation

scientific article

Role of interferons in the regulation of cell proliferation, differentiation, and development

scientific article published on October 1994

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine

scientific article published in September 1999

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

scientific article published on May 2008

Sculpting the immune response to infection ⬇️

scientific article published on June 20, 2011

Signaling Molecules Affecting Immune Response

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

scientific article published on 22 July 2012

Soluble IFN receptor potentiates in vivo type I IFN signaling and exacerbates TLR4-mediated septic shock

scientific article published on 2 April 2014

Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection

scientific article published on 13 November 2014

Structure-function studies based on in vitro expression

scientific article published on January 1995

Suppressor of Cytokine Signaling (SOCS) 1 Inhibits Type I Interferon (IFN) Signaling via the Interferon α Receptor (IFNAR1)-associated Tyrosine Kinase Tyk2 ⬇️

scientific article published on July 13, 2011

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

scientific article published on 15 January 2006

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

scientific article published on 27 November 2005

Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-Resistant Pseudomonas aeruginosa

scientific article published on 03 October 2019

Systems biology of interferon responses.

scientific article published on January 2011

TGF-betaRII rescues development of small intestinal epithelial cells in Elf3-deficient mice.

scientific article published on 25 February 2007

TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain

scientific article

Targeting of the ETS factor GABPalpha disrupts neuromuscular junction synaptic function.

scientific article published on 26 February 2007

The ETS transcription factor GABPalpha is essential for early embryogenesis

scientific article published on July 2004

The Ets transcription factor ELF5 functions as a tumor suppressor in the kidney.

scientific article

The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death

scientific article

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

scientific article published on 29 February 2016

The adenoma-carcinoma sequence in the colorectum--early appearance of a hierarchy of small intestinal mucin antigen (SIMA) epitopes and correlation with malignant potential.

scientific article

The apparent inhibition of urothelial DNA synthesis in neonatal rats by dietary saccharin

scientific article published on 01 August 1981

The binding of 7,12-dimethylbenz[a]anthracene to mammary gland macromolecules in the hamster:effects of Enovid feeding or transplacental exposure to diethylstilboestrol

scientific article published on October 1981

The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: implications for Down syndrome

scientific article published on July 2003

The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals

scientific article published on 16 December 2013

The effect of norethynodrel-mestranol pretreatment on hepatic metabolism of 7,12-dimethylbenz(a)anthracene in rats and hamsters

scientific article published on 01 June 1980

The failure of chronically administered saccharin to stimulate bladder epithelial DNA synthesis in F0 rats

scientific article published on 01 January 1981

The genomic profile of the cerebral cortex after closed head injury in mice: effects of minocycline

scientific article

The role of Ets2 transcription factor in the induction of microRNA-155 (miR-155) by lipopolysaccharide and its targeting by interleukin-10

scientific article published on 20 December 2013

The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone.

scientific article published on January 2013

The role of type I interferons in TLR responses.

scientific article published on 31 July 2007

Tissue-specific overexpression of the HSA21 gene GABPalpha: implications for DS.

scientific article

Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5.

scientific article

Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

scientific article published on 21 August 2017

Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity

scientific article

Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus.

scientific article published on 22 July 2009

Type I interferon receptors: biochemistry and biological functions.

scientific article

Type I interferons mediate the lipopolysaccharide induction of macrophage cyclin D2.

scientific article

Type I interferons suppress CD4⁺ T-cell-dependent parasite control during blood-stage Plasmodium infection

scientific article published on 8 August 2011

Type I-IFNs control GVHD and GVL responses after transplantation

article

Type-I interferon signalling through IFNAR1 plays a deleterious role in the outcome after stroke.

scientific article

Ultraviolet-induced apoptosis in embryonic stem cells in vitro

scientific article published on January 2006

Viruses 'chew the fat'!?

scientific article published on 14 January 2014

West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response

scientific article

α-Naphthyl-isothiocyanate-induced cholestasis in the rat: studies of liver plasma membrane enzymes ⬇️

scientific article published on January 1, 1975

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