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List of works by William O Hancock

"Artificial mitotic spindle" generated by dielectrophoresis and protein micropatterning supports bidirectional transport of kinesin-coated beads

scientific article

A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase Activity.

scientific article published in July 2017

A kinetic dissection of the fast and superprocessive kinesin-3 KIF1A reveals a predominate one-head-bound state during its chemomechanical cycle

scientific article published on 20 October 2020

A matrix computational approach to kinesin neck linker extension.

scientific article

Aging Gracefully: A New Model of Microtubule Growth and Catastrophe

scientific article published on December 2015

An EB1-kinesin complex is sufficient to steer microtubule growth in vitro

scientific article published on 23 January 2014

Anterograde microtubule transport drives microtubule bending in LLC-PK1 epithelial cells.

scientific article

Arabidopsis thaliana protein, ATK1, is a minus-end directed kinesin that exhibits non-processive movement.

scientific article published in July 2002

Bidirectional cargo transport: moving beyond tug of war.

scientific article published on 16 August 2014

Ca2+ and segment length dependence of isometric force kinetics in intact ferret cardiac muscle

scientific article published on 01 October 1993

Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin

scientific article

Cytoskeletal Organization: Whirling to the Beat ⬇️

scientific article published on June 19, 2012

Direct observation of individual tubulin dimers binding to growing microtubules

scientific article published on 25 February 2019

Directing transport of CoFe2O4-functionalized microtubules with magnetic fields

scientific article published on 01 January 2007

Dual inhibition of Kif15 by oxindole and quinazolinedione chemical probes

scientific article published on 04 December 2018

Eg5 Inhibitors Have Contrasting Effects on Microtubule Stability and Metaphase Spindle Integrity.

scientific article published on 6 February 2017

Engineered kinesin motor proteins amenable to small-molecule inhibition

scientific article

Engineering tubulin: microtubule functionalization approaches for nanoscale device applications

scientific article published on 16 February 2011

Enhancing the stability of kinesin motors for microscale transport applications

scientific article published on 6 December 2007

Estimating Velocity for Processive Motor Proteins with Random Detachment

scientific article published on June 2013

Examining kinesin processivity within a general gating framework.

scientific article published on 22 April 2015

High-Resolution Single-Molecule Kinesin Assays at kHz Frame Rates

scientific article published on 01 January 2018

Influence of Ca2+ on force redevelopment kinetics in skinned rat myocardium

scientific article

Insights into the Mechanical Properties of the Kinesin Neck Linker Domain from Sequence Analysis and Molecular Dynamics Simulations

scientific article

Interferometric Scattering Microscopy for the Study of Molecular Motors.

scientific article published on 10 October 2016

Intracellular transport: kinesins working together.

scientific article

Kinesin Processivity Is Determined by a Kinetic Race from a Vulnerable One-Head-Bound State

scientific article published in June 2017

Kinesin processivity is gated by phosphate release

scientific article

Kinesin's neck-linker determines its ability to navigate obstacles on the microtubule surface

scientific article

Kinesin's processivity results from mechanical and chemical coordination between the ATP hydrolysis cycles of the two motor domains.

scientific article

Kinesin's tail domain is an inhibitory regulator of the motor domain

scientific article published in September 1999

Kinesin-2 and Apc function at dendrite branch points to resolve microtubule collisions

scientific article

Kinesin-5 is a microtubule polymerase

scientific article

Kinesins with extended neck linkers: a chemomechanical model for variable-length stepping

scientific article published on 14 October 2011

Kinetics of nucleotide-dependent structural transitions in the kinesin-1 hydrolysis cycle

scientific article

Load-dependent detachment kinetics plays a key role in bidirectional cargo transport by kinesin and dynein

scientific article published on 01 April 2019

Magnet assisted fabrication of microtubule arrays.

scientific article published on 9 May 2006

Microscale transport and sorting by kinesin molecular motors

scientific article published in March 2004

Microtubule alignment and manipulation using AC electrokinetics

scientific article published in September 2008

Microtubule binding kinetics of membrane-bound kinesin-1 predicts high motor copy numbers on intracellular cargo

scientific article published on 10 December 2019

Microtubule transport, concentration and alignment in enclosed microfluidic channels

scientific article published in April 2007

Millimeter scale alignment of magnetic nanoparticle functionalized microtubules in magnetic fields

scientific article published on 01 November 2005

Mitotic kinesins in action: diffusive searching, directional switching, and ensemble coordination

scientific article published on 01 May 2018

Mitotic kinesins: a reason to delve into kinesin-12.

scientific article published in October 2014

Models of calcium activation account for differences between skeletal and cardiac force redevelopment kinetics

scientific article published on 01 December 1997

Molecular counting by photobleaching in protein complexes with many subunits: best practices and application to the cellulose synthesis complex

scientific article

Monte Carlo analysis of neck linker extension in kinesin molecular motors

scientific article

Motor Dynamics Underlying Cargo Transport by Pairs of Kinesin-1 and Kinesin-3 Motors

scientific article published on 05 February 2019

Motor Reattachment Kinetics Play a Dominant Role in Multimotor-Driven Cargo Transport

scientific article published in January 2018

Nanoscale patterning of kinesin motor proteins and its role in guiding microtubule motility

scientific article

Neck linker length determines the degree of processivity in kinesin-1 and kinesin-2 motors

scientific article published on 13 May 2010

Neutravidin micropatterning by deep UV irradiation

scientific article published on 13 August 2008

Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel

scientific article

Processivity of the kinesin-2 KIF3A results from rear head gating and not front head gating

scientific article

Processivity of the motor protein kinesin requires two heads

scientific article

Reconstitution and characterization of budding yeast gamma-tubulin complex

scientific article

Surface-bound casein modulates the adsorption and activity of kinesin on SiO2 surfaces.

scientific article published on April 2009

The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus

scientific article published on March 2016

The Kinesin-5 Chemomechanical Cycle Is Dominated by a Two-heads-bound State

scientific article published on 11 July 2016

The Orphan Kinesin PAKRP2 Achieves Processive Motility via a Noncanonical Stepping Mechanism

scientific article published on 28 February 2019

The S6 gate in regulatory Kv6 subunits restricts heteromeric K channel stoichiometry

article

The axonal transport motor kinesin-2 navigates microtubule obstacles via protofilament switching

scientific article

The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends

scientific article published in February 2003

The processivity of kinesin-2 motors suggests diminished front-head gating

scientific article published in March 2009

The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds.

scientific article

Transport and detection of unlabeled nucleotide targets by microtubules functionalized with molecular beacons.

scientific article published in March 2008

Transport by populations of fast and slow kinesins uncovers novel family-dependent motor characteristics important for in vivo function.

scientific article

Transport of semiconductor nanocrystals by kinesin molecular motors

scientific article published in May 2006

What is the correct stoichiometry of Kv2.1:Kv6.4 heteromers?

scientific article published on 20 October 2020

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