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List of works by Lee E. Eiden

A calcium-initiated signaling pathway propagated through calcineurin and cAMP response element-binding protein activates proenkephalin gene transcription after depolarization

scientific article

A distinct trans-Golgi network subcompartment for sorting of synaptic and granule proteins in neurons and neuroendocrine cells

scientific article

A new approach to investigating the relationship between productive infection and cytopathicity in vivo

scientific article published on 01 February 1997

A new site and mechanism of action for the widely used adenylate cyclase inhibitor SQ22,536

scientific article

A restrictive element 1 (RE-1) in the VIP gene modulates transcription in neuronal and non-neuronal cells in collaboration with an upstream tissue specifier element

scientific article published on March 2004

AIDS and the central nervous system. Examining pathobiology and testing therapeutic strategies in the SIV-infected rhesus monkey.

scientific article

Acute thyroid hormone increases noradrenergic responsiveness of rat atria in vitro

scientific article published on 01 August 1981

Analysis of the PC12 cell transcriptome after differentiation with pituitary adenylate cyclase-activating polypeptide (PACAP).

scientific article

Bovine chromogranin A sequence and distribution of its messenger RNA in endocrine tissues

scientific article

Brain virus burden and indoleamine-2,3-dioxygenase expression during lentiviral infection of rhesus monkey are concomitantly lowered by 6-chloro-2',3'-dideoxyguanosine

scientific article

COX1 and COX2 expression in non-neuronal cellular compartments of the rhesus macaque brain during lentiviral infection ⬇️

scientific article published on January 8, 2011

Calcium-dependent regulation of the enkephalin phenotype by neuronal activity during early ontogeny

scientific article published in January 1991

Cellular distribution of chromogranin A in excitatory, inhibitory, aminergic and peptidergic neurons of the rodent central nervous system.

scientific article

Chemical coding of the human gastrointestinal nervous system: cholinergic, VIPergic, and catecholaminergic phenotypes

scientific article published in April 2003

Cholecystokinin innervation of the ventral striatum: a morphological and radioimmunological study

scientific article published in February 1985

Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. I. Central nervous system

scientific article published in May 1998

Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. II. The peripheral nervous system

scientific article published on 01 May 1998

Chromogranin A, an "on/off" switch controlling dense-core secretory granule biogenesis

scientific article

Commentary on Chapters ‘Clinical and Developmental Aspects’ and ‘Stress Responses of the Adrenal Medulla’ ⬇️

scientific article published on November 19, 2010

Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity

scientific article

Cutaneous Merkel cells of the rat contain both dynorphin A and vesicular monoamine transporter type 1 (VMAT1) immunoreactivity

scientific article

Discovery of pituitary adenylate cyclase-activating polypeptide-regulated genes through microarray analyses in cell culture and in vivo.

scientific article

Discrete signal transduction pathway utilization by a neuropeptide (PACAP) and a cytokine (TNF-alpha) first messenger in chromaffin cells, inferred from coupled transcriptome-promoter analysis of regulated gene cohorts

scientific article published on 19 April 2013

Distribution of the vesicular acetylcholine transporter (VAChT) in the central and peripheral nervous systems of the rat

scientific article published on 01 January 1994

Dual presence of chromogranin A-like immunoreactivity in a population of endocrine-like cells and in nerve fibers in the human anal canal

scientific article

Endogenous PACAP acts as a stress response peptide to protect cerebellar neurons from ethanol or oxidative insult

scientific article

Enkephalins modulate the responsiveness of rat atria in vitro to norepinephrine

scientific article published on 01 May 1982

Expression cloning of a reserpine-sensitive vesicular monoamine transporter ⬇️

scientific article published on November 15, 1992

Expression of vesicular monoamine transporters in endocrine hyperplasia and endocrine tumors of the oxyntic stomach

scientific article published on 01 September 1999

Five discrete cis-active domains direct cell type-specific transcription of the vasoactive intestinal peptide (VIP) gene

scientific article published in July 1998

Foreword to special issue: molecular and cellular mechanisms of VIP, PACAP and secretin signaling applied to systems biology.

scientific article

Fractalkine expression in the rhesus monkey brain during lentivirus infection and its control by 6-chloro-2',3'-dideoxyguanosine

scientific article published in December 2006

From the cholinergic gene locus to the cholinergic neuron

scientific article published in October 1998

Functional expression of dihydropyridine-insensitive calcium channels during PC12 cell differentiation by nerve growth factor (NGF), oncogenic ras, or src tyrosine kinase

scientific article published on June 1990

Fusion polypeptides that inhibit exocytosis: fusing aptamer and cell-penetrating peptide technologies and pharmacologies

scientific article published on 26 January 2005

Human and monkey cholinergic neurons visualized in paraffin-embedded tissues by immunoreactivity for VAChT, the vesicular acetylcholine transporter

scientific article published in January 1995

Human sorbin is generated via splicing of an alternative transcript from the ArgBP2 gene locus

scientific article published in July 2005

Identification of a region from the human cholinergic gene locus that targets expression of the vesicular acetylcholine transporter to a subset of neurons in the medial habenular nucleus in transgenic mice

scientific article published in December 2003

Immune-Neuroendocrine Integration at the Adrenal Gland: Cytokine Control of the Adrenomedullary Transcriptome ⬇️

scientific article published on March 16, 2012

Increase of C1q biosynthesis in brain microglia and macrophages during lentivirus infection in the rhesus macaque is sensitive to antiretroviral treatment with 6-chloro-2',3'-dideoxyguanosine

scientific article

Increased APOBEC3G expression is associated with extensive G-to-A hypermutation in viral DNA in rhesus macaque brain during lentiviral infection

scientific article published in October 2007

Independent patterns of transcription for the products of the rat cholinergic gene locus

scientific article published in January 2001

Induction of serpinb1a by PACAP or NGF is required for PC12 cells survival after serum withdrawal

scientific article

Interleukin-1 alpha and tumor necrosis factor-alpha differentially regulate enkephalin, vasoactive intestinal polypeptide, neurotensin, and substance P biosynthesis in chromaffin cells

scientific article published on 01 April 1992

Is PACAP the Major Neurotransmitter for Stress Transduction at the Adrenomedullary Synapse? ⬇️

scientific article published on May 18, 2012

Lentiviral Infection of Rhesus Macaques Causes Long-Term Injury to Cortical and Hippocampal Projections of Prostaglandin-Expressing Cholinergic Basal Forebrain Neurons ⬇️

scientific article published on January 1, 2012

Lipocalin 2: novel component of proinflammatory signaling in Alzheimer's disease

scientific article

Localization and expression of VMAT2 aross mammalian species: a translational guide for its visualization and targeting in health and disease.

scientific article published on January 2013

Localization of vesicular monoamine transporter isoforms (VMAT1 and VMAT2) to endocrine cells and neurons in rat

scientific article published on 01 January 1994

Meta-analysis of microarray-derived data from PACAP-deficient adrenal gland in vivo and PACAP-treated chromaffin cells identifies distinct classes of PACAP-regulated genes.

scientific article

Methionine and leucine enkephalin in rat neurohypophysis: different responses to osmotic stimuli and T2 toxin

scientific article published on May 1985

Microarray and suppression subtractive hybridization analyses of gene expression in pheochromocytoma cells reveal pleiotropic effects of pituitary adenylate cyclase-activating polypeptide on cell proliferation, survival, and adhesion.

scientific article published in June 2003

Molecular biology of the vesicular ACh transporter

scientific article

Neuropeptide genes: targets of activity-dependent signal transduction

scientific article published on January 1996

Neuropeptide-catecholamine interactions in stress

scientific article published on January 2013

Neuropeptides, growth factors, and cytokines: a cohort of informational molecules whose expression is up-regulated by the stress-associated slow transmitter PACAP in chromaffin cells

scientific article

Neuroprotection by endogenous and exogenous PACAP following stroke.

scientific article

Nicotinic receptor stimulation activates enkephalin release and biosynthesis in adrenal chromaffin cells

scientific article published on 01 December 1984

Ontogeny of Vesicular Amine Transporter Expression in the Rat: New Perspectives on Aminergic Neuronal and Neuroendocrine Differentiation

scientific article published on January 1, 1998

PAC1hop receptor activation facilitates catecholamine secretion selectively through 2-APB-sensitive Ca(2+) channels in PC12 cells

scientific article

PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cells ⬇️

scientific article published on June 12, 2011

PACAP controls adrenomedullary catecholamine secretion and expression of catecholamine biosynthetic enzymes at high splanchnic nerve firing rates characteristic of stress transduction in male mice

scientific article

PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis

scientific article published on 04 March 2013

PACAP-cytokine interactions govern adrenal neuropeptide biosynthesis after systemic administration of LPS.

scientific article published on 31 July 2009

PACAP-deficient mice show attenuated corticosterone secretion and fail to develop depressive behavior during chronic social defeat stress

scientific article published on 11 October 2012

PACAP: a master regulator of neuroendocrine stress circuits and the cellular stress response

scientific article published on March 2011

Phox2 and dHAND transcription factors select shared and unique target genes in the noradrenergic cell type

scientific article

Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis

scientific article

Pituitary adenylate cyclase-activating polypeptide regulation of vasoactive intestinal polypeptide transcription requires Ca2+ influx and activation of the serine/threonine phosphatase calcineurin

scientific article published in October 1999

Preface. The Tenth International Catecholamine Symposium (XICS).

scientific article published on January 2013

Primary structure of rat chromogranin A and distribution of its mRNA.

scientific article published in January 1988

Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA

scientific article

Proceedings of the 15th International Symposium on Chromaffin Cell Biology: the chromaffin cell as a stress transducer. Nov 12-16th, 2009, Yucatan, Mexico

scientific article

Recombinant DNA methods in neuroendocrinology: new answers to old questions

scientific article published on 01 May 1982

Reduced GABAergic inhibition in the basolateral amygdala and the development of anxiety-like behaviors after mild traumatic brain injury.

scientific article

Regional distribution and partial molecular characterization of CD4-related mRNA in human brain and peripheral tissues ⬇️

scientific article (publication date: April 1991)

Regulatory peptides and systems biology: A new era of translational and reverse-translational neuroendocrinology

scientific article published on 14 March 2020

Reserpine- and tetrabenazine-sensitive transport of (3)H-histamine by the neuronal isoform of the vesicular monoamine transporter

scientific article

STC1 induction by PACAP is mediated through cAMP and ERK1/2 but not PKA in cultured cortical neurons

scientific article published on January 2012

Satb2-independent acquisition of the cholinergic sudomotor phenotype in rodents

scientific article

Signaling through the neuropeptide GPCR PAC1induces neuritogenesisviaa single linear cAMP‐ and ERK‐dependent pathway using a novel cAMP sensor ⬇️

scientific article published on April 24, 2012

Somatomotor neuron-specific expression of the human cholinergic gene locus in transgenic mice

scientific article (publication date: 2000)

Species-specific vesicular monoamine transporter 2 (VMAT2) expression in mammalian pancreatic beta cells: implications for optimising radioligand-based human beta cell mass (BCM) imaging in animal models.

scientific article published on 13 February 2013

Spontaneous electrical activity regulates vasoactive intestinal peptide expression in dissociated spinal cord cell cultures

scientific article published in June 1991

Subcellular localization of chromogranins, calcium channels, amine carriers, and proteins of the exocytotic machinery in bovine splenic nerve

scientific article published on 01 March 1999

Synergistic action of upstream elements and a promoter-proximal CRE is required for neuroendocrine cell-specific expression and second-messenger regulation of the gene encoding the human secretory protein secretogranin II.

scientific article

Target-independent cholinergic differentiation in the rat sympathetic nervous system

scientific article

Temporal course of changes in gene expression suggests a cytokine-related mechanism for long-term hippocampal alteration after controlled cortical impact.

scientific article published on 03 March 2014

Temporally restricted role of retinal PACAP: integration of the phase-advancing light signal to the SCN.

scientific article

The Chromogranins: Their Roles in Secretion from Neuroendocrine Cells and as Markers for Neuroendocrine Neoplasia ⬇️

scientific article published on January 1, 2003

The class II MHC and HIV-1 binding surfaces of CD4.

scientific article

The hop cassette of the PAC1 receptor confers coupling to Ca2+ elevation required for pituitary adenylate cyclase-activating polypeptide-evoked neurosecretion

scientific article

The neurotrophic effects of PACAP in PC12 cells: control by multiple transduction pathways.

scientific article published on July 2006

The proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1 stimulate neuropeptide gene transcription and secretion in adrenochromaffin cells via activation of extracellularly regulated kinase 1/2 and p38 protein kinases, and activat

scientific article published on 15 April 2004

The role of chromogranin A and the control of secretory granule genesis and maturation

scientific article published in March 2003

The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine

scientific article

The vesicular monoamine transporter 2 (VMAT2) is expressed by normal and tumor cutaneous mast cells and Langerhans cells of the skin but is absent from Langerhans cell histiocytosis

scientific article published in June 2004

Three types of tyrosine hydroxylase-positive CNS neurons distinguished by dopa decarboxylase and VMAT2 co-expression.

scientific article published on 31 May 2006

Timing the Phox-trot: duration of Phox2a-dependent transcription is controlled by an intramolecular dephosphorylation/phosphorylation clock

scientific article published on 27 July 2009

Transcription Regulation Coupled to Calcium and Protein Kinase Signaling Systems through TRE-and CRE-Like Sequences in Neuropeptide Genes

scientific article published on 01 January 1998

Tumor necrosis factor (TNF)-alpha persistently activates nuclear factor-kappaB signaling through the type 2 TNF receptor in chromaffin cells: implications for long-term regulation of neuropeptide gene expression in inflammation

scientific article published on 21 February 2008

Two chemically and immunologically distinct forms of luteinizing hormone-releasing hormone are differentially expressed in frog neural tissues

scientific article published in May 1982

Two peptidases that convert 125I-Lys-Arg-(Met)enkephalin and 125I-(Met)enkephalin-Arg6, respectively, to 125I-(Met)enkephalin in bovine adrenal medullary chromaffin granules

scientific article published on 01 July 1984

Two separate cis-active elements of the vasoactive intestinal peptide gene mediate constitutive and inducible transcription by binding different sets of AP-1 proteins

scientific article published on September 1999

Upregulation of COX-2 and CGRP expression in resident cells of the Borna disease virus-infected brain is dependent upon inflammation

scientific article published in February 1999

VIP and NPY expression during differentiation of cholinergic and noradrenergic sympathetic neurons

scientific article published in December 1998

VMAT2: a dynamic regulator of brain monoaminergic neuronal function interacting with drugs of abuse

scientific article

Vasoactive intestinal polypeptide afferents to the bed nucleus of the stria terminalis in the rat: an immunohistochemical and biochemical study

scientific article published in August 1985

Vesicular amine transporter expression and isoform selection in developing brain, peripheral nervous system and gut.

scientific article published in March 1998

Vesicular monoamine transporter 2 (VMAT2) expression in hematopoietic cells and in patients with systemic mastocytosis.

scientific article

pathFinder: a static network analysis tool for pharmacological analysis of signal transduction pathways.

scientific article published on 05 August 2008

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