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List of works by John H. Dawson

A heme-based redox sensor in the methanogenic archaeon Methanosarcina acetivorans

scientific article published on 09 May 2013

A novel intermediate in the reaction of seleno CYP119 with m-chloroperbenzoic acid

scientific article

A study of the K(+)-site mutant of ascorbate peroxidase: mutations of protein residues on the proximal side of the heme cause changes in iron ligation on the distal side

scientific article published on 01 February 1999

Alkylamine-ligated H93G myoglobin cavity mutant: a model system for endogenous lysine and terminal amine ligation in heme proteins such as nitrite reductase and cytochrome f.

scientific article

Amphitrite ornata Dehaloperoxidase (DHP): Investigations of Structural Factors That Influence the Mechanism of Halophenol Dehalogenation Using “Peroxidase-like” Myoglobin Mutants and “Myoglobin-like” DHP Mutants ⬇️

scientific article published on August 30, 2011

Amphitrite ornata dehaloperoxidase: enhanced activity for the catalytically active globin using MCPBA.

scientific article published in November 2004

Assignment of the heme axial ligand(s) for the ferric myoglobin (H93G) and heme oxygenase (H25A) cavity mutants as oxygen donors using magnetic circular dichroism

scientific article

C. fumago chloroperoxidase is also a dehaloperoxidase: oxidative dehalogenation of halophenols

scientific article published in February 2006

Caldariomyces fumago chloroperoxidase catalyzes the oxidative dehalogenation of chlorophenols by a mechanism involving two one-electron steps

scientific article published on 9 November 2007

Characterization of Heme Ligation Properties of Rv0203, a Secreted Heme Binding Protein Involved in Mycobacterium tuberculosis Heme Uptake ⬇️

scientific article published on February 8, 2012

Characterization of SiaA, a streptococcal heme-binding protein associated with a heme ABC transport system

scientific article published on 02 February 2008

Characterization of the coral allene oxide synthase active site with UV-visible absorption, magnetic circular dichroism, and electron paramagnetic resonance spectroscopy: evidence for tyrosinate ligation to the ferric enzyme heme iron

scientific article published in 2001

Characterization of the periplasmic heme-binding protein shut from the heme uptake system of Shigella dysenteriae

scientific article published on 01 October 2005

Characterization of the spleen green hemeprotein with magnetic and natural circular dichroism spectroscopy: positive evidence for a myeloperoxidase-type active site

scientific article published on 01 September 1986

Complex of myoglobin with phenol bound in a proximal cavity ⬇️

scientific article published on November 19, 2012

Complexes of Dual-Function Hemoglobin/Dehaloperoxidase with Substrate 2,4,6-Trichlorophenol Are Inhibitory and Indicate Binding of Halophenol to Compound I ⬇️

scientific article published on August 29, 2013

Contributions from the 13th International Conference on Bioinorganic Chemistry. Preface

scientific article published on 01 May 2008

Coordination modes of tyrosinate-ligated catalase-type heme enzymes: magnetic circular dichroism studies of Plexaura homomalla allene oxide synthase, Mycobacterium avium ssp. paratuberculosis protein-2744c, and bovine liver catalase in their ferric

scientific article published in 2011

Cryoreduction EPR and 13C, 19F ENDOR study of substrate-bound substates and solvent kinetic isotope effects in the catalytic cycle of cytochrome P450cam and its T252A mutant

scientific article published on 23 September 2005

Design of a five-coordinate heme protein maquette: a spectroscopic model of deoxymyoglobin

scientific article published in December 2004

Direct observation of a novel perturbed oxyferrous catalytic intermediate during reduced putidaredoxin-initiated turnover of cytochrome P-450-CAM: probing the effector role of putidaredoxin in catalysis

scientific article published on 22 August 2005

EPR and ENDOR characterization of intermediates in the cryoreduced oxy-nitric oxide synthase heme domain with bound L-arginine or N(G)-hydroxyarginine

scientific article published in August 2002

EPR and ENDOR studies of cryoreduced compounds II of peroxidases and myoglobin. Proton-coupled electron transfer and protonation status of ferryl hemes

scientific article published on 12 April 2008

Effects of cyanogen bromide modification of the distal histidine on the spectroscopic and ligand binding properties of myoglobin: magnetic circular dichroism spectroscopy as a probe of distal water ligation in ferric high-spin histidine-bound heme p

scientific article published on 01 November 1991

Effects of urea and acetic acid on the heme axial ligation structure of ferric myoglobin at very acidic pH.

scientific article published on 19 July 2009

Electrochemistry of unfolded cytochrome c in neutral and acidic urea solutions

scientific article published in May 2005

Electron paramagnetic resonance and electron-nuclear double resonance studies of the reactions of cryogenerated hydroperoxoferric-hemoprotein intermediates

scientific article

Electron paramagnetic resonance investigations of exogenous ligand complexes of low-spin ferric chloroperoxidase: further support for endogenous thiolate ligation to the heme iron

scientific article published on 01 July 1991

Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation

scientific article published on 01 August 1999

EpoK, a cytochrome P450 involved in biosynthesis of the anticancer agents epothilones A and B. Substrate-mediated rescue of a P450 enzyme

scientific article published in November 2004

Epoxidation of olefins by hydroperoxo-ferric cytochrome P450.

scientific article published in March 2003

Essential thiol requirement to restore pterin- or substrate-binding capability and to regenerate native enzyme-type high-spin heme spectra in the Escherichia coli-expressed tetrahydrobiopterin-free oxygenase domain of neuronal nitric oxide synthase

article

Evaluation of electron-withdrawing group effects on heme binding in designed proteins: implications for heme a in cytochrome c oxidase

scientific article published on 01 June 2006

Evidence of the direct involvement of the substrate TCP radical in functional switching from oxyferrous O2 carrier to ferric peroxidase in the dual-function hemoglobin/dehaloperoxidase from Amphitrite ornata

scientific article published on 28 July 2014

Extensive studies of the heme coordination structure of indoleamine 2,3-dioxygenase and of tryptophan binding with magnetic and natural circular dichroism and electron paramagnetic resonance spectroscopy

scientific article published on 01 September 1984

Functional switching of Amphitrite ornata dehaloperoxidase from O2-binding globin to peroxidase enzyme facilitated by halophenol substrate and H2O2.

scientific article published in July 2010

Heme Binding Properties of Glyceraldehyde-3-phosphate Dehydrogenase ⬇️

scientific article published on October 15, 2012

Heme binding to the Mammalian circadian clock protein period 2 is nonspecific

scientific article published on May 2010

Histidine-tailed microperoxidase-10: a pH-dependent ligand switch

scientific article published on 01 December 1998

Horse heart myoglobin catalyzes the H2O2-dependent oxidative dehalogenation of chlorophenols to DNA-binding radicals and quinones

scientific article published on 04 August 2007

Hydroperoxoferric heme intermediate as a second electrophilic oxidant in cytochrome P450-catalyzed reactions.

scientific article published on 29 July 2004

Investigations of heme ligation and ligand switching in cytochromes p450 and p420.

scientific article published on 14 August 2013

Ligation of the iron in the heme-heme oxygenase complex: X-ray absorption, electronic absorption and magnetic circular dichroism studies

scientific article published on 01 July 1996

Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy

scientific article

Low-temperature stabilization and spectroscopic characterization of the dioxygen complex of the ferrous neuronal nitric oxide synthase oxygenase domain

scientific article published in June 1999

Magnetic circular dichroism of ferrous carbonyl adducts of cytochromes P-450 and P-420 and their synthetic models: further evidence for mercaptide as the fifth ligand to iron ⬇️

scientific article published on January 1, 1976

Magnetic circular dichroism spectroscopic characterization of the NOS-like protein from Geobacillus stearothermophilus (gsNOS).

scientific article published on 4 January 2010

Magnetic circular dichroism spectroscopy as a probe of axial heme ligand replacement in semisynthetic mutants of cytochrome c.

scientific article

Magnetic circular dichroism studies XXXIV. Improved instrumentation for MCD measurements

scientific article published on 01 May 1975

Magnetic circular dichroism studies XXXV. A comparison of cytochromes P-450 and P-448.

scientific article

Magnetic circular dichroism studies of the active site structure of hemoprotein H-450: comparison to cytochrome P-450 and sensitivity to pH effects

scientific article published on 01 December 1989

Molecular basis for the inability of an oxygen atom donor ligand to replace the natural sulfur donor heme axial ligand in cytochrome P450 catalysis. Spectroscopic characterization of the Cys436Ser CYP2B4 mutant

scientific article published on 11 December 2010

Mono- and bis-phosphine-ligated H93G myoglobin: spectral models for ferrous-phosphine and ferrous-CO cytochrome P450.

scientific article published on 21 March 2013

Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction

scholarly article

Notomastus lobatus chloroperoxidase and Amphitrite ornata dehaloperoxidase both contain histidine as their proximal heme iron ligand

scientific article published on 01 February 1997

On the use of iron octa-alkylporphyrins as models for protoporphyrin IX-containing heme systems in studies employing magnetic circular dichroism spectroscopy

scientific article published in February 1992

Oxoiron(IV) in chloroperoxidase compound II is basic: implications for P450 chemistry

scientific article published in June 2004

Oxygenated cytochrome P-450cam: evidence against axial histidine ligation of iron

scientific article published on 01 April 1978

Preparation and initial characterization of the compound I, II, and III states of iron methylchlorin-reconstituted horseradish peroxidase and myoglobin: models for key intermediates in iron chlorin enzymes

scientific article published on 01 December 2000

Probing the heme iron coordination structure of alkaline chloroperoxidase

scientific article published on 01 November 1996

Probing the oxyferrous and catalytically active ferryl states of Amphitrite ornata dehaloperoxidase by cryoreduction and EPR/ENDOR spectroscopy. Detection of compound I.

scientific article published on October 2010

Rapid freeze-quench ENDOR study of chloroperoxidase compound I: the site of the radical

scientific article published on 01 May 2006

Rapid kinetics investigations of peracid oxidation of ferric cytochrome P450cam: nature and possible function of compound ES.

scientific article published on 07 October 2006

Reaction of ferric cytochrome P450cam with peracids: kinetic characterization of intermediates on the reaction pathway

scientific article published on 21 March 2005

Redox-dependent stability, protonation, and reactivity of cysteine-bound heme proteins.

scientific article published on 07 January 2014

Replacement of the axial histidine heme ligand with cysteine in nitrophorin 1: spectroscopic and crystallographic characterization.

scientific article published on 16 October 2008

Replacement of tyrosine residues by phenylalanine in cytochrome P450cam alters the formation of Cpd II-like species in reactions with artificial oxidants

scientific article

Sensitizer-linked substrates and ligands: ruthenium probes of cytochrome P450 structure and mechanism

scientific article published in January 2002

Single turnover studies of oxidative halophenol dehalogenation by horseradish peroxidase reveal a mechanism involving two consecutive one electron steps: toward a functional halophenol bioremediation catalyst

scientific article published on 25 September 2012

Spectroscopic characterization of five- and six-coordinate ferrous-NO heme complexes. Evidence for heme Fe-proximal cysteinate bond cleavage in the ferrous-NO adducts of the Trp-409Tyr/Phe proximal environment mutants of neuronal nitric oxide syntha

scientific article published in March 2003

Spectroscopic characterization of the ferric states of Amphitrite ornata dehaloperoxidase and Notomastus lobatus chloroperoxidase: His-ligated peroxidases with globin-like proximal and distal properties

scientific article published on 06 March 2006

Spectroscopic investigations of intermediates in the reaction of cytochrome P450(BM3)-F87G with surrogate oxygen atom donors

scientific article published on 07 October 2006

Stabilization and spectroscopic characterization of the dioxygen complex of wild-type cytochrome P4502B4 (CYP2B4) and its distal side E301Q, T302A and proximal side F429H mutants at subzero temperatures

scientific article published on 13 July 2010

Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy

scientific article

Subzero-temperature stabilization and spectroscopic characterization of homogeneous oxyferrous complexes of the cytochrome P450 BM3 (CYP102) oxygenase domain and holoenzyme

scientific article

The H93G Myoglobin Cavity Mutant as a Versatile Scaffold for Modeling Heme Iron Coordination Structures in Protein Active Sites and Their Characterization with Magnetic Circular Dichroism Spectroscopy

scientific article published on April 2011

The H93G myoglobin cavity mutant as a versatile template for modeling heme proteins: ferrous, ferric, and ferryl mixed-ligand complexes with imidazole in the cavity

scientific article published on 01 December 2000

The Use of Deuterated Camphor as a Substrate in 1H ENDOR Studies of Hydroxylation by Cryoreduced Oxy P450cam Provides New Evidence of the Involvement of Compound I ⬇️

scientific article published on January 14, 2013

The active site structure of E. coli HPII catalase. Evidence favoring coordination of a tyrosinate proximal ligand to the chlorin iron.

scientific article published in December 1991

The ferric-hydroperoxo complex of chloroperoxidase

scientific article

The influence of oxygen donor ligation on the spectroscopic properties of ferric cytochrome P-450: ester, ether and ketone co-ordination to the haem iron

scientific article published on 01 January 1984

The influence of substrate on the spectral properties of oxyferrous wild-type and T252A cytochrome P450-CAM.

scientific article

The mechanism of oxidative halophenol dehalogenation by Amphitrite ornata dehaloperoxidase is initiated by H2O2 binding and involves two consecutive one-electron steps: role of ferryl intermediates

scientific article

Uncoupling oxygen transfer and electron transfer in the oxygenation of camphor analogues by cytochrome P450-CAM. Direct observation of an intermolecular isotope effect for substrate C-H activation

scientific article published on 01 November 1995

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