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List of works by Gilles J. Guillemin

3Rs-based optimization of mice behavioral testing: The habituation/dishabituation olfactory test

scientific article published on 12 December 2019

A beta 1-42 induces production of quinolinic acid by human macrophages and microglia

scientific article

A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality

scientific article published on 12 August 2014

Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers

scientific article published on 16 April 2015

Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations.

scientific article

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

scientific article published on 30 May 2015

Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats

scientific article

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

scientific article

Alpha-synuclein transmission and mitochondrial toxicity in primary human foetal enteric neurons in vitro

scientific article published on 12 September 2013

Alteration in Gene Pair Correlations in Tryptophan Metabolism as a Hallmark in Cancer Diagnosis

scientific article published on 10 December 2020

Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study.

scientific article published on 22 May 2018

Altered kynurenine pathway metabolism in autism: Implication for immune-induced glutamatergic activity.

scientific article published on 24 October 2015

Amelioration of Aluminum Maltolate-Induced Inflammation and Endoplasmic Reticulum Stress-Mediated Apoptosis by Tannoid Principles of Emblica officinalis in Neuronal Cellular Model

scientific article published on 21 September 2018

Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress

scientific article published on 04 December 2019

An effective, low-cost method for achieving and maintaining hypoxia during cell culture studies

scientific article published in October 2015

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

scientific article

Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton.

scientific article

Antioxidant therapies in attention deficit hyperactivity disorder

scientific article published on 01 January 2019

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

scientific article

Asiatic Acid Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress and Apoptosis Via AKT/GSK-3β Signaling Pathway in Wistar Rats

scientific article published on 22 January 2019

Autism and Gut-Brain Axis: Role of Probiotics

scientific article published on 01 January 2020

BMAA and Neurodegenerative Illness.

scientific article published on 24 May 2017

Bcl11b-A Critical Neurodevelopmental Transcription Factor-Roles in Health and Disease.

scientific article

Bcl11b: A New Piece to the Complex Puzzle of Amyotrophic Lateral Sclerosis Neuropathogenesis?

scientific article

Beneficial effects of coating alginate microcapsules with macromolecular heparin conjugates-in vitro and in vivo study

scientific article published on 2 October 2013

Beneficial effects of desferrioxamine on encapsulated human islets--in vitro and in vivo study

scientific article published on September 2010

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

scientific article published on 15 April 2016

Central kynurenine pathway shift with age in women

scientific article published on 16 December 2015

Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons

scientific article published on 16 May 2014

Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats.

scientific article published in November 2011

Characterisation of kynurenine pathway metabolism in human astrocytes and implications in neuropathogenesis

scientific article

Characterisation of the expression of NMDA receptors in human astrocytes

scientific article (publication date: 2010)

Characterisation of the kynurenine pathway in skin-derived fibroblasts and keratinocytes.

scientific article published on June 2015

Characterization of functional polymorphisms and glucocorticoid-responsive elements in the promoter of TDO2, a candidate gene for ethanol-induced behavioural disorders

scientific article published on 4 April 2013

Characterization of the Kynurenine Pathway in CD8+ Human Primary Monocyte-Derived Dendritic Cells.

scientific article

Characterization of the kynurenine pathway and quinolinic Acid production in macaque macrophages.

scientific article published on 15 May 2013

Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis

scientific article published on 28 January 2011

Characterization of the kynurenine pathway in human neurons

scientific article published on November 2007

Characterization of the phenotypic and lymphokine profile associated with strong CD8+ anti-HIV-1 suppressor activity (CASA).

scientific article published on January 2002

Chemical reprogramming enhances homology-directed genome editing in zebrafish embryos

scientific article published on 23 May 2019

Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine

scientific article

Chronic exposure of human neurons to quinolinic acid results in neuronal changes consistent with AIDS dementia complex ⬇️

scientific article published on March 5, 1998

Chronic mild stress augments MPTP induced neurotoxicity in a murine model of Parkinson's disease.

scientific article published on 6 February 2017

Cocoa beans improve mitochondrial biogenesis via PPARγ/PGC1α dependent signalling pathway in MPP+ intoxicated human neuroblastoma cells (SH-SY5Y)

scientific article published on 12 September 2018

Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry

scientific article published in February 2002

Connecting inflammation with glutamate agonism in suicidality.

scientific article published on 3 December 2012

Consumption of fig fruits grown in Oman can improve memory, anxiety, and learning skills in a transgenic mice model of Alzheimer's disease.

scientific article published on 18 June 2014

Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease

scientific article published on 28 July 2016

Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau

scientific article published on 01 April 2019

Cross-Linking Cellular Prion Protein Induces Neuronal Type 2-Like Hypersensitivity

scientific article published on 30 July 2021

Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis

scientific article

Cytotoxic Effects of Environmental Toxins on Human Glial Cells.

scientific article published on 29 October 2016

Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2.

scientific article published on 07 September 2015

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis

scientific article published in September 2017

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.

scientific article published on 9 April 2015

Demethoxycurcumin, a Natural Derivative of Curcumin Abrogates Rotenone-induced Dopamine Depletion and Motor Deficits by Its Antioxidative and Anti-inflammatory Properties in Parkinsonian Rats.

scientific article published in January 2018

Dendritic spines: Revisiting the physiological role

scientific article published on 15 January 2019

Design and screening of a glial cell-specific, cell penetrating peptide for therapeutic applications in multiple sclerosis.

scientific article

Detection of the suspected neurotoxin β-methylamino- l -alanine (BMAA) in cyanobacterial blooms from multiple water bodies in Eastern Australia

article

Development of a Rapid Fluorescence-Based High-Throughput Screening Assay to Identify Novel Kynurenine 3-Monooxygenase Inhibitor Scaffolds

scientific article published on 8 February 2018

Diet rich in date palm fruits improves memory, learning and reduces beta amyloid in transgenic mouse model of Alzheimer's disease

scientific article published on April 2015

Dietary Supplementation of Walnut Partially Reverses 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Neurodegeneration in a Mouse Model of Parkinson’s Disease

scientific article published on 06 May 2015

Dietary Supplements/Antioxidants: Impact on Redox Status in Brain Diseases

scientific article published on 26 April 2017

Differential expression of sirtuins in the aging rat brain

scientific article published on 8 May 2015

Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression

scientific article published on 27 October 2020

Does escitalopram reduce neurotoxicity in major depression?

scientific article published on 12 May 2015

Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia

scientific article published on 03 April 2019

Editorial ISTRY Special Issue

scientific article published on 10 June 2010

Editorial: Glial Cells: Managers of Neuro-Immunity

scientific article

Effect of alginate encapsulation on the cellular transcriptome of human islets

scientific article

Effect of dietary supplementation of dates in Alzheimer's disease APPsw/2576 transgenic mice on oxidative stress and antioxidant status

scientific article published on 21 June 2014

Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: amelioration by COX-2 inhibition

scientific article published on 27 May 2014

Effect of prolonged gelling time on the intrinsic properties of barium alginate microcapsules and its biocompatibility

scientific article published on 10 August 2011

Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease.

scientific article published on 10 December 2009

Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons.

scientific article published on 08 May 2011

Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons.

scientific article published on 03 April 2009

Effects of Sleep Deprivation on the Tryptophan Metabolism

scientific article published on 23 November 2020

Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes

scientific article published on 09 January 2016

Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota

scientific article published on 17 July 2019

Erratum: The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation

scholarly article published in Obesity

Excitotoxic potential of the cyanotoxin β-methyl-amino-L-alanine (BMAA) in primary human neurons.

scientific article

Excitotoxicity in the pathogenesis of autism.

scientific article published on 13 October 2012

Expression of chemokines and their receptors in human and simian astrocytes: evidence for a central role of TNF alpha and IFN gamma in CXCR4 and CCR5 modulation

scientific article (publication date: March 2003)

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

scientific article published on 26 June 2015

Extracellular Vesicles Released by Glioblastoma Cells Stimulate Normal Astrocytes to Acquire a Tumor-Supportive Phenotype Via p53 and MYC Signaling Pathways

scientific article published on 23 October 2018

Fenugreek Seed Powder Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress, and Inflammation in a Rat Model of Alzheimer's Disease.

scientific article

Food and your mood: nutritional psychiatry

scientific article published on 30 June 2015

Fungal Neurotoxins and Sporadic Amyotrophic Lateral Sclerosis

scientific article published on 05 December 2018

Fungal-contaminated grass and well water and sporadic amyotrophic lateral sclerosis

scientific article published on 01 September 2019

Genetic Analysis of Tryptophan Metabolism Genes in Sporadic Amyotrophic Lateral Sclerosis

scientific article published on 14 June 2021

Genetic basis of hindlimb loss in a naturally occurring vertebrate model.

scientific article published on 18 February 2016

Gliotoxicity of the cyanotoxin, β-methyl-amino-L-alanine (BMAA).

scientific article published in January 2013

Global cellular responses to β-methyl-amino-L-alanine (BMAA) by olfactory ensheathing glial cells (OEC).

scientific article

Granulocyte macrophage colony stimulating factor stimulates in vitro proliferation of astrocytes derived from simian mature brains

scientific article published on 01 January 1996

Great expectations: Nutritional medicine as a mainstream in clinical psychiatry and weighing opportunities against risks

scientific article published on 23 January 2016

HIV, prospective memory, and cerebrospinal fluid concentrations of quinolinic acid and phosphorylated Tau

article

Human Tick-Borne Diseases in Australia

article

Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine-2,3-dioxygenase-involved mechanism(s).

scientific article published on 2 August 2017

IFN-beta1b induces kynurenine pathway metabolism in human macrophages: potential implications for multiple sclerosis treatment

scientific article published in December 2001

ISTRY 2013 Special Issue.

scientific article published on 21 July 2013

Identification of T-cell epitopes adjacent to neutralizing antigenic domains on the fusion protein of respiratory syncytial virus

scientific article

Impact of 27-hydroxycholesterol on amyloid-beta peptide production and ATP-binding cassette transporter expression in primary human neurons

scientific article

Implications for the kynurenine pathway and quinolinic acid in amyotrophic lateral sclerosis.

scientific article published on January 2005

Increased 3-hydroxykynurenine serum concentrations differentiate Alzheimer's disease patients from controls

scientific article

Increased mRNA expression of kynurenine pathway enzymes in human placentae exposed to bacterial endotoxin

scientific article published in January 2003

Increased markers of oxidative stress in autistic children of the Sultanate of Oman

scientific article published on 30 November 2011

Indoleamine 2,3 dioxygenase and quinolinic acid immunoreactivity in Alzheimer's disease hippocampus

scientific article

Induction of TDO2 and IDO2 in Liver by High-Fat Feeding in Mice: Discrepancies with Human Obesity

scientific article published on 21 July 2013

Inflammation and Parkinson's disease

scientific article published on 28 December 2011

Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression

scientific article published on 05 November 2019

Inflammation, immunology, stress and depression: a role for kynurenine metabolism in physical exercise and skeletal muscle

scientific article published on 2 February 2016

Interference of α-Synuclein Uptake by Monomeric β-Amyloid1-40 and Potential Core Acting Site of the Interference

scientific article published on 30 June 2016

Introductory editorial

scientific article published on 09 April 2008

Involvement of quinolinic acid in AIDS dementia complex

scientific article

Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis.

scientific article published on 2 June 2016

Involvement of the kynurenine pathway in human glioma pathophysiology

scientific article

Involvement of the kynurenine pathway in the pathogenesis of Parkinson's disease

scientific article published on 9 April 2016

Isolation, culture and characterization of astrocytes from adult monkey brains

scientific article

Keratin 14 Expression in Epithelial Progenitor Cells of the Developing Human Cornea

scientific article

Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms

scientific article published on 21 January 2019

Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD Concentration in Human Primary Astrocytes

scientific article published on 03 August 2010

Kynurenine Pathway Metabolites as Biomarkers for Amyotrophic Lateral Sclerosis

scientific article published on 20 September 2019

Kynurenine Pathway in Skin Cells: Implications for UV-Induced Skin Damage

scientific article published on 3 July 2012

Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

scientific article published in August 2001

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

scientific article published on 03 February 2017

Kynurenine pathway modulation reverses the experimental autoimmune encephalomyelitis mouse disease progression

scientific article published on 06 June 2020

Kynurenine-3-monooxygenase: a review of structure, mechanism, and inhibitors

scientific article (publication date: February 2016)

Kynurenines, Gender and Neuroinflammation; Showcase Schizophrenia

scientific article published on 24 June 2016

L-Serine-Mediated Neuroprotection Includes the Upregulation of the ER Stress Chaperone Protein Disulfide Isomerase (PDI).

scientific article published on 3 October 2017

Lead dysregulates serine/threonine protein phosphatases in human neurons.

scientific article

Long-term (15 mo) dietary supplementation with pomegranates from Oman attenuates cognitive and behavioral deficits in a transgenic mice model of Alzheimer's disease.

scientific article published on 25 June 2014

Long-term dietary supplementation of pomegranates, figs and dates alleviate neuroinflammation in a transgenic mouse model of Alzheimer's disease

scientific article

Loss of the Chr16p11.2 ASD candidate gene leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model

article

Low Molecular Weight Sulfated Chitosan: Neuroprotective Effect on Rotenone-Induced In Vitro Parkinson's Disease

scientific article published on 13 November 2018

Lycopene Pretreatment Ameliorates Acute Ethanol Induced NAD(+) Depletion in Human Astroglial Cells.

scientific article published on 14 May 2015

M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection

scientific article

Major developments in the design of inhibitors along the kynurenine pathway

scientific article published on 2 May 2017

Mapping NAD(+) metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence.

scientific article published on 17 December 2013

Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons.

scientific article

Mechanisms and Effects Posed by Neurotoxic Products of Cyanobacteria/Microbial Eukaryotes/Dinoflagellates in Algae Blooms: a Review.

scientific article

Mechanisms of L-Serine Neuroprotection in vitro Include ER Proteostasis Regulation

scientific article

Memantine Is Protective against Cytotoxicity Caused by Lead and Quinolinic Acid in Cultured Rat Embryonic Hippocampal Cells

scientific article published on 15 April 2019

Metallothionein treatment attenuates microglial activation and expression of neurotoxic quinolinic acid following traumatic brain injury

scientific article published on 20 March 2009

Microbiota Alterations in Alzheimer's Disease: Involvement of the Kynurenine Pathway and Inflammation

scientific article published on 14 May 2019

Microglia are both a source and target of extracellular cyclophilin A

scientific article published on 03 September 2019

Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification ⬇️

scientific article published on November 11, 2003

Microorganisms' Footprint in Neurodegenerative Diseases

scientific article published on 04 December 2018

Microorganisms, Tryptophan Metabolism, and Kynurenine Pathway: A Complex Interconnected Loop Influencing Human Health Status

scientific article published on 19 June 2019

Modulation of amyloid precursor protein processing by synthetic ceramide analogues.

scientific article published on 26 May 2010

Modulation of indoleamine-2,3-dioxygenase expression and activity by HIV-1 in human macrophages

scientific article published on 28 July 2009

Molecular characterization of beta-thalassemia mutations in Guadeloupe

scientific article published on 01 December 1996

Myxobacterial natural products: An under-valued source of products for drug discovery for neurological disorders.

scientific article published on 27 February 2018

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

scientific article published in August 2017

NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns.

scientific article published on January 2012

Naringenin Decreases α-Synuclein Expression and Neuroinflammation in MPTP-Induced Parkinson's Disease Model in Mice

scientific article published on 9 February 2018

Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes

scientific article published on 30 November 2017

Neurodegeneration and ageing in the HAART era.

scientific article published on 06 December 2008

Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation

scientific article

Neuroprotective Effect of Myxobacterial Extracts on Quinolinic Acid-Induced Toxicity in Primary Human Neurons

scientific article published on 28 September 2018

Neuroprotective effects of a variety of pomegranate juice extracts against MPTP-induced cytotoxicity and oxidative stress in human primary neurons.

scientific article published on 03 October 2013

Neuroprotective effects of hesperidin, a plant flavanone, on rotenone-induced oxidative stress and apoptosis in a cellular model for Parkinson's disease

scientific article published on 24 September 2013

Neuroprotective effects of rosmarinic acid on ciguatoxin in primary human neurons.

scientific article published on 5 October 2013

Neuroprotective role of Asiatic acid in aluminium chloride induced rat model of Alzheimer's disease.

scientific article

Neurotoxicity of the Cyanotoxin BMAA Through Axonal Degeneration and Intercellular Spreading.

scientific article published on 25 August 2017

New strategies in neuroprotection and neurorepair

scientific article published on 23 August 2011

Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor

scientific article published on 03 February 2019

Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target

scientific article published in December 2018

Obtention and characterization of primary astrocyte and microglial cultures from adult monkey brains

scientific article published in September 1997

Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation.

scientific article published on 3 March 2015

Perinatal Exposure to the Cyanotoxin β-N-Méthylamino-L-Alanine (BMAA) Results in Long-Lasting Behavioral Changes in Offspring-Potential Involvement of DNA Damage and Oxidative Stress.

scientific article published on 6 September 2017

Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's disease

scientific article published on 10 October 2019

Pomegranate from Oman Alleviates the Brain Oxidative Damage in Transgenic Mouse Model of Alzheimer's disease

scientific article

Possible role of tryptophan and melatonin in COVID-19

scientific article published on 21 August 2020

Post-Bariatric Surgery Changes in Quinolinic and Xanthurenic Acid Concentrations Are Associated with Glucose Homeostasis

scientific article

Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis

scientific article

Progesterone Alters Kynurenine Pathway Activation in IFN-γ-Activated Macrophages - Relevance for Neuroinflammatory Diseases.

scientific article published on 07 December 2016

Proinflammatory cytokine interferon-gamma increases induction of indoleamine 2,3-dioxygenase in monocytic cells primed with amyloid beta peptide 1-42: implications for the pathogenesis of Alzheimer's disease

scientific article

Promotion of cellular NAD(+) anabolism: therapeutic potential for oxidative stress in ageing and Alzheimer's disease.

scientific article published on May 2008

Protective Effect of Antioxidants on Neuronal Dysfunction and Plasticity in Huntington's Disease

scientific article published on 12 January 2017

Protective Effects of Antioxidants in Huntington's Disease: an Extensive Review

scientific article published on 11 January 2019

Protective Effects of Myxobacterial Extracts on Hydrogen Peroxide-induced Toxicity on Human Primary Astrocytes

scientific article published on 26 November 2018

Protein Nutrition in Autism

scientific article published on 01 January 2020

Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells

scientific article

Quinolinic acid in the pathogenesis of Alzheimer's disease.

scientific article

Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat.

scientific article published in February 2001

Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies

scientific article

Quinolinic acid up-regulates chemokine production and chemokine receptor expression in astrocytes.

scientific article

Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes

scientific article

Quinolinic acid, the inescapable neurotoxin ⬇️

scientific article published on March 27, 2012

Quinolinic acid: neurotoxicity.

scientific article

Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors

scientific article published in March 2009

Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases.

scientific article published on 16 March 2016

Recent rodent models for Alzheimer's disease: clinical implications and basic research

scientific article

Redox-active Cu(II)-Aβ causes substantial changes in axonal integrity in cultured cortical neurons in an oxidative-stress dependent manner

scientific article published on 9 June 2012

Retracted: Influences of Chronic Mild Stress Exposure on Motor, Non-Motor Impairments and Neurochemical Variables in Specific Brain Areas of MPTP/Probenecid Induced Neurotoxicity in Mice

retracted article

Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation

scientific article published on 22 November 2006

Role of NAD(+), Oxidative Stress, and Tryptophan Metabolism in Autism Spectrum Disorders

scientific article published on 21 July 2013

Role of Rho/ROCK signaling in the interaction of melanoma cells with the blood-brain barrier.

scientific article published on 23 October 2013

SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation

scientific article

Serotonin decreases HIV-1 replication in primary cultures of human macrophages through 5-HT(1A) receptors

scientific article published on 10 March 2008

Serotonin modulates HIV replication in primary culture of human macrophages: involvement of 5-HT(1A) sub-type receptors

scientific article

Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not Associated with Diseases Susceptibility

scientific article published on 12 February 2016

Serum nicotinamide adenine dinucleotide levels through disease course in multiple sclerosis

scientific article published on 21 August 2013

Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?

scientific article

Sleep Deprivation and Neurological Disorders

scientific article published on 23 November 2020

Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66.

scientific article published on 29 January 2016

Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes

scientific article published on 19 November 2019

Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease

scientific article published on 22 October 2019

Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma

scientific article published in Nature Communications

Synergistic induction of CXCL10 by interferon-gamma and lymphotoxin-alpha in astrocytes: Possible role in cerebral malaria.

scientific article published on 11 December 2015

Telmisartan Ameliorates Astroglial and Dopaminergic Functions in a Mouse Model of Chronic Parkinsonism

scientific article published on 13 July 2018

Tg2576 cortical neurons that express human Ab are susceptible to extracellular Aβ-induced, K+ efflux dependent neurodegeneration

scientific article

The Cyanotoxin and Non-protein Amino Acid β-Methylamino-L-Alanine (L-BMAA) in the Food Chain: Incorporation into Proteins and Its Impact on Human Health

scientific article published on 03 August 2019

The Involvement of Neuroinflammation and Kynurenine Pathway in Parkinson's Disease ⬇️

scientific article published on June 3, 2011

The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes

scientific article

The Plasma [Kynurenine]/[Tryptophan] Ratio and Indoleamine 2,3-Dioxygenase: Time for Appraisal

scientific article published on 21 August 2019

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease: A Mini Review.

scientific article published on 27 December 2016

The crossroads of neuroinflammation in infectious diseases: endothelial cells and astrocytes.

scientific article

The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions

scientific article published on 27 February 2015

The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress

scientific article published on 2 April 2013

The excitotoxin quinolinic acid induces tau phosphorylation in human neurons

scientific article published on 22 July 2009

The involvement of astrocytes and kynurenine pathway in Alzheimer's disease.

scientific article published on December 2007

The kynurenine pathway and inflammation in amyotrophic lateral sclerosis

scientific article published on 18 November 2009

The kynurenine pathway in brain tumor pathogenesis.

scientific article

The kynurenine pathway in stem cell biology.

scientific article published on 15 September 2013

The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation

article

The kynurenine pathway of tryptophan degradation is activated during osteoblastogenesis.

scientific article published in January 2015

The p38-MK2-HuR pathway potentiates EGFRvIII-IL-1β-driven IL-6 secretion in glioblastoma cells.

scientific article published on 4 August 2014

The potential for transition metal-mediated neurodegeneration in amyotrophic lateral sclerosis

scientific article

Time-dependent effect of oligomeric amyloid-β (1-42)-induced hippocampal neurodegeneration in rat model of Alzheimer's disease

scientific article published on 19 November 2018

Treatment of microglia with Anti-PrP monoclonal antibodies induces neuronal apoptosis in vitro

Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis

scientific article published on 8 June 2018

Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone

article

Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder ⬇️

scientific article published on June 10, 2010

Understanding the role of the kynurenine pathway in human breast cancer immunobiology

scientific article

Understanding the roles of the kynurenine pathway in multiple sclerosis progression.

scientific article published on 25 August 2010

Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts

scientific article

Vanillin Attenuated Behavioural Impairments, Neurochemical Deficts, Oxidative Stress and Apoptosis Against Rotenone Induced Rat Model of Parkinson's Disease.

scientific article published on 2 April 2016

p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells.

scientific article published on 19 April 2012

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