Search filters

List of works by David J. Brooks

(11)C-PIB PET in subjective cognitive impairment

scientific article published on 18 November 2009

11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

scientific article published on 26 February 2010

11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt–Jakob disease: Figure 1

scientific article published on 08 April 2011

18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease

scientific article published in March 2002

18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial

scientific article published on September 2010

1st Conference Clinical Trials on Alzheimer’s Disease September 17-18-19, 2008 School of Medecine Montpellier, France

article

A European multicentre PET study of fibrillar amyloid in Alzheimer's disease

scientific article

A H(2)(15)O positron emission tomography study on mental imagery of movement sequences--the effect of modulating sequence length and direction

scientific article published in October 2002

A PET study of voluntary movement in schizophrenic patients experiencing passivity phenomena (delusions of alien control).

scientific article

A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions

scientific article published on 24 September 2010

A comparison of the progression of early Parkinson's disease in patients started on ropinirole or L-dopa: an 18F-dopa PET study

scientific article

A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa

scientific article published in May 2000

A positron emission tomography study of frontal lobe function (verbal fluency) in amyotrophic lateral sclerosis

scientific article published on 01 May 1995

A proposal for a comprehensive grading of Parkinson's disease severity combining motor and non-motor assessments: meeting an unmet need

scientific article

A proton magnetic resonance spectroscopy study of the striatum and cerebral cortex in Parkinson's disease

scientific article

A six-month multicentre, double-blind, bromocriptine-controlled study of the safety and efficacy of ropinirole in the treatment of patients with Parkinson's disease not optimally controlled by L-dopa

scientific article published in April 2002

A study of medial pallidotomy for Parkinson's disease: clinical outcome, MRI location and complications

scientific article published in January 1998

A systematic comparison of kinetic modelling methods generating parametric maps for [(11)C]-(R)-PK11195.

scientific article

Abnormal Amyloid Load in Mild Cognitive Impairment: The Effect of Reducing the PiB-PET Threshold

scientific article published on 10 May 2019

Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS

scientific article

Absence of irradiation induced ischaemic temporal lobe damage in patients with pituitary tumours

scientific article published in January 1987

Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: a cross-validation study against amyloid positron emission tomography

scientific article

Acute HCV/HIV coinfection is associated with cognitive dysfunction and cerebral metabolite disturbance, but not increased microglial cell activation

scientific article

Adenosine 2A receptor availability in dyskinetic and nondyskinetic patients with Parkinson disease

scientific article (publication date: 24 May 2011)

Advances in the understanding of early Huntington's disease using the functional imaging techniques of PET and SPET.

scientific article

Age at onset and Parkinson disease phenotype.

scientific article

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease

scientific article published on 31 October 2019

Alterations in opioid receptor binding in Parkinson's disease patients with levodopa-induced dyskinesias

scientific article published on November 1997

Amyloid load and cerebral atrophy in Alzheimer's disease: an 11C-PIB positron emission tomography study

scientific article published in July 2006

Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography

scientific article published on 24 July 2008

Amyloid pathology and axonal injury after brain trauma.

scientific article published on 3 February 2016

Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study

scientific article published on 25 October 2006

Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias

scientific article published on 01 November 2020

Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis

scientific article

An [18F]dopa-PET and clinical study of the rate of progression in Parkinson's disease

scientific article published in April 1996

An early and late peak in microglial activation in Alzheimer's disease trajectory

scientific article published on 24 January 2017

An exploratory efficacy study of the amyloid imaging agent [(18)F]flutemetamol in Japanese Subjects

scientific article

An imaging study of parkinsonism among African-Caribbean and Indian London communities

scientific article published in November 2002

An open-label, positron emission tomography study to assess adenosine A2A brain receptor occupancy of vipadenant (BIIB014) at steady-state levels in healthy male volunteers

scientific article published on March 2010

Apathy blunts neural response to money in Parkinson's disease

scientific article

Assessment of Parkinson's disease with imaging.

scientific article published on January 2007

Assessment of neuroinflammation in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study

scientific article

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

scientific article published on 29 November 2017

Association of abnormal cerebellar activation with motor learning difficulties in dyslexic adults

scientific article published in May 1999

Attenuation of dopamine-induced GABA release in problem gamblers

scientific article published on 20 February 2019

Atypical parkinsonism in Afro-Caribbean and Indian origin immigrants to the UK.

scientific article

Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease

scientific article published in February 2012

Bad news for neuroprotective therapies in PD?

scientific article published in January 2013

Balancing bias, reliability, noise properties and the need for parametric maps in quantitative ligand PET: [(11)C]diprenorphine test-retest data

scientific article

Benefits of putaminal GDNF infusion in Parkinson disease are maintained after GDNF cessation

scientific article published on 14 August 2013

Benzodiazepine-GABA(A) receptor binding is very low in dysembryoplastic neuroepithelial tumor: a PET study

scientific article published in October 2001

Benzodiazepine-GABAA Receptor Binding During Absence Seizures

scientific article published on 01 June 1995

Benzodiazepine-GABAA Receptors in Idiopathic Generalized Epilepsy Measured with [11C]Flumazenil and Positron Emission Tomography

scientific article published on 01 February 1995

Binary classification of ¹⁸F-flutemetamol PET using machine learning: comparison with visual reads and structural MRI.

scientific article published on 14 September 2012

Botulinum toxin does not reverse the cortical dysfunction associated with writer's cramp. A PET study

scientific article

Brain dopamine response in human opioid addiction.

scientific article

Brain inflammation accompanies amyloid in the majority of mild cognitive impairment cases due to Alzheimer’s disease

scientific article (publication date: 28 May 2017)

Brain monoamine systems in multiple system atrophy: a positron emission tomography study.

scientific article published on 12 January 2012

Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: an [11C]diprenorphine PET study.

scientific article

Brain opioid receptor binding in early abstinence from opioid dependence: positron emission tomography study.

scientific article

Can imaging separate multiple system atrophy from Parkinson's disease?

scientific article published on January 1, 2012

Can target-to-pons ratio be used as a reliable method for the analysis of [11C]PIB brain scans?

scientific article published on 27 January 2012

Carbon-11-Pittsburgh compound B positron emission tomography imaging of amyloid deposition in presenilin 1 mutation carriers

scientific article published on 16 November 2010

Cardiovascular effects of methamphetamine in Parkinson's disease patients.

scientific article published in March 2004

Carotid body autotransplantation in Parkinson disease: a clinical and positron emission tomography study.

scientific article

Central benzodiazepine/gamma-aminobutyric acid A receptors in idiopathic generalized epilepsy: an [11C]flumazenil positron emission tomography study

scientific article published in October 1997

Cerebral activation in malformations of cortical development.

scientific article published in July 1998

Cerebral benzodiazepine receptors in hippocampal sclerosis. An objective in vivo analysis

scientific article published in October 1996

Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study.

scientific article

Cerebral glucose metabolism in corticobasal degeneration: comparison with progressive supranuclear palsy and normal controls

scientific article published in September 1997

Cerebral microglial activation in patients with hepatitis C: in vivo evidence of neuroinflammation.

scientific article

Characterisation of the contribution of the GABA-benzodiazepine α1 receptor subtype to [(11)C]Ro15-4513 PET images

scientific article published on 4 January 2012

Characterization of dopaminergic dysfunction in familial progressive supranuclear palsy: an 18F-dopa PET study

scientific article published on 8 August 2006

Characterizing mild cognitive impairment in incident Parkinson disease: the ICICLE-PD study

scientific article published on 20 December 2013

Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder

scientific article published on 22 December 2019

Chorea associated with thyroxine replacement therapy

scientific article published in December 2005

Chronic exposure to dopamine agonists affects the integrity of striatal D2 receptors in Parkinson's patients

scientific article published on 24 August 2017

Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: an 18F-dopa PET study

scientific article

Clinical correlates of levodopa-induced dopamine release in Parkinson disease: a PET study

scientific article published on November 2006

Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease.

scientific article published on 23 July 2015

Clinical implications of early caudate dysfunction in Parkinson's disease

scientific article published on 11 May 2019

Cognitive and motor effects of dopaminergic medication withdrawal in Parkinson's disease

scientific article published in January 2004

Cognitive deficits and striato-frontal dopamine release in Parkinson's disease.

scientific article

Cognitive deficits in non-demented amyotrophic lateral sclerosis patients: a neuropsychological investigation

scientific article published in May 1995

Combination of biomarkers: PET [18F]flutemetamol imaging and structural MRI in dementia and mild cognitive impairment

scientific article published in February 2012

Combined pedunculopontine-subthalamic stimulation in Parkinson disease.

scientific article

Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET.

scientific article published on 20 December 2012

Compulsive drug use linked to sensitized ventral striatal dopamine transmission

scientific article published in May 2006

Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter

scientific article published on 01 October 2019

Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study.

scientific article

Correction: A Proposal for a Comprehensive Grading of Parkinson's Disease Severity Combining Motor and Non-Motor Assessments: Meeting an Unmet Need

scientific article published on 19 February 2016

Correlates of local cerebral blood flow (CBF) in normal pressure hydrocephalus patients before and after shunting--A retrospective analysis of [(15)O]H(2)O PET-CBF studies in 65 patients

scientific article published on 11 February 2008

Correlating rates of cerebral atrophy in Parkinson's disease with measures of cognitive decline

scientific article published in January 2001

Cortical 5-HT1A receptor binding in patients with homozygous D90A SOD1 vs sporadic ALS.

scientific article

Cortical control of movement in Huntington's disease. A PET activation study

scientific article published in September 1997

Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers

scientific article published on 22 October 2009

Cortical hypermetabolism in MCI subjects: a compensatory mechanism?

scientific article published on 30 September 2014

Cortical involvement in four cases of primary lateral sclerosis using [(11)C]-flumazenil PET.

scientific article published on 9 February 2007

Decreased intestinal acetylcholinesterase in early Parkinson disease: An 11C-donepezil PET study

scientific article published on 18 January 2017

Decreased noradrenaline transporter density in the motor cortex of Parkinson's disease patients

scientific article published on 24 May 2018

Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts

scientific article published on 01 November 2000

Delayed recovery of movement‐related cortical function in Parkinson's disease after striatal dopaminergic grafts

scholarly article by Paola Piccini et al published November 2000 in Annals of Neurology

Depression in Parkinsonʼs disease

scientific article published on 01 August 2001

Depressive symptoms in PD correlate with higher 5-HTT binding in raphe and limbic structures

scientific article published on November 2010

Development of dyskinesias in a 5-year trial of ropinirole andL-dopa

article

Diffusion-weighted imaging and its relationship to microglial activation in parkinsonian syndromes

scientific article

Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease

scientific article (publication date: May 2003)

Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: studies with [11C]flumazenil PET.

scientific article

Distributed neural actions of anti-parkinsonian therapies as revealed by PET.

scientific article

Does Microglial Activation Influence Hippocampal Volume and Neuronal Function in Alzheimer's Disease and Parkinson's Disease Dementia?

scientific article published on 5 March 2016

Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study

scientific article published on 11 June 2018

Dopamine agonists and neuroprotection in parkinson's disease

scientific article published on 01 September 1998

Dopamine agonists: their role in the treatment of Parkinson's disease

scientific article published in June 2000

Dopamine release during sequential finger movements in health and Parkinson's disease: a PET study

scientific article published in February 2003

Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient

scientific article

Dopaminergic action beyond its effects on motor function: imaging studies.

scientific article published on August 2006

Dopaminergic function in familial Parkinson's disease: A clinical and18F-dopa positron emission tomography study

scholarly article by Paola Piccini et al published February 1997 in Annals of Neurology

Dynamic 11C-PiB PET shows cerebrospinal fluid flow alterations in Alzheimer’s disease and multiple sclerosis

scientific article published on 08 March 2019

Dyskinesia in the elderly presenting as respiratory disorder.

scientific article published on November 1989

Dyskinesias following neural transplantation in Parkinson's disease

scientific article published in July 2002

Effect of L-dopa and 6-hydroxydopamine lesioning on [11C]raclopride binding in rat striatum, quantified using PET

scientific article published on 01 September 1995

Endogenous dopamine release after pharmacological challenges in Parkinson's disease.

scientific article published in May 2003

Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study)

scientific article published on 03 April 2019

Evaluation of [11C]RTI-121 as a selective radioligand for PET studies of the dopamine transporter.

scientific article published in April 1996

Evaluation of [4-O-methyl-(11)C]KW-6002 as a potential PET ligand for mapping central adenosine A(2A) receptors in rats

scientific article published in December 2001

Evaluation of the noradrenergic system in Parkinson's disease: an 11C-MeNER PET and neuromelanin MRI study.

scientific article published on 18 December 2017

Evidence for lateral premotor and parietal overactivity in Parkinson's disease during sequential and bimanual movements. A PET study

scientific article published in June 1997

Evidence of dopamine dysfunction in the hypothalamus of patients with Parkinson's disease: an in vivo 11C-raclopride PET study.

scientific article published on 6 August 2008

Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study.

scientific article published in April 2004

Exacerbation of postural tremor with emergence of parkinsonism after treatment with neuroleptic drugs

scientific article

Examining Braak's hypothesis by imaging Parkinson's disease.

scientific article published on January 2010

Exogenous dopamine reduces GABA receptor availability in the human brain

scientific article published on 5 May 2016

Expanding CEP290 mutational spectrum in ciliopathies

scientific article published on 01 October 2009

Extrastriatal monoamine neuron function in Parkinson's disease: an 18F-dopa PET study.

scientific article published on 26 September 2007

Extrastriatal monoaminergic dysfunction and enhanced microglial activation in idiopathic rapid eye movement sleep behaviour disorder.

scientific article published on 6 March 2018

F26. Automated chin EMG analysis for quantification of REM sleep without atonia

Factors affecting the clinical outcome after neural transplantation in Parkinson's disease

scientific article

Fatigue in Parkinson's disease is linked to striatal and limbic serotonergic dysfunction.

scientific article published on 30 September 2010

Five-year efficacy and safety of levodopa/DDCI and entacapone in patients with Parkinson's disease

scientific article

Flutriciclamide (18F-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein.

scientific article published on 3 June 2016

Focal cortical release of endogenous opioids during reading-induced seizures

scientific article published in September 1998

Frontal lobe dysfunction in amyotrophic lateral sclerosis. A PET study

scientific article published in December 1996

Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease A 3D [(18)F]dopa-PET study

scientific article published in September 1999

Functional imaging studies on dopamine and motor control

scientific article published on January 1, 2001

GABA-benzodiazepine receptor function in alcohol dependence: a combined 11C-flumazenil PET and pharmacodynamic study

scientific article published on 28 April 2005

GABAergic dysfunction in essential tremor: an 11C-flumazenil PET study

scientific article published on 16 June 2010

GDNF in treatment of Parkinson's disease: response to editorial

article

Gender-related differences in the burden of non-motor symptoms in Parkinson's disease

scientific article published on 12 January 2012

Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study

scientific article

Genetic linkage of autosomal dominant progressive supranuclear palsy to 1q31.1.

scientific article published in May 2005

Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain

scientific article published in July 2005

Glutamate NMDA receptor dysregulation in Parkinson's disease with dyskinesias.

scientific article

Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio

scientific article published on 24 May 2011

Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease?

scientific article published on 22 July 2015

Grey and white matter flumazenil binding in neocortical epilepsy with normal MRI. A PET study of 44 patients

scientific article

Health-related quality of life following bilateral intrastriatal transplantation in Parkinson's disease

scientific article

Health-related quality of life in early Parkinson's disease: the impact of nonmotor symptoms

scientific article published on 7 October 2013

How far are we in understanding the cause of Parkinson's disease?

scientific article published on January 1997

Huntington's disease progression. PET and clinical observations.

scientific article

Hypothalamic volume loss is associated with reduced melatonin output in Parkinson's disease

scientific article published on 12 March 2016

Imaging Approaches to Parkinson Disease

scientific article

Imaging Dopamine Transporters in Parkinson‘s Disease

scientific article published on October 1, 2010

Imaging Parkinson's disease

scientific article published on 01 January 2007

Imaging Parkinson's disease below the neck.

scientific article

Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with 11C-donepezil PET.

scientific article published on 23 December 2014

Imaging biomarkers in Parkinson's disease.

scientific article

Imaging biomarkers in tauopathies.

scientific article published on 14 August 2015

Imaging end points for monitoring neuroprotection in Parkinson's disease.

scientific article

Imaging markers for Alzheimer disease: which vs how

scientific article

Imaging microglial activation in Huntington's disease

scientific article

Imaging neurodegeneration in Parkinson's disease

scientific article

Imaging neuroinflammation in Alzheimer's disease and other dementias: Recent advances and future directions.

scientific article

Imaging non-dopaminergic function in Parkinson's disease.

scientific article published on July 2007

Imaging non-motor aspects of Parkinson's disease.

scientific article published on January 2010

Imaging of genetic and degenerative disorders primarily causing Parkinsonism.

scientific article

Imaging studies in drug development: Parkinson's disease

article

Imaging synucleinopathies.

scientific article published on 16 February 2016

Imaging the role of dopamine in health and disease Parkinson's disease as a lesion model

scientific article published in October 2006

Impaired recognition of facial expressions of anger in Parkinson's disease patients acutely withdrawn from dopamine replacement therapy

scientific article published on 15 June 2006

Implementation and application of a brain template for multiple volumes of interest

article

In Response to Letter from Fregonara et al. 2019

scientific article published on 01 February 2020

In Vivo cortical tau in Parkinson's disease using 18F-AV-1451 positron emission tomography.

scientific article published on 3 March 2017

In vivo [11C]flumazenil-PET correlates with ex vivo [3H]flumazenil autoradiography in hippocampal sclerosis.

scientific article published in May 1998

In vivo assessment of brain monoamine systems in parkin gene carriers: a PET study

scientific article published on 4 January 2010

In vivo imaging of human acetylcholinesterase density in peripheral organs using 11C-donepezil: dosimetry, biodistribution, and kinetic analyses

scientific article published on 16 October 2014

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in corticobasal degeneration

scientific article

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

scientific article published on 21 September 2005

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in progressive supranuclear palsy

scientific article published on January 2006

In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET.

scientific article

In vivo quantification of glial activation in minipigs overexpressing human α-synuclein

scientific article published on 12 August 2018

In-vivo measurement of activated microglia in dementia

scientific article published in August 2001

Increased activation of frontal areas during arm movement in idiopathic torsion dystonia

scientific article published in March 1998

Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART.

scientific article

Inflammation after trauma: microglial activation and traumatic brain injury

scientific article published on 27 June 2011

Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia.

scientific article published on 16 September 2014

Initial evaluation of 18F-GE-179, a putative PET Tracer for activated N-methyl D-aspartate receptors

scientific article published on 13 February 2014

Intra- and inter-network functional alterations in Parkinson's disease with mild cognitive impairment.

scientific article published on 13 January 2017

Investigating expectation and reward in human opioid addiction with [(11) C]raclopride PET

scientific article

Investigation of the opioid system in absence seizures with positron emission tomography.

scientific article

Kinetic analysis of the translocator protein positron emission tomography ligand [18F]GE-180 in the human brain

scientific article published on 28 June 2016

L-dihydroxyphenylalanine and its decarboxylase: new ideas on their neuroregulatory roles.

scientific article published on May 1995

Lateralisation of striatal function: evidence from 18F-dopa PET in Parkinson's disease.

scientific article

Long-term changes of GABAergic function in the sensorimotor cortex of amputees

scientific article published on 01 August 2000

Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease.

scientific article published on 20 March 2008

Longitudinal diffusion tensor imaging changes in early Parkinson’s disease: ICICLE-PD study

scientific article published on 25 April 2018

Longitudinal influence of microglial activation and amyloid on neuronal function in Alzheimer's disease.

scientific article published on 27 October 2015

Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease

scientific article

Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer's disease

scientific article published on 02 January 2020

MAO-B Inhibitors Do Not Block In Vivo Flortaucipir([(18)F]-AV-1451) Binding.

scientific article published on 10 November 2017

Mapping the network for planning: a correlational PET activation study with the Tower of London task

scientific article

Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab

scientific article published on 10 October 2011

Methodology for Statistical Parametric Mapping of [ 18 F]Fluorodopa Uptake Rate Using Three-Dimensional PET 1 1Transcripts of the BRAINPET97 discussion of this chapter can be found in Section VIII

Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

scientific article

Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia

scientific article published on 6 December 2012

Microglial activation and amyloid deposition in mild cognitive impairment: a PET study

scientific article

Microglial activation correlates in vivo with both tau and amyloid in Alzheimer’s disease

scientific article published on 01 September 2018

Microglial activation correlates with severity in Huntington disease: a clinical and PET study.

scientific article published in June 2006

Microglial activation in early Alzheimer trajectory is associated with higher gray matter volume

scientific article published on 22 February 2019

Microglial activation in presymptomatic Huntington's disease gene carriers

scientific article

Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: a multimodal imaging study

scientific article published in February 2011

Milestones in neuroimaging

scientific article published on May 1, 2011

Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial).

scientific article published in January 2010

Molecular imaging of dopamine transporters

scientific article

Monoamine neuron innervation of the normal human brain: an 18F-DOPA PET study.

scientific article published in August 2003

Motor Disturbance and Brain Functional Imaging in Parkinson's Disease

scientific article published on January 1, 1997

Motor function in a patient with bilateral lesions of the globus pallidus

scientific article published on 01 November 1995

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data

scientific article

NMDA receptor binding in focal epilepsies

scientific article

Neuroimaging in Parkinson's disease

scientific article published on 01 April 2004

Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: an (11C)-flumazenil PET study

scientific article

New developments of brain imaging for Parkinson's disease and related disorders.

scientific article

Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and Parkin-linked Parkinson's disease

scientific article

Nigrostriatal dysfunction in homozygous and heterozygous parkin gene carriers: an 18F-dopa PET progression study

scientific article published in November 2009

Nigrostriatal proteasome inhibition impairs dopamine neurotransmission and motor function in minipigs

scientific article published on 8 February 2018

Non-invasive in vivo imaging of transplant function.

scientific article

Novel reference region model reveals increased microglial and reduced vascular binding of 11C-(R)-PK11195 in patients with Alzheimer's disease

scientific article published on 16 July 2008

Observations on muscle activity in REM sleep behavior disorder assessed with a semi-automated scoring algorithm

scientific article published on 28 December 2017

Opioid binding in DYT1 primary torsion dystonia: an 11C-diprenorphine PET study

scientific article published in December 2004

Orolingual dystonia with "tip of the tongue" geste

scientific article published in July 1994

Overactive prefrontal and underactive motor cortical areas in idiopathic dystonia

scientific article published on 01 March 1995

P449 The role of rostral supplementary motor area and basal ganglia in motor sequence control

Pallidotomy in Parkinson's disease increases supplementary motor area and prefrontal activation during performance of volitional movements an H2(15)O PET study

scientific article published in August 1997

Parametric mapping using spectral analysis for 11C-PBR28 PET reveals neuroinflammation in mild cognitive impairment subjects

scientific article published on 9 March 2018

Parkinson's disease--the debate on the clinical phenomenology, aetiology, pathology and pathogenesis

scientific article published on January 2013

Parkinsonism associated with acute intracranial hematomas: an [18F]dopa positron-emission tomography study

scientific article

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

scientific article published in September 2017

Periventricular white matter flumazenil binding and postoperative outcome in hippocampal sclerosis

scientific article published in June 2005

Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease.

scientific article published on 17 July 2009

Plasticity of the nigropallidal pathway in Parkinson's disease.

scientific article

Positron emission tomography analysis of [11C]KW-6002 binding to human and rat adenosine A2A receptors in the brain

scientific article published in September 2008

Positron emission tomography and single-photon emission computed tomography in central nervous system drug development.

scientific article

Positron emission tomography imaging of transplant function.

scientific article

Positron emission tomography in the study of cerebral tumours

scientific article published on January 1984

Positron emission tomography studies of neurotransmitter systems

scientific article published in December 1990

Positron emission tomography studies on the dopaminergic system and striatal opioid binding in the olivopontocerebellar atrophy variant of multiple system atrophy

scientific article

Pre-synaptic and post-synaptic dopaminergic system in human brain

scientific article published in July 1984

Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis

scientific article published in May 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

scientific article published on May 2015

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

scientific article published on 27 March 2018

Probabilistic classification learning with corrective feedback is associated with in vivo striatal dopamine release in the ventral striatum, while learning without feedback is not

scientific article

Progression of monoaminergic dysfunction in Parkinson's disease: a longitudinal 18F-dopa PET study.

scientific article published on 17 March 2011

Progression of nonmotor symptoms in subgroups of patients with non-dopamine-deficient Parkinsonism.

scientific article published on 11 February 2016

Progression of tremor in early stages of Parkinson's disease: a clinical and neuroimaging study

scientific article

Progressive loss of raphe nuclei serotonin transporter in early Parkinson's disease: A longitudinal 123I-FP-CIT SPECT study

scientific article published on 05 April 2019

Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.

scientific article published in May 2003

Proton magnetic resonance spectroscopy in Huntington's disease: evidence in favour of the glutamate excitotoxic theory

scientific article published in March 1996

Quantification of opioid receptor availability following spontaneous epileptic seizures: correction of [11C]diprenorphine PET data for the partial-volume effect

scientific article

Quantitation of carbon-11-labeled raclopride in rat striatum using positron emission tomography

scientific article published in September 1992

Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease

scientific article published on March 2006

Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial

scientific article

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

scientific article published on 13 December 2017

Red nuclear and cerebellar but no olivary activation associated with essential tremor: A positron emission tomoraphic study

scientific article published on 01 October 1994

Reference Region Automatic Extraction in Dynamic [11C]PIB

scientific article published on 07 August 2013

Regional changes in [18F]dopa metabolism in the striatum in Parkinson's disease

scientific article published in December 1996

Regional hippocampal [11C]flumazenil PET in temporal lobe epilepsy with unilateral and bilateral hippocampal sclerosis

scientific article published in October 1997

Relationship between weight, levodopa and dyskinesia: the significance of levodopa dose per kilogram body weight

scientific article

Reorganization of cortical blood flow and transcranial magnetic stimulation maps in human subjects after upper limb amputation

article by J. J. Kew et al published November 1994 in Journal of Neurophysiology

Reply: Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and parkin-linked Parkinson's disease

scholarly article by Michele Hu et al published 2007 in Movement Disorders

Research goals in progressive supranuclear palsy

Research goals in progressive supranuclear palsy. First International Brainstorming Conference on PSP

scientific article published on 01 May 2000

Resting regional cerebral glucose metabolism in advanced Parkinson's disease studied in the off and on conditions with [(18)F]FDG-PET.

scientific article published in November 2001

Resting tremor in Parkinson disease: is the pallidum to blame?

scientific article published in February 2011

Restoration of thalamocortical activity after posteroventral pallidotomy in Parkinson's disease

scientific article published in The Lancet

Reward processing in health and Parkinson's disease: neural organization and reorganization

scientific article published in January 2004

Ropinirole in the treatment of early Parkinson's disease: A 6-month interim report of a 5-year levodopa-controlled study

scientific article published on 01 January 1998

Ropinirole versus bromocriptine in the treatment of early Parkinson's disease: A 6-month interim report of a 3-year study

scientific article published on 01 January 1998

STN stimulation alters pallidal-frontal coupling during response selection under competition

scientific article published on 22 November 2006

Safety and feasibility of autologous bone marrow cellular therapy in relapsing-progressive multiple sclerosis.

scientific article published on 5 May 2010

Second consensus statement on the diagnosis of multiple system atrophy

scientific article

Sequential bilateral transplantation in Parkinson's disease: effects of the second graft

scientific article published in June 1999

Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson's disease patients

scientific article published on 17 February 2014

Serotonergic mediated body mass index changes in Parkinson's disease

scientific article published on 23 May 2011

Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants

scientific article published in June 2010

Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts

scientific article

Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease

scientific article published in July 1997

Simplifying [18F]GE-179 PET: are both arterial blood sampling and 90-min acquisitions essential?

scientific article

Sleep problems and hypothalamic dopamine D3 receptor availability in Parkinson disease

scientific article published on 2 November 2016

Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study

scientific article published in July 2003

Staging of serotonergic dysfunction in Parkinson's disease: an in vivo 11C-DASB PET study

scientific article published on 31 May 2010

Statistical neuroanatomy of the human inferior frontal gyrus and probabilistic atlas in a standard stereotaxic space

scientific article published in January 2007

Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson's disease

scientific article

Stereotactic thalamotomy in tremor-dominant Parkinson's disease: an H2(15)O PET motor activation study

scientific article published in January 1997

Strategies for the generation of parametric images of [11C]PIB with plasma input functions considering discriminations and reproducibility.

scientific article published on 8 July 2009

Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease

scientific article published in July 1996

Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism

scientific article published on 16 April 2004

Studies on regional cerebral oxygen utilisation and cognitive function in multiple sclerosis.

scientific article

Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients.

scientific article published on 17 November 2016

Tau Aggregation Correlates with Amyloid Deposition in Both Mild Cognitive Impairment and Alzheimer's Disease Subjects

scientific article published on 01 January 2019

Tau Tangles in Parkinson's Disease: A 2-Year Follow-Up Flortaucipir PET Study

scientific article published on 01 January 2020

Technical aspects of amyloid imaging for Alzheimer's disease

scientific article published on 31 August 2011

Technology insight: imaging neurodegeneration in Parkinson's disease.

scientific article published on April 2008

Temporally-specific retrograde amnesia in two cases of discrete bilateral hippocampal pathology

scientific article published in January 1999

Test-retest reproducibility of cannabinoid-receptor type 1 availability quantified with the PET ligand [¹¹C]MePPEP.

scientific article

The Effect of 40-Hz Light Therapy on Amyloid Load in Patients with Prodromal and Clinical Alzheimer's Disease

scientific article published on 30 July 2018

The catechol-O-methyltransferase (COMT) inhibitor entacapone enhances the pharmacokinetic and clinical response to Sinemet CR in Parkinson's disease

scientific article

The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study

scientific article published in August 2012

The clinical safety, biodistribution and internal radiation dosimetry of flutemetamol (¹⁸F) injection in healthy Japanese adult volunteers.

scientific article published on 5 June 2015

The effect of movement frequency on cerebral activation: a positron emission tomography study

scientific article

The effect of the nitric oxide donor glyceryl trinitrate on global and regional cerebral blood flow in man

scientific article published on 01 September 2000

The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. II. Correlation between positron emission tomography and reaching behaviour.

scientific article published in August 1997

The human premotor cortex is 'mirror' only for biological actions.

scientific article

The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease

scientific article (publication date: June 2013)

The prognostic value of amyloid imaging.

scientific article published on 11 April 2012

The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease

scientific article published in July 1998

The risk of exaggerated risk aversion-a life and death struggle for molecular imaging

scientific article published on October 2009

The role of inheritance in sporadic Parkinson's disease: evidence from a longitudinal study of dopaminergic function in twins

scientific article published in May 1999

The role of opioids in restless legs syndrome: an [11C]diprenorphine PET study

scientific article

The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study

scientific article published on 6 January 2015

The role of structural and functional imaging in parkinsonian states with a description of PET technology

scientific article

The spectrum of nonmotor symptoms in early Parkinson disease

scientific article published on January 2013

The usefulness of functional imaging in movement disorders: an illustrative case

scientific article

Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe

scientific article

Treatment of end-of-dose wearing-off in parkinson's disease: stalevo (levodopa/carbidopa/entacapone) and levodopa/DDCI given in combination with Comtess/Comtan (entacapone) provide equivalent improvements in symptom control superior to that of tradi

scientific article published on 20 June 2005

Tremor associated with benign IgM paraproteinaemic neuropathy

scientific article published on 01 June 1996

Unilateral pallidotomy for Parkinson's disease: results after more than 1 year

scientific article

Upregulation of dopamine D2 receptors in dopaminergic drug-naive patients with Parkin gene mutations

scientific article published in June 2006

Upregulation of opioid receptor binding following spontaneous epileptic seizures

scientific article

Using [(11)C]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism

scientific article

Using [11C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: clinical and preclinical studies

scientific article published on 3 September 2004

Validation of an electronic image reader training programme for interpretation of [18F]flutemetamol β-amyloid PET brain images.

scientific article published on 14 December 2016

Validation of the freezing of gait questionnaire in patients with Parkinson's disease

scientific article published in April 2009

Ventral Striatal Dopamine Synthesis Capacity Predicts Financial Extravagance in Parkinson’s Disease

scientific article published on February 27, 2013

Ventral striatal dopamine synthesis capacity is associated with individual differences in behavioral disinhibition.

scientific article published on 14 March 2014

Volumes, spatial extents and a probabilistic atlas of the human basal ganglia and thalamus

scientific article published on 14 June 2007

Volumetric cortical loss in sporadic and familial amyotrophic lateral sclerosis

What can biomarkers tell us about cognition in Parkinson's disease?

scientific article published on April 2014

Whole-body biodistribution and radiation dosimetry of 18F-GE067: a radioligand for in vivo brain amyloid imaging

scientific article published on 16 April 2009

[11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS.

scientific article published on 2 February 2005

[11C]Flumazenil PET in temporal lobe epilepsy: do we need an arterial input function or kinetic modeling?

scientific article published on 20 June 2007

[123I]AM281 single-photon emission computed tomography imaging of central cannabinoid CB1 receptors before and after Delta9-tetrahydrocannabinol therapy and whole-body scanning for assessment of radiation dose in tourette patients.

scientific article published in May 2004

[¹⁸F]FDOPA uptake in the raphe nuclei complex reflects serotonin transporter availability. A combined [¹⁸F]FDOPA and [¹¹C]DASB PET study in Parkinson's disease

scientific article