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List of works by Lars Klimaschewski

A novel DRAK inhibitor, SC82510, promotes axon branching of adult sensory neurons in vitro

scientific article

Adult neurogenesis in a psychopathological mouse model of trait anxiety and comorbid depression-like behavior: effect of antidepressants.

scientific article published on 12 November 2009

Albumin-based nanoparticles as magnetic resonance contrast agents: I. Concept, first syntheses and characterisation

scientific article published on 20 February 2010

Analysis of the fibroblast growth factor system reveals alterations in a mouse model of spinal muscular atrophy

scientific article

Antisense oligodeoxynucleotides to bax mRNA promote survival of rat sympathetic neurons in culture

scientific article

Anxiety- rather than depression-like behavior is associated with adult neurogenesis in a female mouse model of higher trait anxiety- and comorbid depression-like behavior ⬇️

scientific article published on October 16, 2012

Axotomy-induced changes in the chemical coding pattern of colon projecting calbindin-positive neurons in the inferior mesenteric ganglia of the pig.

scientific article published on 02 April 2013

Basic fibroblast growth factor isoforms promote axonal elongation and branching of adult sensory neurons in vitro

scientific article published in January 2004

Biolistic transfection and morphological analysis of cultured sympathetic neurons

scientific article published in January 2002

C3 exoenzyme lacks effects on peripheral axon regenerationin vivo

scientific article published on 01 March 2013

C3 peptide enhances recovery from spinal cord injury by improved regenerative growth of descending fiber tracts

scientific article published on 20 April 2010

Characterization of afferent and efferent galanin-containing nerve fibres in the porcine ovary

scientific article published on 01 January 2002

Chemical codes of sensory neurons innervating the guinea-pig adrenal gland

scientific article published in January 1995

Cisatracurium, but not mivacurium, inhibits survival and axonal growth of neonatal and adult rat peripheral neurons in vitro

scientific article published in July 2004

Constitutively expressed catalytic proteasomal subunits are up-regulated during neuronal differentiation and required for axon initiation, elongation and maintenance

scientific article

Differential display PCR reveals induction of immediate early genes by vasoactive intestinal peptide in PC12 cells

scientific article published on 01 December 1998

Differential neurotoxicity of tricyclic antidepressants and novel derivatives in vitro in a dorsal root ganglion cell culture model

scientific article published on 17 April 2007

Endocytosis and Transport of Growth Factor Receptors in Peripheral Axon Regeneration: Novel Lessons from Neurons Expressing Lysine-Deficient FGF Receptor Type 1 in vitro

scientific article published on 22 April 2019

Enhanced axon outgrowth and improved long-distance axon regeneration in sprouty2 deficient mice

scientific article published on 14 August 2014

Expression of basic fibroblast growth factor isoforms in postmitotic sympathetic neurons: synthesis, intracellular localization and involvement in karyokinesis

scientific article published in January 2004

Expression of nicotinic acetylcholine receptors in the rat superior cervical ganglion on mRNA and protein level

scientific article published on 01 November 1994

Expression pattern of candidate cell death effector proteins Bax, Bcl-2, Bcl-X, and c-Jun in sensory and motor neurons following sciatic nerve transection in the rat.

scientific article

From birth till death: neurogenesis, cell cycle, and neurodegeneration.

scientific article published on December 2009

Genetically modified stem cells for the treatment of neurological diseases

scientific article published in January 2012

Glial cell death induced by overexpression of alpha-synuclein

scientific article

Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling.

scientific article published on September 2000

Identification of voltage-gated K(+) channel beta 2 (Kvβ2) subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 channel (TRPV1).

scientific article published on 11 September 2013

Imaging axon regeneration within synthetic nerve conduits

scientific article published on 12 July 2019

Immunohistochemical correlation of human adrenal nerve fibres and thoracic dorsal root neurons with special reference to substance P

scientific article published on 01 September 1995

Immunohistochemical evidence from co-localization and denervation studies for four types of substance P-containing nervous structures in the rat superior cervical ganglion

scientific article published on 01 May 1993

Immunohistochemical heterogeneity of nerve cells in the human adrenal gland with special reference to substance P

scientific article published on 01 April 1996

Immunohistochemistry of small intensely fluorescent (SIF) cells and of SIF cell-associated nerve fibers in the rat superior cervical ganglion

scientific article published on 01 October 1994

Improved NlaIII digestion of PAGE-purified 102 bp ditags by addition of a single purification step in both the SAGE and microSAGE protocols

scientific article published on June 2000

In Zucker diabetic fatty rats, subclinical diabetic neuropathy increases in vivo lidocaine block duration but not in vitro neurotoxicity.

scientific article

In vitro, inhibition of mitogen-activated protein kinase pathways protects against bupivacaine- and ropivacaine-induced neurotoxicity

scientific article published in May 2008

In vitro, lidocaine-induced axonal injury is prevented by peripheral inhibition of the p38 mitogen-activated protein kinase, but not by inhibiting caspase activity

scientific article

Increased expression of nitric oxide synthase in a subpopulation of rat sympathetic neurons after axotomy - correlation with vasoactive intestinal peptide

scientific article published on 01 September 1996

Increased innervation of rat preganglionic sympathetic neurons by substance P containing nerve fibers in response to spinal cord injury

scientific article published on 01 July 2001

Inhibition of calpains fails to improve regeneration through a peripheral nerve conduit.

scientific article published on 13 March 2014

Inhibition of fibroblast growth factor receptor 1 endocytosis promotes axonal branching of adult sensory neurons

scientific article published on 07 May 2011

Introduction: Thematic Papers Issue on "Advances in Our Understanding of the Morphological Response to Injury in the Peripheral Nervous System"

scientific article published on 26 June 2019

Involvement of Peripheral Nerves in the Transgenic PLP-α-Syn Model of Multiple System Atrophy: Extending the Phenotype

scientific article published on 23 October 2015

Leupeptin enhances cell surface localization of fibroblast growth factor receptor 1 in adult sensory neurons by increased recycling.

scientific article published on 9 December 2011

Localization and axotomy-induced regulation of the peptide secretoneurin in the rat superior cervical ganglion

scientific article published on 01 September 1996

Localization and regulation of basic fibroblast growth factor (FGF-2) and FGF receptor-1 in rat superior cervical ganglion after axotomy

scientific article published on 01 March 1999

Localization, regulation and functions of neurotransmitters and neuromodulators in cervical sympathetic ganglia

scientific article published on September 1996

Membrane turnover and receptor trafficking in regenerating axons

scientific article published on 27 July 2015

Membrane-Associated, Not Cytoplasmic or Nuclear, FGFR1 Induces Neuronal Differentiation

scientific article published on 14 March 2019

Mitigation of direct neurotoxic effects of lidocaine and amitriptyline by inhibition of p38 mitogen-activated protein kinase in vitro and in vivo

scientific article published in June 2006

Neurochemistry, connectivity and plasticity of small intensely fluorescent (SIF) cells in the rat superior cervical ganglion

scientific article published on 01 August 1993

Neurotoxicity of lidocaine involves specific activation of the p38 mitogen-activated protein kinase, but not extracellular signal-regulated or c-jun N-terminal kinases, and is mediated by arachidonic acid metabolites

scientific article published on November 2006

New developments in the field of peripheral nerve regeneration

scientific article published on 08 April 2011

Nitric oxide synthase in cardiac nerve fibers and neurons of rat and guinea pig heart

scientific article

PACAP immunoreactivity in the rat superior cervical ganglion in comparison to VIP

scientific article published on 01 November 1996

Pea3 transcription factor promotes neurite outgrowth

scientific article

Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice

scientific article published on 25 April 2008

Phosphorylation-regulated cleavage of the reticulon protein Nogo-B by caspase-7 at a noncanonical recognition site

scientific article published in December 2007

Plasticity of neuropeptide Y in the rat superior cervical ganglion in response to nerve lesion

scientific article published on 01 May 1997

Plasticity of postganglionic sympathetic neurons in the rat superior cervical ganglion after axotomy

scientific article published on 01 October 1994

Poor functional recovery and muscle polyinnervation after facial nerve injury in fibroblast growth factor-2-/- mice can be improved by manual stimulation of denervated vibrissal muscles

scientific article published on 31 March 2011

Postnatal development of the locus coeruleus in trisomy 19 mice: morphological and morphometric study

scientific article published in June 1992

Promotion of Peripheral Nerve Regeneration by Stimulation of the Extracellular Signal-Regulated Kinase (ERK) Pathway

scientific article published on 22 April 2019

Promotion of neurite outgrowth by fibroblast growth factor receptor 1 overexpression and lysosomal inhibition of receptor degradation in pheochromocytoma cells and adult sensory neurons

scientific article published on 4 March 2008

Regulation of clusterin expression following spinal cord injury

scientific article published on 01 November 2001

Regulation of galanin in rat sympathetic neurons in vitro ⬇️

scientific article published on 01 October 1997

Rho GTPases as regulators of morphological neuroplasticity

scientific article published on 12 March 2011

Rho-independent stimulation of axon outgrowth and activation of the ERK and Akt signaling pathways by C3 transferase in sensory neurons

scientific article

Secretion and molecular forms of NESP55, a novel genomically imprinted neuroendocrine-specific protein from AtT-20 cells.

scientific article

Secretoneurin in the peripheral ocular innervation.

scientific article published in February 2005

Secretoneurin-immunoreactivity in nerve terminals apposing identified preganglionic sympathetic neurons in the rat: colocalization with substance P and enkephalin

scientific article published in July 1995

Selective up-regulation of the vasodilator peptide apelin after dorsal root but not after spinal nerve injury

scientific article published on 3 August 2010

Signaling by neuronal tyrosine kinase receptors: relevance for development and regeneration.

scientific article published on December 2009

Sorting of the FGF receptor 1 in a human glioma cell line

scientific article published on 18 August 2012

Sprouty2 and -4 hypomorphism promotes neuronal survival and astrocytosis in a mouse model of kainic acid induced neuronal damage

scientific article

Sprouty2 and -4 regulate axon outgrowth by hippocampal neurons.

scientific article published on 14 January 2011

Sprouty2 down-regulation promotes axon growth by adult sensory neurons

scientific article published on 14 August 2009

Sprouty2-a Novel Therapeutic Target in the Nervous System?

scientific article

Target-dependent plasticity of galanin and vasoactive intestinal peptide in the rat superior cervical ganglion after nerve lesion and re-innervation

scientific article published in May 1996

The N-end rule ubiquitin-conjugating enzyme, HR6B, is up-regulated by nerve growth factor and required for neurite outgrowth

scientific article published on 01 August 2005

The axotomy-induced neuropeptides galanin and pituitary adenylate cyclase-activating peptide promote axonal sprouting of primary afferent and cranial motor neurones

scientific article published on 01 September 2006

The neurotoxic effects of amitriptyline are mediated by apoptosis and are effectively blocked by inhibition of caspase activity

scientific article published in June 2006

The pros and cons of growth factors and cytokines in peripheral axon regeneration.

scientific article published on January 2013

The transcriptional corepressor TPA-inducible sequence 7 regulates adult axon growth through cellular retinoic acid binding protein II expression

scientific journal article

Tissue distribution of the "N-end rule" ubiquitin-conjugating enzyme, HR6, in the rat.

scientific article published on 3 May 2005

Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia.

scientific article published on 25 October 2012

Tumor necrosis factor-alpha-induced cell death in U373 cells overexpressing alpha-synuclein

scientific article published in August 2003

Ubiquitin-dependent proteolysis in neurons.

scientific article

Ultrastructure of α-synuclein-positive aggregations in U373 astrocytoma and rat primary glial cells

scientific article published on 01 April 2002

VIP - a ’Very Important Peptide' in the sympathetic nervous system? ⬇️

scientific article published on October 1, 1997

Vasoactive intestinal peptide but not galanin promotes survival of neonatal rat sympathetic neurons and neurite outgrowth of PC12 cells

scientific article published on 01 August 1995

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