List of works - Christophe Guilluy

AMPK alpha 1-induced RhoA phosphorylation mediates vasoprotective effect of estradiol

scientific article published in November 2011

Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus

scientific article published in December 2011

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads.

scientific article published on 8 March 2017

Analyzing Mechanotransduction Through the LINC Complex in Isolated Nuclei

scientific article published on 01 January 2018

Colorectal Cancer Cells Adhere to and Migrate Along the Neurons of the Enteric Nervous System

scientific article published on 14 October 2017

Focal adhesions, stress fibers and mechanical tension

scientific article

From mechanical force to RhoA activation

scientific article

Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells.

scientific article

Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation.

scientific article

Increased Rho-kinase expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function.

scientific article

Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension

scientific journal article

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.

scientific article

Latent KSHV infection increases the vascular permeability of human endothelial cells ⬇️

scientific article published on August 31, 2011

Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway

scientific article

Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells

scientific article

Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells

scientific article

Mechanotransduction via the nuclear envelope: a distant reflection of the cell surface.

scientific article published on 26 October 2016

Nuclear envelope deformation controls cell cycle progression in response to mechanical force

scientific article published on 01 August 2019

Nuclear mechanotransduction: forcing the nucleus to respond

scientific article

RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome

scientific article published on 01 October 2019

Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

scientific article

Rho protein crosstalk: another social network?

scientific article published on 15 September 2011

RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling

scientific article

Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms

scientific article published on 20 November 2019

Ste20-related kinase SLK phosphorylates Ser188 of RhoA to induce vasodilation in response to angiotensin II Type 2 receptor activation

scientific journal article

Syndecan-4 forces integrins to cooperate

scientific article published on 01 June 2020

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

scientific article

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure.

scientific article published on 24 January 2010

The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.

scientific article published on 28 February 2014

The Vinculin C-terminal Hairpin Mediates F-actin Bundle Formation, Focal Adhesion, and Cell Mechanical Properties ⬇️

scientific article published on November 3, 2011

The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals

scientific article

Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells.

scientific article published on 02 December 2006

Under Pressure: Mechanical Stress Management in the Nucleus

scientific article

Using magnets and magnetic beads to dissect signaling pathways activated by mechanical tension applied to cells

scientific article published on 28 September 2015

Vinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesions

scientific article

List of works by Christophe Guilluy

AMPK alpha 1-induced RhoA phosphorylation mediates vasoprotective effect of estradiol

Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads.

Analyzing Mechanotransduction Through the LINC Complex in Isolated Nuclei

Colorectal Cancer Cells Adhere to and Migrate Along the Neurons of the Enteric Nervous System

Focal adhesions, stress fibers and mechanical tension

From mechanical force to RhoA activation

Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells.

Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation.

Increased Rho-kinase expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function.

Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.

Latent KSHV infection increases the vascular permeability of human endothelial cells ⬇️

Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway

Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells

Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells

Mechanotransduction via the nuclear envelope: a distant reflection of the cell surface.

Nuclear envelope deformation controls cell cycle progression in response to mechanical force

Nuclear mechanotransduction: forcing the nucleus to respond

RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome

Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

Rho protein crosstalk: another social network?

RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling

Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms

Ste20-related kinase SLK phosphorylates Ser188 of RhoA to induce vasodilation in response to angiotensin II Type 2 receptor activation

Syndecan-4 forces integrins to cooperate

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure.

The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.

The Vinculin C-terminal Hairpin Mediates F-actin Bundle Formation, Focal Adhesion, and Cell Mechanical Properties ⬇️

The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals

Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells.

Under Pressure: Mechanical Stress Management in the Nucleus

Using magnets and magnetic beads to dissect signaling pathways activated by mechanical tension applied to cells

Vinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesions