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List of works by Markus Hoth

A GTP-dependent step in the activation mechanism of capacitative calcium influx

scientific article published on 01 October 1993

A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity.

scientific article

A new rapid and simple method to determine the kinetics of electrode reactions of biologically relevant compounds from the half-peak width of the square-wave voltammograms.

scientific article

A simple, economic, time-resolved killing assay

scientific article published on 13 April 2014

AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum

scientific article published in Nature Communications

Apparent cytosolic calcium gradients in T-lymphocytes due to fura-2 accumulation in mitochondria

scientific article

CRAC channels, calcium, and cancer in light of the driver and passenger concept

scientific article published on 16 December 2015

Ca2+ and Mn2+ influx through receptor-mediated activation of nonspecific cation channels in mast cells

scientific article

Ca2+ signaling in identified T-lymphocytes from human intestinal mucosa. Relation to hyporeactivity, proliferation, and inflammatory bowel disease

scientific article published on 29 October 2003

CaMKII does not control mitochondrial Ca2+ uptake in cardiac myocytes

scientific article published on 27 March 2019

Calcium and barium permeation through calcium release-activated calcium (CRAC) channels

scientific article published on 01 July 1995

Calcium binding and transport by coenzyme Q

scientific article published on 24 May 2011

Calcium dependence of T cell proliferation following focal stimulation

scientific article published on 01 October 2007

Calcium influx and its control by calcium release

scientific article published on June 1993

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation.

scientific article

Calcium release-activated calcium current in rat mast cells

scientific article published on 01 June 1993

Calcium signal dynamics in T lymphocytes: Comparing in vivo and in vitro measurements

scientific article published on 11 January 2019

Calcium, cancer and killing: The role of calcium in killing cancer cells by cytotoxic T lymphocytes and natural killer cells ⬇️

scientific article published on 03 December 2012

Calcium-dependent activation of T-lymphocytes.

scientific article

Can we see PIP(3) and hydrogen peroxide with a single probe?

scientific article published on 10 April 2012

Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels.

scientific article

Cytoskeleton rotation relocates mitochondria to the immunological synapse and increases calcium signals.

scientific article published on 7 July 2016

DNA methylation array analyses identified breast cancer-associatedHYAL2methylation in peripheral blood

DNA methylation array analysis identifies breast cancer associated RPTOR, MGRN1 and RAPSN hypomethylation in peripheral blood DNA.

scientific article published on 26 August 2016

Deep characterization of blood cell miRNomes by NGS

scientific article published on 13 February 2016

Depletion of intracellular calcium stores activates a calcium current in mast cells

scientific article published in January 1992

Depletion of intracellular calcium stores activates an outward potassium current in mast and RBL-1 cells that is correlated with CRAC channel activation

scientific article published on 01 July 1996

Deterministic actin waves as generators of cell polarization cues

scientific article published on 27 December 2019

Different Munc13 isoforms function as priming factors in lytic granule release from murine cytotoxic T lymphocytes

scientific article published on 9 May 2013

Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling

scientific article published on 30 March 2010

Disruption of the cortical actin cytoskeleton does not affect store operated Ca2+ channels in human T-cells

scientific article published on 3 July 2007

Docking of Lytic Granules at the Immunological Synapse in Human CTL Requires Vti1b-Dependent Pairing with CD3 Endosomes

scientific article published on 11 May 2011

Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry.

scientific article published on 12 October 2009

Electrochemical Quantification of Extracellular Local H2O2 Kinetics Originating from Single Cells.

scientific article

Enhancement of calcium signalling dynamics and stability by delayed modulation of the plasma-membrane calcium-ATPase in human T cells

scientific article

Excitable T cells: Ca(v)1.4 channel contributions and controversies

scientific article published on 01 September 2011

How ORAI and TRP channels interfere with each other: interaction models and examples from the immune system and the skin.

scientific article

Human T cells monitored by impedance spectrometry using field-effect transistor arrays: a novel tool for single-cell adhesion and migration studies

article

Human profilin 1 is a negative regulator of CTL mediated cell-killing and migration.

scientific article

Hydroxylated derivatives of dimethoxy-1,4-benzoquinone as redox switchable earth-alkaline metal ligands and radical scavengers.

scientific article

IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer

scientific article published on 17 July 2019

Immune synapses: mitochondrial morphology matters

scientific article published on April 2011

Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry

scientific article published on 7 March 2014

Ion channels and calcium signaling in mast cells

scientific article published on December 1993

Ion channels in health and disease. 83rd Boehringer Ingelheim Fonds International Titisee Conference

scientific article published on July 2001

Light-sheet Microscopy for Three-dimensional Visualization of Human Immune Cells

scientific article published on 13 June 2018

Measuring endogenous ICRAC and ORAI currents with the patch-clamp technique

scientific article published on 02 June 2014

Mitochondria positioning controls local calcium influx in T cells

scientific article published on 30 November 2009

Mitochondrial dynamics and their impact on T cell function.

scientific article published on 14 March 2012

Molecular regulation of CRAC channels and their role in lymphocyte function ⬇️

scientific article published on October 5, 2012

Morphological changes of T cells following formation of the immunological synapse modulate intracellular calcium signals

scientific article published on 13 September 2008

Multiple mechanisms of manganese-induced quenching of fura-2 fluorescence in rat mast cells

scientific article published on 01 May 1993

NFATc1 controls the cytotoxicity of CD8+ T cells

scientific article published on 11 September 2017

Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification, and modulation of apoptosis, necrosis, and mixed forms

scientific article published on 06 September 2018

New insights into the chemistry of Coenzyme Q-0: A voltammetric and spectroscopic study

scientific article published on 29 May 2016

Non-specific effects of calcium entry antagonists in mast cells

scientific article published on 01 October 1994

Nonsteroidal anti-inflammatory drugs inhibit vascular smooth muscle cell proliferation by enabling the Ca2+-dependent inactivation of calcium release-activated calcium/orai channels normally prevented by mitochondria.

scientific article published on 14 March 2011

ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance.

scientific article published on 12 June 2011

ORAI1 Ca(2+) channels control endothelin-1-induced mitogenesis and melanogenesis in primary human melanocytes

scientific article published on 09 February 2012

Optimality of Spatially Inhomogeneous Search Strategies. ⬇️

scientific article

Optoregulated force application to cellular receptors using molecular motors

scientific article published on 11 June 2021

Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells

scientific article published on June 2013

P2X(7) receptor stimulation upregulates Egr-1 biosynthesis involving a cytosolic Ca(2+) rise, transactivation of the EGF receptor and phosphorylation of ERK and Elk-1.

scientific article published on October 2007

Patch-clamp measurement of ICRAC and ORAI channel activity

scientific article published on 02 June 2014

Pharmacology of ORAI channels as a tool to understand their physiological functions.

scientific article published on May 2010

Plant sterol ester diet supplementation increases serum plant sterols and markers of cholesterol synthesis, but has no effect on total cholesterol levels

scientific article published on 26 July 2016

Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2.

scientific article

Probing the redox activity of T-lymphocytes deposited at electrode surfaces with voltammetric methods.

scientific article published on January 2008

Profilin 1 potentiates apoptosis induced by staurosporine in cancer cells

scientific article published on March 2013

Protein Signatures of NK Cell-Mediated Melanoma Killing Predict Response to Immunotherapies

scientific article published on 13 September 2021

Protein-film voltammetry: a theoretical study of the temperature effect using square-wave voltammetry.

scientific article published on 8 July 2008

Quantity, quality, and functionality of peripheral blood cells derived from residual blood of different apheresis kits

scientific article published on 06 May 2018

Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens

scientific article

Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide

scientific article

Redox properties of the calcium chelator Fura-2 in mimetic biomembranes

scientific article published on 14 November 2007

Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure.

scientific article

SNARE protein expression and localization in human cytotoxic T lymphocytes

scientific article published on 05 January 2012

STIM-Orai Channels and Reactive Oxygen Species in the Tumor Microenvironment

scientific article published on 30 March 2019

Skeletal muscle L-type Ca(2+) current modulation in gamma1-deficient and wildtype murine myotubes by the gamma1 subunit and cAMP.

scientific article published in March 2002

Sustained activity of calcium release-activated calcium channels requires translocation of mitochondria to the plasma membrane

scientific article published on 20 October 2006

Swapping of functional domains in voltage-gated K+ channels

scientific article published on 01 August 1991

Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes

scientific article published on 16 April 2016

Syntaxin11 serves as a t-SNARE for the fusion of lytic granules in human cytotoxic T lymphocytes

scientific article published on 16 December 2013

Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes

scientific article

T cell activation requires mitochondrial translocation to the immunological synapse

scholarly article

TRP channels in lymphocytes.

scientific article published on January 2007

TRP expression pattern and the functional importance of TRPC3 in primary human T-cells.

scientific article

TRP4 (CCE1) protein is part of native calcium release-activated Ca2+-like channels in adrenal cells

scientific article published in August 2000

TRPC3 mediates T-cell receptor-dependent calcium entry in human T-lymphocytes

scientific article published on 6 May 2003

TRPV6 potentiates calcium-dependent cell proliferation

scientific article published on 13 December 2005

Thapsigargin induces expression of activating transcription factor 3 in human keratinocytes involving Ca2+ ions and c-Jun N-terminal protein kinase

scientific article published on 16 August 2010

The PDZ-interacting domain of TRPC4 controls its localization and surface expression in HEK293 cells.

scientific article published on September 2002

The extracellular adherence protein (Eap) of Staphylococcus aureus acts as a proliferation and migration repressing factor that alters the cell morphology of keratinocytes.

scientific article published on 18 January 2017

The immunological synapse controls local and global calcium signals in T lymphocytes.

scientific article published on September 2009

The minimal requirements to use calcium imaging to analyze ICRAC

scientific article published on 02 June 2014

Two-photon analysis of calcium signals in T lymphocytes of intact lamina propria from human intestine.

scientific article published in December 2004

VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity

scientific article published on 29 June 2015

miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling

scientific article published on 18 January 2019

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