Search filters

List of works by Andras Perl

Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation

scientific article

Activation of the Mechanistic Target of Rapamycin in SLE: Explosion of Evidence in the Last Five Years

scientific article published on December 2016

Adhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF)

scientific journal article

Advances in the o-phthalaldehyde derivatizations. Comeback to the o-phthalaldehyde-ethanethiol reagent.

scientific article published on 13 June 2007

Analysis of amino acids and biogenic amines in biological tissues as their o-phthalaldehyde/ethanethiol/fluorenylmethyl chloroformate derivatives by high-performance liquid chromatography. A deproteinization study

scientific article published on 04 December 2006

Antibody reactivity to the HRES-1 endogenous retroviral element identifies a subset of patients with systemic lupus erythematosus and overlap syndromes. Correlation with antinuclear antibodies and HLA class II alleles

scientific article published on 01 November 1995

Antiphospholipid antibody syndrome associated with primary angiitis of the central nervous system: report of two biopsy proven cases

scientific article published on March 2006

Apoptosis and mitochondrial dysfunction in lymphocytes of patients with systemic lupus erythematosus

scientific article

Association of common mitochondrial DNA variants with multiple sclerosis and systemic lupus erythematosus

scientific article published on 16 August 2008

Attention deficit and hyperactivity disorder scores are elevated and respond to N-acetylcysteine treatment in patients with systemic lupus erythematosus

scientific article

CCL genes in multiple sclerosis and systemic lupus erythematosus

scientific article

CD8+ T cell-mediated HLA-A*0201-restricted cytotoxicity to transaldolase peptide 168-176 in patients with multiple sclerosis

scientific article

Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus.

scientific article

Characterization of the effector cells in Con A-induced cytotoxicity against HEp 2 tumour targets

scientific article published on 01 January 1983

Cleavage of transaldolase by granzyme B causes the loss of enzymatic activity with retention of antigenicity for multiple sclerosis patients

scientific article

Clonal B cell expansions in patients with essential mixed cryoglobulinaemia

scientific article published on 01 April 1989

Cloning and expression of the human gene for transaldolase. A novel highly repetitive element constitutes an integral part of the coding sequence.

scientific article

Comparative analysis of antibody and cell-mediated autoimmunity to transaldolase and myelin basic protein in patients with multiple sclerosis

scientific article published on March 1997

Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin

scientific article

Contrasting effects of RNA and protein synthesis blocking on natural and lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells

scientific article published on October 1985

Deletion of Ser-171 causes inactivation, proteasome-mediated degradation and complete deficiency of human transaldolase

scientific article published on September 2004

Depressed effector activity of OKT4+ and OKT8+ T cell subsets in lectin-dependent cell-mediated cytotoxicity to HEP-2 cells in patients with systemic lupus erythematosus

scientific article published on 01 October 1984

Depressed lectin-dependent and enhanced antibody-dependent cell-mediated cytotoxicity in patients with stage I cancer of the larynx

scientific article published on 01 January 1986

Depressed lectin-dependent cell-mediated cytotoxicity against HEp-2 cells in patients with metastasizing solid tumour

scientific article published on 01 January 1985

Depressed lectin-dependent cell-mediated cytotoxicity against adherent HEP-2 cells in patients with carcinoma of the uterine cervix

scientific article published on 01 January 1983

Depressed natural and lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells in patients with systemic lupus erythematosus

scientific article published on 01 January 1982

Detection and cloning of new HTLV-related endogenous sequences in man

scientific article

Detection and mapping of polymorphic KpnI alleles in the human T-cell receptor constant beta-2 locus

scientific article published on 01 May 1989

Detection of lupus anticoagulant and successful anticoagulation in familial Sneddon syndrome

scientific article published on 01 April 2010

Differential regulation of hydrogen peroxide and Fas-dependent apoptosis pathways by dehydroascorbate, the oxidized form of vitamin C.

scientific article

Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus

scientific article published on December 2011

Effect of (+)cyanidanol-3 on cellular immune reactions and on superoxide dismutase activity in vitro

scientific article published on January 1987

Effect of Fc receptor blocking on human natural and lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells

scientific article published on 01 June 1983

Effect of histamine-receptor blocking on human natural and lectin-dependent cell-mediated cytotoxicity against adherent HEP-2 cells.

scientific article

Effector activity of OKT4+ and OKT8+ T-cell subsets in lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells

scientific article published on 01 March 1984

Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signaling

scientific article

Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome.

scientific article

Endogenous retroviral pathogenesis in lupus

scientific article published on September 2010

Endothelial nitric oxide synthase reduces crescentic and necrotic glomerular lesions, reactive oxygen production, and MCP1 production in murine lupus nephritis

scientific article

Evaluation of autoimmunity to transaldolase in multiple sclerosis

scientific article

Fatal toxic myopathy attributed to propofol, methylprednisolone, and cyclosporine after prior exposure to colchicine and simvastatin

scientific article

Genetic and metabolic control of the mitochondrial transmembrane potential and reactive oxygen intermediate production in HIV disease.

scientific article

Glutathione Levels and Sensitivity to Apoptosis Are Regulated by Changes in Transaldolase Expression

scientific article published in Journal of Biological Chemistry

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HRES-1/Rab4 promotes the formation of LC3(+) autophagosomes and the accumulation of mitochondria during autophagy

scientific article published on 3 January 2014

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.

scientific article

Haplotypes of the HRES-1 endogenous retrovirus are associated with development and disease manifestations of systemic lupus erythematosus

scientific article published on 01 February 2008

Human T-cell leukemia virus type I or a related retrovirus in patients with mycosis fungoides/Sézary syndrome and Kaposi's sarcoma ⬇️

scientific article published on August 15, 1992

Human T-cell lymphotropic virus (HTLV)-related endogenous sequence, HRES-1, encodes a 28-kDa protein: a possible autoantigen for HTLV-I gag-reactive autoantibodies ⬇️

scientific article published on March 1, 1992

Human lectin-dependent T cell-mediated cytotoxicity against Hep-2 cells

scientific article published on 01 January 1983

Human transaldolase and cross-reactive viral epitopes identified by autoantibodies of multiple sclerosis patients.

scientific article

Human transaldolase-associated repetitive elements are transcribed by RNA polymerase III.

scientific article published in March 2000

Hypoglycaemia after initiation of treatment with etanercept in a patient with type 2 diabetes mellitus

scientific article published on December 2007

Identification of mitochondrial genome concatemers in AIDS-associated lymphomas and lymphoid cell lines

scientific article published on 11 April 2009

Immunofluorescence microscopy is superior to fluorescent beads for detection of antinuclear antibody reactivity in systemic lupus erythematosus patients

scientific article published on 21 May 2007

Increased mitochondrial electron transport chain activity at complex I is regulated by N-acetylcysteine in lymphocytes of patients with systemic lupus erythematosus

scientific article

Increased prevalence of transfusion-transmitted virus and cross-reactivity with immunodominant epitopes of the HRES-1/p28 endogenous retroviral autoantigen in patients with systemic lupus erythematosus

scientific article

Independence of depressed lectin-dependent cell-mediated cytotoxicity from interleukin 2 production in patients with systemic lupus erythematosus

scientific article published on 01 August 1986

Indomethacin abrogates the suppression by cyclosporin A of lectin-dependent cell-mediated cytotoxicity to HEp-2 cells

scientific article published on 01 February 1986

Induction of systemic lupus erythematosus with tumor necrosis factor blockers

scientific article published on 01 January 2010

Infection in systemic lupus erythematosus: friend or foe?

scientific article

Inhibition of the catalytic activity of human transaldolase by antibodies and site-directed mutagenesis

scientific article published on 01 January 1996

Interplay of infections, autoimmunity, and immunosuppression in systemic lupus erythematosus

scientific article published on 28 January 2014

Ketoconazole in vitro inhibits mitogen-induced blastogenesis, antibody-dependent cellular cytotoxicity, natural killer activity and random migration of human leukocytes

scientific article published on 01 June 1984

Lectin-dependent cell-mediated cytotoxicity and blastogenesis by large granular-enriched and depleted lymphocytes

scientific article published in January 1986

Liver injury correlates with biomarkers of autoimmunity and disease activity and represents an organ system involvement in patients with systemic lupus erythematosus

scientific article

Lymphoedema: a paradoxical effect of tumour necrosis factor inhibitors - case report and review of literature

scientific article published on 05 March 2009

Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus

scientific article

Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus

scientific article

Metabolic control of the epigenome in systemic Lupus erythematosus

scientific article

Metabolic regulation of organelle homeostasis in lupus T cells

scientific article

Metabolic switches of T-cell activation and apoptosis

scientific article

Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus-Prone Mice

scientific article published on 22 June 2016

Mitochondrial dysfunction in T cells of patients with systemic lupus erythematosus

scientific article published on May 2004

Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus

scientific article (publication date: 2002)

Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity

scientific article

Mitochondrial involvement and erythronic acid as a novel biomarker in transaldolase deficiency

scientific article published on 18 June 2010

Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE.

scientific article published on May 2008

Molecular ordering in HIV-induced apoptosis. Oxidative stress, activation of caspases, and cell survival are regulated by transaldolase

scientific article

Murine lupus susceptibility locus Sle1c2 mediates CD4+ T cell activation and maps to estrogen-related receptor γ.

scientific article

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial

scientific article

Nitric oxide, mitochondrial hyperpolarization, and T cell activation

scientific article

Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells

scientific article

Oligodendrocyte-specific expression and autoantigenicity of transaldolase in multiple sclerosis

scientific article

Overview of signal processing by the immune system in systemic lupus erythematosus.

scientific article published on 21 August 2008

Oxidative Stress and ADHD: A Meta-Analysis

scientific article

Oxidative stress and Treg depletion in lupus patients with anti-phospholipid syndrome

scientific article published on 8 April 2015

Oxidative stress and endosome recycling are complementary mechanisms reorganizing the T-cell receptor signaling complex in SLE ⬇️

scientific article published on December 30, 2011

Oxidative stress in the pathology and treatment of systemic lupus erythematosus

scientific article

Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase

scientific article

Pathogenic mechanisms in systemic lupus erythematosus.

scientific article

Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus

scientific article

Pharmacotherapy of systemic lupus erythematosus.

scientific article published on June 2009

Polymerase chain reaction in clinical diagnosis

scientific article published in April 1990

Polymorphic genotypes of the HRES-1 human endogenous retrovirus locus correlate with systemic lupus erythematosus and autoreactivity

scientific article published on 01 September 1999

Possible pathogenic nature of the recently discovered TT virus: does it play a role in autoimmune rheumatic diseases?

scientific article published on 19 April 2006

Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine

scientific article published on 11 May 2009

Psychiatric Symptoms in Systemic Lupus Erythematosus

scholarly article by Zsuzsa Szombathyne Meszaros et al published 1 May 2012 in The Journal of Clinical Psychiatry

Psychiatric symptoms in systemic lupus erythematosus: a systematic review

scientific article published on May 2012

Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus

scientific article

Rearrangement of the T-cell receptor alpha, beta and gamma chain genes in chronic lymphocytic leukemia

scientific article published on 01 January 1990

Regulation of CD4 expression via recycling by HRES-1/RAB4 controls susceptibility to HIV infection

scientific article published on 24 August 2006

Relationship between posttranslational modification of transaldolase and catalase deficiency in UV-sensitive repair-deficient xeroderma pigmentosum fibroblasts and SV40-transformed human cells

scientific article

Signaling abnormalities in systemic lupus erythematosus as potential drug targets

scientific article published on December 2006

Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.

scientific article published on 15 March 2018

Stimulation by thymopoietin oligopeptides of lectin-dependent cell-mediated cytotoxicity in patients with systemic lupus erythematosus

scientific article published on 01 November 1985

Stimulation of lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells by carrageenan

scientific article published on 01 November 1983

Stimulation of the pentose phosphate pathway and glutathione levels by dehydroascorbate, the oxidized form of vitamin C.

scientific article published on July 2000

Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment.

scientific article

T Cell Activation-Induced Mitochondrial Hyperpolarization Is Mediated by Ca2+- and Redox-Dependent Production of Nitric Oxide ⬇️

scientific article published on November 15, 2003

T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

scientific article

T- and B-cell abnormalities in systemic lupus erythematosus

scientific article

T-cell and B-cell signaling biomarkers and treatment targets in lupus

scientific article

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice

scientific article published on 16 April 2020

The combination of nuclear and mitochondrial mutations as a risk factor for idiosyncratic toxicity

scientific article published on 30 August 2006

The human T-cell leukemia virus-related endogenous sequence (HRES1) is located on chromosome 1 at q42.

scientific article published in December 1991

The human transaldolase gene (TALDO1) is located on chromosome 11 at p15.4-p15.5

scientific article

The pathogenesis of transaldolase deficiency

scientific article (publication date: June 2007)

The role of nitric oxide in abnormal T cell signal transduction in systemic lupus erythematosus

scientific article

The three-dimensional structure of human transaldolase

scientific article

Transaldolase deficiency influences the pentose phosphate pathway, mitochondrial homoeostasis and apoptosis signal processing

scientific article

Transaldolase haploinsufficiency in subjects with acetaminophen-induced liver failure

scientific article published on 26 November 2019

Transaldolase is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa

scientific article published on 26 September 2006

Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine

scientific article published on 10 February 2020

Tuberous sclerosis and fulminant lupus in a young woman.

scientific article

ZNF143 mediates basal and tissue-specific expression of human transaldolase

scientific article

[Effect of Litoralon therapy on the lymphocytotoxicity in patients with malignant tumors]

scientific article published on 01 September 1984

[Natural and lectin-dependent cell-mediated cytotoxicity in patients with SLE and metastasizing solid tumors]

scientific article published on 01 January 1984

mTOR activation triggers proinflammatory expansion of IL-4-producing and necrosis-prone double-negative T cells, precedes flares, and serves as target for treatment in patients with systemic lupus erythematosus

scientific article published on 18 September 2014

Paulina is supported by:

About Paulina

Help