List of works by Robert Zimmermann

A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase

scientific article

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6

scientific article

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

scientific article published on 21 August 2011

Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase

scientific article published in May 2012

Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

scientific article published in Science

Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine

scientific article published on 27 September 2008

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

scientific article published on 16 January 2014

Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers

scientific article

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

scientific journal article

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

scientific article published on 23 October 2008

Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training

scientific article published on 23 December 2008

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells

scientific article published on 27 February 2015

Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids

scientific article

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

scientific article

Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier

scientific article published on 23 January 2013

Chemical Genetic Approaches for the Investigation of Neutral Lipid Metabolism

scientific article published on 30 December 2015

Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363

scientific article

Class B scavenger receptors CD36 and SR-BI are receptors for hypochlorite-modified low density lipoprotein

scientific article published on 10 September 2003

Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle

scientific article published on 15 October 2013

Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p

scientific article

Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone-sensitive lipase-deficient white adipose tissue

scientific article published on 16 August 2003

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

scientific article

Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation

scientific article

Development of small-molecule inhibitors targeting adipose triglyceride lipase

scientific article published on 6 October 2013

Effect of the cannabinoid receptor-1 antagonist rimonabant on lipolysis in rats

scientific article published on 18 August 2010

Endogenously produced glycosaminoglycans affecting the release of lipoprotein lipase from macrophages and the interaction with lipoproteins

scientific article

Endogenously produced lipoprotein lipase enhances the binding and cell association of native, mildly oxidized and moderately oxidized low-density lipoprotein in mouse peritoneal macrophages

scientific article published on October 1999

Endothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymic activity

scientific article

Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue

scientific article published on January 2005

Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver

scientific article published on 31 August 2009

FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling

scientific article published in March 2012

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

scientific article

Fate of fat: the role of adipose triglyceride lipase in lipolysis

scientific article published on 29 October 2008

Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling

scientific article published on 7 May 2015

Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.

scientific article published on 14 February 2013

G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.

scientific article published on 8 September 2015

G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase

scientific article published on 13 August 2012

Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).

scientific article

Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis

scientific journal article

Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle

scientific article published on 23 January 2002

Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity

scientific article

Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase.

scientific article published on 11 January 2018

Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae

scientific article

Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase

scientific journal article

Implications of endogenous and exogenous lipoprotein lipase for the selective uptake of HDL3-associated cholesteryl esters by mouse peritoneal macrophages

scientific article published on 01 February 1997

Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice

scientific article

Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase

scientific article published on 9 June 2015

Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population

scientific article

LPL-mediated lipolysis of VLDL induces an upregulation of AU-rich mRNAs and an activation of HuR in endothelial cells

scientific article published on 21 February 2006

Letting lipids go: hormone-sensitive lipase

scientific article

Lipid droplets induced by secreted phospholipase A2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress

scientific article published on 8 December 2017

Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress

scientific article

Lipidomic data on lipid droplet triglyceride remodelling associated with protection of breast cancer cells from lipotoxic stress.

scientific article published on 12 March 2018

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores ⬇️

scientific article published on November 16, 2010

Lipolysis: pathway under construction

scientific article

Lipoprotein lipase mediates the uptake of glycated LDL in fibroblasts, endothelial cells, and macrophages

scientific article

Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism

scientific article

Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia

scientific article published on 17 May 2016

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover

scientific article published on 27 June 2016

Measurement of lipolysis

scientific article published on January 2014

Metabolism of Lp(a): assembly and excretion

scientific article published on 01 November 1997

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism

scientific article published on 31 March 2016

Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling

scientific article published on 14 February 2017

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice

scientific article

Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity

scientific article published on 30 July 2015

Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

scientific article

Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice

scientific article

Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.

scientific article published on 28 April 2009

Nonoxidative ethanol metabolism in humans-from biomarkers to bioactive lipids

scientific article published on 06 October 2016

Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast

scientific article

PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans

scientific article

Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice

scientific article published on 22 March 2017

Remodeling of lipid droplets during lipolysis and growth in adipocytes

scientific article

Retinyl ester hydrolases and their roles in vitamin A homeostasis

scientific article published on 08 May 2011

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

article

Role of macrophage-derived lipoprotein lipase in lipoprotein metabolism and atherosclerosis

scientific article published on 01 September 2000

Secretory phospholipase A2 modified HDL rapidly and potently suppresses platelet activation

scientific article published on 14 August 2017

Structure-activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL).

scientific article published on 5 March 2015

Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases

scientific article published on 12 October 2012

Symptomatic lipid storage in carriers for the PNPLA2 gene

scientific article published on 12 December 2012

Symptomatic lipid storage in carriers for the PNPLA2 gene.

scientific article

The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes

scientific article

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

scientific article published in Journal of Biological Chemistry

The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase

scientific article

The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition.

scientific article

The impact of genetic stress by ATGL deficiency on the lipidome of lipid droplets from murine hepatocytes

scientific article published on 05 June 2013

The interplay of protein kinase A and perilipin 5 regulates cardiac lipolysis

scientific article

The lipid droplet enzyme Tgl1p hydrolyzes both steryl esters and triglycerides in the yeast, Saccharomyces cerevisiae

scientific article published in June 2005

The lipolytic proteome of mouse adipose tissue

scientific article published on 26 July 2005

The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively

scientific article

The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome

scientific journal article

The sparing use of fat: G0s2 controls lipolysis and fatty acid oxidation

scientific article published on 29 October 2014

The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes

scientific article

α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate

scientific article published on 21 October 2015

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