List of works by Achim Lass

A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics

scientific article

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

scientific article

A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase

scientific article

A sensitive chemiluminescence method to measure the lipoxygenase catalyzed oxygenation of complex substrates

scientific article

ABHD5 Stimulates PNPLA1-mediated Omega-O-Acylceramide Biosynthesis Essential for a Functional Skin Permeability Barrier

scientific article published on 25 October 2018

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6

scientific article

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

scientific article published on 21 August 2011

Abnormal composition and function of high-density lipoproteins in atopic dermatitis patients

scientific article published on 30 October 2018

Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase

scientific article published in May 2012

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

scientific article published on 16 January 2014

Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

scientific article

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

scientific journal article

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

scientific article published on 23 October 2008

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells

scientific article published on 27 February 2015

Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids

scientific article

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

scientific article

Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.

scientific article

Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice

scientific article published on 02 July 2019

Antioxidative and myocardial protective effects of L-arginine in oxygen radical-induced injury of isolated perfused rat hearts

scientific article published in March 2002

Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria

scientific article

Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier

scientific article published on 23 January 2013

Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363

scientific article

Comparative transcriptomics reveals candidate carotenoid color genes in an East African cichlid fish

scientific article published on 16 January 2020

Comparisons of coenzyme Q bound to mitochondrial membrane proteins among different mammalian species

scientific article published on 01 July 1999

DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signaling

scientific article

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

scientific article

Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation

scientific article

Development of small-molecule inhibitors targeting adipose triglyceride lipase

scientific article published on 6 October 2013

Effect of coenzyme Q(10) and alpha-tocopherol content of mitochondria on the production of superoxide anion radicals

scientific article published on 01 January 2000

Effects of coenzyme Q10 and alpha-tocopherol administration on their tissue levels in the mouse: elevation of mitochondrial alpha-tocopherol by coenzyme Q10.

scientific article

Electron transport-linked ubiquinone-dependent recycling of alpha-tocopherol inhibits autooxidation of mitochondrial membranes

scientific article published on 01 April 1998

Endothelialization of electrospun polycaprolactone (PCL) small caliber vascular grafts spun from different polymer blends.

scientific article

Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver

scientific article published on 31 August 2009

FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling

scientific article published in March 2012

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids

scientific article published on 27 February 2015

Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease.

scientific article published on April 2011

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

scientific article

Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes

scientific article published on 13 March 2014

Fate of fat: the role of adipose triglyceride lipase in lipolysis

scientific article published on 29 October 2008

Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling

scientific article published on 7 May 2015

Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis

scientific article

Functional and analytical evidence for scavenging of oxygen radicals by L-arginine

scientific article published in May 2002

Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.

scientific article published on 14 February 2013

G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase

scientific article published on 13 August 2012

Genetically modified mouse models to study hepatic neutral lipid mobilization

scientific article published on 05 June 2018

Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).

scientific article

Hepatic Retinyl Ester Hydrolases and the Mobilization of Retinyl Ester Stores

scientific article published on 27 December 2016

Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation

scientific article published on 25 April 2019

Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase

scientific journal article

Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: antioxidant actions in addition to hydroperoxide-reducing activity

scientific article published on 01 September 1996

Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress

scientific article

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores ⬇️

scientific article published on November 16, 2010

Lipolysis: pathway under construction

scientific article

Lipoxygenase treatment render low-density lipoprotein susceptible to Cu2+-catalysed oxidation

scientific article published on March 1996

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover

scientific article published on 27 June 2016

Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions

scientific article

Measurement of lipolysis

scientific article published on January 2014

Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans

scientific article published on 20 March 2019

Metabolic regulation of the lysosomal cofactor bis(monoacylglycero)phosphate in mice

scientific article published on 29 April 2020

Mitochondrial coenzyme Q content and aging

scientific article

Mitochondrial ubiquinone homologues, superoxide radical generation, and longevity in different mammalian species

scientific article

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice

scientific article

Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity

scientific article published on 30 July 2015

Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

scientific article

Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice

scientific article

Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.

scientific article published on 28 April 2009

PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.

scientific article published on 14 October 2016

Protein tyrosine nitration in cytokine-activated murine macrophages. Involvement of a peroxidase/nitrite pathway rather than peroxynitrite

scientific article

Protein tyrosine nitration in mouse peritoneal macrophages activated in vitro and in vivo: evidence against an essential role of peroxynitrite

scientific article

Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARγ.

scientific article published on 15 June 2010

Reduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes

scientific article published on 31 January 2014

Remodeling of lipid droplets during lipolysis and growth in adipocytes

scientific article

Retinyl ester hydrolases and their roles in vitamin A homeostasis

scientific article published on 08 May 2011

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

article

Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

scientific article

Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases

scientific article published on 12 October 2012

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

scientific article published in Journal of Biological Chemistry

The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase

scientific article

The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage

scientific article

The interplay of protein kinase A and perilipin 5 regulates cardiac lipolysis

scientific article

The lipolytic proteome of mouse adipose tissue

scientific article published on 26 July 2005

The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively

scientific article

α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate

scientific article published on 21 October 2015

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