List of works - Robin H Steinhorn

A randomized study of a monoclonal antibody (pagibaximab) to prevent staphylococcal sepsis

scientific article

Alterations in TGF-beta1 expression in lambs with increased pulmonary blood flow and pulmonary hypertension

scientific article published on 28 March 2003

Alterations in nitric oxide production in 8-week-old lambs with increased pulmonary blood flow

scientific article published in August 2002

Alveolar capillary dysplasia

scientific article

Antioxidant therapy for the treatment of pulmonary hypertension

scientific article published on 28 February 2013

Apocynin improves oxygenation and increases eNOS in persistent pulmonary hypertension of the newborn.

scientific article published on 23 December 2011

Beyond pulmonary hypertension: sildenafil for chronic lung disease of prematurity

scientific article

Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells.

scientific article

Chronic Pulmonary Insufficiency of Prematurity: Developing Optimal Endpoints for Drug Development

scientific article published in December 2017

Connecting the cells: vascular differentiation via homeobox genes and extracellular matrix in the distal lung

scientific article published in June 2004

Cyclic stretch induces inducible nitric oxide synthase and soluble guanylate cyclase in pulmonary artery smooth muscle cells

scientific article published on 21 February 2013

Developmental differences in hyperoxia-induced oxidative stress and cellular responses in the murine lung.

scientific article published on 14 March 2013

Developments in imaging: 'a huge difference in primary care'

scientific article published on 01 March 2012

Diagnosis and treatment of pulmonary hypertension in infancy

scientific article

Disrupted pulmonary artery cyclic guanosine monophosphate signaling in mice with hyperoxia-induced pulmonary hypertension.

scientific article published on February 2014

Emergence of smooth muscle cell endothelin B-mediated vasoconstriction in lambs with experimental congenital heart disease and increased pulmonary blood flow

scientific article published on 8 September 2003

Enhancing the Development and Retention of Physician-Scientists in Academic Pediatrics: Strategies for Success

article

Evaluation and management of the cyanotic neonate

scientific article published on September 2008

Every Week Matters ⬇️

scientific article published on April 22, 2011

Evidence-based guidelines for cardiovascular disease prevention in women: 2007 update

scientific article

Fetal origins of neonatal lung disease: understanding the pathogenesis of bronchopulmonary dysplasia

scientific article published on 30 September 2011

Hydrocortisone normalizes oxygenation and cGMP regulation in lambs with persistent pulmonary hypertension of the newborn

scientific article published on 23 December 2011

Hydrogen peroxide regulates extracellular superoxide dismutase activity and expression in neonatal pulmonary hypertension

scientific article published on 5 April 2011

Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cells

scientific article

Implications of the U.S. Food and Drug Administration warning against the use of sildenafil for the treatment of pediatric pulmonary hypertension.

scientific article published on 06 December 2012

In-house neonatology: what are we waiting for?

scientific article published on 01 September 2010

Increased p22(phox)/Nox4 expression is involved in remodeling through hydrogen peroxide signaling in experimental persistent pulmonary hypertension of the newborn.

scientific article published on 15 February 2013

Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidase

scientific article published on 27 February 2003

Inhaled nitric oxide and bronchopulmonary dysplasia

scientific article published on 01 July 2011

Inhaled nitric oxide for premature infants with severe respiratory failure

scientific article

Inhaled nitric oxide for preterm infants: a Marksman's approach

scientific article published on 23 June 2012

Inhaled prostacyclin for term infants with persistent pulmonary hypertension refractory to inhaled nitric oxide.

scientific article published in December 2002

Inodilators in nitric oxide resistant persistent pulmonary hypertension of the newborn

scientific article published on 01 January 2013

Intravenous sildenafil in the treatment of neonates with persistent pulmonary hypertension

scientific article published in December 2009

Late administration of surfactant replacement therapy increases surfactant protein-B content: a randomized pilot study

scientific article published on 4 October 2012

Medical and financial impact of a neonatal extracorporeal membrane oxygenation referral center in the nitric oxide era

scientific article published on 08 December 2008

Mitochondrial oxidant stress increases PDE5 activity in persistent pulmonary hypertension of the newborn.

scientific article

Neonatal extracorporeal life support: impact of new therapies on survival

scientific article published in May 2006

Neonatal pulmonary hypertension

scientific article published on March 2010

Nitric oxide and the developing airway

scientific article published on 01 December 2002

Nitric oxide decreases endothelin-1 secretion through the activation of soluble guanylate cyclase

scientific article published on 24 December 2003

Ovine bronchial-derived relaxing factor: changes with development and hyperoxic ventilation.

scientific article

Oxygen concentration and pulmonary hemodynamics in newborn lambs with pulmonary hypertension.

scientific article

Paracrine role of soluble guanylate cyclase and type III nitric oxide synthase in ovine fetal pulmonary circulation: a double labeling immunohistochemical study

scientific article

Pharmacotherapy for pulmonary hypertension

scientific article

Phosphodiesterases: Emerging Therapeutic Targets for Neonatal Pulmonary Hypertension ⬇️

scientific article published on January 1, 2011

Pre-term neonate with intestinal failure, feeding issues

scientific article published on 01 August 2011

Pulmonary Vasodilator Therapy in the NICU: Inhaled Nitric Oxide, Sildenafil, and Other Pulmonary Vasodilating Agents ⬇️

scientific article published on March 1, 2012

Pulmonary arterial contractility in neonatal lambs increases with 100% oxygen resuscitation

scientific article

Pulmonary hemodynamics in neonatal lambs resuscitated with 21%, 50%, and 100% oxygen.

scientific article

Pulmonary hypertension in bronchopulmonary dysplasia

scientific article published on April 2013

Regulation of phosphodiesterase 3 in the pulmonary arteries during the perinatal period in sheep

scientific article published on December 2009

Risk Assessment and Monitoring of Chronic Pulmonary Hypertension in Premature Infants

scientific article published on 14 November 2019

Role of BCL2-associated athanogene 1 in differential sensitivity of human endothelial cells to glucocorticoids.

scientific article published on 14 March 2013

Selective type 5 phosphodiesterase inhibition alters pulmonary hemodynamics and lung liquid production in near-term fetal lambs.

scientific article published on 25 August 2005

Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension

scientific article published on 12 September 2008

The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension.

scientific article published on 5 April 2018

The role of nitric oxide synthase-derived reactive oxygen species in the altered relaxation of pulmonary arteries from lambs with increased pulmonary blood flow.

scientific article

Therapeutic approaches using nitric oxide in infants and children.

scientific article

Type I nitric oxide synthase is decreased in the fetal pulmonary circulation of hypertensive lambs

scientific article published in June 2002

eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally.

scientific article

List of works by Robin H Steinhorn

A randomized study of a monoclonal antibody (pagibaximab) to prevent staphylococcal sepsis

Alterations in TGF-beta1 expression in lambs with increased pulmonary blood flow and pulmonary hypertension

Alterations in nitric oxide production in 8-week-old lambs with increased pulmonary blood flow

Alveolar capillary dysplasia

Antioxidant therapy for the treatment of pulmonary hypertension

Apocynin improves oxygenation and increases eNOS in persistent pulmonary hypertension of the newborn.

Beyond pulmonary hypertension: sildenafil for chronic lung disease of prematurity

Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells.

Chronic Pulmonary Insufficiency of Prematurity: Developing Optimal Endpoints for Drug Development

Connecting the cells: vascular differentiation via homeobox genes and extracellular matrix in the distal lung

Cyclic stretch induces inducible nitric oxide synthase and soluble guanylate cyclase in pulmonary artery smooth muscle cells

Developmental differences in hyperoxia-induced oxidative stress and cellular responses in the murine lung.

Developments in imaging: 'a huge difference in primary care'

Diagnosis and treatment of pulmonary hypertension in infancy

Disrupted pulmonary artery cyclic guanosine monophosphate signaling in mice with hyperoxia-induced pulmonary hypertension.

Emergence of smooth muscle cell endothelin B-mediated vasoconstriction in lambs with experimental congenital heart disease and increased pulmonary blood flow

Enhancing the Development and Retention of Physician-Scientists in Academic Pediatrics: Strategies for Success

Evaluation and management of the cyanotic neonate

Every Week Matters ⬇️

Evidence-based guidelines for cardiovascular disease prevention in women: 2007 update

Fetal origins of neonatal lung disease: understanding the pathogenesis of bronchopulmonary dysplasia

Hydrocortisone normalizes oxygenation and cGMP regulation in lambs with persistent pulmonary hypertension of the newborn

Hydrogen peroxide regulates extracellular superoxide dismutase activity and expression in neonatal pulmonary hypertension

Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cells

Implications of the U.S. Food and Drug Administration warning against the use of sildenafil for the treatment of pediatric pulmonary hypertension.

In-house neonatology: what are we waiting for?

Increased p22(phox)/Nox4 expression is involved in remodeling through hydrogen peroxide signaling in experimental persistent pulmonary hypertension of the newborn.

Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidase

Inhaled nitric oxide and bronchopulmonary dysplasia

Inhaled nitric oxide for premature infants with severe respiratory failure

Inhaled nitric oxide for preterm infants: a Marksman's approach

Inhaled prostacyclin for term infants with persistent pulmonary hypertension refractory to inhaled nitric oxide.

Inodilators in nitric oxide resistant persistent pulmonary hypertension of the newborn

Intravenous sildenafil in the treatment of neonates with persistent pulmonary hypertension

Late administration of surfactant replacement therapy increases surfactant protein-B content: a randomized pilot study

Medical and financial impact of a neonatal extracorporeal membrane oxygenation referral center in the nitric oxide era

Mitochondrial oxidant stress increases PDE5 activity in persistent pulmonary hypertension of the newborn.

Neonatal extracorporeal life support: impact of new therapies on survival

Neonatal pulmonary hypertension

Nitric oxide and the developing airway

Nitric oxide decreases endothelin-1 secretion through the activation of soluble guanylate cyclase

Ovine bronchial-derived relaxing factor: changes with development and hyperoxic ventilation.

Oxygen concentration and pulmonary hemodynamics in newborn lambs with pulmonary hypertension.

Paracrine role of soluble guanylate cyclase and type III nitric oxide synthase in ovine fetal pulmonary circulation: a double labeling immunohistochemical study

Pharmacotherapy for pulmonary hypertension

Phosphodiesterases: Emerging Therapeutic Targets for Neonatal Pulmonary Hypertension ⬇️

Pre-term neonate with intestinal failure, feeding issues

Pulmonary Vasodilator Therapy in the NICU: Inhaled Nitric Oxide, Sildenafil, and Other Pulmonary Vasodilating Agents ⬇️

Pulmonary arterial contractility in neonatal lambs increases with 100% oxygen resuscitation

Pulmonary hemodynamics in neonatal lambs resuscitated with 21%, 50%, and 100% oxygen.

Pulmonary hypertension in bronchopulmonary dysplasia

Regulation of phosphodiesterase 3 in the pulmonary arteries during the perinatal period in sheep

Risk Assessment and Monitoring of Chronic Pulmonary Hypertension in Premature Infants

Role of BCL2-associated athanogene 1 in differential sensitivity of human endothelial cells to glucocorticoids.

Selective type 5 phosphodiesterase inhibition alters pulmonary hemodynamics and lung liquid production in near-term fetal lambs.

Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension

The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension.

The role of nitric oxide synthase-derived reactive oxygen species in the altered relaxation of pulmonary arteries from lambs with increased pulmonary blood flow.

Therapeutic approaches using nitric oxide in infants and children.

Type I nitric oxide synthase is decreased in the fetal pulmonary circulation of hypertensive lambs

eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally.