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List of works by Lea T Grinberg

A 44-Year-Old Man with Profound Behavioural Changes ⬇️

scientific article published on July 1, 2012

A manual multiplex immunofluorescence method for investigating neurodegenerative diseases

scientific article published on 31 March 2020

A novel approach for integrative studies on neurodegenerative diseases in human brains.

scientific article published on 3 February 2014

A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques

scientific article

A novel temporal-predominant neuro-astroglial tauopathy associated with TMEM106B gene polymorphism in FTLD/ALS-TDP

scientific article published on 12 December 2020

A review on shared clinical and molecular mechanisms between bipolar disorder and frontotemporal dementia

scientific article published on 20 April 2019

Abnormal alveolar attachments with decreased elastic fiber content in distal lung in fatal asthma.

scientific article published on 19 May 2004

African ancestry protects against Alzheimer's disease-related neuropathology

scientific article

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

scientific article published on 10 December 2015

Alzheimer's disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation

scientific article published on 27 June 2019

Amyloid in dementia associated with familial FTLD: not an innocent bystander

scientific article

An effective fractal-tree closure model for simulating blood flow in large arterial networks

scientific article published on 16 December 2014

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

scientific article published on 20 September 2017

Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.

scientific article published on 31 January 2013

Assessment of factors that confound MRI and neuropathological correlation of human postmortem brain tissue

scientific article published on 12 June 2008

Astrocytic Tau Deposition Is Frequent in Typical and Atypical Alzheimer Disease Presentations

scientific article published on 01 December 2019

Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers

scientific article published on 2 May 2014

Atherosclerosis and dementia: a cross-sectional study with pathological analysis of the carotid arteries

scientific article

Brain atrophy in primary progressive aphasia involves the cholinergic basal forebrain and Ayala's nucleus.

scientific article

Brain bank of the Brazilian aging brain study group - a milestone reached and more than 1,600 collected brains.

scientific article

Brainstem pathology and non-motor symptoms in PD.

scientific article published on 15 September 2009

Brainstem: neglected locus in neurodegenerative diseases.

scientific article

Caucasians and Africans have different susceptibility to neuritic plaques: A population-based clinicopathological study using genetic ancestry-informative markers

Cell number changes in Alzheimer's disease relate to dementia, not to plaques and tangles.

scientific article published on 17 October 2013

Cerebral amyloid angiopathy impact on endothelium

scientific article

Challenges in modern biomarker discovery--17th HUPO BPP workshop: May 24-25, 2012, Sao Paulo, Brazil

scientific article

Cholinergic basal forebrain atrophy predicts amyloid burden in Alzheimer's disease

scientific article

Clinical aspects of neurodegenerative diseases - 15th HUPO BPP Workshop April 8-9, 2011, Bochum, Germany

scientific article published in November 2011

Clinico-pathological discrepancies in the diagnoses of solid malignancies

scientific article

Clinicopathological Study of Patients With C9ORF72-Associated Frontotemporal Dementia Presenting With Delusions

scientific article

Clinicopathological correlations in behavioural variant frontotemporal dementia.

scientific article published on 6 October 2017

Cognitive Correlates of Basal Forebrain Atrophy and Associated Cortical Hypometabolism in Mild Cognitive Impairment

scientific article published on 2 April 2015

Combined enrichment of neuromelanin granules and synaptosomes from human substantia nigra pars compacta tissue for proteomic analysis ⬇️

scientific article published on August 3, 2013

Combining morphometric measurements of the basal forebrain cholinergic system and cortical thickness for better diagnostic accuracy

Combining morphometric measurements of the basal forebrain cholinerigc system and the cortical thickness for better diagnostic accuracy

Complex network-driven view of genomic mechanisms underlying Parkinson's disease: analyses in dorsal motor vagal nucleus, locus coeruleus, and substantia nigra

scientific article

Correction to: Relevance of biomarkers across different neurodegenerative diseases

scientific article published on 09 June 2020

Creating a human brain proteome atlas--13th HUPO BPP Workshop March 30-31, 2010, Ochang, Korea

scientific article published in July 2011

Creating a human brain proteome atlas--14th HUPO BPP workshop September 20-21, 2010, Sydney, Australia

scientific article published in August 2011

Criminal behavior in frontotemporal dementia and Alzheimer disease

scientific article published on March 2015

Depression and cardiovascular risk factors: evidence from a large postmortem sample.

scientific article published on 29 June 2012

Developing new methods to answer old and new questions in neurodegenerative diseases: 21(st) Workshop of the HUPO Brain Proteome Project (HBPP) 23-24 January 2014, Honolulu, Hawaii

scientific article published on 22 April 2014

Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration

scientific article published on 18 July 2016

Distinct tau prion strains propagate in cells and mice and define different tauopathies

scientific article published on 22 May 2014

Don’t die like me: Which proteins are responsible for the selective neuronal vulnerability within the substantia nigra?

scientific article published in 2024

Early diagnosis of neurodegenerative diseases - the long awaited Holy Grail and bottleneck of modern brain research - 19th HUPO BPP workshop: May 22-24, 2013, Dortmund, Germany

scientific article

Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration

scientific article published on 16 February 2018

Effect of laser phototherapy on wound healing following cerebral ischemia by cryogenic injury

scientific article

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

scientific article

Features of Patients With Nonfluent/Agrammatic Primary Progressive Aphasia With Underlying Progressive Supranuclear Palsy Pathology or Corticobasal Degeneration

scientific article published on 25 April 2016

Frontiers in neurodegeneration--new insights and prospects--20th HUPO BPP Workshop: 15 September 2013, Yokohama, Japan

scientific article

Gene expression alterations in the postmortem hippocampus from older patients with bipolar disorder – A hypothesis generating study

scientific article published in 2023

Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene

scientific article

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

scientific article published on 09 February 2019

Germline DNA copy number variation in individuals with Argyrophilic grain disease reveals CTNS as a plausible candidate gene

scientific article published on 8 November 2013

Glutathione-mediated effects of lithium in decreasing protein oxidation induced by mitochondrial complex I dysfunction

scientific article published on 27 September 2014

HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin

scientific article

How to run a brain bank--revisited

scientific article published in September 2008

Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity

scientific article

Improved detection of incipient vascular changes by a biotechnological platform combining post mortem MRI in situ with neuropathology

scientific article published on 16 March 2009

In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology

scientific article

Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain.

scientific article published on 28 June 2018

Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture

scientific article published on 28 October 2016

Is apolipoprotein E epsilon4 allele a higher risk factor for Alzheimer's disease than for vascular dementia? A neuropathological study

scholarly article by Claudia Suemoto et al published July 2011 in Alzheimer's and Dementia

Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials

scientific article published on 01 February 2019

Lower mitochondrial DNA content but not increased mutagenesis associates with decreased base excision repair activity in brains of AD subjects

scientific article published on 22 September 2018

Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

scientific article published on 12 April 2022

Mixed TDP-43 proteinopathy and tauopathy in frontotemporal lobar degeneration: nine case series

scientific article published on 15 October 2018

Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease

scientific article published in 2021

Morphometric measurements of systemic atherosclerosis and visceral fat: Evidence from an autopsy study.

scientific article published on 16 October 2017

Morphometric post-mortem studies in bipolar disorder: possible association with oxidative stress and apoptosis.

scientific article published on 23 December 2010

Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration

scientific article

Neuropathologic heterogeneity in HDDD1: a familial frontotemporal lobar degeneration with ubiquitin-positive inclusions and progranulin mutation

scientific article published in January 2007

Neuropathological diagnoses and clinical correlates in older adults in Brazil: A cross-sectional study.

scientific article

Neuroproteomics: applications in neuroscience and neurology

scientific article published on 6 April 2015

New milestones in the development of characterization tools for neurodegenerative diseases in proteomics: 22nd HUPO BPP Workshop 7 October 2014, Madrid, Spain

scientific article published in February 2015

Novel MRI techniques in the assessment of dementia

scientific article

On the origin of tau seeding activity in Alzheimer's disease.

scientific article published on 23 July 2018

Patterns of neuronal Rhes as a novel hallmark of tauopathies

scientific article published on 07 March 2021

Perivascular Adipose Tissue Inflammation and Coronary Artery Disease: An Autopsy Study Protocol.

scientific article

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

scientific article

Practical utility of amyloid and FDG-PET in an academic dementia center

scientific article published on 18 December 2013

Predicting amyloid status in corticobasal syndrome using modified clinical criteria, magnetic resonance imaging and fluorodeoxyglucose positron emission tomography

scientific article

Prevalence of Mathematical and Visuospatial Learning Disabilities in Patients With Posterior Cortical Atrophy

scientific article published on 9 April 2018

Prevalence of dementia subtypes in a developing country: a clinicopathological study

scientific article published on January 2013

Primary age-related tauopathy (PART): a common pathology associated with human aging

scientific article

Progranulin Mutations as Risk Factors for Alzheimer Disease ⬇️

scientific article published on June 1, 2013

Progresses in neuroproteomics of neurodegenerative diseases--18th HUPO BPP workshop: September 12, 2012, Boston, USA.

scientific article published in January 2013

Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia

scientific article published on 8 January 2018

Relevance of biomarkers across different neurodegenerative

scientific article published on 13 May 2020

Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease

scientific article

Sexual dimorphism in the human olfactory bulb: females have more neurons and glial cells than males

scientific article

Stabilization of the third fibronectin type III domain of human tenascin-C through minimal mutation and rational design

scientific article published on 4 July 2014

Staging Alzheimer's disease progression with multimodality neuroimaging

scientific article published on 22 June 2011

Subregional basal forebrain atrophy in Alzheimer's disease: a multicenter study

scientific article

TDP 43 IS NOT ASSOCIATED WITH NEUROPSYCHIATRIC ALTERATIONS IN COGNITIVELY NORMAL ELDERLY

TDP-43 frontotemporal lobar degeneration and autoimmune disease

scientific article published on 30 March 2013

TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia

scientific article published on 03 January 2014

Temporal variant of frontotemporal dementia in C9orf72 repeat expansion carriers: two case studies

scientific article published on 16 March 2020

The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features

scientific article

The brainstem pathologies of Parkinson's disease and dementia with Lewy bodies.

scientific article

The cholinergic system in mild cognitive impairment and Alzheimer's disease: an in vivo MRI and DTI study

scientific article

The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?

scientific article

The human cerebral cortex is neither one nor many: neuronal distribution reveals two quantitatively different zones in the gray matter, three in the white matter, and explains local variations in cortical folding

scientific article published on 02 September 2013

The role of co-neurotransmitters in sleep and wake regulation

scientific article published on 30 October 2018

Toward a Successful Clinical Neuroproteomics The 11th HUPO Brain Proteome Project Workshop 3 March, 2009, Kolymbari, Greece

scientific article

Toward a pathological definition of vascular dementia ⬇️

scientific article published on December 15, 2010

Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease.

scientific article

Translational proteomics in neurodegenerative diseases--16th HUPO BPP workshop September 5, 2011 Geneva, Switzerland

scientific article published in February 2012

Turning on the Light Within: Subcortical Nuclei of the Isodentritic Core and their Role in Alzheimer's Disease Pathogenesis

scientific article

Typical and atypical pathology in primary progressive aphasia variants

scientific article published on 30 January 2017

Vascular dementia

scholarly article by Amos D. Korczyn et al published 15 November 2012 in Journal of the Neurological Sciences

Vascular dementia: different forms of vessel disorders contribute to the development of dementia in the elderly brain

scientific article

Vascular pathology in the aged human brain

scientific article

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